Searching for up to 100 curated homologs for WP_086510087.1 NCBI__GCF_002151265.1:WP_086510087.1 (311 a.a.)
Found high-coverage hits (≥70%) to 48 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
3kboA / Q8ZQ30 2.14 angstrom crystal structure of putative oxidoreductase (ycdw) from salmonella typhimurium in complex with NADP
40% identity, 100% coverage of query (208 bits)
5vg6B / A7IIH0 Crystal structure of d-isomer specific 2-hydroxyacid dehydrogenase from xanthobacter autotrophicus py2 in complex with NADPH and mes.
41% identity, 98% coverage of query (202 bits)
7jqhA / A0A140NAE3 Structure of wild type glyoxylate/hydroxypyruvate reductase a from escherichia coli in complex with phosphate and NADP+
41% identity, 97% coverage of query (201 bits)
GhrA / b1033 glyoxylate/hydroxypyruvate reductase A (EC 1.1.1.79) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ghrA / P75913 glyoxylate/hydroxypyruvate reductase A (EC 1.1.1.79) from Escherichia coli (strain K12) (see 4 papers)
GHRA_ECOLI / P75913 Glyoxylate/hydroxypyruvate reductase A; 2-ketoacid reductase; EC 1.1.1.79; EC 1.1.1.81 from Escherichia coli (strain K12) (see paper)
41% identity, 97% coverage of query (201 bits)
7jqiA Structure of wild type glyoxylate/hydroxypyruvate reductase a from escherichia coli in complex with alpha-ketoglutarate and NADP+
41% identity, 97% coverage of query (201 bits)
6p35A 2.5 angstrom structure of wild type glyoxylate/hydroxypyruvate reductase a from escherichia coli in complex with 2-keto arginine and NADP
41% identity, 97% coverage of query (201 bits)
4zqbB / Q3IWN8 Crystal structure of NADP-dependent dehydrogenase from rhodobactersphaeroides in complex with NADP and sulfate
40% identity, 96% coverage of query (174 bits)
Q92T34 hydroxypyruvate reductase (EC 1.1.1.81) from Sinorhizobium meliloti (see paper)
37% identity, 95% coverage of query (155 bits)
4weqA / Q92T34 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc02828 (smghra) from sinorhizobium meliloti in complex with NADP and sulfate (see paper)
37% identity, 95% coverage of query (155 bits)
4z0pA Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc02828 (smghra) from sinorhizobium meliloti in complex with NADPH and oxalate
37% identity, 95% coverage of query (155 bits)
5bqfA / Q2KDT2 Probable 2-hydroxyacid dehydrogenase from rhizobium etli cfn 42 in complex with NADP, hepes and l(+)-tartaric acid
33% identity, 90% coverage of query (126 bits)
4xcvA Probable 2-hydroxyacid dehydrogenase from rhizobium etli cfn 42 in complex with NADPH
33% identity, 90% coverage of query (126 bits)
5tsdA Crystal structure of NADPH-dependent 2-hydroxyacid dehydrogenase from rhizobium etli cfn 42 in complex with NADPH and oxalate
33% identity, 90% coverage of query (126 bits)
Sama_3039 Phosphoglycerate dehydrogenase (EC 1.1.1.95) from Shewanella amazonensis SB2B
30% identity, 100% coverage of query (109 bits)
Build an alignment for WP_086510087.1 and 14 homologs with ≥ 30% identity
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O58256 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pyrococcus horikoshii (see paper)
29% identity, 75% coverage of query (86.3 bits)
serA / GB|AAC83943.1 phosphoglycerate dehydrogenase; EC 1.1.1.95 from Bacillus subtilis (see paper)
serA / AAC83943.1 phosphoglycerate dehydrogenase from Bacillus subtilis (see 3 papers)
28% identity, 88% coverage of query (85.1 bits)
hprA / Q59516 hydroxypyruvate reductase subunit (EC 1.1.1.81) from Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) (see 2 papers)
28% identity, 76% coverage of query (80.1 bits)
A0A0A7RFJ3 hydroxyphenylpyruvate reductase (EC 1.1.1.237) from Salvia miltiorrhiza (see paper)
31% identity, 76% coverage of query (77.0 bits)
TkrA / b3553 glyoxylate reductase (EC 1.1.1.79; EC 1.1.1.215) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ghrB / P37666 glyoxylate reductase (EC 1.1.1.79; EC 1.1.1.215) from Escherichia coli (strain K12) (see 4 papers)
GHRB_ECOLI / P37666 Glyoxylate/hydroxypyruvate reductase B; 2-ketoaldonate reductase; 2-ketogluconate reductase; 2KR; EC 1.1.1.79; EC 1.1.1.81; EC 1.1.1.215 from Escherichia coli (strain K12) (see 2 papers)
ghrB / GB|AAC76577.2 glyoxylate/hydroxypyruvate reductase B; EC 1.1.1.215; EC 1.1.1.79; EC 1.1.1.81 from Escherichia coli K12 (see 6 papers)
29% identity, 74% coverage of query (75.5 bits)
1hl3A Ctbp/bars in ternary complex with NAD(h) and pidlskk peptide
31% identity, 70% coverage of query (74.7 bits)
1hkuA Ctbp/bars: a dual-function protein involved in transcription corepression and golgi membrane fission
31% identity, 70% coverage of query (74.7 bits)
8atiA / P56545 Human ctbp2(31-364) in complex with rai2 peptide(315-322)
30% identity, 70% coverage of query (74.3 bits)
Q9Z564 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Streptomyces coelicolor (see paper)
28% identity, 83% coverage of query (74.3 bits)
4lcjA Ctbp2 in complex with substrate mtob
30% identity, 70% coverage of query (74.3 bits)
O66939 D-lactate dehydrogenase (EC 1.1.1.28) from Aquifex aeolicus (see paper)
3kb6B / O66939 Crystal structure of d-lactate dehydrogenase from aquifex aeolicus complexed with NAD and lactic acid (see paper)
25% identity, 94% coverage of query (73.9 bits)
6cdfA / Q13363 Human ctbp1 (28-378) (see paper)
30% identity, 70% coverage of query (73.6 bits)
CTBP1_RAT / Q9Z2F5 C-terminal-binding protein 1; CtBP1; 50 kDa BFA-dependent ADP-ribosylation substrate; BARS-50; C-terminal-binding protein 3; CtBP3; EC 1.1.1.- from Rattus norvegicus (Rat) (see 6 papers)
31% identity, 70% coverage of query (73.6 bits)
CTBP2_MOUSE / P56546 C-terminal-binding protein 2; CtBP2 from Mus musculus (Mouse) (see 4 papers)
30% identity, 70% coverage of query (73.6 bits)
CTBP2_RAT / Q9EQH5 C-terminal-binding protein 2; CtBP2 from Rattus norvegicus (Rat) (see paper)
30% identity, 70% coverage of query (73.6 bits)
4lceA Ctbp1 in complex with substrate mtob
30% identity, 70% coverage of query (73.6 bits)
6v89A Human ctbp1 (28-375) in complex with amp
30% identity, 70% coverage of query (73.6 bits)
4u6sA Ctbp1 in complex with substrate phenylpyruvate
30% identity, 70% coverage of query (73.6 bits)
4u6qA Ctbp1 bound to inhibitor 2-(hydroxyimino)-3-phenylpropanoic acid
30% identity, 70% coverage of query (73.6 bits)
CTBP1_MOUSE / O88712 C-terminal-binding protein 1; CtBP1; EC 1.1.1.- from Mus musculus (Mouse) (see 11 papers)
31% identity, 70% coverage of query (73.2 bits)
CTBP2_HUMAN / P56545 C-terminal-binding protein 2; CtBP2 from Homo sapiens (Human) (see 5 papers)
30% identity, 70% coverage of query (73.2 bits)
CTBP2_XENLA / Q9W758 C-terminal-binding protein 2; CtBP2; C-terminal-binding protein B; TCF-3 corepressor CtBP; XCtBP from Xenopus laevis (African clawed frog) (see paper)
29% identity, 77% coverage of query (72.4 bits)
CTBP1 / Q13363 C-terminal-binding protein 1 (EC 1.1.1.428) from Homo sapiens (see 22 papers)
CTBP1_HUMAN / Q13363 C-terminal-binding protein 1; CtBP1; EC 1.1.1.- from Homo sapiens (Human) (see 24 papers)
30% identity, 70% coverage of query (72.4 bits)
CTBP2_BOVIN / Q0VCQ1 C-terminal-binding protein 2; CtBP2 from Bos taurus (Bovine) (see paper)
29% identity, 70% coverage of query (71.2 bits)
slcC / Q1QWN6 S-sulfolactate dehydrogenase subunit (EC 1.1.1.310) from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
SLCC_CHRSD / Q1QWN6 (S)-sulfolactate dehydrogenase; (2S)-3-sulfolactate dehydrogenase; (S)-sulfolactate oxidoreductase; EC 1.1.1.310 from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
28% identity, 74% coverage of query (70.1 bits)
Q8U3Y2 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Pyrococcus furiosus (see paper)
25% identity, 86% coverage of query (68.6 bits)
5aovA / Q8U3Y2 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate (see paper)
25% identity, 86% coverage of query (68.2 bits)
HPR_BLAHS / C0CMQ8 Hydroxypyruvate reductase; EC 1.1.1.81 from Blautia hydrogenotrophica (strain DSM 10507 / JCM 14656 / S5a33) (Ruminococcus hydrogenotrophicus) (see paper)
25% identity, 77% coverage of query (67.0 bits)
U3RH61 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Acanthamoeba castellanii (see paper)
27% identity, 90% coverage of query (66.6 bits)
5dt9A / Q9KQ92 Crystal structure of a putative d-erythronate-4-phosphate dehydrogenase from vibrio cholerae
30% identity, 89% coverage of query (59.7 bits)
6t9wB / G8NTI5 Crystal structure of formate dehydrogenase fdh2 d222a/q223r enzyme from granulicella mallensis mp5actx8 in complex with NADP and azide.
24% identity, 86% coverage of query (55.5 bits)
8bxxAA Formate dehydrogenase
24% identity, 86% coverage of query (54.7 bits)
7arzA / A9SQZ2 Ternary complex of NAD-dependent formate dehydrogenase from physcomitrium patens
25% identity, 74% coverage of query (54.3 bits)
FDH1_YEASC / N1P3Y5 Formate dehydrogenase 1; FDH 1; NAD-dependent formate dehydrogenase 1; EC 1.17.1.9 from Saccharomyces cerevisiae (strain CEN.PK113-7D) (Baker's yeast) (see paper)
FDH1_YEAST / Q08911 Formate dehydrogenase 1; FDH; NAD-dependent formate dehydrogenase; EC 1.17.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
22% identity, 75% coverage of query (43.1 bits)
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Lawrence Berkeley National Laboratory