Searching for up to 100 curated homologs for WP_084200258.1 NCBI__GCF_002869505.1:WP_084200258.1 (658 a.a.)
Found high-coverage hits (≥70%) to 43 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
atuF / Q9HZV6 cis-geranyl-CoA carboxylase α-subunit (EC 6.4.1.5) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
58% identity, 99% coverage of query (723 bits)
Q9FAF5 biotin carboxylase (EC 6.3.4.14) from Myxococcus xanthus (see paper)
55% identity, 84% coverage of query (577 bits)
MCCC1 / Q96RQ3 3-methylcrotonyl-CoA carboxylase α subunit (EC 6.4.1.4) from Homo sapiens (see 4 papers)
MCCA_HUMAN / Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Homo sapiens (Human) (see 15 papers)
45% identity, 99% coverage of query (569 bits)
8xl6A / Q96RQ3 Structure of human 3-methylcrotonyl-coa carboxylase at apo-state (mcc- apo)
45% identity, 99% coverage of query (561 bits)
Sama_1359 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Shewanella amazonensis SB2B
47% identity, 99% coverage of query (559 bits)
MCCA_MOUSE / Q99MR8 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Mus musculus (Mouse) (see paper)
46% identity, 99% coverage of query (555 bits)
AO356_01595 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2C3
48% identity, 99% coverage of query (545 bits)
Pf6N2E2_2194 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2E2
48% identity, 99% coverage of query (539 bits)
liuD / Q9I299 methylcrotonyl-CoA carboxylase α-subunit (EC 6.4.1.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I299 methylcrotonoyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.4) from Pseudomonas aeruginosa (see 3 papers)
48% identity, 99% coverage of query (537 bits)
ACCA1_MYCTU / P9WPQ3 Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit; EC 6.3.4.14 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
CAA79609.1 biotin carboxyl carrier protein from Mycobacterium tuberculosis (see paper)
46% identity, 98% coverage of query (535 bits)
MCCA_ARATH / Q42523 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q42523 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) from Arabidopsis thaliana (see 2 papers)
42% identity, 99% coverage of query (534 bits)
Pf1N1B4_3984 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N1B4
47% identity, 99% coverage of query (533 bits)
8j78I / Q96RQ3 Human 3-methylcrotonyl-coa carboxylase in bccp-h2 state
44% identity, 99% coverage of query (526 bits)
MCCA_ORYSJ / Q2QMG2 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
41% identity, 99% coverage of query (513 bits)
Dsui_0516 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dechlorosoma suillum PS
45% identity, 98% coverage of query (491 bits)
SM_b21124 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Sinorhizobium meliloti 1021
44% identity, 98% coverage of query (486 bits)
8xl5A Structure of human propionyl-coa carboxylase in complex with propionyl-coa (pcc-pco)
41% identity, 98% coverage of query (485 bits)
7ybuA / P05165 Human propionyl-coenzyme a carboxylase (see paper)
41% identity, 98% coverage of query (484 bits)
PCCA / P05165 propionyl-CoA carboxylase α chain, mitochondrial (EC 6.4.1.3) from Homo sapiens (see 4 papers)
PCCA_HUMAN / P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Homo sapiens (Human) (see 11 papers)
P05165 propionyl-CoA carboxylase (subunit 1/2) (EC 6.4.1.3) from Homo sapiens (see paper)
41% identity, 98% coverage of query (484 bits)
PCCA_PIG / P0DTA4 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Sus scrofa (Pig) (see paper)
41% identity, 98% coverage of query (483 bits)
Pcca / P14882 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Rattus norvegicus (see paper)
41% identity, 98% coverage of query (477 bits)
PCCA_MOUSE / Q91ZA3 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Mus musculus (Mouse) (see paper)
41% identity, 98% coverage of query (473 bits)
8rthA / Q57YQ4 Trypanosoma brucei 3-methylcrotonyl-coa carboxylase (see paper)
42% identity, 95% coverage of query (469 bits)
mccA 3-methylcrotonyl-CoA carboxylase biotin-containig subunit; EC 6.4.1.4 from Emericella nidulans (see paper)
mccA / AAR23110.1 3-methylcrotonyl-CoA carboxylase biotin-containing subunit from Aspergillus nidulans (see paper)
40% identity, 98% coverage of query (454 bits)
8sgxX / A0A640KC69 Leishmania tarentolae propionyl-coa carboxylase (alpha-4-beta-6) (see paper)
40% identity, 98% coverage of query (453 bits)
accC / A9W9X0 biotin carboxylase (EC 6.3.4.14) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
A9W9X0 biotin carboxylase (EC 6.3.4.14) from Chloroflexus aurantiacus (see paper)
42% identity, 99% coverage of query (426 bits)
PYC_MOUSE / Q05920 Pyruvate carboxylase, mitochondrial; Pyruvic carboxylase; PCB; EC 6.4.1.1 from Mus musculus (Mouse) (see paper)
45% identity, 72% coverage of query (394 bits)
PC / P11498 pyruvate carboxylase, mitochondrial (EC 6.4.1.1) from Homo sapiens (see 5 papers)
PYC_HUMAN / P11498 Pyruvate carboxylase, mitochondrial; Pyruvic carboxylase; PCB; EC 6.4.1.1 from Homo sapiens (Human) (see 5 papers)
P11498 pyruvate carboxylase (EC 6.4.1.1) from Homo sapiens (see 5 papers)
44% identity, 73% coverage of query (389 bits)
7wtbB / P11498 Cryo-em structure of human pyruvate carboxylase with acetyl-coa (see paper)
44% identity, 73% coverage of query (389 bits)
7wtdC Cryo-em structure of human pyruvate carboxylase with acetyl-coa in the intermediate state 1
44% identity, 73% coverage of query (389 bits)
8jxnJ Human 3-methylcrotonyl-coa carboxylase in bccp-h1 state with mcoa
41% identity, 71% coverage of query (349 bits)
Build an alignment for WP_084200258.1 and 31 homologs with ≥ 30% identity
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ACAC_YEAST / Q00955 Acetyl-CoA carboxylase; ACC; Fatty acid synthetase 3; mRNA transport-defective protein 7; EC 6.4.1.2; EC 6.3.4.14 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
Q00955 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (EC 6.4.1.2) from Saccharomyces cerevisiae (see 6 papers)
28% identity, 95% coverage of query (243 bits)
P11029 Acetyl-CoA carboxylase; ACC; EC 6.4.1.2; EC 6.3.4.14 from Gallus gallus (Chicken)
27% identity, 95% coverage of query (241 bits)
ACC1 / Q38970 acetyl-CoA carboxylase 1 (EC 6.4.1.2) from Arabidopsis thaliana (see 2 papers)
ACC1_ARATH / Q38970 Acetyl-CoA carboxylase 1; AtACC1; Protein EMBRYO DEFECTIVE 22; Protein GURKE; Protein PASTICCINO 3; EC 6.4.1.2; EC 6.3.4.14 from Arabidopsis thaliana (Mouse-ear cress) (see 10 papers)
Q38970 acetyl-CoA carboxylase (EC 6.4.1.2) from Arabidopsis thaliana (see paper)
27% identity, 99% coverage of query (238 bits)
ACC1 / Q13085 acetyl-CoA carboxylase 1 (EC 2.1.3.15; EC 6.4.1.2; EC 6.3.4.14) from Homo sapiens (see 6 papers)
ACACA_HUMAN / Q13085 Acetyl-CoA carboxylase 1; ACC1; Acetyl-Coenzyme A carboxylase alpha; ACC-alpha; EC 6.4.1.2 from Homo sapiens (Human) (see 8 papers)
Q13085 acetyl-CoA carboxylase (EC 6.4.1.2) from Homo sapiens (see 13 papers)
27% identity, 95% coverage of query (235 bits)
8xkzC / Q13085 Core region of the citrate-induced human acetyl-coa carboxylase 1 filament (acc1-citrate) (see paper)
27% identity, 95% coverage of query (235 bits)
ACACB_MOUSE / E9Q4Z2 Acetyl-CoA carboxylase 2; ACC-beta; EC 6.4.1.2 from Mus musculus (Mouse) (see 10 papers)
29% identity, 96% coverage of query (234 bits)
ACACA_MOUSE / Q5SWU9 Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; Acetyl-CoA carboxylase 265; EC 6.4.1.2 from Mus musculus (Mouse) (see 4 papers)
Q5SWU9 acetyl-CoA carboxylase (EC 6.4.1.2) from Mus musculus (see 2 papers)
27% identity, 95% coverage of query (234 bits)
5cslB / Q00955 Crystal structure of the 500 kd yeast acetyl-coa carboxylase holoenzyme dimer (see paper)
27% identity, 94% coverage of query (233 bits)
ACACA_RAT / P11497 Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; EC 6.4.1.2 from Rattus norvegicus (Rat) (see 4 papers)
27% identity, 95% coverage of query (228 bits)
ACAC_SCHPO / P78820 Acetyl-CoA carboxylase; ACC; Cell untimely torn protein 6; EC 6.4.1.2; EC 6.3.4.14 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
cut6 / RF|NP_593271.1 acetyl-CoA/biotin carboxylase; EC 6.3.4.14 from Schizosaccharomyces pombe (see 2 papers)
28% identity, 96% coverage of query (227 bits)
5cslA / Q00955 Crystal structure of the 500 kd yeast acetyl-coa carboxylase holoenzyme dimer (see paper)
27% identity, 95% coverage of query (224 bits)
ACC2 / O00763 Biotin carboxylase (EC 2.1.3.15; EC 6.4.1.2; EC 6.3.4.14) from Homo sapiens (see 6 papers)
ACACB_HUMAN / O00763 Acetyl-CoA carboxylase 2; ACC-beta; EC 6.4.1.2 from Homo sapiens (Human) (see 12 papers)
O00763 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (EC 6.4.1.2) from Homo sapiens (see 11 papers)
28% identity, 96% coverage of query (221 bits)
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Lawrence Berkeley National Laboratory