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Searching for up to 100 curated homologs for WP_086510825.1 NCBI__GCF_002151265.1:WP_086510825.1 (745 a.a.)

Found high-coverage hits (≥70%) to 21 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

V5VCI0 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Acinetobacter baumannii (see paper)
    77% identity, 99% coverage of query (1218 bits)

5z16B / V5VCI0 A novel dimeric isocitrate dehydrogenase from acinetobacter baumannii
    77% identity, 99% coverage of query (1216 bits)

IDH2_MYCTU / O53611 Isocitrate dehydrogenase [NADP] 2; ICD-2; IDH 2; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
O53611 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Mycobacterium tuberculosis (see paper)
    75% identity, 99% coverage of query (1183 bits)

5kvuA / O53611 Crystal structure of isocitrate dehydrogenase-2 in complex with NADP(+) from mycobacterium tuberculosis
    75% identity, 99% coverage of query (1176 bits)

IDH2_PSYS3 / A0A5A4WIZ7 Isocitrate dehydrogenase [NADP] 2; IDH 2; EC 1.1.1.42 from Psychrobacter sp. (strain 13A) (see paper)
    75% identity, 99% coverage of query (1175 bits)

4zdaA / A0QSZ3 Crystal structure of isocitrate dehydrogenase in complex with isocitrate and mn from m. Smegmatis
    75% identity, 99% coverage of query (1159 bits)

6g3uA / Q9I0L4 Structure of pseudomonas aeruginosa isocitrate dehydrogenase, idh (see paper)
    67% identity, 99% coverage of query (1061 bits)

1itwA / P16100 Crystal structure of the monomeric isocitrate dehydrogenase in complex with isocitrate and mn (see paper)
    66% identity, 99% coverage of query (1042 bits)

icd / P16100 isocitrate dehydrogenase (NADP-dependent) (EC 1.1.1.42) from Azotobacter vinelandii (see 5 papers)
IDH_AZOVI / P16100 Isocitrate dehydrogenase [NADP]; IDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Azotobacter vinelandii (see 3 papers)
    66% identity, 99% coverage of query (1040 bits)

1j1wA Crystal structure of the monomeric isocitrate dehydrogenase in complex with NADP+
    67% identity, 99% coverage of query (1040 bits)

IDH2_COLMA / P41561 Isocitrate dehydrogenase [NADP] 2; IDH-II; IDP-2; NADP(+)-specific ICDH 2; Oxalosuccinate decarboxylase 2; EC 1.1.1.42 from Colwellia maris (see paper)
icd / BAA03134.2 isocitrate dehydrogenase isozyme IDH-II from Colwellia maris (see paper)
    64% identity, 99% coverage of query (1011 bits)

Q1XIQ9 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Colwellia psychrerythraea (see paper)
    64% identity, 99% coverage of query (1010 bits)

idh / Q8L0X8 isocitrate dehydrogenase (EC 1.1.1.42) from Chlorobium limicola (see 3 papers)
    64% identity, 99% coverage of query (990 bits)

A0A0E3SSZ6 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Methanococcoides methylutens (see paper)
    61% identity, 99% coverage of query (951 bits)

B2ZAA4 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Streptomyces lividans (see paper)
    60% identity, 99% coverage of query (929 bits)

2b0tA / P50216 Structure of monomeric NADP isocitrate dehydrogenase (see paper)
    60% identity, 98% coverage of query (892 bits)

IDH_CORGL / P50216 Isocitrate dehydrogenase [NADP]; ICD; IDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 3 papers)
P50216 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Corynebacterium glutamicum (see paper)
    60% identity, 98% coverage of query (892 bits)

3mbcA Crystal structure of monomeric isocitrate dehydrogenase from corynebacterium glutamicum in complex with NADP
    60% identity, 98% coverage of query (892 bits)

7y1uA / A0A7M1LFL5 Crystal structure of isocitrate dehydrogenase from campylobacter corcagiensis
    53% identity, 98% coverage of query (794 bits)

J4X756 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Campylobacter sp. (see paper)
    49% identity, 99% coverage of query (733 bits)

A0A0M4S9Q1 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Campylobacter curvus (see paper)
    49% identity, 99% coverage of query (732 bits)

Build an alignment

Build an alignment for WP_086510825.1 and 21 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory