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Searching for up to 100 curated homologs for WP_083944983.1 NCBI__GCF_000934765.1:WP_083944983.1 (322 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

A0A3G4RI75 glucokinase (EC 2.7.1.2) from Methylomonas methanica (see paper)
    35% identity, 96% coverage of query (149 bits)

G4T1H4 glucokinase (EC 2.7.1.2) from Methylotuvimicrobium alcaliphilum (see paper)
    34% identity, 96% coverage of query (149 bits)

Glk / b2388 glucokinase (EC 2.7.1.1; EC 2.7.1.2; EC 2.7.1.8) from Escherichia coli K-12 substr. MG1655 (see 11 papers)
glk / P0A6V8 glucokinase (EC 2.7.1.1; EC 2.7.1.8) from Escherichia coli (strain K12) (see 11 papers)
GLK_ECOLI / P0A6V8 Glucokinase; Glucose kinase; EC 2.7.1.2 from Escherichia coli (strain K12) (see paper)
    33% identity, 97% coverage of query (142 bits)

1sz2B / P0A6V9 Crystal structure of e. Coli glucokinase in complex with glucose (see paper)
    33% identity, 95% coverage of query (142 bits)

Build an alignment

Build an alignment for WP_083944983.1 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

GL50803_8826 / E2RU42 glucokinase (EC 2.7.1.1) from Giardia intestinalis (strain ATCC 50803 / WB clone C6) (see 3 papers)
    29% identity, 97% coverage of query (138 bits)

PS417_22685 Glucokinase (EC 2.7.1.2) from Pseudomonas simiae WCS417
    31% identity, 96% coverage of query (124 bits)

Dshi_1655 glucokinase (EC 2.7.1.2) from Dinoroseobacter shibae DFL-12
    29% identity, 95% coverage of query (119 bits)

glk / AAC43672.1 glucokinase from Brucella abortus (see paper)
    28% identity, 95% coverage of query (116 bits)

PGA1_c05420 glucokinase (EC 2.7.1.2) from Phaeobacter inhibens BS107
    31% identity, 98% coverage of query (95.9 bits)

5brfA Crystal structure of trypanosoma cruzi glucokinase in complex with inhibitor hpop-glcn
    26% identity, 95% coverage of query (65.1 bits)

Q4E4E1 glucokinase (EC 2.7.1.2) from Trypanosoma cruzi (see 3 papers)
    26% identity, 95% coverage of query (63.9 bits)

5brhA Crystal structure of trypanosoma cruzi glucokinase in complex with inhibitor dbt-glcn
    26% identity, 95% coverage of query (63.9 bits)

5breA Crystal structure of trypanosoma cruzi glucokinase in complex with inhibitor cbz-glcn
    26% identity, 95% coverage of query (63.9 bits)

5brdA Crystal structure of trypanosoma cruzi glucokinase in complex with inhibitor benz-glcn
    26% identity, 95% coverage of query (63.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory