# Candidate

orgId: NCBI__GCA_022763185.1
pathwayId: met
stepId: split_metH_1
locusId: MCI5072794.1
sysName: MRY82_07645
desc: methionine synthase
curatedIds: reanno::Phaeo:GFF1319
otherIds:
CharProtDB::CH_090726,SwissProt::P13009,ecocyc::HOMOCYSMETB12-MONOMER,metacyc::HOMOCYSMETB12-MONOMER


# RequirementNotMet

orgId: NCBI__GCA_022763185.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


