Searching for up to 100 curated homologs for WP_092057244.1 NCBI__GCF_900111775.1:WP_092057244.1 (133 a.a.)
Found high-coverage hits (≥70%) to 32 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
MCE_PYRHO / O58010 Methylmalonyl-CoA epimerase; DL-methylmalonyl-CoA racemase; EC 5.1.99.1 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see 2 papers)
56% identity, 98% coverage of query (145 bits)
3oa4A / Q9KCV1 Crystal structure of hypothetical protein bh1468 from bacillus halodurans c-125
48% identity, 95% coverage of query (130 bits)
mcee / A9WGS0 methylmalonyl-CoA epimerase (EC 5.1.99.1) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
48% identity, 98% coverage of query (109 bits)
Msed_0639 / A4YEG2 methylmalonyl-CoA epimerase monomer (EC 5.1.99.1) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 2 papers)
A4YEG2 methylmalonyl-CoA epimerase (EC 5.1.99.1) from Metallosphaera sedula (see paper)
40% identity, 95% coverage of query (107 bits)
MCEE / Q96PE7 methylmalonyl CoA epimerase (EC 5.1.99.1) from Homo sapiens (see 4 papers)
MCEE_HUMAN / Q96PE7 Methylmalonyl-CoA epimerase, mitochondrial; DL-methylmalonyl-CoA racemase; EC 5.1.99.1 from Homo sapiens (Human) (see 2 papers)
42% identity, 95% coverage of query (104 bits)
6wf6A Streptomyces coelicolor methylmalonyl-coa epimerase
45% identity, 94% coverage of query (104 bits)
6wfhA Streptomyces coelicolor methylmalonyl-coa epimerase substrate complex
45% identity, 94% coverage of query (104 bits)
6wf7A / Q9L2C2 Methylmalonyl-coa epimerase in complex with methylmalonyl-coa and nh4+ (see paper)
45% identity, 94% coverage of query (103 bits)
6xbqA Streptomyces coelicolor methylmalonyl-coa epimerase in complex with carboxy-carba(dethia)-coa
45% identity, 94% coverage of query (103 bits)
6wfiA Methylmalonyl-coa epimerase in complex with 2-nitronate-propionyl-coa
45% identity, 94% coverage of query (103 bits)
6xbtA Streptomyces coelicolor methylmalonyl-coa epimerase (q60a) in complex with 2-nitronate-propionyl-coa
45% identity, 94% coverage of query (103 bits)
EPI_CERS4 / Q3IZP4 Ethylmalonyl-CoA/methylmalonyl-CoA epimerase; EC 5.1.99.-; EC 5.1.99.1 from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter sphaeroides) (see paper)
42% identity, 98% coverage of query (100 bits)
6qh4C / Q96PE7 Crystal structure of human methylmalonyl-coa epimerase (mcee) p.Arg143cys variant
41% identity, 98% coverage of query (97.8 bits)
K7SKA8 methylmalonyl-CoA epimerase (EC 5.1.99.1) from Acidipropionibacterium acidipropionici (see paper)
35% identity, 96% coverage of query (87.8 bits)
epi / CAJ91089.1 methylmalonyl-CoA epimerase from Sorangium cellulosum (see paper)
38% identity, 96% coverage of query (82.4 bits)
GI:18042134 / Q8VQN0 methylmalonyl CoA epimerase subunit (EC 5.1.99.1) from Propionibacterium freudenreichii subsp. shermanii (see 4 papers)
33% identity, 95% coverage of query (72.4 bits)
Build an alignment for WP_092057244.1 and 16 homologs with ≥ 30% identity
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Q8RCQ6 methylmalonyl-CoA epimerase (EC 5.1.99.1) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
29% identity, 84% coverage of query (62.4 bits)
Q97H22 lactoylglutathione lyase (EC 4.4.1.5) from Clostridium acetobutylicum (see paper)
33% identity, 89% coverage of query (54.7 bits)
2qh0A / Q97H22 Crystal structure of a glyoxalase from clostridium acetobutylicum
33% identity, 89% coverage of query (54.7 bits)
P0A0T3 lactoylglutathione lyase (EC 4.4.1.5) from Neisseria meningitidis (see paper)
30% identity, 83% coverage of query (52.0 bits)
3zgjB / Q9Z4X7 S221m v223f y359a mutant of 4-hydroxymandelate synthase from streptomyces coelicolor (see paper)
32% identity, 83% coverage of query (50.8 bits)
Q9I5L8 lactoylglutathione lyase (EC 4.4.1.5) from Pseudomonas aeruginosa (see paper)
31% identity, 97% coverage of query (48.9 bits)
4mttA / Q9I5L8 Ni- and zn-bound gloa2 at low resolution (see paper)
31% identity, 97% coverage of query (48.5 bits)
1fa5A / P0AC81 Crystal structure of the zn(ii)-bound glyoxalase i of escherichia coli (see paper)
29% identity, 83% coverage of query (46.2 bits)
GloA / b1651 glyoxalase I (EC 4.4.1.5) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
gloA / P0AC81 lactoylglutathione lyase (EC 4.4.1.5) from Escherichia coli (strain K12) (see 19 papers)
LGUL_ECOLI / P0AC81 Lactoylglutathione lyase; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase; EC 4.4.1.5 from Escherichia coli (strain K12) (see 6 papers)
P0AC81 lactoylglutathione lyase (EC 4.4.1.5) from Escherichia coli (see 3 papers)
gloA / RF|NP_416168.1 lactoylglutathione lyase; EC 4.4.1.5 from Shigella flexneri (see 5 papers)
29% identity, 83% coverage of query (46.2 bits)
1fa6A Crystal structure of the co(ii)-bound glyoxalase i of escherichia coli
29% identity, 83% coverage of query (46.2 bits)
Dsui_0512 Methylmalonyl-CoA epimerase (EC 5.1.99.1) from Dechlorosoma suillum PS
28% identity, 95% coverage of query (45.1 bits)
7yvvA / A0A7H8HIR4 Acmp1, r-4-hydroxymandelate synthase
30% identity, 73% coverage of query (44.7 bits)
LGUC_ARATH / Q8W593 Probable lactoylglutathione lyase, chloroplastic; Glyoxalase I; EC 4.4.1.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
26% identity, 84% coverage of query (43.9 bits)
5hmqD / Q88JU3 Xylose isomerase-like tim barrel/4-hydroxyphenylpyruvate dioxygenase fusion protein
31% identity, 74% coverage of query (42.0 bits)
2r5vA / O52791 Hydroxymandelate synthase crystal structure (see paper)
27% identity, 79% coverage of query (41.2 bits)
DSD_PSEPK / Q88JU3 3-dehydroshikimate dehydratase; DSD; EC 4.2.1.118 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
30% identity, 74% coverage of query (40.8 bits)
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