Sites on a Tree

 

Searching for up to 100 curated homologs for WP_085122217.1 NCBI__GCF_900177295.1:WP_085122217.1 (252 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.4.10 / Q8DQH8 ABC transporter ATP-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    42% identity, 99% coverage of query (199 bits)

PGA1_c12640 D-lactate transporter, ATP-binding component from Phaeobacter inhibens BS107
    40% identity, 99% coverage of query (194 bits)

HSERO_RS00895 L-proline ABC transporter, ATPase component 1 from Herbaspirillum seropedicae SmR1
    41% identity, 98% coverage of query (185 bits)

LivG / b3455 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
LivG / P0A9S7 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG (EC 7.4.2.2) from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.4.1 / P0A9S7 High-affinity branched-chain amino acid transport ATP-binding protein LivG aka B3455, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 4 papers)
    40% identity, 97% coverage of query (184 bits)

Pf6N2E2_2925 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, ATPase component 1 LivG from Pseudomonas fluorescens FW300-N2E2
    41% identity, 97% coverage of query (184 bits)

TC 3.A.1.4.6 / Q7A2H0 NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB) (see paper)
    40% identity, 98% coverage of query (180 bits)

TC 3.A.1.4.11 / Q6N8W1 Putative branched-chain amino acid transport system ATP-binding protein, component of The phenylpropeneoid uptake porter, CouPSTW from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
    44% identity, 98% coverage of query (179 bits)

TC 3.A.1.4.8 / P21629 High-affinity branched-chain amino acid transport ATP-binding protein BraF, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    40% identity, 97% coverage of query (178 bits)

Ac3H11_1693 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, ATPase component 1 from Acidovorax sp. GW101-3H11
    39% identity, 97% coverage of query (172 bits)

TC 3.A.1.4.2 / Q55164 NatA aka BRAF aka SLR0467, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE (see paper)
    39% identity, 97% coverage of query (171 bits)

TC 3.A.1.4.7 / Q92TN3 ABC transporter, ATP-binding protein, component of The protocatechuate (3,4-dihydroxybenzoate) uptake porter, PcaMNVWX from Rhizobium meliloti (strain 1021)
    39% identity, 99% coverage of query (170 bits)

Pf6N2E2_3577 ABC transporter for L-leucine/L-isoleucine/D-alanine, ATPase component 1 LivG from Pseudomonas fluorescens FW300-N2E2
    38% identity, 98% coverage of query (164 bits)

braF / CAB75551.1 ATPase from Rhizobium leguminosarum bv. viciae (see 2 papers)
    39% identity, 97% coverage of query (163 bits)

AZOBR_RS08245 L-proline and D-alanine ABC transporter, ATPase component 1 from Azospirillum brasilense Sp245
    40% identity, 97% coverage of query (161 bits)

1g6hA / Q58663 Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
    34% identity, 98% coverage of query (155 bits)

TC 3.A.1.4.5 / Q8NRV8 UrtD, component of The high affinity urea/thiourea/hydroxyurea porter from Corynebacterium glutamicum (see paper)
    38% identity, 96% coverage of query (154 bits)

1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter
    34% identity, 98% coverage of query (153 bits)

TC 3.A.1.4.9 / Q0S719 ABC amino acid transporter, ATP-binding, component of Uptake transporter, CamABCD of cholate (steroid) metabolites, 1β(2'-propanoate)-3aα-H-4α(3"(R)-hydroxy-3"-propanoate)-7aβ-methylhexahydro-5-indanone and a desaturated analog from Rhodococcus sp. (strain RHA1)
    38% identity, 98% coverage of query (148 bits)

TC 3.A.1.4.3 / Q8VM83 BraF aka Bra2F, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae) (see paper)
    34% identity, 98% coverage of query (146 bits)

Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
    35% identity, 92% coverage of query (144 bits)

TC 3.A.1.1.14 / Q97UF2 AraV, component of Arabinose, fructose, xylose porter from Sulfolobus solfataricus (see paper)
    34% identity, 93% coverage of query (140 bits)

HSERO_RS03640 D-mannose ABC transporter, ATPase component from Herbaspirillum seropedicae SmR1
    35% identity, 95% coverage of query (140 bits)

PHNT_SALTY / P96063 Putative 2-aminoethylphosphonate import ATP-binding protein PhnT from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.11.5 / P96063 PhnT aka STM0428, component of 2-aminoethyl phosphonate porter from Salmonella typhimurium (see 2 papers)
    39% identity, 85% coverage of query (139 bits)

lptB / Q7CPN9 LPS export ABC transporter ATP-binding protein (EC 7.5.2.5) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 9 papers)
    32% identity, 98% coverage of query (136 bits)

TC 3.A.1.24.4 / Q8NSN2 Methionine import ATP-binding protein metN, component of L-Methionine uptake porter, MetQNI from Corynebacterium glutamicum (see paper)
    36% identity, 90% coverage of query (135 bits)

TC 3.A.1.4.10 / Q8DQH7 ABC transporter ATP-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    35% identity, 98% coverage of query (133 bits)

A0A071L2Z5 ABC-type lipopolysaccharide transporter (EC 7.5.2.5) from Pseudomonas aeruginosa (see paper)
TC 3.A.1.152.1 / Q9HVV6 Probable ATP-binding component of ABC transporter, component of LPS export system, LptF (M), LptG (M) and LptB (C) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
    32% identity, 98% coverage of query (132 bits)

TC 3.A.1.6.3 / P0A4W2 Sulfate/thiosulfate import ATP-binding protein CysA aka RV2397C aka MT2468 aka MTCY253.24, component of Sulfate porter from Mycobacterium tuberculosis (see 3 papers)
    34% identity, 96% coverage of query (131 bits)

7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
    34% identity, 93% coverage of query (131 bits)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
    34% identity, 93% coverage of query (131 bits)

6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
    34% identity, 93% coverage of query (131 bits)

lptB / O25417 lipopolysaccharide transport system ATP-binding protein LptB (EC 7.5.2.5) from Helicobacter pylori (strain ATCC 700392 / 26695) (see paper)
    32% identity, 98% coverage of query (130 bits)

Build an alignment

Build an alignment for WP_085122217.1 and 32 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
    29% identity, 98% coverage of query (129 bits)

AZOBR_RS08250 L-proline and D-alanine ABC transporter, ATPase component 2 from Azospirillum brasilense Sp245
    35% identity, 96% coverage of query (129 bits)

1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
    32% identity, 93% coverage of query (125 bits)

6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
    33% identity, 96% coverage of query (120 bits)

6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
    33% identity, 96% coverage of query (120 bits)

6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
    33% identity, 96% coverage of query (120 bits)

6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
    32% identity, 96% coverage of query (119 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    31% identity, 98% coverage of query (119 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    31% identity, 98% coverage of query (119 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    31% identity, 98% coverage of query (119 bits)

RbsA / b3749 ribose ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsA / P04983 ribose ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 2 papers)
RBSA_ECOLI / P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.1 / P04983 RbsA aka B3749, component of Ribose porter from Escherichia coli (see 6 papers)
rbsA / GB|AAC76772.1 ribose transport, ATP-binding protein RbsA; EC 3.6.3.17 from Escherichia coli K12 (see 7 papers)
    29% identity, 99% coverage of query (119 bits)

6b89A E. Coli lptb in complex with adp and novobiocin
    32% identity, 96% coverage of query (118 bits)

4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
    32% identity, 96% coverage of query (118 bits)

2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
    31% identity, 93% coverage of query (117 bits)

PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
    32% identity, 92% coverage of query (117 bits)

6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
    32% identity, 96% coverage of query (117 bits)

1ji0A / Q9X0M3 Crystal structure analysis of the abc transporter from thermotoga maritima
    31% identity, 97% coverage of query (115 bits)

4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
    30% identity, 92% coverage of query (114 bits)

3c4jA Abc protein artp in complex with atp-gamma-s
    30% identity, 93% coverage of query (112 bits)

3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
    30% identity, 93% coverage of query (112 bits)

2olkA Abc protein artp in complex with adp-beta-s
    30% identity, 93% coverage of query (112 bits)

2oljA Abc protein artp in complex with adp/mg2+
    30% identity, 93% coverage of query (112 bits)

4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
    29% identity, 92% coverage of query (111 bits)

1g291 / Q9YGA6 Malk (see paper)
    30% identity, 93% coverage of query (108 bits)

4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
    33% identity, 92% coverage of query (108 bits)

MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
    30% identity, 92% coverage of query (106 bits)

6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
    30% identity, 92% coverage of query (105 bits)

3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
    30% identity, 92% coverage of query (105 bits)

3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
    30% identity, 92% coverage of query (105 bits)

LolD / b1117 lipoprotein release complex - ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 2 papers)
LolD / P75957 lipoprotein release complex - ATP binding subunit from Escherichia coli (strain K12) (see paper)
LOLD_ECOLI / P75957 Lipoprotein-releasing system ATP-binding protein LolD; EC 7.6.2.- from Escherichia coli (strain K12) (see paper)
TC 3.A.1.125.1 / P75957 LolD aka B1117, component of Lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope) (see 1.B.46; Narita et al., 2003; Ito et al., 2006; Watanabe et al., 2007). The structure of ligand-bound LolCDE has been solved (Ito et al., 2006). LolC and LolE each have 4 TMSs (1+3). Unlike most ATP binding cassette transporters mediating the transmembrane flux of substrates, the LolCDE complex catalyzes the extrusion of lipoproteins anchored to the outer leaflet of the inner membrane. The LolCDE complex is unusual in that it can be purified as a liganded form, which is an intermediate of the lipoprotein release reaction (Taniguchi and Tokuda, 2008). LolCDE has been reconstituted from separated subunits from Escherichia coli (see 5 papers)
lolD / GB|BAA35937.2 lipoprotein releasing system, ATP-binding protein; EC 3.6.3.- from Escherichia coli K12 (see 5 papers)
    28% identity, 90% coverage of query (104 bits)

7mdyC Lolcde nucleotide-bound
    28% identity, 90% coverage of query (104 bits)

7v8iD / P75957 Lolcd(e171q)e with bound amppnp in nanodiscs (see paper)
    28% identity, 90% coverage of query (103 bits)

8wm7D / Q8YZ75 Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with signalling protein pii (see paper)
    30% identity, 88% coverage of query (102 bits)

7arlD Lolcde in complex with lipoprotein and adp
    28% identity, 89% coverage of query (102 bits)

FTSE_STRP2 / A0A0H2ZM82 Cell division ATP-binding protein FtsE from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) (see 3 papers)
FTSE_STRR6 / Q8DQH4 Cell division ATP-binding protein FtsE from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
6z4wA / Q8DQH4 Ftse structure from streptococcus pneumoniae in complex with adp (space group p 1) (see paper)
    28% identity, 94% coverage of query (102 bits)

8w9mD Cryo-em structure of the cyanobacterial nitrate transporter nrtbcd in complex with atp
    30% identity, 88% coverage of query (101 bits)

MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    27% identity, 93% coverage of query (100 bits)

7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
    30% identity, 89% coverage of query (100 bits)

7w79A Heme exporter hrtba in complex with mn-amppnp
    32% identity, 84% coverage of query (100 bits)

7w78A / Q6NEF2 Heme exporter hrtba in complex with mg-amppnp (see paper)
    32% identity, 84% coverage of query (100 bits)

FtsE / b3463 cell division protein FtsE from Escherichia coli K-12 substr. MG1655 (see 9 papers)
FTSE_ECOLI / P0A9R7 Cell division ATP-binding protein FtsE from Escherichia coli (strain K12) (see 4 papers)
ftsE cell division ATP-binding protein ftsE from Escherichia coli K12 (see 3 papers)
    30% identity, 88% coverage of query (99.8 bits)

7lkpA Structure of atp-free human abca4
    29% identity, 86% coverage of query (99.8 bits)

8w6iD / P0A9R7 Cryo-em structure of escherichia coli str k12 ftsex complex with atp- gamma-s in peptidisc
    30% identity, 88% coverage of query (99.8 bits)

7e7oA / P78363 Cryo-em structure of human abca4 in nrpe-bound state (see paper)
    30% identity, 85% coverage of query (99.4 bits)

6xgyA Crystal structure of e. Coli mlafb abc transport subunits in the dimeric state
    30% identity, 94% coverage of query (99.4 bits)

7ch6C / P63386 Cryo-em structure of e.Coli mlafeb with amppnp (see paper)
    30% identity, 94% coverage of query (99.4 bits)

FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
    29% identity, 95% coverage of query (99.4 bits)

8f5bA / P78363 Human abca4 structure in complex with amp-pnp
    30% identity, 85% coverage of query (98.6 bits)

8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
    30% identity, 88% coverage of query (98.6 bits)

8hprD Lpqy-sugabc in state 4
    30% identity, 88% coverage of query (98.6 bits)

8igqA / O05779 Cryo-em structure of mycobacterium tuberculosis adp bound ftsex/ripc complex in peptidisc (see paper)
    30% identity, 90% coverage of query (98.6 bits)

8hd0A Cell divisome spg hydrolysis machinery ftsex-envc
    29% identity, 88% coverage of query (98.6 bits)

8hprC Lpqy-sugabc in state 4
    30% identity, 88% coverage of query (98.6 bits)

FTSE_MYCTA / A5U7B7 Cell division ATP-binding protein FtsE from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) (see 2 papers)
    30% identity, 90% coverage of query (98.2 bits)

7cgnB The overall structure of the mlafedb complex in atp-bound eqtall conformation (mutation of e170q on mlaf)
    30% identity, 94% coverage of query (98.2 bits)

8iddA Cryo-em structure of mycobacterium tuberculosis atp bound ftsex/ripc complex in peptidisc
    30% identity, 90% coverage of query (98.2 bits)

8wm7C / Q8YZ76 Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with signalling protein pii (see paper)
    29% identity, 88% coverage of query (98.2 bits)

ABCA4_HUMAN / P78363 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM proteinv; RmP; Retinal-specific ATP-binding cassette transporter; Stargardt disease protein; EC 7.6.2.1 from Homo sapiens (Human) (see 38 papers)
TC 3.A.1.211.2 / P78363 The retinal-specific ABC transporter (RIM protein, ABCR or ABCA4) (Stargardt's disease protein, involved in retinal/macular degeneration) in the rod outer segment. Changes in the oligomeric state of the nucleotide binding domains of ABCR are coupled to ATP hydrolysis and might represent a signal for the TMDs of ABCR to export the bound substrate (Biswas-Fiss 2006). The ABCA4 porter flips N-retinylidene-phosphatidylethanolamine, a product generated from the photobleaching of rhodopsin, from the lumen to the cytoplasmic side of disc membranes following the photobleaching of rhodopsin, insuring that retinoids do not accumulate in disc membranes (Molday, 2007; Molday et al. 2009; Tsybovsky et al. 2013). It also transports several vitamin A derivatives (Sun, 2011) and phosphatidylethanolamine in the same direction. Mutations, known to cause Stargardt disease, decrease N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine transport activities (Quazi et al. 2012). It functions as an inwardly directed retinoid flippase in the visual cycle from Homo sapiens (Human) (see 28 papers)
    30% identity, 85% coverage of query (97.8 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    26% identity, 93% coverage of query (97.8 bits)

1f3oA / Q58206 Crystal structure of mj0796 atp-binding cassette (see paper)
    27% identity, 88% coverage of query (97.4 bits)

7lkzA Structure of atp-bound human abca4
    29% identity, 85% coverage of query (97.4 bits)

6z67B Ftse structure of streptococcus pneumoniae in complex with amppnp at 2.4 a resolution
    27% identity, 94% coverage of query (97.4 bits)

5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
    33% identity, 94% coverage of query (97.4 bits)

7e7qA / P78363 Cryo-em structure of human abca4 in atp-bound state (see paper)
    29% identity, 85% coverage of query (97.1 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    26% identity, 92% coverage of query (96.7 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    26% identity, 92% coverage of query (96.7 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    26% identity, 92% coverage of query (96.7 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    26% identity, 92% coverage of query (96.7 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory