>WP_007668606.1 NCBI__GCF_000319285.1:WP_007668606.1
MVDMTKTTGEKKLTPGDVRAVFIRSNLFQGSWNFERMQALGFCFSMIPAIRRLYPENNEARRQAIKRHLEFFNTHPYVAAPVLGVTLAMEEQRANGAEIDDGAINGLKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFVLFNLVRLATRYYGVAYGYRKGVDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSRITDQNGAEKVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGYAIGLLGQ
>TCDB__P69805 PTND aka MANZ aka PTSM aka GPTB aka B1819, component of The mannose (glucose, 2-deoxyglucose, glucosamine, N-acetylglucosamine, N-acetylmannosamine, mannosamine and fructose) PTS porter/group translocator, ManXYZ (Rephaeli and Saier 1980; Plumbridge 2015). Catalyzes xylose facilitated diffusion in lactobacilli. The order of D-sugar substrate affinities is: glucose > mannose > 2-deoxyglucose > N-acetylglucosamine > glucosamine > N-acetylmannosamine > mannosamine > fructose (Escherichia coli)
MSEMVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCFSMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDGAINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLATRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSRITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGYACGLLGL
>ecocyc__MANZ-MONOMER mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) (Escherichia coli K-12 substr. MG1655)
MVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCFSMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDGAINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLATRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSRITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGYACGLLGL
>biolip__7dyrZ Cryoem structure of mannose transporter manyz and microcin e492 (mcea) complex
EKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCFSMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDGAINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLATRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSRITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGYACGLLGL
>TCDB__Q8Y8W1 Lmo0781 protein, component of Constitutively synthesized sensor, MpoABCD, controlling man operon (see TC# 4.A.6.1.15) expression by interacting with and phosphorylating ManR, the transcriptional regulator of the man operon (Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e))
MSEQITVNEKKITKSDLMGVFIRSNLFQGSWNFERMQSLGFCFSVIPVIKRLYPEKGPEREQAIKRHLEFFNTHPYMAAPILGVTTAMEEQKANGADIDDGAINGIKVGLMGPLAGVGDPIFWGTVRPVLAALGAGFATDGSIIGPILFFVLFNAIRLGFRYWGVFYGYTKGTDVVSDMSGGLLQKLTEGASILGLFVMGALVNKWTTIYVPLVAYTTEDSKTGKDVPTTVQSILDQLMPGLLALLLTFACMWILKKKVNALWLILGLFVVGILGYWSGILGLPPAGYSPLG
>SwissProt__P37083 PTS system sorbose-specific EIID component; EIID-Sor; Sorbose permease IID component (Klebsiella pneumoniae)
MEQKKITQGDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLKADQVAALKRHLVFFNTTPAVCGPVIAVTAAMEEARANGAAIDDGAINGIKVGLMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQLGFRKGVNIVSDMGGNLLQKLTEGASILGLFVMGVLVTKWTTINVPLVVSQTPGADGATVTMTVQNILDQLCPGLLALGLTLLMVRLLNKKVNPVWLIFALFGLGIIGNALGFLS
>TCDB__P26382 PTFD aka LEVG, component of Fructose group translocator, LevDEFG (Bacillus subtilis)
MEKEKRLTKKEIFSMFIRSNFLLGSFNFERVQAMGYCYVMIPAIKKLYGPGAKRNEALQRHLEWFNTHPWLTAPIFGVTAAMEEEMANNKGIDGKAISGMKIGLMGPIAGVGDPIFWGTIRPVLAALGASLALGGNIAGPLLFFFLLNAIRLSTKYYGLKYGYVKGMEILQDLAGNRIQKLTEGASILGLFVMGALVSKWTTINIPIVVSRIKDESGKVDVQTVQNVLDSIMPGALPLGLTLLVAWMLRKGVNPLLIICGIFVIGILGYWAGFLA
>TCDB__D2BKY9 Mannose-specific PTS system, IID component, component of Mannose enzyme II complex, IIAB, IIC, IID. IIC/IID serve allows entry of some bacteriocins including pediocin (class IIa) and lactococcin A (class IIc) (Kjos et al., 2011). Transports and phosphorylates Glucose, Mannose and Glucosamine (Lactococcus lactis subsp. lactis (strain KF147))
MSENKVTLDKKIRRSVMWRSMFLQGSWNYERMQNGGWAYSLIPALKKLYPSGEEAKEALKRHLEFFNTHPYVAAPIIGVTLALEEERANGADIDDAAIQGVKVGMMGPLAGIGDPVFWFTVRPIVGAIAASLATGGSIIAPLFFFIVWNAIRIAFLWYTQEFGYKSGSAITKDLGGGLLQTVTKGASILGMFVLGVLIQRWVTINFNGPNAVVSKIPLQKGAYVEFPKGSVSGTQLHDILGQVGNKLSLDPTKVTYLQDNLNQLIPGLAGLLITLLCMWLLKKKVSPIVIIFGLFVVGILGRWAQIM
>biolip__8hfsZ The structure of lcna, lcia, and the man-pts of lactococcus lactis
KVTLDKKIRRSVMWRSMFLQGSWNYERMQNGGWAYSLIPALKKLYPSGEEAKEALKRHLEFFNTHPYVAAPIIGVTLALEEERANGADIDDAAIQGVKVGMMGPLAGIGDPVFWFTVRPIVGAIAASLATGGSIIAPLFFFIVWNAIRIAFLWYTQEFGYKSGSAITKDLGGGLLQTVTKGASILGMFVLGVLIQRWVTINFNGPNAVVSKIPLQKGAYVEFPKGSVSGTQLHDILGQVGNKLSLDPTKVTYLQDNLNQLIPGLAGLLITLLCMWLLKKKVSPIVIIFGLFVVGILGRWAQIM
>TCDB__Q5M5W8 ManN, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN (Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311))
MAEKIQLSQADRKKVWWRSQFLQGSWNYERMQNLGWAYSLIPAIKKLYTNKEDQAAALKRHLKFFNTHPYVAAPIMGVTLALEEEKANGTEIEDAAIQGVKIGMMGPLAGIGDPVFWFTIRPILGAIGASLAQAGNIAGPLIFFIGWNLIRMAFLWYTQELGYKAGSEITKDMSGGILKDITKGASILGMFILAVLVERWVSVVFTVKLPGKVLPKGAYIEWPKGYVTGDQLKTILGQVNDKLSFDKIQVDTLQKQLDSLIPGLTGLLLTFACMWLLKKKVSPITIIIGLFVVGIVASFFGIM
>biolip__7xnoZ Cryo-em structure of the bacteriocin-receptor-immunity ternary complex from lactobacillus sakei
EQLKLTKKDRISVWLRSTFLQGSWNYERMQNGGWAYTLIPALKKLYKTKEDRSAALVRHMEFFNTHPYVAAPILGVTLALEEERANGAPIDDVTIQGVKVGMMGPLAGIGDPVFWFTVKPIIGALAASLAMSGNILGPIIYFVAWNAIRMAFTWYTQEFGYRAGSKITEDLSGGILQDITKGASILGMFILGSLVNRWVSVKFTPTVSSVKLDKGAFIDWDKLPSGAKGIQSALQQQAQGLSLTDHKITTLQDNLDSLIPGLAALGLTLFCMWLLKKKVSPIVIILGLFVVGIVFHLLHLM
>SwissProt__Q9RGG2 PTS system sorbose-specific EIID component; EIID-Sor; Sorbose permease IID component (Lacticaseibacillus casei (Lactobacillus casei))
MADQPVQVNKLKTKITKGDMFKTFVFENFQQASFNFERIHALAFCVDMIPTIKRVYSKKEDQVAALKRHLVFFNTTPAMCGPIVGVTMALEEGRAAGEPIDDGTINSFKVGLMGPLAGVGDPLMWGTLRPILAALGASLALQGSWLGPILFFVAFNAVRLSLKWYGLQLGFSRGLALVKDMSGNLLQKITEGATVLGLFIMGILVTKWTTINVPLVVSKTTVNGKTTVTTLQNILDQFCPGLLALGWTLLCMYLLRKKVSPILLIFALFGVGIVGYWLGILK
>TCDB__Q2QKM2 ManN aka EIID, component of Glucose porter, ManLMN (Lactobacillus casei)
MAEEVHLTKSDRIKVWWRSTFIQGSWNYERMQNGGWAYTLIPALKRLYHTKEDRSAALKRHLEFFNTHPYLASPIIGVTMALEEERANGAPIDDKAIQGVKVGMMGPLAGVGDPVFWFTVKPIIGALAASLAMAGNIMGPILYFVLWNAIRMAFLWYTQEFGYKAGSKITEDLSGGLLQEVTKGATILGMFILGSLVNRWVSVKFTPVVSDVPNQKGAYIDWSSLPSGSKGIQKALELQSQGLSLTKNKVLTLQDNLDSLIPGLMGLLLTLFCMWLLKKKVSPIVIILGLFVVGVVFHVVGLM
>TCDB__E1UCI2 PTS system, mannose/fructose/sorbose family, IID component, component of The primary glucose /mannose uptake transporter, ManLMN (Listeria monocytogenes serotype 4a (strain L99))
MAEKIELSKRDRLRVAWRSTFIQGSWNYERMQNGGWAFSMIPAIKKLYKTKEDRSSALKRHLEFFNTHPYIASPILGVTLALEEERANGAEVDDVAIQGVKVGMMGPLAGVGDPVFWFTIRPMLGALGASLALSGNILGPILFFVAWNVIRWGFMWYTQEFGYKAGSKITDDLSGGLLQDITKGASILGMFVLAALVQRWVNIQFAPIISKVKLDEGAYIDWSHLPQGAQGIKTALEQQQAGLALSEIKVTTLQNNLDNLIPGLAAVALTFLCMWLLKKKISPIIIILGLFVVGIVGHLIGLL
>biolip__7vlxZ Cryo-em structures of listeria monocytogenes man-pts
ELSKRDRLRVAWRSTFIQGSWNYERMQNGGWAFSMIPAIKKLYKTKEDRSSALKRHLEFFNTHPYIASPILGVTLALEEERANGAEVDDVAIQGVKVGMMGPLAGVGDPVFWFTIRPMLGALGASLALSGNILGPILFFVAWNVIRWGFMWYTQEFGYKAGSKITDDLSGGLLQDITKGASILGMFVLAALVQRWVNIQFAPIISKVKLDEGAYIDWSHLPQGAQGIKTALQQQQAGLALSEIKVTTLQNNLDNLIPGLAAVALTFLCMWLLKKKISPIIIILGLFVVGIVGHLIGLL
>BRENDA__Q5IRC0 protein-Npi-phosphohistidine-D-mannose phosphotransferase (EC 2.7.1.191) (Streptococcus suis)
MSEKIQLSVSDRKKVWWRSTFLQGSWNYERMQNLGWAYAMIPAIKKLYTKKEDQAAALERHLEFFNTHPYVASPILGVTLALEEERANGAEIDDTAIQGVKIGMMGPLAGIGDPVFWFTVRPILGALGASLALSGNIMGPIIFFLGWNIIRMAFLWYTQEFGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSITFAVDLPAKQLSEGAYIVFPEGTVTGAELKGILGQALSGLSLEPTQAQTLQGQLDSLIPGLMGLLLTFLCMHLLKKKVTPITMIIGLFIVGILARFFGIM
>TCDB__Q04GJ9 PTS system IID component, Man family, component of The hexose (glucose and fructose demonstrated) PTS uptake system (Oenococcus oeni (strain BAA-331 / PSU-1))
MAKDKITLTKGDRLHVAWRSTFIQGSWNYERMQNGGWVYALIPALNKLYKTKEDRAAAYKRHLVFFNTHPYLASPIIGVTLALEEDRANGAPVDDVAIQGVKVGMMGPLAGVGDPVFWYTVRPLLGALGATLALSGNVLGPILFWVLWNIIRWAFMWYTQEFGYRAGSRITDDLSGGLLKTVTRGASMMGMFVLAALIERWVSIKFTPVVSKVTLSKGAYIDWGKLPSGTKGIREALTEQANGLSLTKIQTTTLQQNLDSLIPGLMALLLTFACMWLLKKKVSPIIIILGIFVIGVGGHLLGLL
>metacyc__STM14_RS23780-MONOMER fructoselysine/glucoselysine PTS enzyme IID component (Salmonella typhimurium (strain 14028s / SGSC 2262))
MISDKDRQQAETTGLVTARDLRRVFWRSFQMEFSWNYERQMNLAFVYTLIPVLKKLYSRKEDLAEALKRHLAFFNTTPHIVTLILGITVAMEEKNSQQKEMDASSIDNVKASLMGPLAGIGDSFFWGTLRLIATGIGTSLALKGNILGPILFLLVFNVPHILARWFFTRWGYVLGTGVLQRIQQSGMMESLTYGASIIGLMVVGAMTASMIDITIPITFGTGEAKTHVQDIINDIMPCLLPLISFAIVYWLLGKKVKPLTIIGGIALVGIFGSWIGLF
>TCDB__Q97N94 PTS system, IID component, component of The fucose PTS uptake transporter, IIA/IIB/IIC/IIDFuc (FcsABCD) (Manzoor et al. 2015). Expression in response to fucose is under the control of the FcsR transcriptional activator, and its DNA binding site has been identified (Streptococcus pneumoniae)
MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLKKLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMGPLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYTKGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEMITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK
>metacyc__MONOMER-18129 D-glucosaminate PTS permease components EIID (EC 2.7.1.203) (Salmonella typhimurium (strain 14028s / SGSC 2262))
MSSDVMQHELVERARESGALTKADITKAWFIYWLGAEVSSSYERLQSLIFCASMTPIIKKLYPQKEEQVEALKRHLNFFNSEQTFGAVIQGISIAMEEQKTRGEPINDSSITGIKTGLMGPLAGMGDSIIWAAVMPLLIAIFIPFAANGSAMGGIIPLILYPAITLAISYGMVHKGYTLGRDSIIGLLQGGRIKELIYGANVLGLIMMGALSASYVKITTPLKISALKGSEVVVQQILDSIAPGLLPLAAVFAIYFYLVKKGPRYTTILLSIVALSIVCSLLGVL
>TCDB__CAQ67971.1 CAQ67971.1 Putative phosphotransferase system enzyme II, component of D-ribitol (D-aldonitol) (a pentitol) PTS Enzyme II complex RtlABCD (Lactobacillus casei BL23)
MSEEDKKEQLEEKELPSEQKPNAKKLSKRDVVKAFWRWTFFSHANYNYERLQATGVIHALSPIFKKLYGDDEDEMKAALLRHMQFFNTEPHFGGSILGVTIAMEEQKANGAPITDETINGLKTGLMGPLAGIGDTLWQGTLIPILLSFTISFAAKGNILMGPVLFAVLHLGIIWSIGYLAWMQGYNLGKEGIAKILQGSLLPTVMTYAQTLGPIVIGALSATFVKISTPMKLHLGKTVMKVQTGILDKLVLGLLPLAVTLLTYYLLRKKFKPTTVLLILVGIGVVGGIFWII
>ecocyc__AGAD-MONOMER galactosamine-specific PTS enzyme IID component (Escherichia coli K-12 substr. MG1655)
MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKKIYKDDKPGLSAAMKDNLEFINTHPNLVGFLMGLLISMEEKGENRDTIKGLKVALFGPIAGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGVKAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDNTHSVALQQDFFDKVFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL
>TCDB__B3WB11 PTS system, IID component, component of Fucosyl-α-1,3-N-acetylglucosamine PTS uptake porter, AlfEFG (next to an operon encoding a fucosidase (AlfB) and a transcriptional regulator of the GntR family, AlfR) (Lactobacillus casei (strain BL23))
MTIRIQTKEAMKMPSANTKTDLPVKLTKHDLFQANWRWLWGSQICWNYERMMSTGYLFTMLPTLKKLYKNDQDLIEMMKMHNQFFNTNAYVGGFIVGMDMAIEEKQGRKAEDTVAGLKAGLMGPFAGVGDTIVGVILPTIFGSIGAYMGLKGNPTGAILWLLVNFAVLILRFFLLPLGYSQGEKLIYATGDKLNRITDAAILLGVTVVGALIPTVISANVPLVFKTGKVVLKAQTVLDQIMPSLVPVALVALCYWLLGKKRMNSTRLIVLVLILGIALGAFGIIGK
>TCDB__Q9KIQ2 AgaE, component of N-acetyl galactosamine (GalNAc or Aga) porter (used the same IIA protein (AgaF) as does 4.A.6.1.5) (Escherichia coli)
MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRVAWRSMLLQASFNYERMQASGWLYGLLPALKKINTNKRDLARAMKGHMGFFNTNPFLVTFVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLRYCRLCGGIEPVLALQGSILGAVVFIVLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGALVATYVRLSTTLEITAGDAVVKLQADVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLIAVTVVLGIVGKFCHFL