# Candidate

orgId: NCBI__GCA_020635205.1
pathwayId: cys
stepId: serA
locusId: MCB9215343.1
sysName: H6616_05625
desc: 4-phosphoerythronate dehydrogenase
curatedIds: uniprot:Q6LWW6
otherIds:
BRENDA::P05459,SwissProt::P05459,ecocyc::ERYTHRON4PDEHYDROG-MONOMER,metacyc::ERYTHRON4PDEHYDROG-MONOMER


# RequirementNotMet

orgId: NCBI__GCA_020635205.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


