# Candidate

orgId: NCBI__GCF_009910325.1
pathwayId: arg
stepId: argD'B
locusId: WP_160718999.1
sysName: ISALK_RS03310
desc: ornithine--oxo-acid transaminase
otherIds: SwissProt::P38021
curatedIds:
CharProtDB::CH_002469,SwissProt::P77581,ecocyc::SUCCORNTRANSAM-MONOMER,metacyc::SUCCORNTRANSAM-MONOMER


orgId: NCBI__GCF_009910325.1
pathwayId: his
stepId: hisA
locusId: WP_160718993.1
sysName: ISALK_RS03290
desc: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
curatedIds: reanno::Putida:PP_0292
hmmId: TIGR00007
hmmDesc:
hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (EC 5.3.1.16)


orgId: NCBI__GCF_009910325.1
pathwayId: lys
stepId: dapB
locusId: WP_160718340.1
sysName: ISALK_RS00835
desc: 4-hydroxy-tetrahydrodipicolinate reductase
hmmId: TIGR00036
hmmDesc: dapB: 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8)
curatedIds:
CharProtDB::CH_002128,SwissProt::P04036,ecocyc::DIHYDROPICRED-MONOMER,metacyc::DIHYDROPICRED-MONOMER


orgId: NCBI__GCF_009910325.1
pathwayId: pro
stepId: proC
locusId: WP_160718241.1
sysName: ISALK_RS00320
desc: pyrroline-5-carboxylate reductase
hmmId: TIGR00112
hmmDesc: proC: pyrroline-5-carboxylate reductase (EC 1.5.1.2)
curatedIds:
CharProtDB::CH_024367,SwissProt::P0A9L8,ecocyc::PYRROLINECARBREDUCT-MONOMER,metacyc::PYRROLINECARBREDUCT-MONOMER


# RequirementNotMet

orgId: NCBI__GCF_009910325.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


