Searching for up to 100 curated homologs for WP_110206771.1 NCBI__GCF_003194585.1:WP_110206771.1 (260 a.a.)
Found high-coverage hits (≥70%) to 79 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q0SH24 3-oxoadipate enol-lactonase (EC 3.1.1.24); 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) from Rhodococcus jostii (see paper)
45% identity, 94% coverage of query (206 bits)
pcaL / AAC38246.1 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase from Rhodococcus opacus (see paper)
45% identity, 94% coverage of query (204 bits)
catD / AAC46435.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 8 papers)
43% identity, 92% coverage of query (198 bits)
AO353_17230 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas fluorescens FW300-N2E3
43% identity, 94% coverage of query (189 bits)
pcaD / Q88N36 subunit of 3-oxoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 5 papers)
Q88N36 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Pseudomonas putida (see paper)
40% identity, 98% coverage of query (180 bits)
Q13KT2 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Paraburkholderia xenovorans (see 2 papers)
40% identity, 92% coverage of query (174 bits)
2xuaH / Q13KT2 Crystal structure of the enol-lactonase from burkholderia xenovorans lb400 (see paper)
40% identity, 92% coverage of query (173 bits)
catD / BAA75208.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see paper)
catD / BAC82535.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see 3 papers)
40% identity, 92% coverage of query (172 bits)
pcaD / AAC37150.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 11 papers)
36% identity, 91% coverage of query (161 bits)
pcaD / AAF34270.1 beta-ketoadipate enol-lactone hydrolase from Agrobacterium tumefaciens (see 2 papers)
35% identity, 87% coverage of query (140 bits)
4uhfA / A0A0M3KKY6 Structural studies of a thermophilic esterase from thermogutta terrifontis (l37a mutant with butyrate bound) (see paper)
33% identity, 89% coverage of query (112 bits)
4uhdA Structural studies of a thermophilic esterase from thermogutta terrifontis (acetate bound)
33% identity, 89% coverage of query (112 bits)
4uheA Structural studies of a thermophilic esterase from thermogutta terrifontis (malate bound)
33% identity, 89% coverage of query (112 bits)
Build an alignment for WP_110206771.1 and 13 homologs with ≥ 30% identity
Or download the sequences
bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
29% identity, 90% coverage of query (93.2 bits)
O73957 carboxylesterase (EC 3.1.1.1) from Sulfolobus acidocaldarius (see paper)
30% identity, 80% coverage of query (85.5 bits)
6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
30% identity, 83% coverage of query (76.6 bits)
6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
29% identity, 83% coverage of query (75.9 bits)
6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
29% identity, 83% coverage of query (75.1 bits)
TGND_ACIAD / Q6F9F4 (E)-2-((N-methylformamido)methylene)succinate hydrolase; MFMS hydrolase; EC 3.5.1.- from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
26% identity, 92% coverage of query (74.7 bits)
Q8KT44 carboxylesterase (EC 3.1.1.1) from Lacticaseibacillus casei (see paper)
25% identity, 92% coverage of query (69.7 bits)
YBFK_BACSU / O31452 Carboxylesterase YbfK; EC 3.1.1.1 from Bacillus subtilis (strain 168) (see paper)
27% identity, 94% coverage of query (64.7 bits)
EstN1 / K0IAM1 pimeloyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85) from Nitrososphaera gargensis (strain Ga9.2) (see paper)
24% identity, 93% coverage of query (64.3 bits)
3hi4A Switching catalysis from hydrolysis to perhydrolysis in p. Fluorescens esterase
28% identity, 86% coverage of query (62.8 bits)
3heaA The l29p/l124i mutation of pseudomonas fluorescens esterase
28% identity, 86% coverage of query (62.8 bits)
3ia2A Pseudomonas fluorescens esterase complexed to the r-enantiomer of a sulfonate transition state analog
28% identity, 86% coverage of query (62.8 bits)
ESTE_PSEFL / P22862 Arylesterase; Aryl-ester hydrolase; Carboxylic acid perhydrolase; PFE; Putative bromoperoxidase; EC 3.1.1.2; EC 1.-.-.- from Pseudomonas fluorescens (see 8 papers)
GI|951089 arylesterase; EC 1.-.-.-; EC 3.1.1.2 from Pseudomonas fluorescens (see 3 papers)
AAB60168.1 esterase from Pseudomonas fluorescens (see 2 papers)
28% identity, 86% coverage of query (62.4 bits)
4lxhA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 3- cl hopda (see paper)
26% identity, 87% coverage of query (62.4 bits)
bphD / BAA25612.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus erythropolis (see paper)
29% identity, 80% coverage of query (62.4 bits)
4lyeA Crystal structure of the s105a mutant of a c-c hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with substrate hopda
26% identity, 87% coverage of query (62.4 bits)
4lxiA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 5, 8-dif hopda
26% identity, 87% coverage of query (62.4 bits)
ABHDB_BOVIN / Q3SZ73 sn-1-specific diacylglycerol lipase ABHD11; Alpha/beta hydrolase domain-containing protein 11; Abhydrolase domain-containing protein 11; EC 3.1.1.116 from Bos taurus (Bovine) (see paper)
25% identity, 96% coverage of query (61.6 bits)
NAP_BACSU / P96688 Uncharacterized carboxylesterase nap; EC 3.1.1.1 from Bacillus subtilis (strain 168)
24% identity, 92% coverage of query (61.2 bits)
8pi1B / P22862 Bicyclic incypro pseudomonas fluorescens esterase (see paper)
28% identity, 86% coverage of query (61.2 bits)
RutD / b1009 putative aminoacrylate hydrolase RutD from Escherichia coli K-12 substr. MG1655 (see 2 papers)
RUTD_ECOLI / P75895 Putative carbamate hydrolase RutD; Aminohydrolase; EC 3.5.1.- from Escherichia coli (strain K12) (see 5 papers)
27% identity, 91% coverage of query (61.2 bits)
D0EPY0 carboxylesterase (EC 3.1.1.1) from Bacillus subtilis (see paper)
24% identity, 92% coverage of query (61.2 bits)
4ccwA / Q59248 Crystal structure of naproxen esterase (carboxylesterase np) from bacillus subtilis (see paper)
24% identity, 92% coverage of query (60.5 bits)
flnE / BAC75995.1 meta cleavage compound hydrolase from Terrabacter sp. DBF63 (see paper)
27% identity, 86% coverage of query (60.1 bits)
Q3HWU8 carboxylesterase (EC 3.1.1.1) from Pseudomonas putida (see paper)
27% identity, 75% coverage of query (57.8 bits)
AGH13449.1 hybrid C-C meta-cleavage hydrolase-carboxylesterase from Cycloclasticus zancles (see paper)
24% identity, 85% coverage of query (57.8 bits)
dauP / Q55217 rhodomycinone D methylesterase from Streptomyces sp. (strain C5) (see 2 papers)
DNRP_STRS5 / Q55217 Rhodomycin D methylesterase DauP; 10-carbomethoxy-13-deoxycarminomycin esterase; 4-O-methylrhodomycin D methylesterase; EC 3.1.1.- from Streptomyces sp. (strain C5) (see paper)
27% identity, 92% coverage of query (57.0 bits)
ABHDB_HUMAN / Q8NFV4 sn-1-specific diacylglycerol lipase ABHD11; Alpha/beta hydrolase domain-containing protein 11; Abhydrolase domain-containing protein 11; Williams-Beuren syndrome chromosomal region 21 protein; EC 3.1.1.116 from Homo sapiens (Human) (see 3 papers)
25% identity, 96% coverage of query (56.2 bits)
dnrP / Q54809 rhodomycinone D methyl-esterase from Streptomyces peucetius (see 3 papers)
25% identity, 92% coverage of query (55.5 bits)
ABHDB_MOUSE / Q8K4F5 sn-1-specific diacylglycerol lipase ABHD11; Alpha/beta hydrolase domain-containing protein 11; Abhydrolase domain-containing protein 11; Williams-Beuren syndrome chromosomal region 21 protein homolog; EC 3.1.1.116 from Mus musculus (Mouse) (see 3 papers)
27% identity, 96% coverage of query (54.7 bits)
PHAZ_PSEOL / P26495 Poly(3-hydroxyalkanoate) depolymerase; PHA depolymerase; ORF2; PHB depolymerase; EC 3.1.1.- from Pseudomonas oleovorans (see paper)
phaB / AAA25933.1 PHA-depolymerase from Pseudomonas oleovorans (see paper)
25% identity, 94% coverage of query (53.9 bits)
bpdF / AAB17100.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus sp. M5 (see paper)
26% identity, 92% coverage of query (53.1 bits)
picE / A0A1X9WE55 N-formylmaleamate deformylase (EC 3.5.1.106) from Alcaligenes faecalis (see paper)
25% identity, 85% coverage of query (52.8 bits)
5dnuA / A0A0M3PN85 Crystal structure of striga kai2-like protein in complex with karrikin (see paper)
24% identity, 90% coverage of query (52.4 bits)
rdmC / Q54528 aclacinomycin methylesterase (EC 3.1.1.95) from Streptomyces purpurascens (see 2 papers)
RDMC_STREF / Q54528 Aclacinomycin methylesterase RdmC; EC 3.1.1.95 from Streptomyces purpurascens (see 3 papers)
Q54528 aclacinomycin methylesterase (EC 3.1.1.95) from Streptomyces purpurascens (see paper)
26% identity, 81% coverage of query (52.0 bits)
1q0rA / Q54528 Crystal structure of aclacinomycin methylesterase (rdmc) with bound product analogue, 10-decarboxymethylaclacinomycin t (dcmat) (see paper)
26% identity, 81% coverage of query (52.0 bits)
1q0zA Crystal structure of aclacinomycin methylesterase (rdmc) with bound product analogue, 10-decarboxymethylaclacinomycin a (dcma)
26% identity, 81% coverage of query (52.0 bits)
8hgwA / Q2MHH5 Crystal structure of mehph in complex with mbp (see paper)
23% identity, 85% coverage of query (50.8 bits)
4ihaA Crystal structure of rice dwarf14 (d14) in complex with a gr24 hydrolysis intermediate
26% identity, 77% coverage of query (49.3 bits)
6ap8A Crystal structure of rice d14 bound to 2-(2-methyl-3-nitroanilino) benzoic acid
25% identity, 77% coverage of query (49.3 bits)
5dj5A Crystal structure of rice dwarf14 in complex with synthetic strigolactone gr24
25% identity, 77% coverage of query (49.3 bits)
5zhsA Crystal structure of osd14 in complex with covalently bound kk052
25% identity, 77% coverage of query (49.3 bits)
5zhtA Crystal structure of osd14 in complex with covalently bound kk073
25% identity, 77% coverage of query (48.9 bits)
5zhrA Crystal structure of osd14 in complex with covalently bound kk094
25% identity, 77% coverage of query (48.9 bits)
5yz7A Crystal structure of osd14 in complex with d-ring-opened 7'-carba-4bd
25% identity, 77% coverage of query (48.9 bits)
6brtA / A0A0D9Z3K8 F-box protein cth with hydrolase (see paper)
25% identity, 77% coverage of query (48.9 bits)
8y9oA Crystal structure of atkai2 in complex with kk181n1
22% identity, 90% coverage of query (48.9 bits)
4jymA / Q9SZU7 Crystal structure of kai2 in complex with 3-methyl-2h-furo[2,3- c]pyran-2-one (see paper)
22% identity, 90% coverage of query (48.9 bits)
D14_ORYSJ / Q10QA5 Strigolactone esterase D14; Protein DWARF 14; Protein DWARF 88; Protein HIGH-TILLERING DWARF 2; EC 3.1.-.- from Oryza sativa subsp. japonica (Rice) (see 11 papers)
25% identity, 77% coverage of query (48.5 bits)
KAI2_ARATH / Q9SZU7 Probable esterase KAI2; Protein DWARF-14-like; Protein D14-like; Protein HYPOSENSITIVE TO LIGHT; Protein KARRIKIN INSENSITIVE 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
22% identity, 90% coverage of query (48.5 bits)
2d0dA Crystal structure of a meta-cleavage product hydrolase (cumd) a129v mutant
23% identity, 72% coverage of query (48.1 bits)
RSBQ_BACSU / O07015 Sigma factor SigB regulation protein RsbQ from Bacillus subtilis (strain 168) (see 2 papers)
23% identity, 91% coverage of query (47.4 bits)
1iunB / P96965 Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant hexagonal (see paper)
22% identity, 72% coverage of query (47.0 bits)
1ukaA Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with (s)-2-methylbutyrate
22% identity, 72% coverage of query (47.0 bits)
1uk9A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with isovalerate
22% identity, 72% coverage of query (47.0 bits)
1uk8A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-valerate
22% identity, 72% coverage of query (47.0 bits)
1uk7A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-butyrate
22% identity, 72% coverage of query (47.0 bits)
1iupA Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant complexed with isobutyrates
22% identity, 72% coverage of query (47.0 bits)
8agpAAA Alpha/beta epoxide hydrolase
24% identity, 87% coverage of query (45.8 bits)
5ng7B Novel epoxide hydrolases belonging to the alpha/beta hydrolases superfamily in metagenomes from hot environments
24% identity, 87% coverage of query (45.8 bits)
8agsAAA / A0A1U9WZ52 8agsAAA
24% identity, 87% coverage of query (45.8 bits)
8agnAAA Alpha/beta epoxide hydrolase
24% identity, 87% coverage of query (45.4 bits)
8agmAAA Alpha/beta epoxide hydrolase
24% identity, 87% coverage of query (45.4 bits)
aamsh1 / Q988D4 2-(acetamidomethylene)succinate hydrolase monomer (EC 3.5.1.29) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see 7 papers)
AAMHY_RHILO / Q988D4 2-(acetamidomethylene)succinate hydrolase; alpha-(N-acetylaminomethylene)succinic acid amidohydrolase; AAMS amidohydrolase; EC 3.5.1.29 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099)) (see 2 papers)
Q988D4 2-(acetamidomethylene)succinate hydrolase (EC 3.5.1.29) from Mesorhizobium loti (see 2 papers)
27% identity, 82% coverage of query (45.1 bits)
4k2aC / E2RV62 Crystal structure of haloalkane dehalogenase dbea from bradyrhizobium elkani usda94 (see paper)
22% identity, 94% coverage of query (42.7 bits)
5w15D / B1YPY7 Crystal structure of an alpha/beta hydrolase fold protein from burkholderia ambifaria.
24% identity, 91% coverage of query (42.7 bits)
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Lawrence Berkeley National Laboratory