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Searching for up to 100 curated homologs for WP_090440953.1 NCBI__GCF_900100495.1:WP_090440953.1 (454 a.a.)

Found high-coverage hits (≥70%) to 33 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO356_09645 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N2C3
    82% identity, 100% coverage of query (767 bits)

Pf6N2E2_3808 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N2E2
    82% identity, 100% coverage of query (766 bits)

Pf1N1B4_1591 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N1B4
    80% identity, 100% coverage of query (760 bits)

hutF / Q4KJP1 formiminoglutamate deiminase subunit (EC 3.5.3.13) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    80% identity, 100% coverage of query (759 bits)

PfGW456L13_330 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens GW456-L13
    80% identity, 100% coverage of query (756 bits)

AO353_12235 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N2E3
    80% identity, 100% coverage of query (756 bits)

PS417_01705 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas simiae WCS417
    76% identity, 100% coverage of query (736 bits)

HUTF_PSEAE / Q9HU77 Formimidoylglutamate deiminase; Formiminoglutamate deiminase; N-formimino-L-glutamate deiminase; N-formimino-L-glutamate iminohydrolase; EC 3.5.3.13 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9HU77 formimidoylglutamate deiminase (EC 3.5.3.13); formimidoylglutamase (EC 3.5.3.8) from Pseudomonas aeruginosa (see paper)
    78% identity, 100% coverage of query (695 bits)

4rdvB / Q9HU77 The structure of n-formimino-l-glutamate iminohydrolase from pseudomonas aeruginosa complexed with n-formimino-l-aspartate
    78% identity, 99% coverage of query (691 bits)

3mduA The structure of n-formimino-l-glutamate iminohydrolase from pseudomonas aeruginosa complexed with n-guanidino-l-glutamate
    78% identity, 99% coverage of query (689 bits)

SMc00673 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Sinorhizobium meliloti 1021
    57% identity, 98% coverage of query (489 bits)

Ac3H11_2549 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Acidovorax sp. GW101-3H11
    54% identity, 95% coverage of query (431 bits)

4f0lB / Q2YIL4 Crystal structure of amidohydrolase from brucella melitensis
    49% identity, 99% coverage of query (412 bits)

PGA1_c36360 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Phaeobacter inhibens BS107
    47% identity, 100% coverage of query (379 bits)

Build an alignment

Build an alignment for WP_090440953.1 and 14 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PA0142 / Q9I6Z0 8-oxoguanine deaminase monomer (EC 3.5.4.32) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
OXODE_PSEAE / Q9I6Z0 8-oxoguanine deaminase; EC 3.5.4.32 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I6Z0 8-oxoguanine deaminase (EC 3.5.4.32) from Pseudomonas aeruginosa (see paper)
    27% identity, 86% coverage of query (98.2 bits)

4dzhA / Q8P8H1 Crystal structure of an adenosine deaminase from xanthomonas campestris (target nysgrc-200456) with bound zn
    26% identity, 86% coverage of query (82.4 bits)

3lnpA / D3KFX9 Crystal structure of amidohydrolase family protein olei01672_1_465 from oleispira antarctica (see paper)
    26% identity, 85% coverage of query (76.6 bits)

4f0rA / Q7NZ90 Crystal structure of an adenosine deaminase homolog from chromobacterium violaceum (target nysgrc-019589) bound zn and 5'- methylthioadenosine (unproductive complex)
    26% identity, 87% coverage of query (76.3 bits)

4f0sA Crystal structure of an adenosine deaminase homolog from chromobacterium violaceum (target nysgrc-019589) with bound inosine.
    26% identity, 87% coverage of query (76.3 bits)

8is4A Structure of an isocytosine specific deaminase vcz in complexed with 5-fu (see paper)
    22% identity, 89% coverage of query (68.6 bits)

3hpaA Crystal structure of an amidohydrolase gi:44264246 from an evironmental sample of sargasso sea (see paper)
    25% identity, 89% coverage of query (67.4 bits)

IXPDE_UNKP / P0CI72 Isoxanthopterin deaminase; EC 3.5.4.11 from Unknown prokaryotic organism (see paper)
P0CI72 pterin deaminase (EC 3.5.4.11) from unidentified prokaryotic organism (see paper)
    24% identity, 89% coverage of query (61.2 bits)

trzN / Q8VS01 triazine hydrolase subunit (EC 3.8.1.8) from Nocardioides sp. C190 (see paper)
    25% identity, 75% coverage of query (60.5 bits)

5hmdA / A1RCJ9 Crystal structure of triazine hydrolase variant (y215h/e241q) (see paper)
    25% identity, 75% coverage of query (59.7 bits)

trzN / A1RCJ9 triazine hydrolase (EC 3.8.1.8) from Paenarthrobacter aurescens (strain TC1) (see 3 papers)
    25% identity, 75% coverage of query (59.3 bits)

3lscA Crystal structure of the mutant e241q of atrazine chlorohydrolase trzn from arthrobacter aurescens tc1 complexed with zinc and atraton
    24% identity, 75% coverage of query (58.9 bits)

3lsbA Crystal structure of the mutant e241q of atrazine chlorohydrolase trzn from arthrobacter aurescens tc1 complexed with zinc and ametrin
    24% identity, 75% coverage of query (58.9 bits)

T1Z209 atrazine chlorohydrolase (EC 3.8.1.8) from Arthrobacter sp. DNS10 (see paper)
    24% identity, 75% coverage of query (58.2 bits)

A1RCX5 hydroxydechloroatrazine ethylaminohydrolase (EC 3.5.4.43) from Paenarthrobacter aurescens (see paper)
    24% identity, 89% coverage of query (55.5 bits)

atzB / P95442 hydroxyatrazine ethylaminohydrolase monomer (EC 3.5.4.43) from Pseudomonas sp. (strain ADP) (see 2 papers)
ATZB_PSESD / P95442 Hydroxydechloroatrazine ethylaminohydrolase; Hydroxyatrazine hydrolase; EC 3.5.4.43 from Pseudomonas sp. (strain ADP) (see paper)
    24% identity, 89% coverage of query (55.1 bits)

2i9uA / Q97MB6 Crystal structure of guanine deaminase from c. Acetobutylicum with bound guanine in the active site
    20% identity, 84% coverage of query (54.7 bits)

2plmA Crystal structure of the protein tm0936 from thermotoga maritima complexed with zn and s-inosylhomocysteine
    24% identity, 89% coverage of query (51.2 bits)

1p1mA / Q9X034 Structure of thermotoga maritima amidohydrolase tm0936 bound to ni and methionine
    24% identity, 89% coverage of query (51.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory