Searching for up to 100 curated homologs for WP_226992378.1 NCBI__GCF_000429905.1:WP_226992378.1 (139 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

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Hits with ≥ 30% identity

HIS3_METTH / O26347 Phosphoribosyl-AMP cyclohydrolase; PRA-CH; EC 3.5.4.19 from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) (see paper)
    59% identity, 81% coverage of query (142 bits)

HSERO_RS20310 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) from Herbaspirillum seropedicae SmR1
    54% identity, 77% coverage of query (125 bits)

HisE / b2026 putative bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase (EC 3.5.4.19; EC 3.6.1.31) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
hisI / P06989 putative bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase (EC 3.5.4.19; EC 3.6.1.31) from Escherichia coli (strain K12) (see 5 papers)
    56% identity, 71% coverage of query (114 bits)

hisI / CAX46381.1 phosphoribosyl AMP-cyclohydrolase, partial from Chromohalobacter salexigens (see paper)
    45% identity, 90% coverage of query (113 bits)

6j2lA / P37793 Crystal structure of bi-functional enzyme (see paper)
    54% identity, 71% coverage of query (111 bits)

6j2lB Crystal structure of bi-functional enzyme
    51% identity, 71% coverage of query (106 bits)

HIS3_METVA / Q50837 Phosphoribosyl-AMP cyclohydrolase; PRA-CH; EC 3.5.4.19 from Methanococcus vannielii (see paper)
Q50837 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) from Methanococcus vannielii (see paper)
    47% identity, 83% coverage of query (92.4 bits)

7bgmA / A0A072U2X9 Crystal structure of mthisn2, a bifunctional enzyme from the histidine biosynthetic pathway (see paper)
    40% identity, 78% coverage of query (85.9 bits)

7bgnA Crystal structure of mthisn2-amp complex, a bifunctional enzyme from the histidine biosynthetic pathway
    40% identity, 78% coverage of query (85.9 bits)

HIS2_YEAST / P00815 Histidine biosynthesis trifunctional protein; EC 3.5.4.19; EC 3.6.1.31; EC 1.1.1.23 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    37% identity, 78% coverage of query (73.9 bits)

HIS2_SCHPO / O59667 Histidine biosynthesis bifunctional protein his7; EC 3.5.4.19; EC 3.6.1.31 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
his7 / GI|3006138 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase His7; EC 3.5.4.19; EC 3.6.1.31 from Schizosaccharomyces pombe (see 2 papers)
    39% identity, 73% coverage of query (67.4 bits)

A1BPP9 histidinol dehydrogenase (EC 1.1.1.23) from Geotrichum candidum (see paper)
    36% identity, 74% coverage of query (62.8 bits)

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