# Candidate

orgId: NCBI__GCF_017352195.1
pathwayId: pro
stepId: proC
locusId: WP_207235354.1
sysName: JYG23_RS09060
desc: pyrroline-5-carboxylate reductase
hmmId: TIGR00112
hmmDesc: proC: pyrroline-5-carboxylate reductase (EC 1.5.1.2)
curatedIds:
CharProtDB::CH_024367,SwissProt::P0A9L8,ecocyc::PYRROLINECARBREDUCT-MONOMER,metacyc::PYRROLINECARBREDUCT-MONOMER


# RequirementNotMet

orgId: NCBI__GCF_017352195.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


