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Searching for up to 100 curated homologs for WP_092344162.1 NCBI__GCF_900107645.1:WP_092344162.1 (433 a.a.)

Found high-coverage hits (≥70%) to 32 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q97MC0 aspartate kinase (EC 2.7.2.4) from Clostridium acetobutylicum (see paper)
    41% identity, 98% coverage of query (324 bits)

3tviE / Q97MC0 Crystal structure of clostridium acetobutylicum aspartate kinase (caak): an important allosteric enzyme for industrial amino acids production (see paper)
    41% identity, 98% coverage of query (323 bits)

3tviA Crystal structure of clostridium acetobutylicum aspartate kinase (caak): an important allosteric enzyme for industrial amino acids production
    41% identity, 98% coverage of query (309 bits)

yclM / P94417 aspartate kinase III (EC 2.7.2.4) from Bacillus subtilis (strain 168) (see 4 papers)
AK3_BACSU / P94417 Aspartokinase 3; Aspartate kinase 3; Aspartokinase III; EC 2.7.2.4 from Bacillus subtilis (strain 168) (see paper)
    34% identity, 96% coverage of query (235 bits)

Build an alignment

Build an alignment for WP_092344162.1 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) from Echinicola vietnamensis KMM 6221, DSM 17526
    28% identity, 99% coverage of query (154 bits)

CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) from Pedobacter sp. GW460-11-11-14-LB5
    28% identity, 97% coverage of query (147 bits)

AK2_ARATH / O23653 Aspartokinase 2, chloroplastic; Aspartate kinase 2; EC 2.7.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
O23653 aspartate kinase (EC 2.7.2.4) from Arabidopsis thaliana (see 2 papers)
    28% identity, 98% coverage of query (139 bits)

ThrD / b0002 fused aspartate kinase/homoserine dehydrogenase 1 (EC 2.7.2.4; EC 1.1.1.3) from Escherichia coli K-12 substr. MG1655 (see paper)
thrA / P00561 fused aspartate kinase/homoserine dehydrogenase 1 (EC 2.7.2.4; EC 1.1.1.3) from Escherichia coli (strain K12) (see 33 papers)
P00561 homoserine dehydrogenase (EC 1.1.1.3); aspartate kinase (EC 2.7.2.4) from Escherichia coli (see paper)
    26% identity, 98% coverage of query (139 bits)

BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) from Bacteroides thetaiotaomicron VPI-5482
    29% identity, 99% coverage of query (136 bits)

3c1mC / Q57991 Cyrstal structure of threonine-sensitive aspartokinase from methanococcus jannaschii with mgamp-pnp and l-aspartate (see paper)
    28% identity, 98% coverage of query (136 bits)

Q57991 aspartate kinase (EC 2.7.2.4) from Methanocaldococcus jannaschii (see 2 papers)
    27% identity, 98% coverage of query (135 bits)

2hmfA Structure of a threonine sensitive aspartokinase from methanococcus jannaschii complexed with mg-adp and aspartate
    28% identity, 98% coverage of query (135 bits)

3c1nA Crystal structure of allosteric inhibition threonine-sensitive aspartokinase from methanococcus jannaschii with l-threonine
    28% identity, 98% coverage of query (133 bits)

Q5JK18 aspartate kinase (EC 2.7.2.4) from Oryza sativa Japonica Group (see paper)
    28% identity, 98% coverage of query (132 bits)

thrA1A2 / CAA43212.1 aspartate kinase from Serratia marcescens (see paper)
    28% identity, 94% coverage of query (130 bits)

AK3 / Q9S702 aspartate kinase (EC 2.7.2.4) from Arabidopsis thaliana (see paper)
AK3_ARATH / Q9S702 Aspartokinase 3, chloroplastic; Aspartate kinase 3; EC 2.7.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9S702 aspartate kinase (EC 2.7.2.4) from Arabidopsis thaliana (see 2 papers)
    27% identity, 98% coverage of query (130 bits)

2cdqA / Q9LYU8 Crystal structure of arabidopsis thaliana aspartate kinase complexed with lysine and s- adenosylmethionine (see paper)
    27% identity, 98% coverage of query (128 bits)

AK1_ARATH / Q9LYU8 Aspartokinase 1, chloroplastic; Aspartate kinase 1; EC 2.7.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9LYU8 aspartate kinase (EC 2.7.2.4) from Arabidopsis thaliana (see 2 papers)
    27% identity, 98% coverage of query (128 bits)

ABZR86_RS19560 aspartate kinase / diaminopimelate decarboxylase (EC 4.1.1.20; EC 2.7.2.4) from Dyella japonica UNC79MFTsu3.2
    26% identity, 96% coverage of query (118 bits)

AKH1_ARATH / Q9SA18 Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic; AK-HD 1; AK-HSDH 1; Beta-aspartyl phosphate homoserine 1; EC 2.7.2.4; EC 1.1.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    27% identity, 99% coverage of query (117 bits)

FUB3_GIBM7 / W7MS01 Aspartate kinase FUB3; Fusaric acid biosynthesis protein 3; EC 2.7.2.4 from Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) (see 10 papers)
    29% identity, 76% coverage of query (116 bits)

O60163 Probable aspartokinase; Aspartate kinase; EC 2.7.2.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    29% identity, 76% coverage of query (116 bits)

AKH2_ARATH / O81852 Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic; AK-HD 2; AK-HSDH 2; Beta-aspartyl phosphate homoserine 2; EC 2.7.2.4; EC 1.1.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    26% identity, 99% coverage of query (113 bits)

FUB3_FUSO4 / A0A0D2YG09 Aspartate kinase FUB3; Fusaric acid biosynthesis protein 3; EC 2.7.2.4 from Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) (Fusarium vascular wilt of tomato) (see 8 papers)
    28% identity, 76% coverage of query (112 bits)

FUB3_GIBF5 / S0DVT6 Aspartate kinase FUB3; Fusaric acid biosynthesis protein 3; EC 2.7.2.4 from Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae and foot rot disease fungus) (Fusarium fujikuroi) (see 9 papers)
    28% identity, 76% coverage of query (111 bits)

2j0wA / P08660 Crystal structure of e. Coli aspartokinase iii in complex with aspartate and adp (r-state) (see paper)
    26% identity, 99% coverage of query (110 bits)

Apk / b4024 aspartate kinase III (EC 2.7.2.4) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lysC / P08660 aspartate kinase III (EC 2.7.2.4) from Escherichia coli (strain K12) (see 27 papers)
AK3_ECOLI / P08660 Lysine-sensitive aspartokinase 3; Aspartate kinase III; AKIII; Lysine-sensitive aspartokinase III; EC 2.7.2.4 from Escherichia coli (strain K12) (see 2 papers)
P08660 aspartate kinase (EC 2.7.2.4) from Escherichia coli (see paper)
    26% identity, 99% coverage of query (110 bits)

2j0xA Crystal structure of e. Coli aspartokinase iii in complex with lysine and aspartate (t-state)
    26% identity, 99% coverage of query (110 bits)

AK_YEAST / P10869 Aspartokinase; Aspartate kinase; EC 2.7.2.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P10869 aspartate kinase (EC 2.7.2.4) from Saccharomyces cerevisiae (see paper)
    28% identity, 79% coverage of query (108 bits)

AAA16972.1 aspartokinase-homoserine dehydrogenase, partial from Daucus carota (see paper)
    26% identity, 99% coverage of query (105 bits)

O63067 homoserine dehydrogenase (EC 1.1.1.3) from Glycine max (see paper)
    26% identity, 99% coverage of query (105 bits)

AK_PSEPK / Q88EI9 Aspartate kinase; Aspartokinase; EC 2.7.2.4 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
    28% identity, 95% coverage of query (94.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory