# Candidate

orgId: NCBI__GCA_013824085.1
pathwayId: arg
stepId: argD'B
locusId: MBA4310411.1
sysName: C0425_08755
desc: aspartate aminotransferase family protein
otherIds: BRENDA::D1C218
curatedIds:
CharProtDB::CH_002469,SwissProt::P77581,ecocyc::SUCCORNTRANSAM-MONOMER,metacyc::SUCCORNTRANSAM-MONOMER


orgId: NCBI__GCA_013824085.1
pathwayId: cys
stepId: serA
locusId: MBA4310089.1
sysName: C0425_07095
desc: phosphoglycerate dehydrogenase
curatedIds:
BRENDA::C3SVM7,BRENDA::P0A9T0,CharProtDB::CH_088336,SwissProt::P0A9T0,ecocyc::PGLYCDEHYDROG-MONOMER,metacyc::PGLYCDEHYDROG-MONOMER


orgId: NCBI__GCA_013824085.1
pathwayId: met
stepId: metH
locusId: MBA4309288.1
sysName: C0425_03005
desc: methionine synthase
hmmId: TIGR02082
hmmDesc: metH: methionine synthase (EC 2.1.1.13)
curatedIds:
CharProtDB::CH_090726,SwissProt::P13009,ecocyc::HOMOCYSMETB12-MONOMER,metacyc::HOMOCYSMETB12-MONOMER


# RequirementNotMet

orgId: NCBI__GCA_013824085.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


