>AO353_04175 FitnessBrowser__pseudo3_N2E3:AO353_04175
MTTASQQPSLSSQCMAEFLGTALLIFFGTGCVAALKVAGASFGLWEISIIWGIGVSMAIYLTAGVSGAHLNPAVSIALCIFADFEKRKLPLYIFSQVAGAFCAALLVYTLYSNLFFDFEQTHQMVRGTQASLELASVFSTFPNPALSTAQAFLVEVIITAILMGVIMSLTDDNNGLPKGPLAPLLIGLLIAVIGSSMGPLTGFAMNPARDFGPKLMTFFAGWGEISFTGGRDIPYFLIPIFAPILGACLGAAAYRGLIARHLPIAIPATKDAEPAIDGKARIS
>ecocyc__GLPF-MONOMER glycerol facilitator (Escherichia coli K-12 substr. MG1655)
MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEISVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAALVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILMGLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAGWGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSEQKASL
>biolip__1fx8A Crystal structure of the e. Coli glycerol facilitator (glpf) with substrate glycerol
TLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEISVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAALVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILMGLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAGWGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHL
>SwissProt__B1VB61 Propanediol uptake facilitator PduF (Citrobacter freundii)
MNDSLKAQCIAEFLGTGLFLFFGIGCLSALKVAGASLGLWEICIIWGLGISLAVYLTAGISGAHLNPAITIALWLFACFPGRKVLPYTVAQVAGAFGGALLAYLLYGSLFTEYESAHQMVRGSLESLHLASIFSTYPAAALSVWQAALVEVVITSILMGMIMALTDDGNGVPKGPLAPLLIGILVAVIGASTGPLTGFAMNPARDFGPKLFAWMAGWGDVAMTGGRDIPYFIVPIVAPIIGACAGAAIYRYLIGKNLPCNTCKLDENES
>SwissProt__P37451 Propanediol uptake facilitator PduF (Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720))
MNDSLKAQCGAEFLGTGLFLFFGIGCLSALKVAGASLGLWEICIIWGLGISLAVYLTAGISGGHLNPAVTIALWLFACFPKQKVLPYIIAQFAGAFGGALLAYVLYSSLFTEFETAHHMVRGSVESLQLASIFSTYPAAALNVWQAALVEVVITSILMGMIMALTDDGNGIPKGPLAPLLIGILVAVIGASTGPLTGFAMNPARDFGPKLFTWLAGWGNMAMSGGREIPYFIVPIVAPVIGACAGAAIYRYFIGKNLPCNRCEL
>metacyc__ENSG00000103569-MONOMER aquaporin-9 (Homo sapiens)
MQPEGAEKGKSFKQRLVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGAVIGGLIYVLVIEIHHPEPDSVFKTEQSEDKPEKYELSVIM
>SwissProt__Q96PS8 Aquaporin-10; AQP-10; Aquaglyceroporin-10; Small intestine aquaporin (Homo sapiens (Human))
MVFTQAPAEIMGHLRIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVGTATYQLLVALHHPEGPEPAQDLVSAQHKASELETPASAQMLECKL
>biolip__6f7hC Crystal structure of human aqp10
IRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVGTATYQLLVALHH
>SwissProt__G5CTG7 Aquaporin-10; AQP-10 (Milnesium tardigradum (Water bear) (Tardigrade))
MADAPTYIRQSTTGTATTAPTTMPVHPDTTYYKTTTTTVSDAPRAIADVNDDNHDNYDETTGLRSGEKKTRPLVTSTTAPIDAGRMTLGQKISRWTRIGSDLAREALAEFLGSFILIVFGNGVVAQVVLSRGAHGNFLSINIGYGLAVAFGVYIAGGISGGHLNPAVSLAFAALGKLPWRKLPVYMFAQYAGCICASAIVHAIYYDALNNYDGGNRTRGDTWQSTAGIHASYPQEFLYWQTGLADQIFATSFLMIGILALTDNRNTGPPGGVVPILVGCLVMAIGLAYGFNCGYPINPARDMGPRLFTLMAGWGSRTFSNYNPYIFNDYYQRIPYWFWIPVVGPHLGALLGAAIYFFFIGNHWPTLHRNVLELQVGHRDNSDDIELLAAKSRRPIEVVTTTETTRERRT
>SwissProt__Q8R2N1 Aquaporin-3; AQP-3; Aquaglyceroporin-3 (Mus musculus (Mouse))
MGRQKELMNRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILVAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYALAQTLGAFLGAGIVFGLYYDAIWAFANNELFVSGPNGTAGIFATYPSGHLDMVNGFFDQFIGTAALIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSEVFTTGRHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSTEEENVKLAHMKHKEQI
>SwissProt__A9Y006 Aquaporin-3; Aquaglyceroporin-3 (Sus scrofa (Pig))
MGRQKELVTRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILVAGQVSGAHLNPAVTFAMCFLAREPWIKLPVYTLAQTLGAFLGAGIIFGLYYDAIWAFANNQLIVSGPNGTAGIFATYPSGHLDMVNGFFDQFIGTASLIVCVLAIVDPNNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTAIAGWGSEVFTTGRHWWWVPIASPLLGSIAGVFVYQLMIGCHLEPPPPSTDEENVKLSQVKHKE
>SwissProt__P47862 Aquaporin-3; AQP-3; 31.4 kDa water channel protein; Aquaglyceroporin-3 (Rattus norvegicus (Rat))
MGRQKELMNRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLAILVAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWAFAGNELVVSGPNGTAGIFATYPSGHLDMVNGFFDQFIGTAALIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSEVFTTGQNWWWVPIVSPLLGSIGGVFVYQLMIGCHLEQPPPSTEAENVKLAHMKHKEQI
>SwissProt__Q92482 Aquaporin-3; AQP-3; Aquaglyceroporin-3 (Homo sapiens (Human))
MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHKEQI
>SwissProt__P56627 Aquaporin-9; AQP-9; Aquaglyceroporin-9 (Rattus norvegicus (Rat))
MPSEKDGAKKSLMQRLALKSRIAKETLSEFLGTFIMIVLGCSSIAQAVLSRERFGGIITINIGFASAVVMALYVTFGISGGHINPAVSFAMCAFGRMEWFKFPFYVGAQFLGAFVGAATVFGIYYDGLMAFAGGKLLVVGENATAFIFATYPAPFISTPGAFVDQVVSTMFLLLIVFAMFDSRNLGVPRGLEPVVIGLLIIVLSCSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFTVGNNFWWIPVVGPMIGAFLGGLIYILFIQMHHSKLDPDMKAEPSENNLEKHELSVIM
>TCDB__Q6IRR9 Basolateral Aqp3 of 292 aas and 6 TMSs in the frog urinary bladder (Xenopus laevis)
MGSQKDFVNKCNQMLRLRNKLLRQALSECLGTLILVMFGCGSVAQVVLSKGSHGQFLTVNLAFGFAVMLGILISGQVSGGHLNPAVTFALCILAREPWIKFPVYSIAQTLGAFLGAGIVYGLYYDAIWFFANDQLYVTGENGTAGIFTTFPSEHLTLMNGFFDQFIGTAALIVCVLAIVDPNNNPIPRGLEAFTVGFVVLVIGTSMGFNSGYAVNPARDFGPRLFTSLAGWGTEVFWAGNQWWWVPIVSPLLGSFAGVLVYQLMIGCHIEPAPQSTQQENIKLADVKNKDRL
>SwissProt__A0A384JSZ0 Aquaglyceroporin-9 (Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea))
MEGGLRSPLNRAVRMAKYLLDSCIGMLPYPKQRCESFNVVDLLSTCSFYKAVSLKNLKLHIEQHPSFANPSLSHISKFAFTELPFHAFTFSIPKMSLDKQESPIPIVSNDKNIGIFESQNSSPNLSSHESTLDGNNMHTVSSEGSGAYAEHGPGIDHKIPQELEIQSKPDLLWSRVRHTMREPFSEFFGVFILILFGDGVVAQVVLSSGERGSYQSISWGWGIGVMLGVYASGVSGAHINPAVTFANCIFRKFPWRKFPIYMLAQVLGAMCASGVVYANYKSAIDMFEGGNNIRTVGLNTSSAGIFCTYPAPFMTKTGQFFSEFVASTILMFCIYALQDNGNLGSGNLTPLGLFFVIFGIGACFGWETGYAINLARDFGPRLMSYFLGYGHEVWSAGNYYFWVPMVAPFIGCLFGGWLYDVFIFTGESPINTPWMGLKRLMPGGLGSKKVDSKV
>SwissProt__B0D4E4 Aquaporin Lacbi1:247946 (Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor))
MKLTISHHKCAIRKVMAEFVGVALLVIFGAGTACQVVLSTNPSSFLSINFGWAIGIATGAWVSAGISGGHINPAITIAMATYRGFPWREVPGYIFAQALGGFVGAALVYANYFHAIDIFEGGHIRTQATASLFATFALPYMTQASCFFSEFLATAVLFIVFLALNDKHNGALTNGLLPFALFILFIGLGASLGMQTGYAVNPARDFGPRLFLAMAGYGKAVFNYRRQYWIWAPIIAPILGAQAGGLLYDTSIYNGDDSPIKWR
>SwissProt__O54794 Aquaporin-7; AQP-7; Aquaglyceroporin-7 (Mus musculus (Mouse))
MAPRSVLETIQSVLQKNMVREFLAEFLSTYVMMVFGLGSVAHMVLGENSGSYLGVNLGFGFGVTMGVHVAGGISGAHMNAAVTFTNCALGRMTWKKFPVYVLGQFLGSFSAAATTYLIFYGAINHFAGGDLLVTGSKATANIFATYLPEYMTLWRGFLDEAFVTGMLQLCLFAITDKKNSPALQGTEPLVIGILVTVLGVSLGMNSGYAINPSRDLPPRLFTFIAGWGKQVFRAGNNWWWVPVVAPLLGAYLGGIVYLGLIHPSIPQDPQRLENFTARDQKVTASYKNAASANISGSVPLEHF
>SwissProt__P56403 Aquaporin-7; AQP-7; Aquaglyceroporin-7 (Rattus norvegicus (Rat))
MAGSVLENIQSVLQKTWVREFLAEFLSTYVLMVFGLGSVAHMVLGERLGSYLGVNLGFGFGVTMGIHVAGGISGAHMNAAVTFTNCALGRMAWKKFPIYVLGQFLGSFLAAATTYLIFYGAINHYAGGELLVTGPKSTANIFATYLPEHMTLWRGFVDEVFVTGMLQLCIFAITDKLNSPALQGTEPLMIGILVCVLGVSLGMNTGYAINPSRDLPPRFFTFIAGWGKKVFSAGNNWWWVPVVAPLLGAYLGGIVYLGLIHAGIPPQGS
>SwissProt__B0D4J9 Aquaporin Lacbi1:317173 (Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor))
MSGQHQITEQSSRNPLSRVSTLLPEKPLSPTSTYAGTQKHPEAPRQSSFLIQLQNIRNAIRKPMAEFFGVALLIIFGAGSACQVVLSTNPDVASSARGSFLSINFGWAIGIAMGVWVSGGISGGHINPAITIAMATYRGFPWRKVPSYILAQVLGGVVGAGLVYANYIHAIDIFEGGHHIRTQATASLFATYALPYMTQASCFFSEFLATAVLSMMVFALTDKRNHSPTNGLLPFALFILFVGLGASLGMETAYALNPARDFGPRLFLAMAGYGKALFNYRSQYWLWAPIIAPVLGAQAGGLLYDTFLNDGDNSPIKWRCASSQEHQLAEVV
>SwissProt__I1Z8E9 Aquaporin-7-1 (Laccaria bicolor (Bicoloured deceiver) (Laccaria laccata var. bicolor))
MSGQHQITEQPSGNPLSRTSTLIQEKPLTPTSSHAETQKHLEAPRQSSFLIQLQDIRHAIRMPMAEFFGVALLIIFGAGSACQVVLSTNPNVASSDRGSFLSINLGWAIGIAMGAWVSGGISGGHINPAITIAMATYRGFPWRRVPSYIFAQVLGGVVGAALVYANYIHAIDIFEGGRHVRTQATASLFATYALPYMTQVSCFFSEFLATAVLSMMVLALTDNRNGAPTNGLLPFALFVLFIGLGASLGMETAYALNPARDFGPRLFLAMSGYGKALFNYRSQYWLWAPIIAPVLGAQAGGLLYDTFLYDGDNSPIKWRRASSQECQLAEVV
>SwissProt__I3W9F7 Aquaglyceroporin-2 (Rhizophagus irregularis (Arbuscular mycorrhizal fungus) (Glomus intraradices))
MADERGPINKSGPSSTYGATENNGESGGTRGAPATEDVIVIQDSGWYYIKFRFKEPFAEFLGTFILVAFGVGAIAQTVLSKGATGNWITIALGFGLGLALGIAVSGHYSGGHLNPAVTITLAIYRKFPWVKVPVYITAQVLGAFVAAAVIYLNYLPAIYNFAGDKRDVIGANATAGIFATYPQPFMSIGGAFFSEALGTFFLLFVILAMTDERNVPTTRIVAPITIGLTLTAIAISLGFETGFSLNAARDFGPRLFTFFIGYGVEVFTAYKFYFWIPLVAPIVGGLVAGFVYDSLLYWGEKSFLNKNVHHEHRAVA
>metacyc__ENSG00000165269-MONOMER aquaporin-7 (Homo sapiens)
MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
>TCDB__F6QEC2 Aquaporin/glycerol facilitator of 294 aas and 6 TMSs (Xenopus tropicalis)
EKPKRQKKKIKFKHKIALKNSLAKETLSEFFATCLLIILGCGCVATSVLSNTSDAYLTNNLGFAMAVTIAVYVSGGVSGGHINPAVSFAMCLTGRLKWAKFPFYVSAQFLGAIAGSAAVFGIYYDALYNYTGGILTVDGPNATAYIFATYPKPYLSIMGGFVDQVMSTALLLIGVLAIFDNKNLGTPKGLEPIAVGLLILLLGLSLGMNSGCAMNPARDLGPRIFTAMAGWGMEVFTSGNSWWWVPVVGPMLGAAIGAFIYVLCIEAHFSDDMEDVHNSQEADHYEKQELTSMA
>SwissProt__I1Z8F0 Aquaporin-7-2 (Laccaria bicolor (Bicoloured deceiver) (Laccaria laccata var. bicolor))
MSGQHQITEQPSGNPLSRTSTLIQEKPLTPTSSHAGTQKQPEAPRQPTFLIQLQNIRHAIRKPMAEFFGVALLIIFGAGSACQVVLSTNPDVASSARGSFLSINFGWAIGIAMGVWVSGGISGGHINPAITIAMATYRGFPWCKVPSYILAQVLGGVVGAALVYANYIHAIDVFEGGHHIRTEATASLFATYALPYMTQASCFFSEFLATAVLSMMVFALTDKRNHSPTNGLLPFALFILFVGLGASLGMETAYALNPARDFGPRLFLAMAGYGKALFNYRSQYWLWAPIIAPVLGAQAGGLLYDTFLNDGDNSPIKWRCASSQEQQLAEVV
>biolip__8c9hA Aqp7_inhibitor
QEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGS
>PDB_6n1g_A Crystal structure of aquaglyceroporin aqp7
KMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRK
FPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITD
QENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGII
YLVFIGSTI
>SwissProt__I1Z8E7 Aquaporin-5 (Laccaria bicolor (Bicoloured deceiver) (Laccaria laccata var. bicolor))
MAEFVGVALLVIFGAGAACQVILSTNPGVSPSERGSFLSINFGWAIGIATGAWVSTGMSEGHINPAITIGMATYRGFPWREVPGYIFGQVLGGFVGAALVYANYFHAIDIFEGGHRTQATASLFATFALPYMTQASCFFSEFLATAVLFIVFLALNDKHNGALTNGLLPFALFILFIGLGASLGMQTGYAVNPARDFGPRLFLAMAGYGKAVFNYRRQYWIWAPIIAPILGAQAGGLLYDTFIYNGDDSPIKWR
>SwissProt__G5CTF9 Aquaporin-2; AQP-2 (Milnesium tardigradum (Water bear) (Tardigrade))
MCISEGKMDWRSWLRKKFQVRSQLLRGCMAEFLAVFVLMVFTEGCSASAIFTHRRNDLLFAAFGSGLAVTMAVYVAGGVTGAFLNPAIAVAFSVLGKLPWKNCFCYMIAQYLGAFLASLAIYAQYYDALNIFDGGHRQVLGDNGTAQIWSTYPQAFLSPQGAFVDQVFGTALLIIVVLSMVDKKNWKPQNGYFPIAIGLLIVVLDISLAYNAGAALNPSRDLAPRLFTYVAGYGTETFSVKGYTWFFVPVVGSHAGAIVGAVIYQLFIGAQWPQDDLDDSNSVSSMSIHEKNFSLAKRKNTRNFNLDITRDFKERNGISTVLY
>TCDB__Q6ZXT4 Aquaporin 1 (permeable to water, glycerol, dihydroxyacetone and urea) (Trypanosoma brucei brucei)
MSDEKINVHQYPSEADVRGLKARNGGACEVPFEENNEPIPNRSANPQEKNENELVGDNADNEAHDAVDVNYWAPRQLRLDYRNYMGEFLGTFVLLFMGNGVVATTILDKDLGFLSIAFGWGIAVTMGLYISLGISCGHLNPAVTLANAVFGCFPWRRVPGYIAAQMLGAFVGAACAYGVYADLLKQHSGGLVGFGDKGFAGMFSTYPREGNRLFYCIFSEFICTAILLFCVGGIFDPNNSPAKGHEPLAVGALVFAIGNNIGYASGYAINPARDFGPRVFSAILFGSEVFTTGNYYFWVPLFIPFLGGIFGLFLYKYFVPY
>SwissProt__I1RHJ1 Probable aquaglyceroporin-2 (Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum))
MPISTINDSISESSVHKSSIPTKVEMSQNEKYSEAPSEAPTIPPPPEQYAWSRIRENCQDAFSEFFGTFVLLLFGDGVVAQVVLSRGTKGDYQSISWGWGLGVMLGVYVGGKSGGHLNPAVTLANCLFRGHPWRKFPIYAVAQVLGAMAAAAVVYGNYKSAIDAYEGGPGIRTVIGENATAGVFCTYPAEFMTRTGMFFSEFIASTILQFVIFAMADSANIGAGPLMPLGLFFLIFGIGACFGWETGYAINLARDFGPRLVSYMLGYGSEVWSAGGYYFWIPMVAPFFGCAFGGFLYDVFIYTGPSPINTPGMGFGRLVSPRRSTWSNTYNANSPV
>SwissProt__B0DLE4 Aquaporin Lacbi1:391485 (Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor))
MDDKFDDDALPNSKTTPEDYGDKLAEYDYTNTFPNTWMRLREPFREYIAEFVGVAVLIIFGVGADCQVVLSANTGVAPSPKGDYLSLNCGWAIGTAMGVWISGGISGGHINPAVTLALMAWRGFPWWKVPGFIFAQLLGGIVGAGLVYVNYIHAIDIVEGGRHIRTLDTAGLFATYAADYMTNVSCFFSEFLATAVLIVVIHAMNDKRNAPPPAGLAPLVLFFLILGIGASLGMETGYAINPARDLGPRMLTAMVGYGRQVFAFRNQYWIWCPVIAPFLGAQVGTIFYDLFFYKGQDNVFGRLGSHIHISPA
>ENA__CAR66115.1 water-specific aquaporin (Rhipicephalus sanguineus)
MLDSVKIKNALVREVLAELLGTFVLVLFGNTVLAVVAFDRAPNLGYAAAFWGWALALTLGVLVAGGVSGAHLNPAVTVAVTTVGKFPWRKIVPYMVAQYIGAFLASVILFITYRGALDNYDGGVRAVTGSNATAGIFASYPQEFVSTGNGLVDQIVGTALLVLAILAITDSRNMAVPQGVQPLFIGLALGALILCFGYNCGAPLNPARDLGPRVFTAMAGWGVEVFSYRDYNWFWVPIVGPHIGAIVGAWLYTLAVELHWPGSSYDMDSGNTVSAKDAPRFQLANQNEAIF
>SwissProt__I1Z8E8 Aquaporine-6 (Laccaria bicolor (Bicoloured deceiver) (Laccaria laccata var. bicolor))
MDDKFDDDALPNSKTTAKDYEDKLPEYDYTTTFPNTWMRLREPFREYFAEFVGVAVLIIFGVGADCQVVLSANTGVASSPKGSYLSLNCGWAIGTAMGVWISGGISGGHINPAVTLAMATWRGFPWWKVPGFIFAQLLGGIVGAGLVYVNYIHAIDIVEGGRHIRTLDTAGLFATYAADYMTNLSCFFSEFLATAVLIIVIHAMNDKRNTPPPAGIVPFVLFFLILGIGASLGMETGYAINPARDLGPRMLTAMVGYGRQVFAFRNQYWIWCPVLAPFLGAQVGTIFYDLFFYKGQDNVFGRLGSHIHISPA
>SwissProt__I1CR68 Aquaporin-1 (Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar))
MASTHSSLTTVQNNANNKSNRTLNTERRLSMESSVFTLYNKAADELDTSQRSAFQACHREFLAEFIGTVILVLLTCGFCAEQTLHIEESKSWLTSSFGSGLSVLIGICVSGHVSGAHLNPAVTIAFCIFSGFPIRKVPSYITAQLLGAFAGAALLYIIIEPAIVQFDGGQRYILGEKSTAGIFGTYPPLYVGIGSAIASEIMGTAMLLLVIMVTGHPNNLPYKSAQGAMIALGITTISLCIGYTSGFSLNPARDFGPRLFTAIAGWGFDVFKVYHYYALVPMFAPILGGLVGLMLMMPFSFLSVRA
>SwissProt__G5CTG5 Aquaporin-8; AQP-8 (Milnesium tardigradum (Water bear) (Tardigrade))
MSTAESRNHYKEVPTIEHYSEAIGITNRKKMDWRGWLRKSTLVRSQLIRGCMAEFLAVFVLMVFIEGSAATAIFTNRRQDILFGSISSGLGVAMAVYVAGGVSGAFLNPAVALAFAVLGKLSWKNCIFYMISQYLAAFVASCTMFAYLYEALNNFDGGERQMFGPNGTAHIWSTYPQPFLSPHTAFADQVFCTAILLIVVLAMCDSKNWKPHNGFLPIAIGLLIITISCTLSYNAGAAMNPSRDLAPRFFSYLAGYGTEPFGVKGYTWFFVPVLGSHCGAIIGGAIYQLFIGGQWPDDTSDTNSVSSMSYNEDNSTLTKRKQVSNIVHDSKGAKGSSTAPVN
>SwissProt__P43549 Aquaglycerol porin AQY3; Aquaporin-3 (Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast))
MSYESGRSSSSSESTRPPTLKEEPNGKIAWEESVKKSRENNENDSTLLRRKLGETRKAIETGGSSRNKLSALTPLKKVVDERKDSVQPQVPSMGFTYSLPNLKTLNSFSDAEQARIMQDYLSRGVNQGNSNNYVDPLYRQLNPTMGSSRNRPVWSLNQPLPHVLDRGLAAKMIQKNMDARSRASSRRGSTDISRGGSTTSVKDWKRLLRGAAPGKKLGDIEAQTQRDNTVGADVKPTKLEPENPQKPSNTHIENVSRKKKRTSHNVNFSLGDESYASSIADAESRKLKNMQTLDGSTPVYTKLPEELIEEENKSTSALDGNEIGASEDEDADIMTFPNFWAKIRYHMREPFAEFLGTLVLVIFGVGGNLQATVTKGSGGSYESLSFAWGFGCMLGVYVAGGISGGHINPAVTISMAIFRKFPWKKVPVYIVAQIIGAYFGGAMAYGYFWSSITEFEGGPHIRTTATGACLFTDPKSYVTWRNAFFDEFIGASILVGCLMALLDDSNAPPGNGMTALIIGFLVAAIGMALGYQTSFTINPARDLGPRIFASMIGYGPHAFHLTHWWWTWGAWGGPIAGGIAGALIYDIFIFTGCESPVNYPDNGYIENRVGKLLHAEFHQNDGTVSDESGVNSNSNTGSKKSVPTSS
>SwissProt__I1CS06 Aquaporin-2 (Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar))
MSLRDDLTINERDPLLSSFDQRQEYNTSNNTYKVNNNSNEPSVLTLYNSDELGTSQRSSYQKFVRRSQEFKMQHREFLAEFIGTLILVLLTCGFCAEQTLNIEKSKSWLTSSLGSGLSVLIGICVAGHVSGGHLNPAITIAFWVFSGFPIRKVPMYITAQLLGAFSGAALLYSIVEPAISQFDHGKRQILGELGTAGIFGTYPPLYVGTGSAVASEVVGTAMLLLVVMVTGHPNNLPFRTAQGAMIALGVTTISLCIGYTSGFSLNPARDFGPRLFTAVAGWGIDVFTVHHYYALVPMFAPILGGLAGGFIYTVFID
>SwissProt__G5CTG4 Aquaporin-7; AQP-7 (Milnesium tardigradum (Water bear) (Tardigrade))
MAHNEKDPSSVEPIKRKRFSNEYVRLFLAEFLGTFILIVFGCGTVAVTILSKHQSQDFFSVNVGFFLGIAFGVFIAGGVSGGHLNPAVTLAFAVINKCKWRKVPVYMAAQYLGAWVGSAILTAIYYDALHNHDQGNRTIETAGIYASYPQEFLTWQGGLADQIFATLLLMMGILALTDERNMVGPTGRAYVPLLVGLLVLAIGLAFGFNCGYPINPARDFGPRLFTAMAGWGTQVFSEPRGTYNWWWIPIIGPHVGAIIGALAYNFFIGYHWPKERDDVQLQSPSSPIVIVKNDAYQPLRPSRSVYSEELRITTS
>TCDB__C4PYI6 Aqp1 of 304 aas and 6 TMSs; the most abundant transmembrane protein in the tegument of Schistosoma mansoni. This protein is expressed in all developmental stages and seems to be essential in parasite survival since it plays a crucial role in osmoregulation, nutrient transport and drug uptake (Schistosoma mansoni)
MVSCSEKYAHKQHIVADRLRLTSSPLVRACLGEFMGSIILMIFGSGVLAQVILGDHGKHAHGTFISVSLGWGFAVYMAVMFSGQCGSGHCNPAVTLAAAVVGKLPFRRIPFYTFFQILGAFLGSLVVFALYREKIIEYAKLNDNGALLLNTTGGIFVTNPSASHLTCFLDQVMGTALLTAGAFAITDPNGWKIPDYLHPLHLAFLVYAIVGCFALNAGAALNPARDLGPRLMIFIFGWGNKAFSGANYFFWIPIVGPYIGAVIGGILYEMTIGIHLDRKSDFVVDVDYDDSHRDGKKLVAYSSP
>TCDB__Q6Q1Q6 Major aquaglyceroporin, LmAQP1: transports water, glycerol, methylglyoxal, trivalent metalloids such as arsenite and antimonite, dihydroxyacetone and sugar alcohols. Also takes up the activated form or the drug, pentostam (Leishmania major)
MHEEEEDQHESKRNFMSQNRWPLYRYRWRLREYVAEFFGTFFLVTFGTGVVATTVFHGGTTAMYQSNSSYLAITFGWAFGLAISLFLSMAVSGGHLNPAVTLANCVFGTFPWVKLPGYFLAQFLGGFVGAANTYVLFKSHFDEAEKRLLLNETMASKYGGIFATYPNVANTYAVWSEVFNTMALMMGILAITDARMTPAVDYKPVAIGLLLFVIGIASGINSSYGLNPARDLSPRILSAMLWGSEPFTLHSYYFWIPLVVPFVGALFGMFLYVFFIIPPSC
>SwissProt__A0A384JPP3 Aquaglyceroporin-4 (Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea))
MADEEIKPTSSIEAGGGQNNEHEHGMTSLPNLPSTREETPRELSPVAGSSRAQSTGEQGVKPLKRFDTLPTRRSQLSPDTRRRGRTLTGQVPQDNDLSSRRQVFRRGTSVLSGESGDRMRSIPERGPVPPTTERESRPSGVSDRTQASGLRPRRSTTSRQRGPSIRRRPTVALEAVTSGADVGGGDNFTLAGPAPIETSAQNQPYVDPGYAHLNPAYVQPENVRPVWGLAKPLPRVVRPGMIPSRTEINMAQQQQQQQQQQPQNQADVDLEQGRIEPTLKLSRISTALQNARQQRENNLMEAHGLVSPTNLQTTASRQEPLTAPSQVIEEEDLADKPTNTDTTSPERPPTRPPLSFDGRPSQTSQNSQNEPFPALSDHDDQESVATEVAGPDDLDGEWIGQEIPLVAYDPNYDDEIHNLHTHWSVIRLRFREPLAELLAVTCQLTLGFCADLVVVTSGKNASPAGNEATTDWAWGLASMLGIYIAGGISGAHLNPAISIMLWIYRGFPLRKVPMYVLAQILGAFIAALISFGLYQTNIVEYGGTDLKTSDTMGAFITYPRYPWINASTSFFTEFVGTAILAVAVLALGDDMNAPPGAGMSAFILGLVITVLSMAFGYNTGAALNPSRDLGPRLALAALGYGKDLFTDVYWIWGNWCAPILGAIFGAFLYDAAIFAGGESPVNYPRKRIKRAGHKWRKKWGVRLRKMKPAKKGEDEAYRRWKESQ
>TCDB__Q8WPZ6 Aquaglycerolporin, Aqp (high permeability to ammonium, methylamine, glycerol and water) (Beitz et al., 2004) NH4+/NH3+CH3 transporter (Plasmodium falciparum)
MHMLFYKSYVREFIGEFLGTFVLMFLGEGATANFHTTGLSGDWYKLCLGWGLAVFFGILVSAKLSGAHLNLAVSIGLSSINKFDLKKIPVYFFAQLLGAFVGTSTVYGLYHGFISNSKIPQFAWETSRNPSISLTGAFFNELILTGILLLVILVVVDENICGKFHILKLSSVVGLIILCIGITFGGNTGFALNPSRDLGSRFLSLIAYGKDTFTKDNFYFWVPLVAPCVGSVVFCQFYDKVICPLVDLANNEKDGVDL
>biolip__3c02A X-ray structure of the aquaglyceroporin from plasmodium falciparum
SYVREFIGEFLGTFVLMFLGEGATANFHTTGLSGDWYKLCLGWGLAVFFGILVSAKLSGAHLNLAVSIGLSSINKFDLKKIPVYFFAQLLGAFVGTSTVYGLYHGFISNSKIPQFAWETSRNPSISLTGAFFNELILTGILLLVILVVVDENICGKFHILKLSSVVGLIILCIGITFGGNTGFALNPSRDLGSRFLSLIAYGKDTFTKDNFYFWVPLVAPCVGSVVFCQFYDKVICPLVDLA
>SwissProt__I1RIY3 Probable aquaglyceroporin-4 (Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum))
MAGTQDQSQDYFSKPTTPSTPGQAHLGNVANRIPSTIPDRESGTERAKSTHSRHRVLHGLPSTFMSYMSRRPVASSRGFSRVSSEGTASRPTAPQHSSHFHHYAPAEDGYYQENPWFGEADKKPIFSLGKPLPHKVRRKVLKPVRPDGKVDEEMAIVKEETTNEPHPGYASRTTSGQPYRVETQSSLPSRDIQRQQSRTTAAGVAHNDRRNDAGQPVFEYIPGEATPTPGHRDPASRVQSKQDNGHSPPDFKVDGEPLGHQEKPCVESGDTNANEMRNWWARLRARHPEPLAEFLATAVAIFLGLTGTLSVNLSATQSQPYGTYETSCWAWGFAWMFGIYLGGGVSGAHMNPAISVSLSIFRGFPWRQCVIYVFVQFIASIVAGALAYAMYADSINHVDPDMTKMSMTFFSTPREWVTLKSAFFNQVVGSAIMMIAVFALGDDQNNPPGAGMHALVLGFLVTTLKFTLGYNIGSALNPASDFGPRVIAYAVGFRGDNVFHSGWWFYGPWAATLIGSLLGCTLYDGFVFVGSESPVNFRVDKRVKKLFN
>TCDB__P18156 Glycerol facilitator (Bacillus subtilis)
MTAFWGEVIGTMLLIIFGAGVCAGVNLKKSLSFQSGWIVVVFGWGLGVAMAAYAVGGISGAHLNPALTIALAFVGDFPWKEVPVYIAAQMIGAIIGAVIIYLHYLPHWKSTDDPAAKLGVFSTGPSIPHTFANVLSEVIGTFVLVLGILAIGANQFTEGLNPLIVGFLIVAIGISLGGTTGYAINPARDLGPRIAHAFLPIPGKGSSNWKYAWVPVVGPILGGSFGGVFYNAAFKGHITSSFWIVSVILVVVLLGLYVYTKSHSAKTLSNSKYI
>SwissProt__G5CTG1 Aquaporin-4; AQP-4 (Milnesium tardigradum (Water bear) (Tardigrade))
MSKVPPTDPFSHMLNGNLQQRIVKRDIDGEVPTERAVTDLASEKAHAIATHGEVVIQIQHSDTFGMDKEKNDWRSRAARMLYIESRLVREGLSESLAMFFFMSLLLGCAATARFTGNQNDPMLAAFYHGFSIIFAIYVAGGISGGLLNPAITFTIAFLGRLSWLRCLIYMSAQYFGAFIASAVVYLIYYDSLQNFSGANKVDETGANGTAGIWSTFPRPYLSLRGAIFNQIFCTMLLTIGFLSICDFRNSRPDKGMFPFAVGMLIMTVFLAFSYSAGAAMNPARDISPRLWTLIVGYGDEVFSYNNYKWFWIPWLFPYVGALLGGVIYEIFIGIHWPKDYANKHVTNRT
>SwissProt__G5CTG0 Aquaporin-3; AQP-3 (Milnesium tardigradum (Water bear) (Tardigrade))
MAISWRTWLKKTIHCDNSYVRTGLAEFLGTFLLVLLLNGMIITAHMSVRNADGTMAHPLNTAHLAFGGGLAVMVAVLVSGGISGAHLNPAVTTTMLVMGRLSPLKSLVYIFMQYMGAFFAASILYAVYFESILAYDYGERQVLGANGTAGWFATYPQEHISLVTQIFDAILGTGLLVMGIFAIIDPNNMAVPKGQIPLYVGFLISSLIFSFSYNAGAALNPARDLAPRLFLWVIGYGAEAFTARGHLWWLVPVIGPHVGGLLGGVTYQMFIGAHYQSDRKLKPATIMDEDDDTNATYNTITTTTHQKVYNGRRNFDESVPLKTVHA
>CharProtDB__CH_091784 aquaglyceroporin 2 (Trypanosoma brucei brucei)
MQSQPDNVAYPMELQAVNKDGTVEVRVQGNVDNSSNERWDADVQKHEVAEAQEKPVGGINFWAPRELRLNYRDYVAEFLGNFVLIYIAKGAVITSLLVPDFGLLGLTIGIGVAVTMALYVSLGISGGHLNSAVTVGNAVFGDFPWRKVPGYIAAQMLGTFLGAACAYGVFADLLKAHGGGELIAFGEKGIAWVFAMYPAEGNGIFYPIFAELISTAVLLLCVCGIFDPNNSPAKGYETVAIGALVFVMVNNFGLASPLAMNPSLDFGPRVFGAILLGGEVFSHANYYFWVPLVVPFFGAILGLFLYKYFLPH
>SwissProt__G5CTF8 Aquaporin-1; AQP-1 (Milnesium tardigradum (Water bear) (Tardigrade))
MQKMSEKPLYRAAENPTRNADRRAGRFEEEELISKTGRHPDMVIQFQDDADDQHTSHYEGNWRHYFHKKLHIKNRLIRDWLSESLAMFLFMSLLLGGAATAHFTGKQDDPMLTAVFHGFSAVFGIYVGAGVSGGIINPALTFAVALLGRVSWRKCLVLVSAQYFGSFIASAVVYLIYYESLQNYAKTADDNGEFLQKTAGIWSTFPKPYLSMTGAIFNQIFCTMLLSIGFLSISDHKNFRPTKGLFPFAVGLLIMTVFLAFSYSAGAAMNPARDLSPRLWSLIIGYGNEVFSHNDYKWFWIPWLFPYVGALFGAVMYQIFVGVHWPDKQSTKR
>biolip__8jy6A Structure of tbaqp2 in complex with anti-trypanosomatid drug melarsoprol
YRDYVAEFLGNFVLIYIAKGAVITSLLVPDFGLLGLTIGIGVAVTMALYVSLGISGGHLNSAVTVGNAVFGDFPWRKVPGYIAAQMLGTFLGAACAYGVFADLLKAHGGGELIAFGEKGIAWVFAMYPAEGNGIFYPIFAELISTAVLLLCVCGIFDPNNSPAKGYETVAIGALVFVMVNNFGLASPLAMNPSLDFGPRVFGAILLGGEVFSHANYYFWVPLVVPFFGAILGLFLYKYFLPH
>PDB_8jy8_A Structure of tbaqp2 in complex with anti-trypanosomatid drug pentamidine
YRDYVAEFLGNFVLIYIAKGAVITSLLVPDFGLLGLTIGIGVAVTMALYVSLGISGGHLNSAVTVGNAVFGDFPWRKVPG
YIAAQMLGTFLGAACAYGVFADLLKAHGGGELIAFGEKGIAWVFAMYPAEGNGIFYPIFAELISTAVLLLCVCGIFDPNN
SPAKGYETVAIGALVFVMVNNFGLASPLAMNPSLDFGPRVFGAILLGGEVFSHANYYFWVPLVVPFFGAILGLFLYKYFL
PH
>SwissProt__F9USY3 Glycerol uptake facilitator protein 2 (Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum))
MHGFLGEFLGTMVLIVFGVGSGAAMNLKGNYARHQNWTFICLAWGLAVTFGVYVAGQFGSDGHLNPAVTVGFALFGYLPMANVWPYLLGQFLGAFIGAVIVIIQYYPHFQAAKTAADGNQVGIFATGPAISNPVFNFLSETIATFFFIFVLLNLGNFTQGLKPLMVGLLIVVVGQTLGGTTGFAINPARDWAPRLAYTILPVPNKGLANWGYAWVPMFGPLLGGILAAGLETIIS
>TCDB__Q9C4Z5 Hg2+-inhibitable aquaporin, AqpM (transports both water and glycerol as well as CO2) (Kozono et al., 2003; Araya-Secchi et al., 2011). Its 3-d structure has been determined to 1.7 Å. In AqpM, isoleucine replaces a key histidine residue found in the lumen of water channels, which becomes a glycine residue in aquaglyceroporins. As a result of this and other side-chain substituents in the walls of the channel, the channel is intermediate in size and exhibits differentially tuned electrostatics when compared with the other subfamilies (Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133))
MVSLTKRCIAEFIGTFILVFFGAGSAAVTLMIASGGTSPNPFNIGIGLLGGLGDWVAIGLAFGFAIAASIYALGNISGCHINPAVTIGLWSVKKFPGREVVPYIIAQLLGAAFGSFIFLQCAGIGAATVGGLGATAPFPGISYWQAMLAEVVGTFLLMITIMGIAVDERAPKGFAGIIIGLTVAGIITTLGNISGSSLNPARTFGPYLNDMIFAGTDLWNYYSIYVIGPIVGAVLAALTYQYLTSE
>SwissProt__F9UTW9 Glycerol uptake facilitator protein 3 (Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum))
MMKDPLALQLLGEFLGTFILILLGDGVVAGVTLNKSKAQNAGWVAITLGWGFAVTMGVYASSFMSPAHLNPAVSLGMAVAGKFPWAYVIPYSAAQIAGGVIGGLVVWLHYYPHWQATKDAGAILGIFATGPGIRRYFWNFISEVIGTFVLVFGLLAFTKGQFTAGLNPIVVGILIIAIGLSLGGTTGYAINPARDLGPRIAHAVLPIANKGTSDWAYSWVPIAGPLVGGALGALLFNVLP
>biolip__2evuA Crystal structure of aquaporin aqpm at 2.3a resolution
MVSLTKRCIAEFIGTFILVFFGAGSAAVTLMIASGGTSPNPFNIGIGLLGGLGDWVAIGLAFGFAIAASIYALGNISGCHINPAVTIGLWSVKKFPGREVVPYIIAQLLGAAFGSFIFLQCAGIGAATVGGLGATAPFPGISYWQAMLAEVVGTFLLMITIMGIAVDERAPKGFAGIIIGLTVAGIITTLGNISGSSLNPARTFGPYLNDMIFAGTDLWNYYSIYVIGPIVGAVLAALTYQYLTS