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Searching for up to 100 curated homologs for WP_090447976.1 NCBI__GCF_900100495.1:WP_090447976.1 (339 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

rdmC / Q54528 aclacinomycin methylesterase (EC 3.1.1.95) from Streptomyces purpurascens (see 2 papers)
RDMC_STREF / Q54528 Aclacinomycin methylesterase RdmC; EC 3.1.1.95 from Streptomyces purpurascens (see 3 papers)
Q54528 aclacinomycin methylesterase (EC 3.1.1.95) from Streptomyces purpurascens (see paper)
    31% identity, 85% coverage of query (119 bits)

1q0rA / Q54528 Crystal structure of aclacinomycin methylesterase (rdmc) with bound product analogue, 10-decarboxymethylaclacinomycin t (dcmat) (see paper)
    31% identity, 85% coverage of query (119 bits)

1q0zA Crystal structure of aclacinomycin methylesterase (rdmc) with bound product analogue, 10-decarboxymethylaclacinomycin a (dcma)
    31% identity, 85% coverage of query (119 bits)

dauP / Q55217 rhodomycinone D methylesterase from Streptomyces sp. (strain C5) (see 2 papers)
DNRP_STRS5 / Q55217 Rhodomycin D methylesterase DauP; 10-carbomethoxy-13-deoxycarminomycin esterase; 4-O-methylrhodomycin D methylesterase; EC 3.1.1.- from Streptomyces sp. (strain C5) (see paper)
    31% identity, 86% coverage of query (110 bits)

bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
    33% identity, 79% coverage of query (107 bits)

dnrP / Q54809 rhodomycinone D methyl-esterase from Streptomyces peucetius (see 3 papers)
    30% identity, 86% coverage of query (105 bits)

6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
    31% identity, 86% coverage of query (96.7 bits)

6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
    31% identity, 86% coverage of query (94.4 bits)

6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
    31% identity, 86% coverage of query (93.6 bits)

Build an alignment

Build an alignment for WP_090447976.1 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

AO353_17230 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas fluorescens FW300-N2E3
    29% identity, 76% coverage of query (84.3 bits)

O73957 carboxylesterase (EC 3.1.1.1) from Sulfolobus acidocaldarius (see paper)
    29% identity, 78% coverage of query (78.6 bits)

pcaD / Q88N36 subunit of 3-oxoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 5 papers)
Q88N36 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Pseudomonas putida (see paper)
    27% identity, 85% coverage of query (77.8 bits)

pcaL / AAC38246.1 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase from Rhodococcus opacus (see paper)
    31% identity, 76% coverage of query (73.9 bits)

BPHL_HUMAN / Q86WA6 Valacyclovir hydrolase; VACVase; Valacyclovirase; Biphenyl hydrolase-like protein; Biphenyl hydrolase-related protein; Bph-rp; Breast epithelial mucin-associated antigen; MCNAA; EC 3.1.-.- from Homo sapiens (Human) (see 2 papers)
    26% identity, 84% coverage of query (64.3 bits)

2ocgA / Q86WA6 Crystal structure of human valacyclovir hydrolase (see paper)
    28% identity, 83% coverage of query (63.9 bits)

2ociA Crystal structure of valacyclovir hydrolase complexed with a product analogue
    28% identity, 83% coverage of query (63.9 bits)

catD / AAC46435.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 8 papers)
    25% identity, 77% coverage of query (62.4 bits)

Q5Y152 poly(3-hydroxyoctanoate) depolymerase (EC 3.1.1.76) from Pseudomonas putida (see paper)
    28% identity, 76% coverage of query (61.2 bits)

2xuaH / Q13KT2 Crystal structure of the enol-lactonase from burkholderia xenovorans lb400 (see paper)
    27% identity, 71% coverage of query (55.1 bits)

Q13KT2 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Paraburkholderia xenovorans (see 2 papers)
    27% identity, 71% coverage of query (55.1 bits)

pcaD / AAF34270.1 beta-ketoadipate enol-lactone hydrolase from Agrobacterium tumefaciens (see 2 papers)
    27% identity, 78% coverage of query (54.7 bits)

pcaD / AAC37150.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 11 papers)
    25% identity, 76% coverage of query (54.7 bits)

catD / BAA75208.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see paper)
catD / BAC82535.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see 3 papers)
    26% identity, 79% coverage of query (53.1 bits)

cpoF / PDB|1A8S non-heme chloroperoxidase; EC 1.11.1.10 from Pseudomonas fluorescens (see 2 papers)
    25% identity, 76% coverage of query (51.2 bits)

Q5FMT1 prolyl aminopeptidase (EC 3.4.11.5) from Lactobacillus acidophilus (see paper)
    22% identity, 81% coverage of query (45.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory