# Candidate

orgId: NCBI__GCA_019694695.1
pathwayId: his
stepId: hisA
locusId: MBX7044339.1
sysName: K1X86_00765
desc: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
curatedIds: curated2:A4SG77
hmmId: TIGR00007
hmmDesc:
hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (EC 5.3.1.16)


orgId: NCBI__GCA_019694695.1
pathwayId: lys
stepId: dapH
locusId: MBX7046439.1
sysName: K1X86_11455
desc: acyltransferase
curatedIds: curated2:A8F8L8
otherIds:
BRENDA::P07464,SwissProt::P07464,ecocyc::GALACTOACETYLTRAN-MONOMER,metacyc::GALACTOACETYLTRAN-MONOMER


# RequirementNotMet

orgId: NCBI__GCA_019694695.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


