# Candidate

orgId: NCBI__GCF_000008485.1
pathwayId: chorismate
stepId: tpiA
locusId: WP_010948480.1
sysName: LPG_RS14085
desc: triose-phosphate isomerase
hmmId: TIGR00419
hmmDesc: tpiA: triose-phosphate isomerase (EC 5.3.1.1)
curatedIds:
BRENDA::P0A858,CharProtDB::CH_024675,SwissProt::B1XB85,SwissProt::P0A858,ecocyc::TPI-MONOMER,metacyc::TPI-MONOMER


orgId: NCBI__GCF_000008485.1
pathwayId: his
stepId: hisA
locusId: WP_010946928.1
sysName: LPG_RS05955
desc: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
curatedIds: curated2:Q5X5X3
hmmId: TIGR00007
hmmDesc:
hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (EC 5.3.1.16)


orgId: NCBI__GCF_000008485.1
pathwayId: his
stepId: hisH
locusId: WP_010946929.1
sysName: LPG_RS05960
desc: imidazole glycerol phosphate synthase subunit HisH
hmmId: TIGR01855
hmmDesc: hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (EC 2.4.2.-)
curatedIds:
CharProtDB::CH_024511,SwissProt::P60595,ecocyc::GLUTAMIDOTRANS-MONOMER,metacyc::GLUTAMIDOTRANS-MONOMER


orgId: NCBI__GCF_000008485.1
pathwayId: ile
stepId: ilvD
locusId: WP_010946167.1
sysName: LPG_RS02095
desc: phosphogluconate dehydratase
curatedIds: curated2:B7JJG8
otherIds:
CharProtDB::CH_024239,SwissProt::P0ADF6,ecocyc::PGLUCONDEHYDRAT-MONOMER,metacyc::PGLUCONDEHYDRAT-MONOMER


orgId: NCBI__GCF_000008485.1
pathwayId: ile
stepId: prpE
locusId: WP_010947283.1
sysName: LPG_RS07780
desc: AMP-binding protein
curatedIds: SwissProt::M4IQQ5,metacyc::MONOMER-20125
otherIds:
CharProtDB::CH_000804,SwissProt::P69451,TCDB::P69451,ecocyc::ACYLCOASYN-MONOMER,metacyc::ACYLCOASYN-MONOMER


orgId: NCBI__GCF_000008485.1
pathwayId: trp
stepId: trpE
locusId: WP_010947286.1
sysName: LPG_RS07795
desc: aminodeoxychorismate synthase component I
curatedIds: curated2:P14953
otherIds:
CharProtDB::CH_002963,SwissProt::P05041,ecocyc::PABASYN-COMPI-MONOMER,metacyc::PABASYN-COMPI-MONOMER


# RequirementNotMet

orgId: NCBI__GCF_000008485.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


