Searching for up to 100 curated homologs for WP_102999320.1 NCBI__GCF_002893965.1:WP_102999320.1 (261 a.a.)
Found high-coverage hits (≥70%) to 33 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
hsaE / Q0S817 2-hydroxyhexa-2,4-dienoate hydratase (EC 4.2.1.132) from Rhodococcus jostii (strain RHA1) (see paper)
87% identity, 100% coverage of query (460 bits)
hsaE / I6XHH5 2-hydroxyhexa-2,4-dienoate hydratase (EC 4.2.1.132) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
70% identity, 100% coverage of query (359 bits)
cnbE / Q38M38 2-oxopent-4-enoate hydratase (EC 4.2.1.80) from Comamonas testosteroni CNB-1 (see paper)
44% identity, 96% coverage of query (209 bits)
dmpE / CAA43225.1 2-hydroxypent-2,4-dienoate hydratase from Pseudomonas sp. CF600 (see paper)
43% identity, 97% coverage of query (202 bits)
nahL / BAE92170.1 2-oxypent-4-enoate hydratase NahL from Pseudomonas putida (see 2 papers)
42% identity, 97% coverage of query (201 bits)
2eb5A Crystal structure of hpcg complexed with oxalate
41% identity, 100% coverage of query (198 bits)
bphH / CAA54034.1 2-hydroxypenta-2,4-dienoate hydratase from Paraburkholderia xenovorans LB400 (see paper)
42% identity, 99% coverage of query (197 bits)
tesE / Q83VZ5 2-hydroxyhexa-2,4-dienoate hydratase (EC 4.2.1.132) from Comamonas testosteroni (see 2 papers)
TESE_COMTE / Q83VZ5 2-hydroxyhexa-2,4-dienoate hydratase; EC 4.2.1.132 from Comamonas testosteroni (Pseudomonas testosteroni) (see 2 papers)
41% identity, 95% coverage of query (194 bits)
HPCG_ECOLX / P42270 2-oxo-hept-4-ene-1,7-dioate hydratase; OHED hydratase; EC 4.2.1.163 from Escherichia coli (see paper)
P42270 2-oxo-hept-4-ene-1,7-dioate hydratase (EC 4.2.1.163) from Escherichia coli (see 2 papers)
Q46982 2-oxo-hept-4-ene-1,7-dioate hydratase (EC 4.2.1.163) from Escherichia coli (see paper)
2eb6A / Q46982 Crystal structure of hpcg complexed with mg ion (see paper)
39% identity, 100% coverage of query (192 bits)
MHPD_COMTE / Q9S156 2-keto-4-pentenoate hydratase; 2-hydroxypentadienoic acid hydratase; EC 4.2.1.80 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
41% identity, 99% coverage of query (191 bits)
cbzJ2 / AAX50132.1 CbzJ2 from Pseudomonas putida (see paper)
40% identity, 97% coverage of query (187 bits)
carD / BAC41552.1 2-hydroxypenta-2,4-dienoate hydratase from Pseudomonas resinovorans (see 9 papers)
38% identity, 96% coverage of query (186 bits)
etbE / BAA18938.1 2-hydroxypenta-2,4-dienoate hydratase from Rhodococcus sp (see 2 papers)
40% identity, 100% coverage of query (184 bits)
MhpS / b0350 2-hydroxypentadienoate hydratase (EC 4.2.1.80) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
mhpD / P77608 2-hydroxypentadienoate hydratase (EC 4.2.1.80) from Escherichia coli (strain K12) (see 3 papers)
MHPD_ECOLI / P77608 2-keto-4-pentenoate hydratase; 2-hydroxypentadienoic acid hydratase; EC 4.2.1.80 from Escherichia coli (strain K12) (see paper)
P77608 2-oxopent-4-enoate hydratase (EC 4.2.1.80) from Escherichia coli K-12 (see paper)
38% identity, 97% coverage of query (182 bits)
dmpH / CAA43228.1 4-oxalocrotonate decarboxylase from Pseudomonas sp. CF600 (see paper)
39% identity, 96% coverage of query (178 bits)
AMNF_PSESP / Q9KWS4 2-oxopent-4-enoate hydratase; 2-keto-4-pentenoate hydratase; EC 4.2.1.80 from Pseudomonas sp. (see 2 papers)
38% identity, 97% coverage of query (177 bits)
nahK / AAX38571.1 NahK from Pseudomonas putida (see paper)
39% identity, 96% coverage of query (175 bits)
xylJ / P23107 2-oxopent-4-enoate hydratase subunit (EC 4.2.1.80) from Pseudomonas putida (see paper)
43% identity, 82% coverage of query (174 bits)
xylI / P49155 4-oxalocrotonate decarboxylase subunit (EC 4.1.1.77) from Pseudomonas putida (see 2 papers)
xylI / AAA25693.1 4-oxalocrotonate decarboxylase from Pseudomonas putida (see paper)
38% identity, 96% coverage of query (169 bits)
Q1XGK3 2-oxo-3-hexenedioate decarboxylase (EC 4.1.1.77) from Pseudomonas putida (see paper)
nahK / BAE92173.1 4-oxalocrotonate decarboxylase NahK from Pseudomonas putida (see 2 papers)
37% identity, 96% coverage of query (169 bits)
todG / Q79DA5 2-oxopent-4-enoate hydratase (EC 4.2.1.80) from Pseudomonas putida (see paper)
todG / AAA61942.1 2-hydroxypenta-2,4-dienoate hydratase from Pseudomonas putida (see paper)
38% identity, 96% coverage of query (168 bits)
5d2gA / Q1XGK3 4-oxalocrotonate decarboxylase from pseudomonas putida g7 - complexed with magnesium (see paper)
37% identity, 96% coverage of query (166 bits)
5d2kA 4-oxalocrotonate decarboxylase from pseudomonas putida g7 - complexed with magnesium and 2-oxoadipate
37% identity, 96% coverage of query (166 bits)
5d2jA 4-oxalocrotonate decarboxylase from pseudomonas putida g7 - complexed with magnesium and adipate
37% identity, 96% coverage of query (166 bits)
5d2iA 4-oxalocrotonate decarboxylase from pseudomonas putida g7 - complexed with calcium and acetate
37% identity, 96% coverage of query (166 bits)
5d2hA 4-oxalocrotonate decarboxylase from pseudomonas putida g7 - complexed with magnesium and alpha-ketoglutarate
37% identity, 96% coverage of query (166 bits)
praD / C4TP06 2-oxo-3-hexenedioate decarboxylase (EC 4.1.1.77) from Paenibacillus sp. JJ-1b (see paper)
praD / BAH79104.1 4-oxalocrotonate decarboxylase from Paenibacillus sp. JJ-1b (see paper)
37% identity, 95% coverage of query (165 bits)
B0VXM8 2-oxo-3-hexenedioate decarboxylase (EC 4.1.1.77) from Geobacillus stearothermophilus (see paper)
39% identity, 96% coverage of query (164 bits)
cmtF / Q51981 2-oxopent-4-enoate hydratase (EC 4.2.1.80) from Pseudomonas putida (see paper)
cmtF / AAB62293.1 2-hydroxypenta-2,4-dienoate hydratase from Pseudomonas putida (see 3 papers)
38% identity, 97% coverage of query (159 bits)
cnbF / Q38M37 2-oxo-3-hexenedioate decarboxylase (EC 4.1.1.77) from Comamonas testosteroni CNB-1 (see paper)
35% identity, 97% coverage of query (130 bits)
amnE / Q9KWS3 4-oxalocrotonate decarboxylase monomer (EC 4.1.1.77) from Pseudomonas sp. (see paper)
AMNE_PSESP / Q9KWS3 4-oxalocrotonate decarboxylase; EC 4.1.1.77 from Pseudomonas sp. (see 2 papers)
37% identity, 87% coverage of query (123 bits)
nbaG / Q83V28 2-oxo-3-hexenedioate decarboxylase (EC 4.1.1.77) from Pseudomonas fluorescens (see paper)
33% identity, 91% coverage of query (103 bits)
cbzJ / AAX38586.1 CbzJ from Pseudomonas putida (see paper)
31% identity, 85% coverage of query (85.9 bits)
Build an alignment for WP_102999320.1 and 33 homologs with ≥ 30% identity
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Lawrence Berkeley National Laboratory