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Searching for up to 100 curated homologs for WP_092344299.1 NCBI__GCF_900107645.1:WP_092344299.1 (359 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

fabX / O25465 decanoate oxidase (EC 1.3.3.6; EC 5.3.3.14) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 2 papers)
    39% identity, 96% coverage of query (250 bits)

7e1qA / A0A0B2E3F3 Crystal structure of dehydrogenase/isomerase fabx from helicobacter pylori (see paper)
    39% identity, 96% coverage of query (249 bits)

7e1sC Crystal structure of dehydrogenase/isomerase fabx from helicobacter pylori in complex with octanoyl-acp
    39% identity, 96% coverage of query (249 bits)

7e1sA Crystal structure of dehydrogenase/isomerase fabx from helicobacter pylori in complex with octanoyl-acp
    39% identity, 96% coverage of query (249 bits)

7e1rA Crystal structure of dehydrogenase/isomerase fabx from helicobacter pylori in complex with holo-acp
    39% identity, 96% coverage of query (249 bits)

Build an alignment

Build an alignment for WP_092344299.1 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

fabK / D4YGY7 enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.9) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
    28% identity, 97% coverage of query (92.8 bits)

7l00C / A0A031WIF2 Crystal structure of c. Difficile enoyl-acyl carrier protein reductase (fabk) in complex with an inhibitor
    26% identity, 96% coverage of query (89.7 bits)

Q8DR17 enoyl-[acyl-carrier-protein] reductase (NADH) (EC 1.3.1.9) from Streptococcus pneumoniae (see 2 papers)
    28% identity, 75% coverage of query (80.9 bits)

fabK / Q9FBC5 enoyl-[acyl-carrier-protein] reductase (NADH) monomer (EC 1.3.1.9) from Streptococcus pneumoniae (see 8 papers)
fabK / AAF98273.1 trans-2-enoyl-ACP reductase II from Streptococcus pneumoniae (see paper)
    28% identity, 75% coverage of query (79.7 bits)

2z6iB / Q9FBC5 Crystal structure of s. Pneumoniae enoyl-acyl carrier protein reductase (fabk) (see paper)
    28% identity, 75% coverage of query (79.7 bits)

5gvhA / Q9WZQ7 Structure of fabk from thermotoga maritima (see paper)
    26% identity, 96% coverage of query (74.3 bits)

2z6jA Crystal structure of s. Pneumoniae enoyl-acyl carrier protein reductase (fabk) in complex with an inhibitor
    29% identity, 75% coverage of query (71.6 bits)

ipdC / P71847 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA dehydrogenase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
IPDC_MYCTU / P71847 (3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA dehydrogenase; 5OH-HIC-CoA dehydrogenase; EC 1.3.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    27% identity, 77% coverage of query (59.7 bits)

fabK / Q7MAW0 enoyl-[acyl-carrier-protein] reductase II (NADPH) monomer (EC 1.3.1.10) from Porphyromonas gingivalis (strain ATCC BAA-308 / W83) (see 3 papers)
Q7MAW0 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) (EC 1.3.1.10); enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific) (EC 1.3.1.39) from Porphyromonas gingivalis (see 2 papers)
4iqlA / Q7MAW0 Crystal structure of porphyromonas gingivalis enoyl-acp reductase ii (fabk) with cofactors NADPH and fmn (see paper)
    28% identity, 94% coverage of query (59.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory