# Candidate

orgId: NCBI__GCA_030747075.1
pathwayId: ile
stepId: prpE
locusId: MDP6802815.1
sysName: QF819_06535
desc: long-chain fatty acid--CoA ligase
curatedIds: SwissProt::M4IQQ5,metacyc::MONOMER-20125
otherIds:
CharProtDB::CH_000804,SwissProt::P69451,TCDB::P69451,ecocyc::ACYLCOASYN-MONOMER,metacyc::ACYLCOASYN-MONOMER


# RequirementNotMet

orgId: NCBI__GCA_030747075.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


