>202770 FitnessBrowser__MR1:202770
MAMSLSAAPVAKQHFERTQLTVDRLSYAIGDKAVLNNIRVQFQPGSVTALLGPNGAGKSTLLKALCQEIPSAQGSIKLGHCQLVDWPRAELAKSLAVLPQHASLTFPFTVDEVVAMGLYPLTLSQKEGQQLVTKWLAEVGVLHLARRSYPTLSGGEKQRVQLARVLTQLSQSPFPPILLLDEPTSALDLAQQHKVLALAKNLAHKHAYTVIVVLHDLNQAARYSDRVIVLKQGEIVSEGTPNDALSIDIIRQVWDYEPEFIPAPQGDYPLIF
>TCDB__O68877 Hemin import ATP-binding protein HmuV, component of The heme uptake porter, PhuTUV (transports one heme per reaction cycle) (Pseudomonas aeruginosa)
MLRVENLSIRRGGKTVLEGLELELRPGEMLGVLGPNGAGKSTLLGALCGELEPAEGLVLLDERGLDDWPGVARAQRLAVLPQSSSLGFAFPVEAVVGFGRLPHSSGRERDVQIVAEALAAADASHLAGRSYLALSGGERQRVHLARVLAQLWPGEPGQVLLLDEPTSALDPLHQHTTLQAVHDFARRGASVLVILHDLNLAARYCDRLLLLQNGRPHLLGTPEEVLRPEPLRAVFGLEVLVQRHPERGHPLIVAR
>TCDB__Q93SS1 Hemin import ATP-binding protein hmuV, component of Heme uptake porter, HugBCD (Villarreal et al., 2008); also called HmuTUV (Plesiomonas shigelloides)
MRNLTLQRGRRQILSQLSLDLRAGELTVLLGPNGTGKSTLLKCISGEMAAQGEIRLFGQPQSQWPAPILARRMAILPQSSALSFSFLAREVVALGRLPHASGKIADEVIIQRCLQAVGAEHLADSAYTVLSGGEKQRIHFARVLAQLDEHMVDSPQTEREPTAAAPKLLMLDEPTSALDLSHQHQTLQTAQRRARQGDAVLVILHDLNLAARYADRILLLNHGQIQADGSPEEVLTAERIKQIFAFDAQVFRHPETGRLHIS
>TCDB__A8GDS6 HemV, component of The heme-specific uptake porter, HemTUV (Serratia proteamaculans (strain 568))
MDNTASLTAQQLRYSLGSRRLINDVSLSINSGEMVAIIGPNGAGKSTLLRLLTGYLAPGCGECQLLGRPLEQWQPQQLAKVRAVMRQHSDLAFPFTVEEVVSMGRAPHGKRDAQRAVQQVMAQTDCLELAQRDYRQLSGGEQQRVQLARVLAQLWQPQPTPAWLFLDEPTSALDLYHQQHTLRLLRTLTRQQPIAVCCVLHDLNLAALYADRILLMHQGQLVATGTPQEVLQAEILTRWYQADLGVVHHPEVALPQVYLRQ
>TCDB__Q32AY3 Hemin import ATP-binding protein hmuV, component of The heme uptake porter, ShuTUV (Burkhard and Wilks, 2008). Transports a single heme per reaction cycle (Mattle et al., 2010). (3-d structure of ShuT is known (2RG7) (Shigella dysenteriae serotype 1 (strain Sd197))
MISAQNLVYSLQGRRLTDNVSLTFPGGEIVAILGPNGAGKSTLLRQLTGYLQPDSGECRLFNKPLNEWSITELAKHRAVMRQNSHMAFPFSVQEVIQMGRHPHRTGNQDNETAQIMALCDCQALANRDYRQLSGGEQQRVQLARLLVQLWEPTPSPKWLFLDEPTSALDIHHQQHLFRLLRQLVHERQFNVCCVLHDLNLAARYADRIVLMQKGKVIANGKPQDVLTQQALTMLYGADITVLEDPANHSPLIVLDH
>TCDB__Q56993 HmuV aka YPO0279 aka Y0539, component of Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Yersinia pestis)
MVDMAVTPVALLEASHLHYHVQQQALINDVSLHIASGEMVAIIGPNGAGKSTLLRLLTGYLSPSHGECHLLGQNLNSWQPKALARTRAVMRQYSELAFPFSVSEVIQMGRAPYGGSQDRQALQQVMAQTDCLALAQRDYRVLSGGEQQRVQLARVLAQLWQPQPTPRWLFLDEPTSALDLYHQQHTLRLLRQLTRQEPLAVCCVLHDLNLAALYADRIMLLAQGKLVACGTPEEVLNAETLTQWYQADLGVSRHPESALPQIYLRQ
>TCDB__Q7W025 Hemin import ATP-binding protein HmuV, component of Heme-iron (hemin) utilization transporter BhuTUV (Bordetella pertussis)
MTLQARNLTLARGGAPILTDVSLTLAPGALVGLLGANGAGKSTLLAALAGELAPRSGQVFLGDADLATLSARQLARRRAVLPQKPSLSFDLGVSDVVGMGAYPFPELDPAAVRQLVRDALEQAGVTHLAQRRYPQLSGGEQQRVQFARVLAQCHAMHAPGQTRYLMLDEPISNLDPRHQMELLATARALAHEAGMGVLVIVHDINQAARWCDTLALLADGRLAALGPPADVLTPDHMRRVYGIEADVLAHPTLPGRLLVLAR
>ecocyc__FEPC-MONOMER ferric enterobactin ABC transporter ATP binding subunit (EC 7.2.2.17) (Escherichia coli K-12 substr. MG1655)
MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTANS
>CharProtDB__CH_088316 ferrichrome transport ATP-binding protein FhuC (Bacillus subtilis)
MNSLSTEQLGIGYGDRVIVEDLNISIPKGKITTLIGPNGCGKSTILKTMSRIMRSHAGAVYLNGKAIHKMSTKDIAKDMAILPQTPEAPSGLTVHELVSYGRFPHQSGFGRLNDEDRRIIKWALEETGMAEYAERPIEALSGGQRQRVWIAMALAQGTELLLLDEPTTYLDLAHQLEILQLLDRLNKEQGRTILMVIHDLNHAARFSHYMIALKKGTVIKEGTALEVMTPDILKQVFQIDAEIVTDPRTNKPVCLTYDLIKNEKELVTV
>ecocyc__FHUC-MONOMER iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) (Escherichia coli K-12 substr. MG1655)
MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY
>TCDB__Q9X665 FhuC aka FhuA, component of Iron (Fe3+)-hydroxamate porter (transports Fe3+-ferrichrome and Fe3+-ferrioxamine B with FhuD1, and these compounds plus aerobactin and coprogen with FhuD2)
MNRLHGQQVKIGYGDNTIINKLDVEIPDGKVTSIIGPNGCGKSTLLKALSRLLAVKEGEVFLDGENIHTQSTKEIAKKIAILPQSPEVADGLTVGELVSYGRFPHQKGFGRLTAEDKKEIDWAMEVTGTDTFRHRSINDLSGGQRQRVWIAMALAQRTDIIFLDEPTTYLDICHQLEILELVQKLNQEQGCTIVMVLHDINQAIRFSDHLIAMKEGDIIATGSTEDVLTQEILEKVFNIDVVLSKDPKTGKPLLVTYDLCRRAYS
>ecocyc__FECE-MONOMER ferric citrate ABC transporter ATP binding subunit (EC 7.2.2.18) (Escherichia coli K-12 substr. MG1655)
MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTLLNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRNPWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVVLLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMAQGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR
>SwissProt__Q81LM1 Petrobactin import ATP-binding protein FpuC; EC 7.2.2.- (Bacillus anthracis)
MISVNKVFYAHSERFQMQNMNVHIKAGEVVSLIGPNGSGKSTLLRLMARLLKQSEGDIVLDGKSIHTMKSADVAKQLAMLPQMHDHQLDLTVKELIEFGRGPHKSWRGRLNKEDEEIVDWALSVTNLEGYEYRLLQSLSGGERQRAWIAMTLAQRTNVLLLDEPTTFLDIVHQLEVMELVKRLNEEFGMTIIMVLHDINQAAQYSDRLLVLKRGKLQYDGVPEEVLCHEMFQHIFGIEVDIFQGSEKPFFTPKRISKKGGAKCEQKNVLPLS
>TCDB__Q9RCF3 ViuC, component of The iron-vibriobactin/enterobactin uptake porter (Vibrio cholerae)
MDTIWDADLQSAALKAEHHRLKTERLSLGYEGKSVCDALDLAIPHGKFSVIVGPNGCGKSTLLKSLCRLLKPLAGQVLLDGQNIHQLPTKVVAKQLGLLPQSALTPEGIKVVDLVSRGRYPHQGLFRQWSRVDERAVEEAMRATHVHELAQHSVDQLSGGQRQRVWVAMGLAQQTPYLLLDEPTTYLDIAHQIELLDLFWRLNRQQGHTLVAVLHDLNQACRYADHLIVLQEGKIVAQGDPHSLVTPALVKQVFGIDCVVMPDPISCTPLIIPYSLKRG
>ENA__CAC34395.1 HmuV protein (Rhizobium leguminosarum)
MIEVSGVSVRLSGKTIISDVAFTAKAGELTAIAGPNGSGKTTTMKAISGELAYGGSVRIGGDEVKGLKPWQLAAIRGVLPQASTISFPFTVREIVRMGLTSGLNLHPDKAEQTAAAALASVDLTGFEGRFYQELSGGEQQRVQLARVLCQIAEPVVDGKPCWLLLDEPVSSLDISHQLTIMTLARNFCERGGGVIAVMHDLNLTALFADRIVLMKSGRLAAPAASFEVLTDETMLSVFGLRVRINQVPADGTPFVLAHSAVSRP
>SwissProt__O32188 Probable siderophore transport system ATP-binding protein YusV (Bacillus subtilis (strain 168))
MGMSAISTETLSLGYGDAVIIDELNLTIPKGEITVFIGSNGCGKSTLLRSLARLMKPRGGSVLLEGRAIAKLPTKEVAKELAILPQGPSAPEGLTVHQLVKQGRYPYQNWLKQWSKEDEEAVERALKATKLEDMADRAVDSLSGGQRQRAWIAMTLAQETDIILLDEPTTYLDMTHQIEILDLLFELNEKEDRTIVMVLHDLNLACRYAHHLVAIKDKRIYAEGRPEEVITCDLVQNVFSMNCQVTQDPLFGTPLCIPHGRGRCIVQEAAFTSHG
>TCDB__Q8GRB0 PvuE, component of The iron-vibrioferrin uptake porter (Vibrio parahaemolyticus)
MLRTQNLSVAYGKQTIIPDLSLSIPQGKITALVGPNGCGKSTLLKTLVRINKPASGQVLYDDKPLSSYGDKRLARSLSFVPQILVSPEGITVRKLVEYGRSPYLSHWGRLSQQDKALVEQAMQDTGVIEFADKPVESLSGGQRQRAWIAMVMAQDTDVVMLDEPTTYLDLSHQVELMKLMRKMNDKGKTVVVVLHDLNQACRYCDHLVVLEKGQLVTQGTPQEVLTEGMLASVFDLQARVFNDPISGTPMCVAV
>SwissProt__Q9HQ18 Cobalamin import ATP-binding protein BtuD; Vitamin B12-transporting ATPase; EC 7.6.2.8 (Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium))
MTLDVTGLDVELAGTRILDDVHASIRDGHLVGVVGPNGAGKSTLLRAMNGLITPTAGTVLVAGDDVHALSSAAASRRIATVPQDASVSFEFTVRQVVEMGRHPHTTRFGTDTDTAVVDRAMARTGVAQFAARDVTSLSGGERQRVLLARALAQAAPVLLLDEPTASLDVNHQIRTLEVVRDLADSEDRAVVAAIHDLDLAARYCDELVVVADGRVHDAGAPRSVLTPDTIRAAFDARVAVGTDPATGAVTVTPLPDRTSAAADTSVHVVGGGDSATPVVRRLVSAGASVSVGPVVEGDTDHETARRVGCPCTSVAPFTRLEDTTAASATRADIAAADVIAVPVAAAARPGVRGLLTGAVPTLAVGDAAGAPEWADRLVACDAVVSAVGALADTPSDGV
>TCDB__Q9A197 Putative ferrichrome ABC transporter aka SiuA aka Spy0386, component of The Fe3+ /Fe3+ferrichrome/Fe3+heme uptake porter; SiuABDG (FTSABCD) (Streptococcus pyogenes serotype M1)
MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSSLLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGRFPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDTIFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKIHYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ
>TCDB__Q47087 CbrD, component of Iron-chrysobactine porter (Erwinia chrysanthemi)
MTAITSRELTLGYASQTIIDNLDIQLPEGKVSVLIGSNGSGKSTLLKSFARLLKPLKGAVILNGEDIHRQSTAAVARELAILPQMPDAPEGITVKQLVSLGRYPYQNWLQQWSEQDEAMVNQALRQTGTDMLAERPVDALSGGQRQRVWIAMTLGQDTEVVLLDEPTTFLDLAHQIEVLDLLRELNRQHGKTIIMVLHDLNLACRYGDHMVAVHNRTAFAQGAPAEILDEALVKTVFNLDCRIVPTRFSTRHCVFRSGARNHRRGRRWHKSAG
>SwissProt__Q81V82 Petrobactin import ATP-binding protein FpuD; EC 7.2.2.- (Bacillus anthracis)
MQKALETKRLTLSYGETIIIDELNLEIPKGEITIFIGSNGCGKSTLLRSLARLLKPTTGDILLDNQAIQSMQTKQIARQMAILPQGPQAPEGLTVLQLVKQGRYPYQTWLKQWSEKDEEMVQNALAATGMTEFAERDVHALSGGQRQRAWIAMTLAQDTDIILLDEPTTYLDMTHQIEVLDLLFELNETEQRTIVMVLHDLNLACRYADNIVAIQDKQIYAQGKPEEVVDEKLVRDVFRMECQISTDPLFGTPLCIPHGKGRRVRKEVAHAMR
>TCDB__Q9RK11 CchE, component of Ferric iron-coelichelin uptake porter, CchCDEF (Streptomyces coelicolor)
MVVQSITGTETEVDGASRLAARGVTVGYGTRSVIDGLDVAIPPGVITTIIGPNGCGKSTLLRTLSRLLRPTGGTVVLDGEDIAALRTRDVAKKLGLLPQAPVAPEGLTVSDLVARGRHPHQSWLRQWSSDDADVVRQALAMTGVSDLADRPVDSLSGGQRQRVWISMTLAQGTDLLLLDEPTTYLDLAHAVDVLDLVDDLHESGRTVVMVLHDLNLAARYSDNLVVMREGAILAQGHPRDVITAGLLHEAFGLRAKVIDDPVGDRPLIVPIGRTHVELDRSAPELLK
>TCDB__Q99YA4 Putative ABC transporter aka SiaC, component of The heme porter, Shp/SiaABC (HtsABC). Shp is a cell surface heme binding protein that transfers the heme directly to HstA (Nygaard et al., 2006). The crystal structure of the heme binding domain of Shp has been solved (Aranda et al., 2007). HtsABC is required for the uptake of staphyloferrin A (Beasley et al. 2009). The Shp cell surface heme receptor feeds iron-heme to the transporter in preparation for uptake (Streptococcus pyogenes serotype M1)
MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGSGKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELVAMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQDTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLKDGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNGIRTQRRDRNKNR