Searching for up to 100 curated homologs for WP_089302251.1 NCBI__GCF_900188115.1:WP_089302251.1 (433 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q8NT73 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Corynebacterium glutamicum (see paper)
61% identity, 97% coverage of query (530 bits)
hemL / BAA21914.1 glutamate 1-semialdehyde 2,1-aminomutase from Propionibacterium freudenreichii (see 2 papers)
53% identity, 98% coverage of query (423 bits)
3bs8A / P30949 Crystal structure of glutamate 1-semialdehyde aminotransferase complexed with pyridoxamine-5'-phosphate from bacillus subtilis (see paper)
49% identity, 99% coverage of query (419 bits)
P30949 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Bacillus subtilis (see paper)
hemL / AAA22515.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus subtilis (see 2 papers)
49% identity, 99% coverage of query (419 bits)
hemL / P0CL07 glutamate-1-semialdehyde 2,1-aminomutase subunit (EC 5.4.3.8) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
52% identity, 94% coverage of query (414 bits)
Gsa / b0154 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
hemL / P23893 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli (strain K12) (see 19 papers)
GSA_ECOLI / P23893 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Escherichia coli (strain K12) (see 3 papers)
51% identity, 98% coverage of query (412 bits)
hemL / CAD48149.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus megaterium (see paper)
49% identity, 97% coverage of query (405 bits)
3k28A / Q81LD0 Crystal structure of a glutamate-1-semialdehyde aminotransferase from bacillus anthracis with bound pyridoxal 5'phosphate
50% identity, 94% coverage of query (405 bits)
P24630 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Synechococcus sp. (see 2 papers)
50% identity, 98% coverage of query (402 bits)
6w80A / B2FT35 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from stenotrophomonas maltophilia k279a in complex with plp
52% identity, 95% coverage of query (402 bits)
GSA2_ARATH / Q42522 Glutamate-1-semialdehyde 2,1-aminomutase 2, chloroplastic; GSA 2; Glutamate-1-semialdehyde aminotransferase 2; GSA-AT 2; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
48% identity, 97% coverage of query (399 bits)
2gsaB Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
49% identity, 98% coverage of query (399 bits)
2gsaA Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
49% identity, 98% coverage of query (399 bits)
3fq7A / P24630 Gabaculine complex of gsam (see paper)
49% identity, 98% coverage of query (398 bits)
3usfA Crystal structure of dava-4
49% identity, 98% coverage of query (398 bits)
2hp2A Inter-subunit signaling in gsam
49% identity, 98% coverage of query (398 bits)
2hp1A Inter-subunit signaling in gsam
49% identity, 98% coverage of query (398 bits)
2hozA Inter-subunit signaling in gsam
49% identity, 98% coverage of query (398 bits)
3fqaA Gabaculien complex of gabaculine resistant gsam version
49% identity, 98% coverage of query (397 bits)
GSA1 / P42799 glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
GSA1_ARATH / P42799 Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic; AtGSA1; GSA 1; Glutamate-1-semialdehyde aminotransferase 1; GSA-AT 1; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
P42799 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
48% identity, 98% coverage of query (395 bits)
5i92F / P48247 Crystal structure of glutamate-1-semialdehyde 2,1- aminomutase (gsa) from pseudomonas aeruginosa
50% identity, 98% coverage of query (395 bits)
5hdmA / P42799 Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase (see paper)
48% identity, 98% coverage of query (394 bits)
5hdmB Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase
48% identity, 98% coverage of query (394 bits)
2e7uA / Q5SJS4 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from thermus thermophilus hb8
50% identity, 97% coverage of query (392 bits)
3usfB / Q31QJ2 Crystal structure of dava-4
45% identity, 98% coverage of query (352 bits)
2hp1B Inter-subunit signaling in gsam
45% identity, 98% coverage of query (347 bits)
2zsmA / Q9Y9I9 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from aeropyrum pernix, hexagonal form
46% identity, 95% coverage of query (333 bits)
GSA_SACS2 / Q980U5 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q980U5 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Saccharolobus solfataricus (see paper)
39% identity, 94% coverage of query (285 bits)
2cfbA / Q8DLK8 Glutamate-1-semialdehyde 2,1-aminomutase from thermosynechococcus elongatus (see paper)
41% identity, 87% coverage of query (273 bits)
6k8hB / D1C218 Crystal structure of an omega-transaminase from sphaerobacter thermophilus (see paper)
34% identity, 97% coverage of query (216 bits)
D1C218 beta-alanine-pyruvate transaminase (EC 2.6.1.18) from Sphaerobacter thermophilus (see paper)
34% identity, 97% coverage of query (215 bits)
4zm4B / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
36% identity, 95% coverage of query (202 bits)
4zm4D / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
35% identity, 92% coverage of query (192 bits)
6ssdA Transaminase with plp bound (see paper)
33% identity, 90% coverage of query (179 bits)
6ssgA Transaminase with dcs bound
33% identity, 90% coverage of query (179 bits)
6ssfA Transaminase with lcs bound
33% identity, 90% coverage of query (179 bits)
6sseA Transaminase with pmp bound
33% identity, 90% coverage of query (179 bits)
4aoaA Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from variovorax paradoxus
35% identity, 91% coverage of query (178 bits)
BFAT_VARPD / H8WR05 Beta-phenylalanine transaminase; Aromatic beta-amino acid aminotransferase; Beta-phenylalanine aminotransferase; VpAT; EC 2.6.1.- from Variovorax paradoxus (see paper)
H8WR05 tyrosine transaminase (EC 2.6.1.5) from Variovorax paradoxus (see paper)
35% identity, 91% coverage of query (177 bits)
4ao9A / H8WR05 Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from variovorax paradoxus (see paper)
35% identity, 91% coverage of query (177 bits)
2ykuA / A3EYF7 Structural determinants of the beta-selectivity of a bacterial aminotransferase (see paper)
31% identity, 91% coverage of query (159 bits)
2ykyA Structural determinants of the beta-selectivity of a bacterial aminotransferase
31% identity, 91% coverage of query (159 bits)
2ykxA Structural determinants of the beta-selectivity of a bacterial aminotransferase
31% identity, 91% coverage of query (159 bits)
2ykvA Structural determinants of the beta-selectivity of a bacterial aminotransferase
31% identity, 91% coverage of query (159 bits)
4ao4A Structural determinants of the beta-selectivity of a bacterial aminotransferase
31% identity, 91% coverage of query (159 bits)
MYCA_BACIU / Q9R9J1 Mycosubtilin synthase subunit A; EC 2.3.1.- from Bacillus subtilis (see paper)
33% identity, 73% coverage of query (155 bits)
6kfuA / Q9R9J1 A acp-amt fusion protein of hybrid polyketide/non-ribosomal peptide synthetase
32% identity, 73% coverage of query (150 bits)
6kfrA Amino-transferase (amt) domain - arg complex of hybrid polyketide/non- ribosomal peptide synthetase
33% identity, 73% coverage of query (150 bits)
Build an alignment for WP_089302251.1 and 48 homologs with ≥ 30% identity
Or download the sequences
KAT_CLOAI / B0VH76 3-aminobutyryl-CoA aminotransferase; HemL-like protein; EC 2.6.1.111 from Cloacimonas acidaminovorans (strain Evry) (see paper)
B0VH76 3-aminobutanoyl-CoA transaminase (EC 2.6.1.111) from Candidatus Cloacimonas acidaminovorans (see paper)
29% identity, 91% coverage of query (148 bits)
YC7B_SCHPO / O94492 Uncharacterized aminotransferase C417.11c; EC 2.6.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 72% coverage of query (144 bits)
mxcL / Q9F631 myxocheline aldehyde aminotransferase from Stigmatella aurantiaca (see 2 papers)
27% identity, 91% coverage of query (132 bits)
gdnH / K4JEW9 guadinomine polyketide synthase module 4 from Streptomyces sp. K01-0509 (see paper)
31% identity, 88% coverage of query (129 bits)
F7Y223 amino-acid racemase (EC 5.1.1.10); 2-aminohexano-6-lactam racemase (EC 5.1.1.15) from Mesorhizobium opportunistum (see paper)
32% identity, 73% coverage of query (125 bits)
lysJ / Q4JAP8 [amino group carrier protein]-C-terminal-L-glutamyl-γ-L-lysine aminotransferase (EC 2.6.1.118; EC 2.6.1.124) from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see 2 papers)
29% identity, 76% coverage of query (123 bits)
LMRAC_THEKO / Q5JGG6 Leucine/methionine racemase; Leu/Met racemase; EC 5.1.1.-; EC 5.1.1.2 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
28% identity, 95% coverage of query (122 bits)
BT3758 N-succinylornithine aminotransferase (EC 2.6.1.81) from Bacteroides thetaiotaomicron VPI-5482
29% identity, 76% coverage of query (120 bits)
A6UKD1 amino-acid racemase (EC 5.1.1.10); 2-aminohexano-6-lactam racemase (EC 5.1.1.15) from Sinorhizobium medicae (see paper)
29% identity, 77% coverage of query (119 bits)
AT2L1_HUMAN / Q8TBG4 Ethanolamine-phosphate phospho-lyase; Alanine--glyoxylate aminotransferase 2-like 1; EC 4.2.3.2 from Homo sapiens (Human) (see paper)
29% identity, 73% coverage of query (117 bits)
GabT / b2662 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655 (see 29 papers)
gabT / P22256 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli (strain K12) (see 28 papers)
GABT_ECOLI / P22256 4-aminobutyrate aminotransferase GabT; 5-aminovalerate transaminase; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT; EC 2.6.1.19; EC 2.6.1.48 from Escherichia coli (strain K12) (see 6 papers)
30% identity, 85% coverage of query (115 bits)
1sffA Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate
30% identity, 85% coverage of query (115 bits)
1sf2A / P22256 Structure of e. Coli gamma-aminobutyrate aminotransferase (see paper)
30% identity, 85% coverage of query (115 bits)
1szkA The structure of gamma-aminobutyrate aminotransferase mutant: e211s
30% identity, 85% coverage of query (115 bits)
7lonA Ornithine aminotransferase (oat) cocrystallized with its inactivator - (1s,3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
27% identity, 84% coverage of query (114 bits)
7lomC Ornithine aminotransferase (oat) soaked with its inactivator - (1s, 3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
27% identity, 84% coverage of query (114 bits)
7lomA Ornithine aminotransferase (oat) soaked with its inactivator - (1s, 3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
27% identity, 84% coverage of query (114 bits)
OAT / P04181 Ornithine aminotransferase (EC 2.6.1.13) from Homo sapiens (see 3 papers)
OAT_HUMAN / P04181 Ornithine aminotransferase, mitochondrial; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Homo sapiens (Human) (see 8 papers)
27% identity, 84% coverage of query (113 bits)
3q8nC / A0QQ04 Crystal structure of 4-aminobutyrate transaminase from mycobacterium smegmatis (see paper)
33% identity, 71% coverage of query (113 bits)
8v9mA Human ornithine aminotransferase cocrystallized with its inhibitor, (r)-3-amino-5,5-difluorocyclohex-1-ene-1-carboxylic acid.
27% identity, 84% coverage of query (113 bits)
7tedA Human ornithine aminotransferase cocrystallized with its inhibitor, (s,e)-3-amino-4-(fluoromethylene)cyclopent-1-ene-1-carboxylate
27% identity, 84% coverage of query (113 bits)
7ta1A Human ornithine aminotransferase (hoat) soaked with gamma-aminobutyric acid
27% identity, 84% coverage of query (113 bits)
7lnmB Ornithine aminotransferase (oat) cocrystallized with its inactivator - (1s,3s)-3-amino-4-(difluoromethylene)cyclopentene-1-carboxylic acid
27% identity, 84% coverage of query (113 bits)
7lk1A Ornithine aminotransferase (oat) with its potent inhibitor - (s)-3- amino-4,4-difluorocyclopent-1-enecarboxylic acid (ss-1-148) - 1 hour soaking
27% identity, 84% coverage of query (113 bits)
6v8cA Design, synthesis, and mechanism of fluorine-substituted cyclohexene analogues of gama-aminobutyric acid (gaba) as selective ornithine aminotransferase inactivators
27% identity, 84% coverage of query (113 bits)
6oiaA (1s,3s)-3-amino-4-(perfluoropropan-2-ylidene)cyclopentane-1-carboxylic acid hydrochloride, a potent inhibitor of ornithine aminotransferase
27% identity, 84% coverage of query (113 bits)
5vwoA Ornithine aminotransferase inactivated by (1r,3s,4s)-3-amino-4- fluorocyclopentane-1-carboxylic acid (fcp)
27% identity, 84% coverage of query (113 bits)
2oatA Ornithine aminotransferase complexed with 5-fluoromethylornithine
27% identity, 84% coverage of query (113 bits)
8ez1B Human ornithine aminotransferase (hoat) co-crystallized with its inactivator 3-amino-4-fluorocyclopentenecarboxylic acid
27% identity, 84% coverage of query (112 bits)
8ez1A Human ornithine aminotransferase (hoat) co-crystallized with its inactivator 3-amino-4-fluorocyclopentenecarboxylic acid
27% identity, 84% coverage of query (112 bits)
7tfpC Human ornithine aminotransferase cocrystallized with its inhibitor, (1s,3s)-3-amino-4-(difluoromethylene)cyclopentane-1-carboxylic acid.
27% identity, 84% coverage of query (112 bits)
7lk0A Ornithine aminotransferase (oat) cocrystallized with its potent inhibitor - (s)-3-amino-4,4-difluorocyclopent-1-enecarboxylic acid (ss-1-148)
27% identity, 84% coverage of query (112 bits)
7jx9A The crystal structure of human ornithine aminotransferase with an intermediate bound during inactivation by (1s,3s)-3-amino-4- (hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic acid.
27% identity, 84% coverage of query (112 bits)
6v8dA Design, synthesis, and mechanism of fluorine-substituted cyclohexene analogues of gama-aminobutyric acid (gaba) as selective ornithine aminotransferase inactivators
27% identity, 84% coverage of query (112 bits)
2canA Human ornithine aminotransferase complexed with l-canaline
27% identity, 84% coverage of query (112 bits)
1gbnB Human ornithine aminotransferase complexed with the neurotoxin gabaculine
27% identity, 84% coverage of query (112 bits)
1gbnA Human ornithine aminotransferase complexed with the neurotoxin gabaculine
27% identity, 84% coverage of query (112 bits)
7ta0A Human ornithine aminotransferase (hoat) soaked with 5-aminovaleric acid
27% identity, 84% coverage of query (112 bits)
2byjA / P04181 Ornithine aminotransferase mutant y85i (see paper)
27% identity, 84% coverage of query (110 bits)
2eh6A / O66442 Crystal structure of acetylornithine aminotransferase from aquifex aeolicus vf5
29% identity, 73% coverage of query (110 bits)
O66442 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Aquifex aeolicus (strain VF5)
29% identity, 73% coverage of query (110 bits)
6hbvA / D2D3B2 Structure of plp internal aldimine form of sphingopyxis sp. Mta144 fumi protein
27% identity, 83% coverage of query (109 bits)
6torB / Q8TBG4 Human o-phosphoethanolamine phospho-lyase (see paper)
28% identity, 72% coverage of query (107 bits)
GoaG / b1302 4-aminobutyrate aminotransferase PuuE (EC 2.6.1.19; EC 2.6.1.48) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
puuE / P50457 4-aminobutyrate aminotransferase PuuE (EC 2.6.1.19; EC 2.6.1.48) from Escherichia coli (strain K12) (see 11 papers)
PUUE_ECOLI / P50457 4-aminobutyrate aminotransferase PuuE; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; EC 2.6.1.19 from Escherichia coli (strain K12) (see 2 papers)
puuE / BAD88710.1 gamma-aminobutyrate aminotransferase from Escherichia coli K-12 (see paper)
28% identity, 88% coverage of query (107 bits)
7lldB Crystal structure of genb4 in complex with external aldimine of plp- sisomicin
31% identity, 79% coverage of query (104 bits)
7lleA Crystal structure of genb4 in complex with plp
31% identity, 79% coverage of query (104 bits)
7lldA / Q6QVT7 Crystal structure of genb4 in complex with external aldimine of plp- sisomicin
31% identity, 79% coverage of query (104 bits)
2ordA / Q9X2A5 Crystal structure of acetylornithine aminotransferase (ec 2.6.1.11) (acoat) (tm1785) from thermotoga maritima at 1.40 a resolution
29% identity, 76% coverage of query (103 bits)
Q9X2A5 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
29% identity, 76% coverage of query (103 bits)
4atqF / A1R958 Gaba-transaminase a1r958 in complex with external aldimine plp-gaba adduct (see paper)
32% identity, 76% coverage of query (102 bits)
ASRAC_PYRHO / O58478 Alanine/serine racemase; ASR; Ala/Ser racemase; EC 5.1.1.-; EC 5.1.1.1 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
28% identity, 73% coverage of query (102 bits)
7vo1A Structure of aminotransferase-substrate complex
30% identity, 71% coverage of query (101 bits)
Or start over
Lawrence Berkeley National Laboratory