# Candidate

orgId: NCBI__GCF_900639915.1
pathwayId: chorismate
stepId: tpiA
locusId: WP_133127582.1
sysName: E1O52_RS04850
desc: triose-phosphate isomerase
hmmId: TIGR00419
hmmDesc: tpiA: triose-phosphate isomerase (EC 5.3.1.1)
curatedIds:
BRENDA::P0A858,CharProtDB::CH_024675,SwissProt::B1XB85,SwissProt::P0A858,ecocyc::TPI-MONOMER,metacyc::TPI-MONOMER


orgId: NCBI__GCF_900639915.1
pathwayId: cys
stepId: cysE
locusId: WP_133128066.1
sysName: E1O52_RS07335
curatedIds: BRENDA::A0A0H2UNY1
desc:
bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU

otherIds:
BRENDA::P0ACC7,CharProtDB::CH_014350,SwissProt::P0ACC7,ecocyc::NAG1P-URIDYLTRANS-MONOMER,metacyc::NAG1P-URIDYLTRANS-MONOMER


orgId: NCBI__GCF_900639915.1
pathwayId: his
stepId: hisH
locusId: WP_133127056.1
sysName: E1O52_RS02075
desc: imidazole glycerol phosphate synthase subunit HisH
hmmId: TIGR01855
hmmDesc: hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (EC 2.4.2.-)
curatedIds:
CharProtDB::CH_024511,SwissProt::P60595,ecocyc::GLUTAMIDOTRANS-MONOMER,metacyc::GLUTAMIDOTRANS-MONOMER


orgId: NCBI__GCF_900639915.1
pathwayId: ile
stepId: ilvD
locusId: WP_133127841.1
sysName: E1O52_RS06210
desc: phosphogluconate dehydratase
curatedIds: curated2:A8AB39
otherIds:
CharProtDB::CH_024239,SwissProt::P0ADF6,ecocyc::PGLUCONDEHYDRAT-MONOMER,metacyc::PGLUCONDEHYDRAT-MONOMER


orgId: NCBI__GCF_900639915.1
pathwayId: trp
stepId: trpD_1
locusId: WP_133127821.1
sysName: E1O52_RS06110
desc: glutamine-hydrolyzing GMP synthase
curatedIds: curated2:O28670
otherIds:
BRENDA::P04079,CharProtDB::CH_003303,SwissProt::P04079,ecocyc::GMP-SYN-MONOMER,metacyc::GMP-SYN-MONOMER


orgId: NCBI__GCF_900639915.1
pathwayId: trp
stepId: trpE
locusId: WP_133127249.1
sysName: E1O52_RS03100
desc: aminodeoxychorismate synthase component I
curatedIds: curated2:O66849
otherIds:
CharProtDB::CH_002963,SwissProt::P05041,ecocyc::PABASYN-COMPI-MONOMER,metacyc::PABASYN-COMPI-MONOMER


# RequirementNotMet

orgId: NCBI__GCF_900639915.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


