Searching for up to 100 curated homologs for YP_428190.1 NCBI__GCF_000013085.1:YP_428190.1 (328 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
6wj9B / Q4KCF6 Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-glcnac (see paper)
43% identity, 85% coverage of query (201 bits)
6wjaA Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-galnac
43% identity, 85% coverage of query (201 bits)
Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
36% identity, 91% coverage of query (167 bits)
6dntA / D3E402 Udp-n-acetylglucosamine 4-epimerase from methanobrevibacter ruminantium m1 in complex with udp-n-acetylmuramic acid (see paper)
33% identity, 88% coverage of query (167 bits)
F6DEY6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Thermus thermophilus (see paper)
39% identity, 91% coverage of query (152 bits)
2p5uA / Q5SKQ2 Crystal structure of thermus thermophilus hb8 udp-glucose 4-epimerase complex with NAD
41% identity, 83% coverage of query (149 bits)
F2NQX6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Marinithermus hydrothermalis (see paper)
37% identity, 91% coverage of query (148 bits)
3lu1A / Q7BJX9 Crystal structure analysis of wbgu: a udp-galnac 4-epimerase (see paper)
32% identity, 89% coverage of query (144 bits)
wbgU / Q7BJX9 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Plesiomonas shigelloides (see paper)
GNE_PLESH / Q7BJX9 UDP-N-acetylglucosamine 4-epimerase; UDP-GalNAc 4-epimerase; EC 5.1.3.7 from Plesiomonas shigelloides (Aeromonas shigelloides) (see 3 papers)
Q7BJX9 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Plesiomonas shigelloides (see 2 papers)
32% identity, 89% coverage of query (144 bits)
3ruhA Alternative analogs as viable substrates of udp-hexose 4-epimerases
32% identity, 89% coverage of query (144 bits)
3rufA Alternative analogs as viable substrates of udp-hexose 4-epimerases
32% identity, 89% coverage of query (144 bits)
Q8KN66 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Pseudomonas aeruginosa (see paper)
1sb8A / Q8KN66 Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-n-acetylgalactosamine (see paper)
30% identity, 94% coverage of query (142 bits)
1sb9A Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-glucose
30% identity, 94% coverage of query (142 bits)
A3MUJ4 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrobaculum calidifontis (see paper)
37% identity, 77% coverage of query (139 bits)
GALE_LACHE / Q7WTB1 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Lactobacillus helveticus (Lactobacillus suntoryeus) (see paper)
32% identity, 82% coverage of query (138 bits)
wbpP / Q9RHD6 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Pseudomonas aeruginosa (see 8 papers)
30% identity, 94% coverage of query (138 bits)
UAE / Q868I5 UDP-N-acetylglucosamine 4'-epimerase (EC 5.1.3.7) from Giardia intestinalis (see 7 papers)
30% identity, 93% coverage of query (136 bits)
tunF / E5KJ99 UDP-6-deoxy-5,6-ene-GlcNAc 4-epimerase (EC 5.1.3.7) from Streptomyces chartreusis (see paper)
35% identity, 82% coverage of query (135 bits)
6pnlA / O26475 Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
31% identity, 95% coverage of query (133 bits)
6pmhA Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
32% identity, 92% coverage of query (132 bits)
8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
33% identity, 91% coverage of query (126 bits)
O73960 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrococcus horikoshii (see paper)
32% identity, 77% coverage of query (123 bits)
UXS1 / Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
UXS1_ARATH / Q8VZC0 UDP-glucuronic acid decarboxylase 1; UDP-XYL synthase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
32% identity, 91% coverage of query (122 bits)
uxe / Q92WA3 UDP-xylose 4-epimerase subunit (EC 5.1.3.5) from Rhizobium meliloti (strain 1021) (see paper)
Q92WA3 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Sinorhizobium meliloti (see paper)
32% identity, 86% coverage of query (120 bits)
UXS1_HUMAN / Q8NBZ7 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; hUXS; hUXS1; EC 4.1.1.35 from Homo sapiens (Human) (see 3 papers)
32% identity, 78% coverage of query (119 bits)
galE / CAA89986.1 UDP-galactose 4-epimease from Corynebacterium glutamicum (see paper)
31% identity, 82% coverage of query (119 bits)
UXS1_RAT / Q5PQX0 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Rattus norvegicus (Rat) (see paper)
32% identity, 78% coverage of query (119 bits)
2b69A / Q8NBZ7 Crystal structure of human udp-glucoronic acid decarboxylase
32% identity, 78% coverage of query (119 bits)
epsS / BAC55147.1 UDP-glucose 4-epimerase EpsS from Methylobacillus sp. 12S (see paper)
31% identity, 82% coverage of query (119 bits)
UXS1_DANRE / Q6GMI9 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UXS-1; EC 4.1.1.35 from Danio rerio (Zebrafish) (Brachydanio rerio) (see 3 papers)
30% identity, 91% coverage of query (119 bits)
Build an alignment for YP_428190.1 and 30 homologs with ≥ 30% identity
Or download the sequences
6bwlA / Q3ESA4 X-ray structure of pal from bacillus thuringiensis (see paper)
29% identity, 91% coverage of query (118 bits)
uxs1 / Q92WA4 UDP-xylose synthase 1 subunit (EC 4.1.1.35) from Rhizobium meliloti (strain 1021) (see paper)
31% identity, 91% coverage of query (116 bits)
WBIB_BURTA / Q2SYH7 dTDP-L-rhamnose 4-epimerase; EC 5.1.3.25 from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CCUG 48851 / CIP 106301 / E264) (see paper)
Q2SYH7 dTDP-L-rhamnose 4-epimerase (EC 5.1.3.25) from Burkholderia thailandensis (see paper)
30% identity, 90% coverage of query (116 bits)
galE / CAB44218.1 UDP-galactose 4-epimerase from Lactococcus lactis (see paper)
28% identity, 78% coverage of query (115 bits)
desIV / Q9ZGH3 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces venezuelae (see paper)
32% identity, 91% coverage of query (115 bits)
6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
31% identity, 90% coverage of query (115 bits)
Q75PK6 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-1 / BAD12491.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
32% identity, 91% coverage of query (115 bits)
6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
31% identity, 90% coverage of query (115 bits)
6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
31% identity, 90% coverage of query (115 bits)
3aw9A / A3MUJ4 Structure of udp-galactose 4-epimerase mutant
35% identity, 77% coverage of query (114 bits)
GALE_MYCS2 / A0R5C5 UDP-glucose 4-epimerase; UDP-galactose 4-epimerase; Uridine diphosphate galactose 4-epimerase; EC 5.1.3.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
36% identity, 91% coverage of query (114 bits)
GAE4 / O22141 subunit of UDP-GlcA 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
GAE4_ARATH / O22141 UDP-glucuronate 4-epimerase 4; UDP-glucuronic acid epimerase 4; AtUGlcAE1; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O22141 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 4 papers)
30% identity, 93% coverage of query (114 bits)
1r66A / Q9ZGH3 Crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with NAD and tyd bound (see paper)
32% identity, 91% coverage of query (114 bits)
1r6dA Crystal structure of desiv double mutant (dtdp-glucose 4,6- dehydratase) from streptomyces venezuelae with NAD and dau bound
32% identity, 91% coverage of query (114 bits)
N0A9U2 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
34% identity, 90% coverage of query (113 bits)
LPSL_RHIME / O54067 Probable UDP-glucuronate 4-epimerase; UDP-glucuronic acid epimerase; EC 5.1.3.6 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
29% identity, 90% coverage of query (113 bits)
GalD / b0759 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli K-12 substr. MG1655 (see 42 papers)
galE / P09147 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli (strain K12) (see 38 papers)
GALE_ECOLI / P09147 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Escherichia coli (strain K12) (see 13 papers)
29% identity, 86% coverage of query (113 bits)
N0A0C4 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
32% identity, 92% coverage of query (113 bits)
6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
30% identity, 90% coverage of query (113 bits)
2udpA Udp-galactose 4-epimerase complexed with udp-phenol
29% identity, 86% coverage of query (113 bits)
1udcA Structure of udp-galactose-4-epimerase complexed with udp-mannose
29% identity, 86% coverage of query (113 bits)
1udaA Structure of udp-galactose-4-epimerase complexed with udp-4-deoxy-4- fluoro-alpha-d-galactose
29% identity, 86% coverage of query (113 bits)
1naiA Udp-galactose 4-epimerase from escherichia coli, oxidized
29% identity, 86% coverage of query (113 bits)
1lrjA Crystal structure of e. Coli udp-galactose 4-epimerase complexed with udp-n-acetylglucosamine
29% identity, 86% coverage of query (113 bits)
gla / P96481 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Streptococcus pneumoniae (see 2 papers)
28% identity, 91% coverage of query (112 bits)
galE / P21977 UDP-glucose-4-epimerase (EC 5.1.3.2) from Streptococcus thermophilus (see paper)
GALE_STRTR / P21977 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Streptococcus thermophilus (see paper)
P21977 UDP-glucose 4-epimerase (EC 5.1.3.2) from Streptococcus thermophilus (see paper)
29% identity, 81% coverage of query (112 bits)
1kvrA Udp-galactose 4-epimerase complexed with udp-phenol
29% identity, 86% coverage of query (112 bits)
7ysmA Crystal structure of udp-glucose 4-epimerase (rv3634c) co-crystallized with udp-n-acetylglucosamine from mycobacterium tuberculosis
35% identity, 91% coverage of query (112 bits)
5u4qA 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
30% identity, 90% coverage of query (111 bits)
7ystA / P9WN67 Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chain b from mycobacterium tuberculosis
35% identity, 91% coverage of query (111 bits)
galE1 / P9WN67 UDP-galactose/glucose 4-epimerase subunit (EC 5.1.3.7; EC 5.1.3.2) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WN67 UDP-glucose 4-epimerase (EC 5.1.3.2) from Mycobacterium tuberculosis (see paper)
35% identity, 91% coverage of query (111 bits)
7ys9A Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chaina from mycobacterium tuberculosis
35% identity, 91% coverage of query (111 bits)
6kvcA Moee5 in complex with udp-glucose and NAD
36% identity, 90% coverage of query (111 bits)
1a9yA / P09147 Udp-galactose 4-epimerase mutant s124a/y149f complexed with udp- glucose (see paper)
28% identity, 86% coverage of query (110 bits)
Q8W3J1 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-4 / BAB84333.2 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
33% identity, 89% coverage of query (110 bits)
GAE3_ARATH / O81312 UDP-glucuronate 4-epimerase 3; UDP-glucuronic acid epimerase 3; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
O81312 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
31% identity, 91% coverage of query (110 bits)
2c20A / A0A6L8PTV5 Crystal structure of udp-glucose 4-epimerase
28% identity, 81% coverage of query (110 bits)
N0A422 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
32% identity, 90% coverage of query (110 bits)
Q75PK7 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-2 / BAD12490.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
32% identity, 91% coverage of query (110 bits)
6kv9A / A0A003 Moee5 in complex with udp-glucuronic acid and NAD (see paper)
36% identity, 90% coverage of query (108 bits)
3vpsA / E5KJ94 Structure of a novel NAD dependent-ndp-hexosamine 5,6-dehydratase, tuna, involved in tunicamycin biosynthesis
35% identity, 82% coverage of query (107 bits)
2q1sA / O87989 Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with nadh (see paper)
29% identity, 91% coverage of query (105 bits)
2q1tA Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with NAD+ and udp
29% identity, 91% coverage of query (103 bits)
4twrA / Q2YKG6 Structure of udp-glucose 4-epimerase from brucella abortus
31% identity, 82% coverage of query (102 bits)
2pzjA Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with NAD+
30% identity, 84% coverage of query (102 bits)
GALE / Q14376 UDP-galactose 4-epimerase (EC 5.1.3.2; EC 5.1.3.7) from Homo sapiens (see 6 papers)
GALE_HUMAN / Q14376 UDP-glucose 4-epimerase; Galactowaldenase; UDP-N-acetylgalactosamine 4-epimerase; UDP-GalNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2; EC 5.1.3.7 from Homo sapiens (Human) (see 12 papers)
Q14376 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Homo sapiens (see 4 papers)
27% identity, 84% coverage of query (101 bits)
1ek6A Structure of human udp-galactose 4-epimerase complexed with nadh and udp-glucose
27% identity, 84% coverage of query (101 bits)
8wovB / Q9T0A7 Crystal structure of arabidopsis thaliana udp-glucose 4-epimerase 2 (atuge2) complexed with udp, g233a mutant (see paper)
30% identity, 88% coverage of query (100 bits)
4lk3C Crystal structure of human udp-xylose synthase r236a substitution
30% identity, 91% coverage of query (100 bits)
1hzjA Human udp-galactose 4-epimerase: accommodation of udp-n- acetylglucosamine within the active site
27% identity, 84% coverage of query (100 bits)
4lk3B / Q8NBZ7 Crystal structure of human udp-xylose synthase r236a substitution (see paper)
31% identity, 91% coverage of query (100 bits)
1i3lA Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase
27% identity, 84% coverage of query (99.4 bits)
1i3kA / Q14376 Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase (see paper)
27% identity, 84% coverage of query (99.4 bits)
7k3pA / Q0P9C3 The structure of the udp-glc/glcnac 4-epimerase from the human pathogen campylobacter jejuni
28% identity, 82% coverage of query (98.6 bits)
4lisA / C8VAU8 Crystal structure of udp-galactose-4-epimerase from aspergillus nidulans (see paper)
29% identity, 82% coverage of query (97.4 bits)
4lisB Crystal structure of udp-galactose-4-epimerase from aspergillus nidulans
29% identity, 82% coverage of query (97.4 bits)
2c59A / Q93VR3 Gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha- d-mannose and gdp-beta-l-galactose bound in the active site. (see paper)
26% identity, 83% coverage of query (97.4 bits)
MUR4 / Q9SA77 UDP-D-xylose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see 3 papers)
ARAE1_ARATH / Q9SA77 UDP-arabinose 4-epimerase 1; UDP-D-xylose 4-epimerase 1; EC 5.1.3.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9SA77 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see paper)
28% identity, 83% coverage of query (97.1 bits)
GME / Q93VR3 GDP-D-mannose-3,5-epimerase (EC 5.1.3.18) from Arabidopsis thaliana (see paper)
GME_ARATH / Q93VR3 GDP-mannose 3,5-epimerase; GDP-Man 3,5-epimerase; EC 5.1.3.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
26% identity, 83% coverage of query (97.1 bits)
8sk0B / A0A1C5ADV9 Crystal structure of evds6 decarboxylase in ligand bound state (see paper)
29% identity, 91% coverage of query (96.3 bits)
8sk0A Crystal structure of evds6 decarboxylase in ligand bound state
29% identity, 91% coverage of query (96.3 bits)
2c54A Gdp-mannose-3', 5' -epimerase (arabidopsis thaliana),k178r, with gdp- beta-l-gulose and gdp-4-keto-beta-l-gulose bound in active site.
25% identity, 83% coverage of query (96.3 bits)
7xpqA Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glcnac
30% identity, 84% coverage of query (95.9 bits)
7xpoA / C0HI30 Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glc (see paper)
30% identity, 84% coverage of query (95.9 bits)
5u4qB 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
31% identity, 78% coverage of query (95.1 bits)
3enkA / Q3JPI3 1.9a crystal structure of udp-glucose 4-epimerase from burkholderia pseudomallei
29% identity, 84% coverage of query (93.6 bits)
2cnbA Trypanosoma brucei udp-galactose-4-epimerase in ternary complex with NAD and the substrate analogue udp-4-deoxy-4-fluoro-alpha-d-galactose
28% identity, 82% coverage of query (93.2 bits)
1gy8C / Q8T8E9 Trypanosoma brucei udp-galactose 4' epimerase (see paper)
27% identity, 82% coverage of query (91.7 bits)
RHM2 / Q9LPG6 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM2 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM2_ARATH / Q9LPG6 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2; NDP-rhamnose synthase; Protein MUCILAGE-MODIFIED 4; Protein RHAMNOSE BIOSYNTHESIS 2; Rhamnose biosynthetic enzyme 2; AtRHM2; UDP-L-rhamnose synthase MUM4; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
28% identity, 80% coverage of query (89.0 bits)
1z45A / P04397 Crystal structure of the gal10 fusion protein galactose mutarotase/udp-galactose 4-epimerase from saccharomyces cerevisiae complexed with NAD, udp-glucose, and galactose (see paper)
28% identity, 79% coverage of query (89.0 bits)
Or start over
Lawrence Berkeley National Laboratory