Searching for up to 100 curated homologs for WP_092057054.1 NCBI__GCF_900111775.1:WP_092057054.1 (318 a.a.)
Found high-coverage hits (≥70%) to 75 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
rokA / Q5GBH5 glucokinase / N-acetylglucosamine kinase / mannokinase (EC 2.7.1.7; EC 2.7.1.1; EC 2.7.1.59) from Bacteroides fragilis (see 2 papers)
37% identity, 97% coverage of query (179 bits)
Q8RDE9 glucokinase (EC 2.7.1.2) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
35% identity, 98% coverage of query (172 bits)
Q8R8N4 ADP-specific glucose/glucosamine kinase (EC 2.7.1.147) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
35% identity, 97% coverage of query (160 bits)
3vgkB / B1VZT1 Crystal structure of a rok family glucokinase from streptomyces griseus (see paper)
37% identity, 96% coverage of query (143 bits)
3vglA Crystal structure of a rok family glucokinase from streptomyces griseus in complex with glucose and amppnp
37% identity, 96% coverage of query (143 bits)
B1VZT1 glucokinase (EC 2.7.1.2) from Streptomyces griseus (see 2 papers)
37% identity, 96% coverage of query (142 bits)
2qm1B / Q830J4 Crystal structure of glucokinase from enterococcus faecalis
33% identity, 98% coverage of query (140 bits)
glkA / CAA62003.1 glucokinase from Renibacterium salmoninarum (see 2 papers)
39% identity, 97% coverage of query (140 bits)
1z05A / Q9KQJ1 Crystal structure of the rok family transcriptional regulator, homolog of e.Coli mlc protein.
34% identity, 82% coverage of query (140 bits)
GLK_STRCO / P0A4E1 Glucokinase; Glucose kinase; ORF 3; EC 2.7.1.2 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
P0A4E1 glucokinase (EC 2.7.1.2) from Streptomyces coelicolor (see paper)
glkA glucokinase; EC 2.7.1.2 from Streptomyces coelicolor (see 2 papers)
37% identity, 96% coverage of query (139 bits)
Build an alignment for WP_092057054.1 and 10 homologs with ≥ 30% identity
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NanR / VIMSS6110394 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides plebeius DSM 17135
28% identity, 97% coverage of query (134 bits)
XylR / VIMSS38296 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus subtilis subsp. subtilis str. 168
28% identity, 97% coverage of query (134 bits)
O31392 glucokinase (EC 2.7.1.2) from Priestia megaterium (see paper)
glk glucokinase; EC 2.7.1.2 from Bacillus megaterium (see paper)
glk / CAA03848.1 glucose kinase from Bacillus megaterium (see paper)
35% identity, 96% coverage of query (133 bits)
glk / Q9X1I0 glucokinase subunit (EC 2.7.1.1) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
GLK_THEMA / Q9X1I0 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
35% identity, 96% coverage of query (131 bits)
glk / Q8DVE8 glucokinase subunit (EC 2.7.1.1) from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see paper)
33% identity, 98% coverage of query (129 bits)
XylR / VIMSS6926953 XylR regulator of Xylose utilization, effector Xylose (repressor) from Paenibacillus sp. JDR-2
31% identity, 99% coverage of query (129 bits)
glcK / P54495 glucokinase (EC 2.7.1.1) from Bacillus subtilis (strain 168) (see paper)
GLK_BACSU / P54495 Glucokinase; Glucose kinase; EC 2.7.1.2 from Bacillus subtilis (strain 168) (see paper)
P54495 glucokinase (EC 2.7.1.2) from Bacillus subtilis (see paper)
34% identity, 95% coverage of query (128 bits)
XylR / P16557 Transcription factor XylR (repressor) from Bacillus subtilis 168 (see 2 papers)
30% identity, 77% coverage of query (128 bits)
glcK / GI|1303865 glucokinase; EC 2.7.1.2 from Bacillus subtilis (see paper)
34% identity, 95% coverage of query (125 bits)
NagC / VIMSS3566654 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Aeromonas salmonicida subsp. salmonicida A449
31% identity, 81% coverage of query (125 bits)
XylR / VIMSS854293 XylR regulator of Xylose utilization, effector Xylose (repressor) from Geobacillus kaustophilus HTA426
31% identity, 96% coverage of query (125 bits)
NagC / VIMSS1972937 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Psychromonas ingrahamii 37
30% identity, 75% coverage of query (122 bits)
NagC / VIMSS548778 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (activator/repressor) from Photorhabdus luminescens TTO1
30% identity, 83% coverage of query (121 bits)
CA265_RS11300 N-acetylglucosamine kinase (EC 2.7.1.59) from Pedobacter sp. GW460-11-11-14-LB5
29% identity, 96% coverage of query (121 bits)
NagC / VIMSS4630820 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Moritella sp. PE36
30% identity, 77% coverage of query (120 bits)
NagC / VIMSS339340 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (activator/repressor) from Vibrio parahaemolyticus RIMD 2210633
30% identity, 85% coverage of query (118 bits)
NanR / VIMSS3720738 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides vulgatus ATCC 8482
25% identity, 97% coverage of query (117 bits)
Mlc / b1594 DNA-binding transcriptional repressor Mlc from Escherichia coli K-12 substr. MG1655 (see 15 papers)
MLC_ECOLI / P50456 DNA-binding transcriptional repressor Mlc; Making large colonies protein; Membrane linked control from Escherichia coli (strain K12) (see 15 papers)
Mlc / P50456 Transcription factor Mlc (repressor) from Escherichia coli K12 MG1655 (see 4 papers)
mlc / RF|NP_416111.1 protein mlc from Escherichia coli K12 (see 7 papers)
28% identity, 84% coverage of query (115 bits)
1z6rA / P50456 Crystal structure of mlc from escherichia coli (see paper)
28% identity, 84% coverage of query (114 bits)
NanR / VIMSS6257414 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides eggerthii DSM 20697
26% identity, 96% coverage of query (114 bits)
NagC / VIMSS79758 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Pasteurella multocida subsp. multocida str. Pm70
29% identity, 81% coverage of query (114 bits)
4db3A / Q8D9M7 1.95 angstrom resolution crystal structure of n-acetyl-d-glucosamine kinase from vibrio vulnificus.
29% identity, 97% coverage of query (112 bits)
XylR / VIMSS730014 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus licheniformis DSM 13
29% identity, 88% coverage of query (112 bits)
NagC / VIMSS2859304 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Psychromonas sp. CNPT3
29% identity, 74% coverage of query (112 bits)
XylR / VIMSS279908 XylR regulator of Xylose utilization, effector Xylose (repressor) from Oceanobacillus iheyensis HTE831
28% identity, 97% coverage of query (112 bits)
7p7wBBB / Q12306,R8APY9 7p7wBBB
31% identity, 96% coverage of query (112 bits)
7p9lAAA Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase
31% identity, 96% coverage of query (112 bits)
7p9pAAA Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase
31% identity, 96% coverage of query (112 bits)
NagC / b0676 DNA-binding transcriptional dual regulator NagC from Escherichia coli K-12 substr. MG1655 (see 14 papers)
NAGC_ECOLI / P0AF20 N-acetylglucosamine repressor from Escherichia coli (strain K12) (see paper)
NagC / P0AF20 Transcription factor NagC (activator/repressor) from Escherichia coli K12 MG1655 (see 3 papers)
nagC / SP|P0AF20 N-acetylglucosamine repressor from Escherichia coli K12 (see paper)
31% identity, 85% coverage of query (110 bits)
Mak / b0394 fructokinase (EC 2.7.1.7; EC 2.7.1.4) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
mak / P23917 fructokinase (EC 2.7.1.7; EC 2.7.1.4) from Escherichia coli (strain K12) (see 8 papers)
MAK_ECOLI / P23917 Fructokinase; D-fructose kinase; Manno(fructo)kinase; EC 2.7.1.4 from Escherichia coli (strain K12) (see 2 papers)
30% identity, 96% coverage of query (110 bits)
XylR / P70928_BACLI Transcription factor XylR (repressor) from Bacillus licheniformis Gibson 46 (see paper)
29% identity, 88% coverage of query (110 bits)
XylR / VIMSS822024 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus clausii KSM-K16
27% identity, 82% coverage of query (107 bits)
YcfX / b1119 N-acetyl-D-glucosamine kinase (EC 2.7.1.59) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
nagK / P75959 N-acetyl-D-glucosamine kinase (EC 2.7.1.59) from Escherichia coli (strain K12) (see 6 papers)
NAGK_ECOLI / P75959 N-acetyl-D-glucosamine kinase; GlcNAc kinase; EC 2.7.1.59 from Escherichia coli (strain K12) (see 2 papers)
nagK / GB|ABB62126.1 N-acetyl-D-glucosamine kinase; EC 2.7.1.59 from Escherichia coli K12 (see 5 papers)
32% identity, 96% coverage of query (107 bits)
5f7qE / Q8YAF1 Rok repressor lmo0178 from listeria monocytogenes bound to operator (see paper)
31% identity, 77% coverage of query (107 bits)
NagC / VIMSS2773935 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Reinekea sp. MED297
31% identity, 72% coverage of query (106 bits)
XylR / VIMSS3426742 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus pumilus SAFR-032
27% identity, 97% coverage of query (104 bits)
SMc03109 Mannokinase (EC 2.7.1.7) from Sinorhizobium meliloti 1021
30% identity, 96% coverage of query (104 bits)
agaK / A0KYQ6 N-acetylgalactosamine kinase from Shewanella sp. (strain ANA-3) (see paper)
AGAK_SHESA / A0KYQ6 N-acetylgalactosamine kinase AgaK; GalNAc kinase; N-acetylglucosamine kinase; GlcNAc kinase; EC 2.7.1.-; EC 2.7.1.59 from Shewanella sp. (strain ANA-3) (see paper)
31% identity, 96% coverage of query (104 bits)
5f7rA Rok repressor lmo0178 from listeria monocytogenes bound to inducer
32% identity, 77% coverage of query (103 bits)
H6UH58 glucokinase (EC 2.7.1.2) from Staphylococcus aureus (see paper)
29% identity, 98% coverage of query (97.4 bits)
6jdbA / Q4QP43 Crystal structure of n-acetyl mannosmaine kinase in complex with mannac-6p and adp from haemophilus influenzae
27% identity, 81% coverage of query (96.3 bits)
2yi1A Crystal structure of n-acetylmannosamine kinase in complex with n- acetyl mannosamine 6-phosphate and adp.
30% identity, 87% coverage of query (92.0 bits)
2yhyA Structure of n-acetylmannosamine kinase in complex with n- acetylmannosamine and adp
30% identity, 87% coverage of query (92.0 bits)
GLK_PYRCJ / A3MUZ0 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) (see paper)
A3MUZ0 glucokinase (EC 2.7.1.2) from Pyrobaculum calidifontis (see paper)
32% identity, 96% coverage of query (91.3 bits)
2yhwA / Q9Y223 High-resolution crystal structures of n-acetylmannosamine kinase: insights about substrate specificity, activity and inhibitor modelling. (see paper)
31% identity, 87% coverage of query (90.9 bits)
GLCNE_HUMAN / Q9Y223 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; EC 3.2.1.183; EC 2.7.1.60 from Homo sapiens (Human) (see 24 papers)
Q9Y223 N-acylmannosamine kinase (EC 2.7.1.60); UDP-N-acetylglucosamine 2-epimerase (hydrolysing) (EC 3.2.1.183); UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) (EC 5.1.3.14) from Homo sapiens (see 18 papers)
33% identity, 82% coverage of query (88.6 bits)
Q8RDN7 N-acylmannosamine kinase (EC 2.7.1.60) from Fusobacterium nucleatum subsp. nucleatum (see paper)
27% identity, 96% coverage of query (88.6 bits)
6jdhA Crystal structure of n-acetyl mannosmaine kinase from pasteurella multocida
27% identity, 96% coverage of query (88.2 bits)
6jdoA Crystal structure of n-acetyl mannosmaine kinase with amp-pnp from pasteurella multocida
27% identity, 96% coverage of query (88.2 bits)
Sama_1405 glucokinase (EC 2.7.1.2) from Shewanella amazonensis SB2B
30% identity, 98% coverage of query (87.8 bits)
CelQ / VIMSS2059852 CelQ regulator of Cellobiose utilization, effector Cellobiose-6-phosphate (repressor) from Streptococcus sanguinis SK36
25% identity, 73% coverage of query (86.3 bits)
Gne / O35826 bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase subunit (EC 2.7.1.60; EC 3.2.1.183) from Rattus norvegicus (see paper)
GLCNE_RAT / O35826 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; EC 3.2.1.183; EC 2.7.1.60 from Rattus norvegicus (Rat) (see 5 papers)
32% identity, 82% coverage of query (86.3 bits)
GLCNE_MOUSE / Q91WG8 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; EC 3.2.1.183; EC 2.7.1.60 from Mus musculus (Mouse) (see 3 papers)
Q91WG8 UDP-N-acetylglucosamine 2-epimerase (hydrolysing) (EC 3.2.1.183) from Mus musculus (see paper)
32% identity, 82% coverage of query (86.3 bits)
NAGK_SALTY / Q8ZPZ9 N-acetyl-D-glucosamine kinase; GlcNAc kinase; EC 2.7.1.59 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
32% identity, 96% coverage of query (85.1 bits)
2ap1A / Q8ZPZ9 Crystal structure of the putative regulatory protein
32% identity, 96% coverage of query (85.1 bits)
GLCNE_CRIGR / Q7TQ49 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; EC 3.2.1.183; EC 2.7.1.60 from Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (see paper)
31% identity, 88% coverage of query (84.7 bits)
3eo3A / Q9Y223 Crystal structure of the n-acetylmannosamine kinase domain of human gne protein (see paper)
30% identity, 87% coverage of query (83.6 bits)
Q5SLJ4 hexokinase (EC 2.7.1.1) from Thermus thermophilus (see paper)
33% identity, 80% coverage of query (83.6 bits)
Q5RLG0 hexokinase (EC 2.7.1.1) from Thermus caldophilus (see paper)
34% identity, 80% coverage of query (83.2 bits)
3vovB / Q5SLJ4 Crystal structure of rok hexokinase from thermus thermophilus (see paper)
34% identity, 80% coverage of query (80.9 bits)
YhcI / b3222 N-acetylmannosamine kinase (EC 2.7.1.60) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
nanK / P45425 N-acetylmannosamine kinase (EC 2.7.1.60) from Escherichia coli (strain K12) (see 5 papers)
NANK_ECOLI / P45425 N-acetylmannosamine kinase; ManNAc kinase; N-acetyl-D-mannosamine kinase; EC 2.7.1.60 from Escherichia coli (strain K12) (see 3 papers)
30% identity, 82% coverage of query (75.1 bits)
2aa4A / P45425 Crystal structure of escherichia coli putative n-acetylmannosamine kinase, new york structural genomics consortium
30% identity, 82% coverage of query (75.1 bits)
3lm9A Crystal structure of fructokinase with adp and fructose bound in the active site
26% identity, 96% coverage of query (66.6 bits)
1xc3A / O05510 Structure of a putative fructokinase from bacillus subtilis (see paper)
26% identity, 96% coverage of query (66.2 bits)
BGLK_KLEPN / Q93LQ8 Beta-glucoside kinase; EC 2.7.1.85 from Klebsiella pneumoniae (see paper)
27% identity, 95% coverage of query (66.2 bits)
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Lawrence Berkeley National Laboratory