Searching for up to 100 curated homologs for mRNA_6818 (72 a.a.)
Found high-coverage hits (≥70%) to 84 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q8BVQ9 proteasome ATPase (EC 5.6.1.5) from Mus musculus (see paper)
77% identity, 99% coverage of query (117 bits)
PRS7_HUMAN / P35998 26S proteasome regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; Proteasome 26S subunit ATPase 2 from Homo sapiens (Human) (see 11 papers)
77% identity, 99% coverage of query (116 bits)
PRS7_MOUSE / P46471 26S proteasome regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; Proteasome 26S subunit ATPase 2 from Mus musculus (Mouse) (see 2 papers)
77% identity, 99% coverage of query (116 bits)
8uscA / P35998 8uscA
77% identity, 99% coverage of query (116 bits)
5vfpA 26S proteasome regulatory subunit 6A
77% identity, 99% coverage of query (116 bits)
5gjqH Structure of the human 26s proteasome bound to usp14-ubal
77% identity, 99% coverage of query (116 bits)
9e8iA 26S proteasome regulatory subunit 7
77% identity, 99% coverage of query (116 bits)
PRS7_YEAST / P33299 26S proteasome regulatory subunit 7 homolog; Protein CIM5; Tat-binding homolog 3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
P33299 proteasome ATPase (EC 5.6.1.5) from Saccharomyces cerevisiae (see 2 papers)
77% identity, 99% coverage of query (115 bits)
6fvtH / P33299 6fvtH (see paper)
76% identity, 100% coverage of query (115 bits)
7qo4H / P33299 26s proteasome wt-ubp6-ubvs complex in the si state (atpases, rpn1, ubp6, and ubvs)
76% identity, 100% coverage of query (115 bits)
6fvuH 26S proteasome regulatory subunit 7 homolog
76% identity, 100% coverage of query (115 bits)
O42931 26S proteasome regulatory subunit 7 homolog from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
73% identity, 97% coverage of query (115 bits)
PRS7A_ARATH / Q9SSB5 26S proteasome regulatory subunit 7 homolog A; 26S proteasome AAA-ATPase subunit RPT1a; 26S proteasome subunit 7 homolog A; Regulatory particle triple-A ATPase subunit 1a from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
72% identity, 99% coverage of query (108 bits)
8amzH / Q41365 Spinach 19s proteasome
72% identity, 99% coverage of query (108 bits)
5mpbH proteasome in presence of AMP-PNP (s3)
79% identity, 86% coverage of query (104 bits)
6ef0H Yeast 26s proteasome bound to ubiquitinated substrate (1d Motor state)
79% identity, 86% coverage of query (103 bits)
PRS7B_ARATH / Q9SSB4 26S proteasome regulatory subunit 7 homolog B; 26S proteasome AAA-ATPase subunit RPT1b; 26S proteasome subunit 7 homolog B; Regulatory particle triple-A ATPase subunit 1b from Arabidopsis thaliana (Mouse-ear cress) (see paper)
66% identity, 99% coverage of query (101 bits)
PRS4_ENCCU / Q8SRH0 26S proteasome regulatory subunit 4 homolog from Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) (see paper)
42% identity, 96% coverage of query (63.2 bits)
5m32h / P62195 Human 26s proteasome in complex with oprozomib (see paper)
49% identity, 79% coverage of query (59.3 bits)
PRS8_HUMAN / P62195 26S proteasome regulatory subunit 8; 26S proteasome AAA-ATPase subunit RPT6; Proteasome 26S subunit ATPase 5; Proteasome subunit p45; Thyroid hormone receptor-interacting protein 1; TRIP1; p45/SUG from Homo sapiens (Human) (see 9 papers)
PRS8_MOUSE / P62196 26S proteasome regulatory subunit 8; 26S proteasome AAA-ATPase subunit RPT6; Proteasome 26S subunit ATPase 5; Proteasome subunit p45; p45/SUG; mSUG1 from Mus musculus (Mouse) (see 2 papers)
PRS8_RAT / P62198 26S proteasome regulatory subunit 8; 26S proteasome AAA-ATPase subunit RPT6; Proteasome 26S subunit ATPase 5; Proteasome subunit p45; Thyroid hormone receptor-interacting protein 1; TRIP1; p45/SUG from Rattus norvegicus (Rat) (see paper)
P62196 proteasome ATPase (EC 5.6.1.5) from Mus musculus (see paper)
49% identity, 79% coverage of query (59.3 bits)
6msgC / P62195 6msgC (see paper)
49% identity, 79% coverage of query (58.9 bits)
PRS8_DROME / O18413 26S proteasome regulatory subunit 8 from Drosophila melanogaster (Fruit fly) (see 2 papers)
O18413 proteasome endopeptidase complex (EC 3.4.25.1) from Drosophila melanogaster (see paper)
49% identity, 79% coverage of query (58.9 bits)
9e8jC Nub1/fat10-processing human 26s proteasome bound to txnl1 with rpt1 at top of spiral staircase
49% identity, 79% coverage of query (58.9 bits)
5gjqJ Structure of the human 26s proteasome bound to usp14-ubal
49% identity, 79% coverage of query (58.9 bits)
5vfqC 26S proteasome regulatory subunit 8
49% identity, 79% coverage of query (58.9 bits)
PRS8_CAEEL / Q9XTT9 26S proteasome regulatory subunit 8; 26S proteasome AAA-ATPase subunit rpt-6; Proteasome regulatory particle ATPase-like protein 6 from Caenorhabditis elegans (see paper)
51% identity, 79% coverage of query (57.4 bits)
5eqtA / O57940 Crystal structure of the atpase domain of pan from pyrococcus horikoshii
49% identity, 71% coverage of query (56.6 bits)
let1 / AAA61615.1 Let1 from Schizosaccharomyces pombe (see paper)
49% identity, 82% coverage of query (56.6 bits)
O28303 proteasome ATPase (EC 5.6.1.5) from Archaeoglobus fulgidus (see 2 papers)
42% identity, 79% coverage of query (56.2 bits)
6he8I / O28303 Pan-proteasome in state 1 (see paper)
42% identity, 79% coverage of query (56.2 bits)
6he4L Aaa-atpase ring of pan-proteasomes
42% identity, 79% coverage of query (56.2 bits)
6heaJ Pan-proteasome in state 3
42% identity, 79% coverage of query (56.2 bits)
PRS8B_ARATH / Q94BQ2 26S proteasome regulatory subunit 8 homolog B; 26S proteasome AAA-ATPase subunit RPT6b; 26S proteasome subunit 8 homolog B; Regulatory particle triple-A ATPase subunit 6b from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
49% identity, 79% coverage of query (55.1 bits)
PRS8A_ARATH / Q9C5U3 26S proteasome regulatory subunit 8 homolog A; 26S proteasome AAA-ATPase subunit RPT6a; 26S proteasome subunit 8 homolog A; Regulatory particle triple-A ATPase subunit 6a from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
49% identity, 79% coverage of query (55.1 bits)
PS10A_ARATH / Q9SEI3 26S proteasome regulatory subunit 10B homolog A; 26S proteasome AAA-ATPase subunit RPT4a; 26S proteasome subunit 10B homolog A; Regulatory particle triple-A ATPase subunit 4a from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
44% identity, 86% coverage of query (54.7 bits)
PAN1_HALVD / D4GUJ7 Proteasome-activating nucleotidase 1; PAN 1; Proteasomal ATPase 1; Proteasome regulatory ATPase 1; Proteasome regulatory particle 1 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 4 papers)
D4GUJ7 proteasome ATPase (EC 5.6.1.5) from Haloferax volcanii (see 2 papers)
45% identity, 76% coverage of query (54.7 bits)
PS10B_ARATH / Q9MAK9 26S proteasome regulatory subunit S10B homolog B; 26S proteasome AAA-ATPase subunit RPT4b; 26S proteasome subunit S10B homolog B; Regulatory particle triple-A ATPase subunit 4b from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
41% identity, 94% coverage of query (54.3 bits)
Q9U7A2 proteasome endopeptidase complex (EC 3.4.25.1) from Drosophila melanogaster (see paper)
47% identity, 76% coverage of query (53.9 bits)
PRS8_ENCCU / Q8SQK0 26S proteasome regulatory subunit 8 homolog from Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) (see paper)
41% identity, 89% coverage of query (52.8 bits)
9e8lE Nub1/fat10-processing human 26s proteasome bound to txnl1 with rpt4 at top of spiral staircase
48% identity, 72% coverage of query (52.0 bits)
3h4mA / Q58576 Aaa atpase domain of the proteasome- activating nucleotidase (see paper)
43% identity, 78% coverage of query (51.6 bits)
PRS10_HUMAN / P62333 26S proteasome regulatory subunit 10B; 26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42 from Homo sapiens (Human) (see 4 papers)
PRS10_MOUSE / P62334 26S proteasome regulatory subunit 10B; 26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42 from Mus musculus (Mouse) (see paper)
P62334 proteasome ATPase (EC 5.6.1.5) from Mus musculus (see paper)
5l4gL / P62333 human 26S proteasome at 3.9 A (see paper)
48% identity, 72% coverage of query (51.6 bits)
PAN_METJA / Q58576 Proteasome-activating nucleotidase; PAN; Proteasomal ATPase; Proteasome regulatory ATPase; Proteasome regulatory particle from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 7 papers)
Q58576 proteasome ATPase (EC 5.6.1.5) from Methanocaldococcus jannaschii (see paper)
43% identity, 78% coverage of query (51.6 bits)
5vfpE 26S proteasome regulatory subunit 6A
48% identity, 72% coverage of query (51.6 bits)
5gjqL Structure of the human 26s proteasome bound to usp14-ubal
48% identity, 72% coverage of query (51.6 bits)
6mseE 26S proteasome regulatory subunit 6A
48% identity, 72% coverage of query (51.6 bits)
5mpbJ proteasome in presence of AMP-PNP (s3)
41% identity, 85% coverage of query (50.1 bits)
PRS8_YEAST / Q01939 26S proteasome regulatory subunit 8 homolog; Protein CIM3; Protein SUG1; Tat-binding protein TBY1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
Q01939 proteasome ATPase (EC 5.6.1.5) from Saccharomyces cerevisiae (see 2 papers)
6fvtJ / Q01939 6fvtJ (see paper)
41% identity, 85% coverage of query (49.7 bits)
5mpcJ proteasome in presence of BeFx (s4)
41% identity, 85% coverage of query (49.7 bits)
PRS6A_ENCCU / Q8SR13 26S proteasome regulatory subunit 6A from Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) (see paper)
36% identity, 78% coverage of query (48.5 bits)
PRS4_HUMAN / P62191 26S proteasome regulatory subunit 4; P26s4; 26S proteasome AAA-ATPase subunit RPT2; Proteasome 26S subunit ATPase 1 from Homo sapiens (Human) (see 7 papers)
PRS4_MOUSE / P62192 26S proteasome regulatory subunit 4; P26s4; 26S proteasome AAA-ATPase subunit RPT2; Proteasome 26S subunit ATPase 1 from Mus musculus (Mouse) (see 5 papers)
P62192 proteasome ATPase (EC 5.6.1.5) from Mus musculus (see paper)
31% identity, 94% coverage of query (46.6 bits)
PRS6A_CAEEL / O76371 26S protease regulatory subunit 6A; Proteasome regulatory particle ATPase-like protein 5 from Caenorhabditis elegans (see paper)
35% identity, 96% coverage of query (46.6 bits)
6msjB / P62191 6msjB (see paper)
31% identity, 94% coverage of query (46.6 bits)
9e8gB 26S proteasome regulatory subunit 4
31% identity, 94% coverage of query (46.6 bits)
6mseB 26S proteasome regulatory subunit 6A
31% identity, 94% coverage of query (46.6 bits)
Q9V3V6 proteasome endopeptidase complex (EC 3.4.25.1) from Drosophila melanogaster (see paper)
33% identity, 96% coverage of query (46.2 bits)
5vfpB 26S proteasome regulatory subunit 6A
31% identity, 94% coverage of query (46.2 bits)
Build an alignment for mRNA_6818 and 57 homologs with ≥ 30% identity
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YHS4 / AAA97498.1 ATPase from Saccharomyces cerevisiae (see paper)
29% identity, 94% coverage of query (45.8 bits)
P40327 proteasome ATPase (EC 5.6.1.5) from Saccharomyces cerevisiae (see paper)
29% identity, 94% coverage of query (45.8 bits)
P40327 26S proteasome regulatory subunit 4 homolog; Tat-binding homolog 5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
29% identity, 94% coverage of query (45.8 bits)
6fvtI / P40327 6fvtI (see paper)
29% identity, 94% coverage of query (45.4 bits)
5mpbI proteasome in presence of AMP-PNP (s3)
29% identity, 94% coverage of query (45.4 bits)
6ef0I Yeast 26s proteasome bound to ubiquitinated substrate (1d Motor state)
29% identity, 94% coverage of query (44.7 bits)
FTSH1_ARATH / Q39102 ATP-dependent zinc metalloprotease FTSH 1, chloroplastic; AtFTSH1; EC 3.4.24.- from Arabidopsis thaliana (Mouse-ear cress) (see 10 papers)
33% identity, 83% coverage of query (43.1 bits)
PS6AA_ARATH / Q9SEI2 26S proteasome regulatory subunit 6A homolog A; 26S proteasome AAA-ATPase subunit RPT5a; Proteasome 26S subunit 6A homolog A; Regulatory particle triple-A ATPase subunit 5a; Tat-binding protein 1 homolog A; TBP-1 homolog A from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
33% identity, 96% coverage of query (43.1 bits)
5gjqI Structure of the human 26s proteasome bound to usp14-ubal
32% identity, 78% coverage of query (42.4 bits)
6mseD 26S proteasome regulatory subunit 6A
40% identity, 72% coverage of query (42.4 bits)
5vfpD 26S proteasome regulatory subunit 6A
40% identity, 72% coverage of query (42.4 bits)
5gjqK Structure of the human 26s proteasome bound to usp14-ubal
40% identity, 72% coverage of query (42.4 bits)
5l4gK / P43686 human 26S proteasome at 3.9 A (see paper)
40% identity, 72% coverage of query (42.0 bits)
P54775 26S proteasome regulatory subunit 6B; 26S proteasome AAA-ATPase subunit RPT3; CIP21; MB67-interacting protein; MIP224; Proteasome 26S subunit ATPase 4; Tat-binding protein 7; TBP-7 from Mus musculus (Mouse)
40% identity, 72% coverage of query (42.0 bits)
PRS6B_HUMAN / P43686 26S proteasome regulatory subunit 6B; 26S proteasome AAA-ATPase subunit RPT3; MB67-interacting protein; MIP224; Proteasome 26S subunit ATPase 4; Tat-binding protein 7; TBP-7 from Homo sapiens (Human) (see 9 papers)
40% identity, 72% coverage of query (42.0 bits)
7qo4M 26s proteasome wt-ubp6-ubvs complex in the si state (atpases, rpn1, ubp6, and ubvs)
32% identity, 96% coverage of query (41.6 bits)
6fvtM / P33297 6fvtM (see paper)
32% identity, 96% coverage of query (41.6 bits)
PRS6A_YEAST / P33297 26S proteasome regulatory subunit 6A; Tat-binding protein homolog 1; TBP-1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P33297 proteasome ATPase (EC 5.6.1.5) from Saccharomyces cerevisiae (see paper)
32% identity, 96% coverage of query (41.2 bits)
5mpbM proteasome in presence of AMP-PNP (s3)
32% identity, 96% coverage of query (41.2 bits)
5mp9M / P33297 26s proteasome in presence of atp (s1) (see paper)
32% identity, 96% coverage of query (41.2 bits)
FTSH_THEMA / Q9WZ49 ATP-dependent zinc metalloprotease FtsH; EC 3.4.24.- from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
35% identity, 71% coverage of query (40.8 bits)
2ceaC Cell division protein ftsh
35% identity, 71% coverage of query (40.8 bits)
2ce7C Edta treated
35% identity, 71% coverage of query (40.8 bits)
3kdsE / Q9WZ49 Apo-ftsh crystal structure (see paper)
35% identity, 71% coverage of query (40.4 bits)
2ce7D / Q9WZ49 Edta treated (see paper)
35% identity, 71% coverage of query (40.4 bits)
8vw9A / Q9WZ49 Cryoem structure of a ftsh helical assembly in the presence of atp (see paper)
35% identity, 71% coverage of query (40.4 bits)
8vwaA Cryoem structure of a ftsh helical assembly in the presence of atp
35% identity, 71% coverage of query (40.4 bits)
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Lawrence Berkeley National Laboratory