Searching for up to 100 curated homologs for WP_080517374.1 NCBI__GCF_000015985.1:WP_080517374.1 (210 a.a.)
Found high-coverage hits (≥70%) to 14 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
lgnG / BAM68210.1 2-keto-3-deoxy-6-phosphogalactonate aldolase lgnG from Paracoccus laeviglucosivorans (see 2 papers)
58% identity, 97% coverage of query (227 bits)
DGOA_RHIME / Q92RN8 Probable 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase; 6-phospho-2-keto-3-deoxygalactonate aldolase; KDPGal; EC 4.1.2.21 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
60% identity, 98% coverage of query (223 bits)
YidU / b4477 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.55; EC 4.1.2.21) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dgoA / Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.55) from Escherichia coli (strain K12) (see 5 papers)
DGOA_ECOLI / Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase; 6-phospho-2-keto-3-deoxygalactonate aldolase; KDPGal; EC 4.1.2.21 from Escherichia coli (strain K12) (see 3 papers)
Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.21) from Escherichia coli (see paper)
dgoA / RF|YP_026238 2-dehydro-3-deoxy-6-phosphogalactonate aldolase from Escherichia coli K12 (see 2 papers)
44% identity, 94% coverage of query (151 bits)
2v82A / Q6BF16 Kdpgal complexed to kdpgal (see paper)
44% identity, 94% coverage of query (151 bits)
1wa3D / Q9WXS1 Mechanism of the class i kdpg aldolase (see paper)
33% identity, 90% coverage of query (99.0 bits)
TM0066 / Q9WXS1 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16; EC 4.1.2.55) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
33% identity, 90% coverage of query (98.6 bits)
CA265_RS19860 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Pedobacter sp. GW460-11-11-14-LB5
30% identity, 74% coverage of query (75.9 bits)
Build an alignment for WP_080517374.1 and 7 homologs with ≥ 30% identity
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ALKH_BACSU / P50846 KHG/KDPG aldolase; EC 4.1.3.16; EC 4.1.2.14 from Bacillus subtilis (strain 168) (see paper)
29% identity, 81% coverage of query (74.7 bits)
6oviA / Q5ZYF2 Crystal structure of kdpg aldolase from legionella pneumophila with pyruvate captured at low ph as a covalent carbinolamine intermediate
28% identity, 74% coverage of query (53.9 bits)
Kga / b1850 KHG/KDPG aldolase (EC 4.1.2.55; EC 4.1.2.14; EC 4.1.3.42; EC 4.1.1.112) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
eda / P0A955 KHG/KDPG aldolase (EC 4.1.2.55; EC 4.1.3.42; EC 4.1.1.112) from Escherichia coli (strain K12) (see 2 papers)
ALKH_ECOLI / P0A955 KHG/KDPG aldolase; EC 4.1.3.16; EC 4.1.2.14 from Escherichia coli (strain K12) (see 5 papers)
P0A955 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16); (4S)-4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.42) from Escherichia coli (see 5 papers)
eda / RF|NP_416364 KHG/KDPG aldolase; EC 4.1.2.14; EC 4.1.3.16 from Escherichia coli K12 (see 4 papers)
28% identity, 71% coverage of query (52.4 bits)
1euaA Schiff base intermediate in kdpg aldolase from escherichia coli
28% identity, 71% coverage of query (52.4 bits)
Q0K1X1 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Cupriavidus necator (see paper)
30% identity, 71% coverage of query (51.6 bits)
2c0aB / P0A955 Mechanism of the class i kdpg aldolase (see paper)
28% identity, 71% coverage of query (50.4 bits)
1wauA Structure of kdpg aldolase e45n mutant
28% identity, 71% coverage of query (50.4 bits)
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Lawrence Berkeley National Laboratory