# Candidate

orgId: NCBI__GCA_002763895.1
pathwayId: chorismate
stepId: aroL
locusId: PIO47289.1
sysName: CMR00_11215
desc: DNA polymerase III subunit gamma/tau
curatedIds: curated2:Q9X5D1
otherIds:
CharProtDB::CH_002351,CharProtDB::CH_024906,SwissProt::P06710,ecocyc::EG10245-MONOMER,metacyc::EG10245-MONOMER,metacyc::MONOMER0-2383


orgId: NCBI__GCA_002763895.1
pathwayId: his
stepId: hisA
locusId: PIO47249.1
sysName: CMR00_11460
desc: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
curatedIds: reanno::HerbieS:HSERO_RS20320
hmmId: TIGR00007
hmmDesc:
hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (EC 5.3.1.16)


orgId: NCBI__GCA_002763895.1
pathwayId: met
stepId: metH
locusId: PIO49247.1
sysName: CMR00_00810
desc: methionine synthase
hmmId: TIGR02082
hmmDesc: metH: methionine synthase (EC 2.1.1.13)
curatedIds:
CharProtDB::CH_090726,SwissProt::P13009,ecocyc::HOMOCYSMETB12-MONOMER,metacyc::HOMOCYSMETB12-MONOMER


orgId: NCBI__GCA_002763895.1
pathwayId: phe
stepId: PPYAT
locusId: PIO47097.1
sysName: CMR00_12185
desc: branched chain amino acid aminotransferase
curatedIds:
CharProtDB::CH_024500,ecocyc::BRANCHED-CHAINAMINOTRANSFER-MONOMER,metacyc::BRANCHED-CHAINAMINOTRANSFER-MONOMER


orgId: NCBI__GCA_002763895.1
pathwayId: thr
stepId: thrC
locusId: PIO47549.1
sysName: CMR00_09615
desc: threonine synthase
hmmId: TIGR00260
hmmDesc: thrC: threonine synthase (EC 4.2.3.1)
otherIds: SwissProt::Q80W22
curatedIds:
BRENDA::P00934,CharProtDB::CH_002114,SwissProt::P00934,ecocyc::THRESYN-MONOMER,metacyc::THRESYN-MONOMER


# RequirementNotMet

orgId: NCBI__GCA_002763895.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


