Searching for up to 100 curated homologs for WP_111605763.1 NCBI__GCF_003259225.1:WP_111605763.1 (277 a.a.)
Found high-coverage hits (≥70%) to 47 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
SM_b20327 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 2 (ThuG) from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q5 ThuG aka RB0313 aka SMB20327, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 3 papers)
74% identity, 97% coverage of query (390 bits)
Pf1N1B4_5114 sucrose ABC transporter, permease component 2 from Pseudomonas fluorescens FW300-N1B4
67% identity, 96% coverage of query (368 bits)
TC 3.A.1.1.12 / Q9AI66 PalG, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
58% identity, 93% coverage of query (312 bits)
TC 3.A.1.1.41 / G4FGN6 ABC-type transporter, integral membrane subunit, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
48% identity, 99% coverage of query (264 bits)
TC 3.A.1.1.25 / Q72H66 Maltose transport system permease protein malG aka TT_C1629, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
52% identity, 91% coverage of query (241 bits)
MALG_THELN / Q7LYX6 Trehalose/maltose transport system permease protein MalG from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 3 papers)
TC 3.A.1.1.7 / O51925 MalG aka PF1741, component of Maltose/trehalose porter (see paper)
41% identity, 94% coverage of query (196 bits)
sugB / P9WG01 ABC-type trehalose transporter integral membrane protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGB_MYCTU / P9WG01 Trehalose transport system permease protein SugB from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
TC 3.A.1.1.31 / O50453 PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGB, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 3 papers)
41% identity, 94% coverage of query (184 bits)
smoH / Q7CS31 ABC-type 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol transporter permease subunit from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
38% identity, 92% coverage of query (180 bits)
YcjP / b1312 putative ABC transporter membrane subunit YcjP from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TC 3.A.1.1.46 / P77716 Inner membrane ABC transporter permease protein YcjP, component of Probable glucoside uptake porter, YcjNOPV from Escherichia coli (strain K12)
36% identity, 100% coverage of query (162 bits)
Dshi_0549 ABC transporter for Xylitol, permease component 2 from Dinoroseobacter shibae DFL-12
34% identity, 95% coverage of query (153 bits)
DASC_STRCO / Q9K489 Diacetylchitobiose uptake system permease protein DasC from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
35% identity, 94% coverage of query (150 bits)
TC 3.A.1.1.33 / Q8KN17 Putative sugar transporter integral membrane protein, component of The N,N'-diacetylchitobiose uptake transporter, DasABC/MsiK (MsiK energizes several ABC transporters (see 3.A.1.1.23)) from Streptomyces sp. 139 (see 2 papers)
32% identity, 99% coverage of query (149 bits)
TC 3.A.1.1.18 / Q8RJU8 NgcG, component of N-Acetylglucosamine/N,N'-diacetyl chitobiose porter (NgcK (C) not identified) from Streptomyces olivaceoviridis (Streptomyces corchorusii) (see paper)
31% identity, 97% coverage of query (145 bits)
SM_b21105 ABC transporter for L-Fucose, permease component 2 from Sinorhizobium meliloti 1021
35% identity, 75% coverage of query (139 bits)
SMc02871 ABC transporter for N-Acetyl-D-glucosamine, permease protein 2 from Sinorhizobium meliloti 1021
31% identity, 96% coverage of query (133 bits)
TC 3.A.1.1.49 / O30493 MtlG, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
32% identity, 93% coverage of query (132 bits)
Build an alignment for WP_111605763.1 and 16 homologs with ≥ 30% identity
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NGCG_STRCO / O50501 Diacetylchitobiose uptake system permease protein NgcG from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
28% identity, 94% coverage of query (132 bits)
PS417_12705 ABC transporter for D-Mannitol and D-Sorbitol, permease component 1 from Pseudomonas simiae WCS417
32% identity, 93% coverage of query (131 bits)
mtlG / Q4KC55 polyol ABC-type transporter permease component MtlG from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
32% identity, 93% coverage of query (130 bits)
TC 3.A.1.1.44 / Q9KZ08 Putative maltose permease, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
29% identity, 99% coverage of query (130 bits)
SM_b21219 ABC transporter for D-Glucosamine, permease component 1 from Sinorhizobium meliloti 1021
34% identity, 96% coverage of query (129 bits)
AO356_00015 ABC transporter for D-Sorbitol, permease component 1 from Pseudomonas fluorescens FW300-N2C3
32% identity, 94% coverage of query (129 bits)
Pf6N2E2_1961 ABC transporter for D-sorbitol, permease component 2 from Pseudomonas fluorescens FW300-N2E2
32% identity, 94% coverage of query (129 bits)
Q9X2F5 ABC-type maltose transporter (subunit 1/2) (EC 7.5.2.1) from Thermotoga maritima (see paper)
TC 3.A.1.1.22 / Q9X2F5 MalG2; aka Maltose ABC transporter, permease protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
33% identity, 77% coverage of query (127 bits)
PGA1_c27950 N-Acetyl-D-glucosamine ABC transport system, permease component 2 from Phaeobacter inhibens BS107
29% identity, 97% coverage of query (125 bits)
TC 3.A.1.1.5 / O30833 SmoG, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) (see paper)
33% identity, 99% coverage of query (125 bits)
TC 3.A.1.1.6 / Q48397 CymG, component of Cyclodextrin porter from Klebsiella oxytoca (see paper)
27% identity, 96% coverage of query (124 bits)
BPHYT_RS16105 ABC transporter for D-Sorbitol, permease component 1 from Burkholderia phytofirmans PsJN
30% identity, 95% coverage of query (122 bits)
GANQ_BACSU / O07011 Galactooligosaccharides transport system permease protein GanQ from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.1.2 / O07011 Putative arabinogalactan oligomer transport system permease protein ganQ, component of The galactooligosaccharide (transports the di, tri and tetrasaccharides) uptake porter GanOPQ (GanSPQ; MalEFG) functioning with the energizing ATPase MsmX (see 3.A.1.1.26) from Bacillus subtilis (see 2 papers)
28% identity, 96% coverage of query (120 bits)
HSERO_RS17010 ABC transporter for D-sorbitol/xylitol, permease component 2 from Herbaspirillum seropedicae SmR1
30% identity, 96% coverage of query (120 bits)
TC 3.A.1.1.27 / Q8DT26 MalG, component of Maltose/Maltotriose/maltodextrin (up to 7 glucose units) transporters MalXFGK (MsmK (3.A.1.1.28) can probably substitute for MalK; Webb et al., 2008) from Streptococcus mutans (see paper)
30% identity, 100% coverage of query (119 bits)
ARAQ_BACSU / P94530 Arabinooligosaccharides transport system permease protein AraQ from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.1.34 / P94530 L-arabinose transport system permease protein AraQ, component of The arabinosaccharide transporter AraNPQMsmX. Transports α-1,5-arabinooligosaccharides, at least up to four L-arabinosyl units; the key transporter for α-1,5-arabinotriose and α-1,5-arabinotetraose, but not for α-1,5-arabinobiose which is transported by AraE. MsmX is also used by the MdxEFG-MsmX system (3.A.1.1.36) (Ferreira and Sá-Nogueira, 2010). Involved in the uptake of pectin oligosaccharides with either MsmX or YurJ as the ATPase from Bacillus subtilis (see 5 papers)
30% identity, 97% coverage of query (116 bits)
TC 3.A.1.1.39 / Q9WYR1 Alpha-1,4-digalacturonate porter (Nanavati et al., 2006). Regulated by pectin utilization regulon UxaR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
28% identity, 100% coverage of query (116 bits)
Ac3H11_794 ABC transporter for Glycerol, permease component 2 from Acidovorax sp. GW101-3H11
28% identity, 99% coverage of query (115 bits)
Q9X0S9 ABC-type maltose transporter (subunit 2/2) (EC 7.5.2.1) from Thermotoga maritima (see paper)
TC 3.A.1.1.22 / Q9X0S9 MalG1; aka Maltose ABC transporter, permease protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
34% identity, 75% coverage of query (115 bits)
TC 3.A.1.1.24 / Q72KX4 Sugar transport system permease protein aka TT_C0326, component of The glucose/mannose porter TTC0326-8 plus MalK1 (ABC protein, shared with 3.A.1.1.25) from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
29% identity, 96% coverage of query (114 bits)
PGA1_c13190 ABC transporter for D-Sorbitol, permease component 1 from Phaeobacter inhibens BS107
31% identity, 98% coverage of query (112 bits)
TC 3.A.1.1.26 / O06991 MalG aka yvdI, component of The maltose porter, MdxEFG and MsmX from Bacillus subtilis (see 2 papers)
27% identity, 100% coverage of query (110 bits)
SMc04257 ABC transporter for D-Cellobiose and D-Salicin, permease component 1 from Sinorhizobium meliloti 1021
29% identity, 98% coverage of query (110 bits)
TC 3.A.1.1.16 / Q8TZQ0 MalG, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus
33% identity, 78% coverage of query (110 bits)
BWI76_RS01820 maltose ABC transporter, permease component 2 (MalG) from Klebsiella michiganensis M5al
36% identity, 75% coverage of query (109 bits)
G9MB86 ABC-type glycerol 3-phosphate transporter (subunit 1/3) (EC 7.6.2.10) from Thermus thermophilus (see paper)
31% identity, 88% coverage of query (109 bits)
MalG / b4032 maltose ABC transporter membrane subunit MalG (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
MalG / P68183 maltose ABC transporter membrane subunit MalG (EC 7.5.2.1) from Escherichia coli (strain K12) (see 6 papers)
MALG_ECOLI / P68183 Maltose/maltodextrin transport system permease protein MalG from Escherichia coli (strain K12) (see 5 papers)
P68183 ABC-type maltose transporter (subunit 2/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68183 Maltose transport system permease protein MalG aka B4032, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 13 papers)
malG / RF|NP_418456 maltose transport system permease protein malG from Escherichia coli K12 (see 15 papers)
36% identity, 75% coverage of query (107 bits)
TC 3.A.1.1.38 / Q9WYQ1 Sugar ABC transporter, permease protein, component of Inositol phosphate porter (Rodionova et al. 2013). Binds inositol phosphate with low Kd and inositol with a lower affinity from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
28% identity, 91% coverage of query (105 bits)
Psest_0865 maltose ABC transporter, permease component 2 (MalG) from Pseudomonas stutzeri RCH2
34% identity, 75% coverage of query (104 bits)
TC 3.A.1.1.48 / D6ZW62 Permease of ABC transporter for sugars, component of The lacto-N-biose I (LNB; Gal β-1,3-GlcNAc)/galacto-N-biose (GNB; Gal β-1,3-GalNAc) transporter from Bifidobacterium longum subsp. longum (strain JDM301)
30% identity, 92% coverage of query (103 bits)
Ac3H11_2942 ABC transporter for D-Sorbitol, permease component 1 from Acidovorax sp. GW101-3H11
31% identity, 93% coverage of query (101 bits)
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Lawrence Berkeley National Laboratory