Searching for up to 100 curated homologs for WP_079649140.1 NCBI__GCF_900167915.1:WP_079649140.1 (258 a.a.)
Found high-coverage hits (≥70%) to 46 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
2vwtA / P76469 Crystal structure of yfau, a metal ion dependent class ii aldolase from escherichia coli k12 - mg-pyruvate product complex (see paper)
33% identity, 96% coverage of query (123 bits)
YfaU / b2245 2-keto-3-deoxy-L-rhamnonate aldolase (EC 4.1.2.53) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
yfaU / P76469 2-keto-3-deoxy-L-rhamnonate aldolase (EC 4.1.2.53) from Escherichia coli (strain K12) (see 4 papers)
RHMA_ECOLI / P76469 2-keto-3-deoxy-L-rhamnonate aldolase; KDR aldolase; 2-dehydro-3-deoxyrhamnonate aldolase; 2-keto-3-deoxy acid sugar aldolase; EC 4.1.2.53 from Escherichia coli (strain K12) (see 2 papers)
P76469 2-keto-3-deoxy-L-rhamnonate aldolase (EC 4.1.2.53) from Escherichia coli (see 3 papers)
33% identity, 96% coverage of query (123 bits)
HPAAL_PARL1 / A7HU24 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
36% identity, 91% coverage of query (121 bits)
GARL_ECO7I / B7NJZ1 5-keto-4-deoxy-D-glucarate aldolase; KDGluc aldolase; KDGlucA; 2-dehydro-3-deoxy-D-glucarate aldolase; 2-keto-3-deoxy-D-glucarate aldolase; 5-dehydro-4-deoxy-D-glucarate aldolase; Alpha-keto-beta-deoxy-D-glucarate aldolase; EC 4.1.2.20 from Escherichia coli O7:K1 (strain IAI39 / ExPEC)
31% identity, 94% coverage of query (118 bits)
1dxeA / P23522 2-dehydro-3-deoxy-galactarate aldolase from escherichia coli (see paper)
31% identity, 94% coverage of query (117 bits)
YhaF / b3126 α-dehydro-β-deoxy-D-glucarate aldolase (EC 4.1.2.20) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
garL / P23522 α-dehydro-β-deoxy-D-glucarate aldolase (EC 4.1.2.20) from Escherichia coli (strain K12) (see 2 papers)
GARL_ECOLI / P23522 5-keto-4-deoxy-D-glucarate aldolase; KDGluc aldolase; KDGlucA; 2-dehydro-3-deoxy-D-glucarate aldolase; 2-keto-3-deoxy-D-glucarate aldolase; 5-dehydro-4-deoxy-D-glucarate aldolase; Alpha-keto-beta-deoxy-D-glucarate aldolase; EC 4.1.2.20 from Escherichia coli (strain K12) (see 3 papers)
31% identity, 94% coverage of query (117 bits)
HPAAL_DELAS / A9BQY3 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Delftia acidovorans (strain DSM 14801 / SPH-1)
33% identity, 97% coverage of query (117 bits)
1dxfA 2-dehydro-3-deoxy-galactarate aldolase from escherichia coli in complex with pyruvate
31% identity, 94% coverage of query (117 bits)
HPAAL_ROSNI / A3SLS0 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM)
31% identity, 98% coverage of query (115 bits)
7et9A Crystal structure of abhpai-zn-pyruvate complex, class ii aldolase, hpai from acinetobacter baumannii (see paper)
31% identity, 96% coverage of query (113 bits)
7etiA Crystal structure of abhpai-zn-pyruvate-4-hydroxybenzaldehyde complex, class ii aldolase, hpai from acinetobacter baumannii
30% identity, 97% coverage of query (113 bits)
7etfA Crystal structure of abhpai-mn-pyruvate-succinic semialdehyde complex, class ii aldolase, hpai from acinetobacter baumannii
30% identity, 97% coverage of query (113 bits)
7eteA Crystal structure of abhpai-mg-(4r)-kdgal complex, class ii aldolase, hpai from acinetobacter baumannii
30% identity, 97% coverage of query (113 bits)
7etdA Crystal structure of abhpai-zn-(4s)-kdglu complex, class ii aldolase, hpai from acinetobacter baumannii
30% identity, 97% coverage of query (113 bits)
7etcA Crystal structure of abhpai-zn-(4r)-kdgal complex, class ii aldolase, hpai from acinetobacter baumannii
30% identity, 97% coverage of query (113 bits)
7etbA Crystal structure of abhpai-mn-pyruvate complex, class ii aldolase, hpai from acinetobacter baumannii
30% identity, 97% coverage of query (113 bits)
7etaA Crystal structure of abhpai-co-pyruvate complex, class ii aldolase, hpai from acinetobacter baumannii
30% identity, 97% coverage of query (113 bits)
7ethA Crystal structure of abhpai-zn-pyruvate-propionaldehyde complex, class ii aldolase, hpai from acinetobacter baumannii
31% identity, 96% coverage of query (113 bits)
HPAA2_PARPJ / B2TGJ0 Hydroxypyruvate/pyruvate aldolase Bphyt_5830; HPA/PA aldolase; EC 4.1.2.- from Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) (Burkholderia phytofirmans)
31% identity, 99% coverage of query (112 bits)
HPAAL_CUPNH / Q0K203 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha)
31% identity, 97% coverage of query (112 bits)
HPAAL_ROSDO / Q16DB5 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)
31% identity, 93% coverage of query (108 bits)
HPAAL_CHRSD / Q1QUJ4 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)
30% identity, 98% coverage of query (108 bits)
HPAAL_PSEAI / A0A081HJP9 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Pseudomonas aeruginosa
31% identity, 96% coverage of query (107 bits)
HPAA1_PARPJ / B2T1L6 Hydroxypyruvate/pyruvate aldolase Bphyt_0320; HPA/PA aldolase; EC 4.1.2.- from Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) (Burkholderia phytofirmans)
33% identity, 95% coverage of query (105 bits)
PAAL_RHIEC / Q2K7V6 Pyruvate aldolase; PA aldolase; EC 4.1.2.- from Rhizobium etli (strain ATCC 51251 / DSM 11541 / JCM 21823 / NBRC 15573 / CFN 42)
31% identity, 95% coverage of query (100 bits)
Build an alignment for WP_079649140.1 and 25 homologs with ≥ 30% identity
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A0A0H3K9Z0 citrate synthase (unknown stereospecificity) (EC 2.3.3.16) from Staphylococcus aureus (see paper)
26% identity, 98% coverage of query (100 bits)
4tv5A / A0A0H3K9Z0 Crystal structure of citrate synthase sbng (see paper)
26% identity, 97% coverage of query (97.1 bits)
HPCH_ECOLC / B1IS70 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; HHED aldolase; 4-hydroxy-2-ketoheptane-1,7-dioate aldolase; HKHD aldolase; EC 4.1.2.52 from Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)
HPCH_ECOLX / Q47098 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; HHED aldolase; 4-hydroxy-2-ketoheptane-1,7-dioate aldolase; HKHD aldolase; EC 4.1.2.52 from Escherichia coli (see 3 papers)
B1IS70 4-hydroxy-2-oxoheptanedioate aldolase (EC 4.1.2.52) from Escherichia coli (see paper)
Q47098 4-hydroxy-2-oxoheptanedioate aldolase (EC 4.1.2.52); 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.39) from Escherichia coli (see 3 papers)
30% identity, 80% coverage of query (93.6 bits)
2v5kA / Q47098 Class ii aldolase hpch - magnesium - oxamate complex (see paper)
30% identity, 80% coverage of query (93.6 bits)
4b5vA Crystal structures of divalent metal dependent pyruvate aldolase, hpai, in complex with 4-hydroxyl-2-ketoheptane-1,7-dioate
30% identity, 80% coverage of query (93.6 bits)
4b5tA Crystal structures of divalent metal dependent pyruvate aldolase, hpai, in complex with ketobutyrate
30% identity, 80% coverage of query (93.6 bits)
4b5sA Crystal structures of divalent metal dependent pyruvate aldolase, hpai, in complex with pyruvate
30% identity, 80% coverage of query (93.6 bits)
HPAAL_DEIRA / Q9RYM1 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)
31% identity, 91% coverage of query (92.8 bits)
HPAAL_RHIWR / A0A9J9HGY6 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; Hydroxy ketoacid aldolase; SwHKA; EC 4.1.2.- from Rhizorhabdus wittichii (strain DSM 6014 / CCUG 31198 / JCM 15750 / NBRC 105917 / EY 4224 / RW1) (Sphingomonas wittichii) (see paper)
31% identity, 88% coverage of query (92.4 bits)
8adqA / A0A9J9HGY6 Crystal structure of holo-swhpa-mg (hydroxy ketone aldolase) from sphingomonas wittichii rw1 in complex with hydroxypyruvate and d- glyceraldehyde (see paper)
31% identity, 88% coverage of query (92.4 bits)
7nr1A Crystal structure of holo-s116a mutant of hydroxy ketone aldolase (swhka) from sphingomonas wittichii rw1 (see paper)
30% identity, 88% coverage of query (92.4 bits)
7o5rA Crystal structure of holo-swhpa-mn (hydroxyketoacid aldolase) from sphingomonas wittichii rw1
31% identity, 88% coverage of query (92.4 bits)
BPHF_RHOJR / O05151 4-hydroxy-2-oxovalerate aldolase; HOA; EC 4.1.3.39 from Rhodococcus jostii (strain RHA1) (see paper)
29% identity, 93% coverage of query (90.5 bits)
KDSGA_PSEPU / P0DOV8 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase; 2-keto-3,6-dideoxy-6-sulfogluconate aldolase; KDSG aldolase; EC 4.1.2.58 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
P0DOV8 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase (EC 4.1.2.58) from Pseudomonas putida (see paper)
29% identity, 86% coverage of query (89.4 bits)
HPAAL_SAGS3 / A3K1H1 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Sagittula stellata (strain ATCC 700073 / DSM 11524 / E-37)
27% identity, 96% coverage of query (89.4 bits)
HPAAL_ACTPL / B4XH86 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae)
25% identity, 98% coverage of query (89.4 bits)
HPAAL_AGRFC / A9CJL2 Hydroxypyruvate/pyruvate aldolase; HPA/PA aldolase; EC 4.1.2.- from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
29% identity, 79% coverage of query (86.3 bits)
4tv6A Crystal structure of citrate synthase variant sbng e151q
25% identity, 97% coverage of query (85.5 bits)
CGHB_CHAGB / Q2HBN5 4-hydroxy-4-methyl-2-oxoglutarate aldolase cghB; Sch210972 biosynthesis cluster protein B; EC 4.1.3.17 from Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus) (see paper)
29% identity, 84% coverage of query (83.2 bits)
TASA_HAPIR / A0A0F7GG11 4-hydroxy-4-methyl-2-oxoglutarate aldolase tasA; Tetramic acid Sch210971/2 biosynthesis cluster protein A; EC 4.1.3.17 from Hapsidospora irregularis (see paper)
28% identity, 93% coverage of query (82.4 bits)
1izcA / Q9UVD4 Crystal structure analysis of macrophomate synthase (see paper)
31% identity, 86% coverage of query (77.4 bits)
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Lawrence Berkeley National Laboratory