# Candidate

orgId: NCBI__GCF_004571175.1
pathwayId: chorismate
stepId: tpiA
locusId: WP_058501265.1
sysName: E4T55_RS05820
desc: triose-phosphate isomerase
hmmId: TIGR00419
hmmDesc: tpiA: triose-phosphate isomerase (EC 5.3.1.1)
curatedIds:
BRENDA::P0A858,CharProtDB::CH_024675,SwissProt::B1XB85,SwissProt::P0A858,ecocyc::TPI-MONOMER,metacyc::TPI-MONOMER


orgId: NCBI__GCF_004571175.1
pathwayId: gly
stepId: glyA
locusId: WP_058500900.1
sysName: E4T55_RS03995
desc: serine hydroxymethyltransferase
curatedIds:
BRENDA::P0A825,CharProtDB::CH_024268,SwissProt::P0A825,ecocyc::GLYOHMETRANS-MONOMER,metacyc::GLYOHMETRANS-MONOMER


orgId: NCBI__GCF_004571175.1
pathwayId: his
stepId: hisA
locusId: WP_058501124.1
sysName: E4T55_RS04295
desc: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
curatedIds: ecocyc::PRIBFAICARPISOM-MONOMER,metacyc::PRIBFAICARPISOM-MONOMER
hmmId: TIGR00007
hmmDesc:
hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (EC 5.3.1.16)


orgId: NCBI__GCF_004571175.1
pathwayId: his
stepId: hisH
locusId: WP_058501123.1
sysName: E4T55_RS04300
desc: imidazole glycerol phosphate synthase subunit HisH
hmmId: TIGR01855
hmmDesc: hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (EC 2.4.2.-)
curatedIds:
CharProtDB::CH_024511,SwissProt::P60595,ecocyc::GLUTAMIDOTRANS-MONOMER,metacyc::GLUTAMIDOTRANS-MONOMER


orgId: NCBI__GCF_004571175.1
pathwayId: ile
stepId: ilvD
locusId: WP_058501485.1
sysName: E4T55_RS01140
desc: phosphogluconate dehydratase
curatedIds: curated2:A8AB39
otherIds:
CharProtDB::CH_024239,SwissProt::P0ADF6,ecocyc::PGLUCONDEHYDRAT-MONOMER,metacyc::PGLUCONDEHYDRAT-MONOMER


orgId: NCBI__GCF_004571175.1
pathwayId: phe
stepId: PPYAT
locusId: WP_058502445.1
sysName: E4T55_RS11595
desc: branched-chain amino acid transaminase
curatedIds:
CharProtDB::CH_024500,ecocyc::BRANCHED-CHAINAMINOTRANSFER-MONOMER,metacyc::BRANCHED-CHAINAMINOTRANSFER-MONOMER


orgId: NCBI__GCF_004571175.1
pathwayId: trp
stepId: trpE
locusId: WP_058502709.1
sysName: E4T55_RS14665
desc: aminodeoxychorismate synthase component I
curatedIds: curated2:Q02001
otherIds:
CharProtDB::CH_002963,SwissProt::P05041,ecocyc::PABASYN-COMPI-MONOMER,metacyc::PABASYN-COMPI-MONOMER


# RequirementNotMet

orgId: NCBI__GCF_004571175.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


