Changes to amino acid biosynthesis since the original 2019 publication: arg: Better describe the lysW-based pathway and argX. ile: Improved definition of cimA. lys: Improved the lysW-based pathway to include genes from Thermococcus kodakarensis. met: Added the core methionine synthase mesB, the mesD-mesX system, and renamed metE' to mesA. phe: Improved definition of prephenate dehydratase. pro: Added synthesis via ornithine gamma-aminotransferase (EC 2.6.1.13), and allow more options for ornithine biosynthesis (such as the lysW pathway). tyr: Improved definition of prephenate dehydrogenase.