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Searching for up to 100 curated homologs for WP_111607229.1 NCBI__GCF_003259225.1:WP_111607229.1 (345 a.a.)

Found high-coverage hits (≥70%) to 41 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AnsA / b1767 L-asparaginase 1 (EC 3.5.1.38; EC 3.5.1.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ansA / P0A962 L-asparaginase 1 (EC 3.5.1.38) from Escherichia coli (strain K12) (see 11 papers)
ASPG1_ECOLI / P0A962 L-asparaginase 1; L-asparaginase I; L-ASNase I; L-asparagine amidohydrolase I; EC 3.5.1.1 from Escherichia coli (strain K12) (see paper)
    42% identity, 98% coverage of query (249 bits)

6nxcB / P0A962 Ecai(t162a) mutant in complex with citrate at ph 4 (see paper)
    40% identity, 98% coverage of query (234 bits)

2himA Crystal structure and allosteric regulation of the cytoplasmic escherichia coli l-asparaginase i
    40% identity, 98% coverage of query (222 bits)

CA265_RS25090 L-asparaginase (EC 3.5.1.1) from Pedobacter sp. GW460-11-11-14-LB5
    38% identity, 93% coverage of query (203 bits)

7r6bB / A0A3N4B0Q2 Crystal structure of mutant r43d/l124d/r125a/c273s of l-asparaginase i from yersinia pestis (see paper)
    38% identity, 98% coverage of query (199 bits)

4r8lA Crystal structure of the asp-bound guinea pig l-asparaginase 1 catalytic domain
    36% identity, 93% coverage of query (185 bits)

W0G253 asparaginase (EC 3.5.1.1) from Rhizomucor miehei (see paper)
    36% identity, 92% coverage of query (184 bits)

LPP60_RAT / O88202 60 kDa lysophospholipase; Lysophospholipase-transacylase; EC 3.1.1.5; EC 3.5.1.1; EC 3.1.1.47 from Rattus norvegicus (Rat) (see 3 papers)
    36% identity, 92% coverage of query (184 bits)

H0W0T5 asparaginase (EC 3.5.1.1) from Cavia porcellus (see paper)
    36% identity, 93% coverage of query (184 bits)

5dndD / H0W0T5 Crystal structure of the asn-bound guinea pig l-asparaginase 1 catalytic domain active site mutant t116a (see paper)
    36% identity, 93% coverage of query (183 bits)

PfGW456L13_740 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens GW456-L13
    38% identity, 98% coverage of query (180 bits)

A0JNU3 1-alkyl-2-acetylglycerophosphocholine esterase (subunit 3/3) (EC 3.1.1.47) from Mus musculus (see paper)
    36% identity, 92% coverage of query (179 bits)

ASPG / Q86U10 60 kDa lysophospholipase (EC 3.1.1.47; EC 3.5.1.38) from Homo sapiens (see 4 papers)
    36% identity, 99% coverage of query (177 bits)

Pf1N1B4_2023 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N1B4
    37% identity, 98% coverage of query (177 bits)

Pf6N2E2_4087 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2E2
    38% identity, 98% coverage of query (176 bits)

AO353_09960 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2E3
    36% identity, 98% coverage of query (174 bits)

AO356_11100 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2C3
    37% identity, 98% coverage of query (174 bits)

A0A1I0U0N3 asparaginase (EC 3.5.1.1) from Pseudomonas otitidis (see paper)
    35% identity, 97% coverage of query (169 bits)

ASPG_DIRIM / Q9U518 L-asparaginase; DiAsp; L-asparagine amidohydrolase; EC 3.5.1.1 from Dirofilaria immitis (Canine heartworm) (see paper)
    33% identity, 92% coverage of query (167 bits)

ASPG1_BACSU / P26900 L-asparaginase 1; L-ASNase 1; L-asparagine amidohydrolase 1; EC 3.5.1.1 from Bacillus subtilis (strain 168) (see paper)
    33% identity, 93% coverage of query (160 bits)

4q0mA / Q8TZE8 Crystal structure of pyrococcus furiosus l-asparaginase (see paper)
    30% identity, 98% coverage of query (140 bits)

ASPG_PYRFU / Q8TZE8 L-asparaginase; EC 3.5.1.1 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see 6 papers)
Q8TZE8 asparaginase (EC 3.5.1.1) from Pyrococcus furiosus (see 2 papers)
    30% identity, 98% coverage of query (140 bits)

1zq1A / Q9V0T9 Structure of gatde tRNA-dependent amidotransferase from pyrococcus abyssi (see paper)
    30% identity, 98% coverage of query (138 bits)

ASPG_THEKO / Q5JIW4 L-asparaginase; L-asparagine amidohydrolase; TkA; TkAsn; EC 3.5.1.1 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see 3 papers)
5ot0A / Q5JIW4 The thermostable l-asparaginase from thermococcus kodakarensis (see paper)
    31% identity, 98% coverage of query (136 bits)

Build an alignment

Build an alignment for WP_111607229.1 and 24 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

gatD / O26802 glutamyl-tRNA(Gln) amidotransferase subunit D (EC 6.3.5.7) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see paper)
    29% identity, 83% coverage of query (102 bits)

8h4aB / A0A6I7U6Y2 Blasnase-t13a/m57p
    25% identity, 95% coverage of query (67.0 bits)

7c8qA Blasnase-t13a with d-asn
    25% identity, 95% coverage of query (66.6 bits)

7c8xA Blasnase-t13a with l-asn
    26% identity, 95% coverage of query (63.5 bits)

7cbuA Blasnase-t13a with l-asp
    25% identity, 95% coverage of query (62.8 bits)

Q9ZLB9 asparaginase (EC 3.5.1.1) from Helicobacter pylori J99 (see paper)
    25% identity, 82% coverage of query (58.9 bits)

2wltA / Q9ZLB9 The crystal structure of helicobacter pylori l-asparaginase at 1.4 a resolution (see paper)
    25% identity, 82% coverage of query (56.6 bits)

B6ZCD8 asparaginase (EC 3.5.1.1) from Helicobacter pylori (see paper)
I0ZIE0 asparaginase (EC 3.5.1.1) from Helicobacter pylori (see paper)
    24% identity, 76% coverage of query (53.5 bits)

P38986 asparaginase (EC 3.5.1.1) from Saccharomyces cerevisiae (see paper)
    23% identity, 73% coverage of query (52.8 bits)

P38986 L-asparaginase 1; L-asparaginase I; L-asparagine amidohydrolase I; ASP I; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    23% identity, 73% coverage of query (52.8 bits)

ansB1 / Q6Q4F4 L-asparaginase subunit (EC 3.5.1.38) from Pectobacterium atrosepticum (see 10 papers)
Q6Q4F4 asparaginase (EC 3.5.1.1) from Pectobacterium atrosepticum (see paper)
    25% identity, 74% coverage of query (47.8 bits)

2gvnA / I1SBD9 L-asparaginase from erwinia carotovora in complex with aspartic acid (see paper)
    25% identity, 74% coverage of query (47.4 bits)

2hlnA L-asparaginase from erwinia carotovora in complex with glutamic acid
    24% identity, 74% coverage of query (47.4 bits)

6wyyA Crystal structure of pseudomonas 7a glutaminase-asparaginase in complex with l-glu at ph 6.5
    25% identity, 83% coverage of query (47.0 bits)

A0A2X5A091 asparaginase (EC 3.5.1.1); glutaminase (EC 3.5.1.2) from Helicobacter pylori (see paper)
    24% identity, 76% coverage of query (46.6 bits)

ASPG_DICCH / P06608 L-asparaginase; L-ASNase; L-asparagine amidohydrolase; EC 3.5.1.1 from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 3 papers)
    23% identity, 86% coverage of query (44.3 bits)

6wywA Crystal structure of pseudomonas 7a glutaminase-asparaginase in complex with l-asp at ph 4.5
    25% identity, 83% coverage of query (43.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory