>CA265_RS08355 FitnessBrowser__Pedo557:CA265_RS08355
MFSLKNKKAVVTGGGSGIGKAIATILAKQGAEVHIIELGTEHAQDTLDEIKTNGGVAFSYGCDVSDHQAVAAVFNEIGNINILINNAGIAHIGKADTTDEADFDRVMRVNVKGVYNCLHAAIPQIRLSGGGVIINMASIAALIGLPDRFVYSAAKGAVKAITMSVAKDYIGENIRCNSISPARVHTPFVDGFLQKNYPDNIPEMFEKLSKTQPIGRMAKPEEVGALALYLCSDEASFITGCDYPIDGGFTTLNN
>biolip__6ixmC Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD
GILDNKVALVTGAGSGIGLAVAHSYAKEGAKVIVSDINEDHGNKAVEDIKAQGGEASFVKADTSNPEEVEALVKRTVEIYGRLDIACNNAGIGGEQALAGDYGLDSWRKVLSINLDGVFYGCKYELEQMEKNGGGVIVNMASIHGIVAAPLSSAYTSAKHAVVGLTKNIGAEYGQKNIRCNAVGPAYIETPLLESLTKEMKEALISKHPMGRLGKPEEVAELVLFLSSEKSSFMTGGYYLVDGGYTAV
>reanno__BFirm_BPHYT_RS34215 2-keto-3-deoxy-L-fuconate 4-dehydrogenase FucDH (Burkholderia phytofirmans PsJN)
MTQRLAGKTALITAAGQGIGLATAELFAREGARVIATDIRIDGLAGKPVEARKLDVRDDAAIKALAAEIGAVDVLFNCAGFVHAGNILECSEEDWDFAFDLNVKAMYRMIRAFLPAMLDKGGGSIINMSSAASSVKGVPNRFAYSASKAAVIGLTKSVAADFITRGVRCNAICPGTVASPSLEQRIVAQAQAQGATLDAVQAAFVARQPMGRIGKPEEIAALALYLGSDESSFTTGHAHVIDGGWSN
>metacyc__MONOMER-3121 cyclohexanol dehydrogenase (EC 1.1.1.245) (Acinetobacter sp. (strain SE19))
MEKIMSNKFNNKVALITGAGSGIGKSTALLLAQQGVSVVVSDINLEAAQKVVDEIVALGGKAAANKANTAEPEDMKAAVEFAVSTFGALHLAFNNAGILGEVNSTEELSIEGWRRVIDVNLNAVFYSMHYEVPAILAAGGGAIVNTASIAGLIGIQNISGYVAAKHGVTGLTKAAALEYADKGIRINSVHPGYIKTPLIAEFEEAEMVKLHPIGRLGQPEEVAQVVAFLLSDDASFVTGSQYVVDGAYTSK
>BRENDA__A0A2D0WG37 cyclohexanol dehydrogenase (EC 1.1.1.245) (Acidovorax sp.)
MKRVENKVILVTGGAMGMGRSHSELLAAQGAWVFVADVNATEGQATVDSIRKNGGKADFLELDVTQEAQWNAALAQITERAGRLDVLVNNAGILILKPMQDTTNEEWDRVFDVNVRGLFIGTRAAVPLMQKAGGGTIVNVSSIYGLVGAPGASAYEASKGAVRLFTKSCAVDLAPFNIRVNSVHPGVIETQMTKAMLDDPIIRPALLGPTLLKRPAQPIEVSQAVLFLASDESSFVHGAELVVDGGYTAN
>BRENDA__A0A088MI02 tropinone reductase I (EC 1.1.1.206) (Brugmansia arborea)
MEESKVSMNDKNEERWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELQECLDFWRKNGLNVEGSVCDLLSRTEREKLMQTVAHIFDEKLNILVNNAGVVIHKEAKDFTEEDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAASYITGQIIWADGGFTANGGF
>metacyc__TSACCOTE-MONOMER 4-sulfobenzyl alcohol dehydrogenase subunit (EC 1.1.1.257) (Comamonas testosteroni)
MNLNKQVAIVTGGASGFGAAIARRLSQAGAAVLVADLNAEGAQRMATELNAAGGRALGMACDVSKEADYRAVVDAAIAQLGGLHIVVNNAGTTHRNKPALAVTEDEFDRVYRVNLKSVYWSAQCALPHFAQQGHGVMVNVASTTGVRPGPGLTWYSGSKAAMINLTKGLALEFARSGVRINAVNPMIGETPMMADFMGMEDTPANRERFLSRIPLGRFTRPDDVASAVAFLASDDASFLTGVCLDVDGGRNI
>reanno__HerbieS_HSERO_RS19365 2-keto-3-deoxy-L-fuconate 4-dehydrogenase FucDH (Herbaspirillum seropedicae SmR1)
MSASTGRLAGKTVLITAAAQGIGRASTELFAREGARVIATDISKPHLDELAGIAGVETHLLDVTDDAAIKALVAKIGTIDVLFNCAGYVAAGNILECDDKAWDFSFNLNAKAMFHTIRAVLPGMLAKKAGSIVNIASAASSVKGVANRFAYGASKAAVVGLTKSVAADFVAQGIRCNAICPGTIESPSLNQRISTQAKETGKSEEEVRAAFVGRQPMGRIGKAEEVAALALYLASDESNFTTGSIHMIDGGWSN
>metacyc__MONOMER-13848 tropinone reductase (EC 1.1.1.206) (Datura stramonium)
MEESKVSMMNCNNEGRWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAASYITGQIIWADGGFTANGGF
>metacyc__MONOMER-21866 2-dehydro-3-deoxy-D-pentonate/2-dehydro-3-deoxy-L-fuconate 4-dehydrogenase (EC 1.1.1.434) (Herbaspirillum huttiense)
MSASTGRLAGKTVLITAAAQGIGRASTELFAREGARVIATDISKTHLEELASIAGVETHLLDVTDDDAIKALVAKVGTVDVLFNCAGYVAAGNILECDDKAWDFSFNLNAKAMFHTIRAVLPGMLAKKAGSIVNIASAASSVKGVANRFAYGASKAAVVGLTKSVAADFVSQGIRCNAICPGTIESPSLNQRISTQAKETGKSEDEVRAAFVARQPMGRIGKAEEVAALALYLASDESNFTTGSIHMIDGGWSN
>biolip__1ae1B Tropinone reductase-i complex with NADP
RWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAASYITGQIIWADGGFTANGGF
>BRENDA__Q9AR59 tropinone reductase I (EC 1.1.1.206) (Solanum tuberosum)
MAELREKWSLKGTTALVTGGSKGIGYAIVEELANFGARVYTCSRNENELQECLDIWRKKGLKVEGSVCDLLSRTEREKLMKTVEDVFDGKLNILVNNAGVAIHKEAKDFTKEDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFVSSIAGFSALPSLSLYSASKGAINQMTKNLACEWAKDNIRVNSVAPAVILTPLVETAIKKNPQQKEEIDSFVVKTPLGRAGKPEEASAVIAFLCFPAASYITGQIIWADGGFTANGGF
>SwissProt__Q8JZV9 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 (Mus musculus (Mouse))
MGRLDGKVIVLTAAAQGIGRASALAFAREGAKVIATDINESKLQELESYRGIQTRVLDVTKKRQIDQFASEIERIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMFLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARDNPKEALKTFLNRQKTGRFASAEEVALLCVYLASDESAYVTGNPVIIDGGWSL
>SwissProt__D4A1J4 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 (Rattus norvegicus (Rat))
MGRLEGKVIVLTAAAQGIGRASALAFAREGAKVIATDINEAKLQELENYPGIQTRVLDVTKKRQIDQFASEIEKIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARDDPKEALKAFLNRQKTGRFASAEEVALLCVYLASDESAYVTGTPVVIDGGWSL
>biolip__7djsD Crystal structure of isopiperitenol dehydrogenase from pseudomonas aeruginosa complexed with NAD
KLLSGQVALVTGGAAGIGRATAQAFAAAGVKVVVADLDSAGGEGTVEAIRQAGGEAVFIRCDVTRDAEVKALVEGCAAAYGRLDYAFNNAGIEIEQGKLADGNEAEFDAIMAVNVKGVWLCMKHQIPLMLAQGGGAIVNTASVAGLGAAPKMSIYAASKHAVIGLTKSAAIEYAKKGIRVNAVCPAVIDTDMFRRAYEADPRKAEFAAAMHPLGRVGRVEEIAAAVLYLCSDNAGFTTGIALPVDGGATAI
>metacyc__MONOMER-7722 cyclopentanol dehydrogenase (EC 1.1.1.163) (Comamonas sp. (strain NCIMB 9872))
MGRVNDKVVLVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVIEPMRKAHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPGVIATPMTQQILDAPQSARALLGPTLLGRAAQPMEVSQAVLFLVSDEASFVHGSELVVDGGYTAN
>metacyc__MONOMER-14370 cyclohexanol dehydrogenase (Aromatoleum aromaticum (strain EbN1))
MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR
>SwissProt__Q561X9 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 (Danio rerio (Zebrafish) (Brachydanio rerio))
MGRLDGKVIVLSAAAQGIGKASAIAFAKEGAQVTATDINGEKLKELDGIPGIKTKVVDVTKKDQVDALAKDFDHVDVLFNIAGFVHHGSILDCEESDWDFTMNVNVRSMYLMIKAFLPKMLARKSGNIINMASVASSIKGVVNRCVYSTSKAAVIGLTKSVAADFLEQGIRCNCICPGTVDTPSLRERIQARPDPEQAFKDFMARQRTGRLCTAEEVAHLCVYLASDESTFVTGTEVIIDGGWRL
>BRENDA__U5PUZ1 tropinone reductase I (EC 1.1.1.206) (Withania somnifera)
MDESSVCMNGNHGRSRWSLKGTTALVTGGSKGIGYAIVEELAGLGATVYTCSRNENELQQCLEIWREKGLKVEGSICDLLVRTEREKLMQTVADVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKNLACEWAKDNIRVNSVAPGVIVTPLVEAAIKKNPQQKDEIDNFVVKTPMGRAGKPEEVAAVIAFLCFPAASYVTGQIIWADGGFTANGGF
>PDB_4urf_B Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1
MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAF
GRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKH
GVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYA
VDGGYLAR
>PDB_4urf_A Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1
MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAF
GRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKH
GVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYA
VDGGYLAR
>BRENDA__R4QQK2 tropinone reductase I (EC 1.1.1.206) (Anisodus luridus)
MGESKVYMNGNHGGTRWSLKGTTALVTGGSKGIGYAVVEELAGFGATVYTCSRNEKELQQCLEIWSKEGLKVEGSVCDLLLRSEREKLMQAVGDLFNGKLNILVNNAGVVIHKEAKDFTEEDYNIVMGTNFEAAYHLSQLAYPLLKASENGNVIFLSSIAGFSALPSVSLYSASKAAINQMTKNLACEWAKENIRVNSVAPGIILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPKEVSALIAFLCFPAASYITGQIIWADGGFTANGGF
>BRENDA__B2L2W8 tropinone reductase I (EC 1.1.1.206) (Anisodus acutangulus)
MGESKVYMNGNHGGTRWSLKGTTALVTGGSKGIGYAVVEELAGFGATVYTCSRNEKELQQCLEIWSKEGLKVEGSVCDLLLRSEREKLMQAVGDLFNGKLNILVNNAGVVIHKEAKDFTEEDYNIVMGTNFEAAYHLSQLAYPLLKASENGNVIFLSSIAGFSALPSVSLYSASKAAINQMTKNLACEWAKENIRVNSVAPGIILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPKEVSALISFLCFPAASYITGQIIWADGGFTANGGF
>metacyc__MONOMER-13285 2-(R)-hydroxypropyl-CoM dehydrogenase subunit (EC 1.1.1.268) (Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2))
MSRVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVNGAALVMDGAYTAI
>metacyc__MONOMER-18270 <i>meso</i>-butanediol dehydrogenase [(R)-acetoin-forming] (EC 1.1.1.304; EC 1.1.1.76) (Serratia marcescens)
MRFDNKVVVITGAGNGMGEAAARRFSAEGAIVVLADWAKEAVDKVAASLPKGRAMAVHIDVSDHVAVEKMMNEVAEKLGRIDVLLNNAGVHVAGSVLETSIDDWRRIAGVDIDGVVFCSKFALPHLLKTKGCIVNTASVSGLGGDWGAAYYCAAKGAVVNLTRAMALDHGGDGVRINSVCPSLVKTNMTNGWPQEIRDKFNERIALGRAAEPEEVAAVMAFLASDDASFINGANIPVDGGATASDGQPKIV
>biolip__6vspB Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a
FQGRFDNKVVVITGAGNGMGEAAARRFSAEGAIVVLADWAKEAVDKVAASLPKGRAMAVHIDVSDHVAVEKMMNEVAEKLGRIDVLLNNAGVHVAGSVLETSIDDWRRIAGVDIDGVVFCSKFALPHLLKTKGCIVNTASVSGLGGDWGAAYYCAAKGAVVNLTRAMALDHGGDGVRINSVCPSLVKTNMTNGWPQEIRDKFNERIALGRAAEPEEVAAVMAFLASDDASFINGANIPVDGGATASDGAPKI
>BRENDA__L7QI79 tropinone reductase I (EC 1.1.1.206) (Withania coagulans)
MDESSVCMNGNHGRSRWSLKGTTALVTGGSKGIGYATVEELAGLGATVYTCSRNENELQQCLEIWREKGFKVEGSICDLLVRTEHEKLMQTVADVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKNLACEWAKDNIRVNSVAPGVIVTPLVEAAIKKNPQQKDEIDNFVVKTPMGRAGKPGEVAAVIAFLCFPAASYVTGQIIWADGGFTANGGF
>PDB_6xew_A Structure of serratia marcescens 2,3-butanediol dehydrogenase
GRFDNKVVVITGAGNGMGEAAARRFSAEGAIVVLADWAKEAVDKVAASLPKGRAMAVHIDVSDHVAVEKMMNEVAEKLGR
IDVLLNNAGVHVAGSVLETSIDDWRRIAGVDIDGVVFCSKFALPHLLKTKGCIVNTASVSGLGGDWGAAYYCAAKGAVVN
LTRAMALDHGGDGVRINSVCPSLVKTNMTNGWPQEIRDKFNERIALGRAAEPEEVAAVMAFLASDDASFINGANIPVDGG
ATASDGQPKIV
>PDB_6vsp_A Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a
GRFDNKVVVITGAGNGMGEAAARRFSAEGAIVVLADWAKEAVDKVAASLPKGRAMAVHIDVSDHVAVEKMMNEVAEKLGR
IDVLLNNAGVHVAGSVLETSIDDWRRIAGVDIDGVVFCSKFALPHLLKTKGCIVNTASVSGLGGDWGAAYYCAAKGAVVN
LTRAMALDHGGDGVRINSVCPSLVKTNMTNGWPQEIRDKFNERIALGRAAEPEEVAAVMAFLASDDASFINGANIPVDGG
ATASDGAPKIV
>ecocyc__EG12133-MONOMER oxidoreductase UcpA (EC 1.1.1.304) (Escherichia coli K-12 substr. MG1655)
MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEKLADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMSDDDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKAAIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAIPMRRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPETVSVGI
>SwissProt__D4Z260 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX; 2,5-DDOL dehydrogenase; EC 1.1.1.- (Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum))
MANRLAGKVALITGGASGLGAAQAKRFAEEGAKVVIGDLNEEMAKGVVAEIRAAGGDALFIRLDVTDAASWNNAIAAAVEAFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTAIFLGIKAAIPELVKSGNGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAALEFVDRGVRVNTIVPGGMNTPITANVPPDVLKQQTSQIPMGKLGDPIDIANGALFLASDEAKYITGVDLPIDGGWSVGV
>BRENDA__A0A6B7HCZ2 tropinone reductase I (EC 1.1.1.206) (Przewalskia tangutica)
MGEPKVYMNDNRGGIRWSLKGTTALVTGGSKGIGYAVVEELAGLGATVYTCSRNEKELQQCLDIWSKEGLKVEGSVCDLLLRSEREKLMQTVGDLFNGKLNILVNNAGVVIHKEAKDFTEEDYKIIMGTNFEAPYHLSQLVYPLLKASENGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKNLACEWAKDNIRVNSVAPGVILTPLIETAIKKNPHQKEEIDNFIVKTPMGRAGKPKEVSSLIAFLCFPAASYITGQIISADGGFTANGGF
>SwissProt__A7IQH5 2-(S)-hydroxypropyl-CoM dehydrogenase 3; S-HPCDH 3; 2-[(S)-2-hydroxypropylthio]ethanesulfonate dehydrogenase 3; Aliphatic epoxide carboxylation component IV; Epoxide carboxylase component IV; SHPCDH3; EC 1.1.1.269 (Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2))
MSNRLKNEVIAITGGGAGIGLAIASAALREGAKVALIDLDQGLAERSAAMLSTGGAVAKGFGADVTKAADITAAITSAEQTIGSLTGLVNNAGIAGFGSVHDADAAAWDRIMAVNVTGTFLASKAALAGMLERHKGTIVNFGSVAGLVGIPTMAAYCAAKGAIVNLTRQMAADYSGRGVRVNAVCPGTVTSTGMGQQLLGSDTSPEVQARRLAKYPIGRFGTPEDIAEAVIFLLSDQAAFVTGAAFAVDGGMTAI
>biolip__4ituA Crystal structure of s-2-hydroxypropyl coenzyme m dehydrogenase (s- hpcdh) bound to s-hpc and nadh
NRLKNEVIAITGGGAGIGLAIASAALREGAKVALIDLDQGLAERSAAMLSTGGAVAKGFGADVTKAADITAAITSAEQTIGSLTGLVNNAGIAGFGSVHDADAAAWDRIMAVNVTGTFLASKAALAGMLERHKGTIVNFGSVAGLVGIPTMAAYCAAKGAIVNLTRQMAADYSGRGVRVNAVCPGTVTSTGMGQQLLGSDTSPEVQARRLAKYPIGRFGTPEDIAEAVIFLLSDQAAFVTGAAFAVDGGMTAI
>biolip__7v1qA Leifsonia alcohol dehydrogenases lnadh
MAQYDVADRSAIVTGGGSGIGRAVALTLAASGAAVLVTDLNEEHAQAVVAEIEAAGGKAAALAGDVTDPAFGEASVAAANALAPLKIAVNNAGIGGEAATVGDYSLDSWRKVIEVNLNAVFYGMQPQLKAMAANGGGAIVNMASILGSVGFANSSAYVTAKHALLGLTQNAALEYAADKVRVVAVGPGFIRTPLVEANLSAEALAFLEGKHALGRLGEPEEVASLVAFLASDAASFITGSYHLVDGGYTAQ
>BRENDA__Q9AE70 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) (Pseudomonas putida)
MTLKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGSQVRGAAWNVDGGWLAQ
>biolip__2q2qD Structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
TLKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGSQVRGAAWNVDGGWLAQ
>metacyc__BSU15910-MONOMER 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (Bacillus subtilis (strain 168))
MLNDKTAIVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIAVKADVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMKEDEWDDVININLKGVFNCTKAVTRQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASRNITVNAIAPGFISTDMTDKLAKDVQDEMLKQIPLARFGEPSDVSSVVTFLASEGARYMTGQTLHIDGGMVM
>SwissProt__Q92EU6 NAD-dependent glycerol dehydrogenase; Dha-forming NAD-dependent glycerol dehydrogenase; EC 1.1.1.6 (Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262))
MTFKGFDKDFNITDKVAVVTGAASGIGKAMAELFSEKGAYVVLLDIKEDVKDVAAQINPSRTLALQVDITKKENIEKVVAEIKKVYPKIDILANSAGVALLEKAEDLPEEYWDKTMELNLKGSFLMAQIIGREMIATGGGKIVNMASQASVIALDKHVAYCASKAAIVSMTQVLAMEWAPYNINVNAISPTVILTELGKKAWAGQVGEDMKKLIPAGRFGYPEEVAACALFLVSDAASLITGENLIIDGGYTIK
>BRENDA__Q1J2J0 L-iditol 2-dehydrogenase (EC 1.1.1.14) (Deinococcus geothermalis)
MTSTAQMPHILDLFRLDGRHALVTGGAQGIGFEIARGLAQAGARVTIADLNPDVGEGAARELDGTFERLNVTDADAVADLARRLPDVDVLVNNAGIVRNAPAEDTPDDDWRAVLSVNLDGVFWCCREFGRTMLARGRGAIVSTASMSGLISNHPQPQAAYNASKAAVIHLTRSLAGEWASRGVRVNAVAPGYTATPLTRRGLETPEWRETWLKETPLGRLAEPREIAPAVLYLASDAASFVTGHTLVVDGGYTVW
>BRENDA__Q5KST5 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) (Pseudomonas fragi)
MLKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDGADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFHGTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLASDAAAQITGTTVSVDGGWTAR
>BRENDA__A0A1Z3FWF0 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) (Rhodococcus sp. P14)
MNTEFSGKTVAVTGAGSGMGRAEAQLLASLGAHVWVADIDSTAGEAVIDQIRDKGGAADFHRLDVTDPDAWSRFAEVIDAADGNLDGLVNNAGVSFRYGIEDTSVEDWRRVMAINLDSVFYGMRACAPLLKCNGGGSIVNISSIAGMLGYFAAAYGASKWGVRGLSKVGALEFAEHHVRVNSVHPGLVETPLLTSGTTEFVDESLKSVPAGRSADPDEVAETVAFLLSDRSTYITGTEIVIDGGLTSGGLYHRITRELG
>metacyc__MONOMER-21811 2-dehydro-3-deoxy-L-fuconate 4-dehydrogenase (EC 1.1.1.434) (Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25))
MAADRTAAGTAVRRRQCRGGVRRQRTHVLSSATAGGPHPRNLIGMTVSIPTTPNTRLQGKRCLITAAGAGIGRESALACARAGAHVIATDIDAAALQALAAESDAITTQLLDVTDAAAITALVAAHGPFDVLFNCAGYVHQGSILDCDEPAWRRSFSINVDAMYYTCKAVLPGMLERGRGSIINMSSVASSIKGVPNRFVYGVTKAAVIGLSKAIAADYVAQGVRCNAICPGTIKTPSLGQRVQALGGDEQAVWKSFTDRQPMGRLGDPREIAQLVVYLASDESSFTTGQTHIIDGGWSN
>PDB_4gh5_A Crystal structure of s-2-hydroxypropyl coenzyme m dehydrogenase (s- hpcdh)
NRLKNEVIAITGGGAGIGLAIASAALREGAKVALIDLDQGLAERSAAMLSTGGAVAKGFGADVTKAADITAAITSAEQTI
GSLTGLVNNAGIAGFGSVHDADAAAWDRIMAVNVTGTFLASKAALAGMLERHKGTIVNFGSVAGLVGIPTMAAYCAAKGA
IVNLTRQMAADYSGRGVRVNAVCPGTVTSTGMGQQLLPEVQARRLAKYPIGRFGTPEDIAEAVIFLLSDQAAFVTGAAFA
VDGGMTAI
>PDB_2ztl_A Closed conformation of d-3-hydroxybutyrate dehydrogenase complexed with NAD+ and l-3-hydroxybutyrate
MLKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDGADLSKGEAVRGLVDNAVRQ
MGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFHGTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKH
GVVGFTKVTALETAGQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLAS
DAAAQITGTTVSVDGGWTAR
>BRENDA__A0A545BBR2 (1R,2S)-ephedrine 1-dehydrogenase (EC 1.1.1.423) (Arthrobacter sp. TS-15)
MNGRIMLVEGKNGIVTGAAGGIGRASAVAFAREGANVVIGDLQARLEDLEETARQVKKAGGEARVLVMDVTALADQEHAVRTVIENFGTLDFAHNNAGIELQKTALETTEEEWDRVHDVNLKGVFLGMKAQLRAMIDNGGGSIVNTASAAGILGLPGYSGYASSKHGVVGLTKSVAVEAADTGVRINAVCPASIATPMLLSLPAEEQETLLSWQAIKRLGKPDEVAQAVVWLASDRASFITGVSLPVDAGYSAF
>BRENDA__C0IR58 aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) (Ralstonia sp.)
MYRLLNKTAVITGGNSGIGLATAKRFVAEGAYVFIVGRRRKELEQAAAEIGRNVTAVKADVTKLEDLDRLYAIVREQRGSIDVLFANSGAIEQKTLEEITPEHYDRTFDVNVRGLIFTVQKALPLLRDGGSVILTSSVAGVLGLQAHDTYSAAKAAVRSLARTWTTELKGRSIRVNAVSPGAIDTPIIENQVSTQEEADELRAKFAAATPLGRVGRPEELAAAVLFLASDDSSYVAGIELFVDGGLTQV
>BRENDA__A0A0M4UR95 L-xylulose reductase (EC 1.1.1.10) (Rhizomucor pusillus)
MSAPLPTLPEFSLKDKVAVVTGGGRGLGLEMSRALAESGANVAIMFVSSEKTHDTAAQIAKDFNVTCKAYKADIVDPVAVKEAVDQIYKDFGAIDVFVANAGVSIGGKTEEYDLNDWKKTMDINVNGVFYSIQAASKYMLEKGKGSVIITSSISGHVANRPQPQCAYNTSKGATTLMTKALATEWATKGIRVNAICPGYMRTELLDITLKNNPEWERQWNQFTPMGRVGEAKELRGAVVFLASDASTYVTGIELFVDGGYTCV
>biolip__5yssB Crystal structure of aminocaproic acid cyclase in complex with NAD (+)
NLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGADLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTTRLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSDGAAQVRGVAWNMDGGWVAQ
>SwissProt__A0A1C9II22 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- (Narcissus aff. pseudonarcissus MK-2014 (Daffodil))
MSLEKRWSLEGTTALVTGGTKGIGHAIVEELVGFGARVYTCSRNEAELRKCLQEWENLKYDVTGSVCDVSSRTEREKLAEEVSSVFNGKLNILINNAGGYVNKPIDGFTAEDFSFLVAVNLESAFHLCQLAHPMLKASGTGSIVHISSCCAQIAIPGHSIYSSTKGAINQLTRNLACEWAKDNIRTNSIAPGAIRTPGTESFVIDKDALDREVSRVPFGRIGEPEEVASLAAFLCMPSASYITGQVICVDGGRTING
>BRENDA__A0A545BBS8 pseudoephedrine dehydrogenase (EC 1.1.1.422) (Arthrobacter sp. TS-15)
MINMRNRVAIVTGGAMGMGNGCARKLAEAGAKVYLIDRSNLVAAAAQDMREAGLNANHVQVDITDQESLTSAYDGIAAESGRLDVLVNAAGVGDSRMFLDVDDAHYKKVIDVNVRGTWNSCRAAVPHMLSNKHGRIINFGSISGPIVADPGWTVYALSKGAIFGFTKALASEFAGQNILVNAILPGSMDTPMMRAAAADTNPADPQSVIDEIAAAVPLKRLGTIDDAGNLALFLASDLASYLTGQAIVLDGAFTLAEYQSGGLEAPAETPALVN
>PDB_5fff_A Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and piperonal
MSLEKRWSLEGTTALVTGGTKGIGHAIVEELVGFGARVYTCSRNEAELRKCLQEWENLKYDVTGSVCDVSSRTEREKLAE
EVSSVFNGKLNILINNAGGYVNKPIDGFTAEDFSFLVAVNLESAFHLCQLAHPMLKASGTGSIVHISSCCAQIAIPGHSI
YSSTKGAINQLTRNLACEWAKDNIRTNSIAPGAIRTPGTESFVIDKDALDREVSRVPFGRIGEPEEVASLAAFLCMPSAS
YITGQVICVDGGRTING
>biolip__6qheA Alcohol dehydrogenase from arthrobacter sp. Ts-15 in complex with NAD+
HMINMRNRVAIVTGGAMGMGNGCARKLAEAGAKVYLIDRSNLVAAAAQDMREAGLNANHVQVDITDQESLTSAYDGIAAESGRLDVLVNAAGVGDSRMFLDVDDAHYKKVIDVNVRGTWNSCRAAVPHMLSNKHGRIINFGSISGPIVADPGWTVYALSKGAIFGFTKALASEFAGQNILVNAILPGSMDTPMMRAAAADTNPADPQSVIDEIAAAVPLKRLGTIDDAGNLALFLASDLASYLTGQAIVLDGAFTLAEYQS
>biolip__5itvA Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh
MIMNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYMTGSAITADGGYTAQ
>metacyc__MONOMER-19127 dihydroanticapsin dehydrogenase (EC 1.1.1.385) (Bacillus subtilis (strain 168))
MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYMTGSAITADGGYTAQ
>PDB_6ihh_A Crystal structure of rasadh f12 from ralstonia.Sp in complex with NADPH and a6o
MYRLLNKTAVITGGNSGIGLATAKRFVAEGAYVFIVGRRRKELEQAAAEIGRNVTAVKADVTKLEDLDRLYAIVREQRGS
IDVLFANSGAVEQKTLEEITPEHYDRTFDVNVRGLIFTVQKALPLLRDGGSVILTSSVAGVLGLQAHDTYSAAKAAVRSL
ARTWTTELKGRSIRVNAVSPGAIDTPSLENNVSTQEEADELRAKAAAATPLGRVGRPEELAAAVLFLASDDSSYVAGIEL
FVDGGLTQV
>biolip__6b9uA Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from brucella melitensis complexed with nadh
SLEGKVALITGAGSGFGEGMAKRFAKGGAKVVIVDRDKAGAERVAGEIGDAALAVAADISKEADVDAAVEAALSKFGKVDILVNNAGIGHKPQNAELVEPEEFDRIVGVNVRGVYLMTRKLIPHFKENGAKGQECVILNVASTGAGRPRPNLAWYNATKGWVVSVTKALAIELAPAKIRVVALNPVAGETPLLTTFMRKKFRDSIPMGRLLKPDDLAEAAAFLCSPQASMITGVALDVDGGRSI
>biolip__5b4tA Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and a substrate d-3- hydroxybutyrate
MLKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLNADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHGTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSSAAADQMTGTTLSLDGGWTAR
>BRENDA__A0JC04 octanol dehydrogenase (EC 1.1.1.73) (Ogataea wickerhamii)
MSYNFHNKVAVVTGALSGIGLSVAKKFLQLGAKVTISDVSGEKKYHETVVALKAQNLNTDNLHYVQADSSKEEDNKKLISETLATFGGLDIVCANAGIGKFAPTHETPFDVWKKVIAVNLNGVFLLDKLAINYWLEKSKPGVIVNMGSVHSFVAAPGLAHYGAAKGGVKLLTQTLALEYASHGIRVNSVNPGYISTPLIDEVPKERLDKLVSLHPIGRLGRPEEVADAVAFLCSQEATFINGVSLPVDGGYTAQ
>PDB_3w8d_A Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate
MLKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLNADLSDAQATRDFIAKAAEA
LGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHGTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKH
GVVGLTKVTALENAGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSS
AAADQMTGTTLSLDGGWTAR
>PDB_3vdr_A Crystal structure of d-3-hydroxybutyrate dehydrogenase, prepared in the presence of the substrate d-3-hydroxybutyrate and NAD(+)
MLKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLNADLSDAQATRDFIAKAAEA
LGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHGTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKH
GVVGLTKVTALENAGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSS
AAADQMTGTTLSLDGGWTAR
>PDB_3vdq_A Crystal structure of alcaligenes faecalis d-3-hydroxybutyrate dehydrogenase in complex with NAD(+) and acetate
MLKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLNADLSDAQATRDFIAKAAEA
LGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHGTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKH
GVVGLTKVTALENAGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSS
AAADQMTGTTLSLDGGWTAR
>biolip__4nbtA Crystal structure of fabg from acholeplasma laidlawii
KKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVEGMYLNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLTRLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNAIAPGYIMTDILKTVPQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQTINVNGGMRL
>ENA__AFO85456.1 reductase/oxidase (Marinactinospora thermotolerans)
MPQRASGALKGRIAVVTGASRGIGRAIALRLARDGAAVVAGYHQDKAGADAAVAEIEAAGGRAQAVRVDLADLADIERLFDVAVARFGAVDILVNNAGTVTAGPIAAVTEAEYDRVMAVNTKGVLFALRQAGLRLRDGGRVINVSSLNTVMPEAEAAVYTGSKAAVEGFTRVAAREFAERGITVNTVSPGPVQTDLLKGNPPDVLEQIAADTPLGRLGRPSDIADVVAFLAGPDARWLTGQNLRATGGLA
>BRENDA__Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (Staphylococcus aureus)
MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>SwissProt__P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 (Staphylococcus aureus (strain Mu50 / ATCC 700699))
MKMTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>metacyc__HS08987-MONOMER 3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.104) (Homo sapiens)
MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL
>biolip__2ag5A Crystal structure of human dhrs6
MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSLG
>BRENDA__Q9WYD3 D-arabinitol 2-dehydrogenase (EC 1.1.1.250) (Thermotoga maritima)
MNILEKLFSLKRKVALVTGGGQGIGKAIAQALAAAGAAVLIMDINEETARRTVEEIKEKGGEADFYVGDVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSAKAEFHAMKERKYGKIINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLAAEWAPYGIRVNSISPGYIRTPLIESPNVKDLVPLWLDMIPLGRLGEVDDLIGAAIFLASPASDYMTGHDLVIDGGYTVW
>PDB_3sj7_A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
TKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSL
DVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIG
LTKSAARELASRGITVNAVAPGFIVSDMTDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>metacyc__MONOMER-14379 S-1-(4-hydroxyphenyl)-ethanol dehydrogenase (Aromatoleum aromaticum (strain EbN1))
MKQNLSGKVAYVSGAASGIGAAIARVFAAEGASVLLGDVQVERGETVAAHIREQGGRALFIHHDVSDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAGVILGHKHAIRTMRPGGSAGKGGSIINLSSVAGLIGTPALGVYSATKGAVRLLSKAAAVECGRLGYGIRVNSIHPGLVDTDMGVKLVDDFVGLGVFADRETALRQMLETYPIGRTGVPGDIAGTALFLASEQSSWITGTEIVVDGGMTIS
>BRENDA__Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (Plasmodium falciparum)
MIKMSVLHRFYLFFLFTKFFHCYKISYVLKNAKLAPNHAIKNINSLNLLSENKKENYYYCGENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAPGFISSDMTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDGGLSP
>metacyc__MONOMER-20560 levodione reductase monomer (Leifsonia aquatica)
MTATSSPTTRFTDRVVLITGGGSGLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLETAPDAEVLTTVADVSDEAQVEAYVTATTERFGRIDGFFNNAGIEGKQNPTESFTAAEFDKVVSINLRGVFLGLEKVLKIMREQGSGMVVNTASVGGIRGIGNQSGYAAAKHGVVGLTRNSAVEYGRYGIRINAIAPGAIWTPMVENSMKQLDPENPRKAAEEFIQVNPSKRYGEAPEIAAVVAFLLSDDASYVNATVVPIDGGQSAAY
>biolip__4wecA Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis
SMDLTQRLAGKVAVITGGASGIGLATGRRLRAEGATVVVGDIDPTTGKAAADELEGLFVPVDVSEQEAVDNLFDTAASTFGRVDIAFNNAGISPPEDDLIENTDLPAWQRVQDINLKSVYLSCRAALRHMVPAGKGSIINTASFVAVMGSATSQISYTASKGGVLAMSRELGVQYARQGIRVNALCPGPVNTPLLQELFAKDPERAARRLVHIPLGRFAEPEELAAAVAFLASDDASFITGSTFLVDGGISSAYVTPL
>biolip__1iy8A Crystal structure of levodione reductase
RFTDRVVLITGGGSGLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLETAPDAEVLTTVADVSDEAQVEAYVTATTERFGRIDGFFNNAGIEGKQNPTESFTAAEFDKVVSINLRGVFLGLEKVLKIMREQGSGMVVNTASVGGIRGIGNQSGYAAAKHGVVGLTRNSAVEYGRYGIRINAIAPGAIWTPMVENSMKQLDPENPRKAAEEFIQVNPSKRYGEAPEIAAVVAFLLSDDASYVNATVVPIDGGQSAAY
>BRENDA__Q9I1X3 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) (Pseudomonas aeruginosa)
MSEQRQTLPAQHQDQRPGHESQMQPKPEFVSADYRPAAKLEGKVALVTGGDSGIGRAVAVAFAREKADVVLVYLDENEDAAKTREIIESLGRQCLAFAGDVADAGFCRQVVDTLRQKWGRLDVLVNNAGEQHPQARLEDISEEQWEKTFRTNIFGMFQLTKAALPLMGKGGAIINTTSITAYKGNPQLIDYSSTKGAITSFTRSLSMNLVNRGIRVNAVAPGPIWTPLIPSTFSAEKVAHFGADTPMGRPGQPEELAASYVYLACNDSSYVSGQVLHVNGGTVVNG
>SwissProt__Q9ZW03 Tropinone reductase homolog At2g29150; EC 1.1.1.- (Arabidopsis thaliana (Mouse-ear cress))
MAKAGENSRDKSRWSLEGMTALVTGGSKGLGEAVVEELAMLGARVHTCARDETQLQERLREWQAKGFEVTTSVCDVSSREQREKLMETVSSVFQGKLNILVNNAGTGIIKPSTEYTAEDYSFLMATNLESAFHLSQIAHPLLKASGSGSIVFMSSVAGLVHTGASIYGASKGAMNQLGRSLACEWASDNIRVNSVCPWVITTPLTSFIFSDEKLRKAVEDKTPMGRVGEANEVSSLVAFLCFPAASYITGQTICVDGGASVNGFSFKP
>SwissProt__Q9ZW18 Senescence-associated protein 13; Tropinone reductase homolog SAG13; EC 1.1.1.- (Arabidopsis thaliana (Mouse-ear cress))
MAKEGGLGENSRWSLGGMTALVTGGSKGIGEAVVEELAMLGAKVHTCARDETQLQERLREWQAKGFQVTTSVCDVSSRDQRVKLMETVSSLYQGKLNILVNNVGTSIFKPTTEYTAEDFSFVMATNLESAFHLSQLAHPLLKASGSGSIVLISSAAGVVHVNVGSIYGATKGAMNQLARNLACEWASDNIRTNSVCPWYITTPLSNDFFDEEFKKEAVRTTPMGRVGEANEVSPLVAFLCLPSASYITGQTICVDGGATVNGFSFKTMP
>SwissProt_Q9LBG2 Levodione reductase; (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase; EC 1.1.1.- from Leifsonia aquatica (Corynebacterium aquaticum)
MTATSSPTTRFTDRVVLITGGGSGLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLETAPDAEVLTTVADVSDEAQVE
AYVTATTERFGRIDGFFNNAGIEGKQNPTESFTAAEFDKVVSINLRGVFLGLEKVLKIMREQGSGMVVNTASVGGIRGIG
NQSGYAAAKHGVVGLTRNSAVEYGRYGIRINAIAPGAIWTPMVENSMKQLDPENPRKAAEEFIQVNPSKRYGEAPEIAAV
VAFLLSDDASYVNATVVPIDGGQSAAY
>PDB_1zk1_A Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and NAD
SNRLDGKVAIITGGTLGIGLAIATKFVEEGAKVMITDRHSDVGEKAAKSVGTPDQIQFFQHDSSDEDGWTKLFDATEKAF
GPVSTLVNNAGIAVNKSVEETTTAEWRKLLAVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGFVGDPSLGAYNASKG
AVRIMSKSAALDCALKDYDVRVNTVHPGYIKTPLVDDLPGAEEAMSQRTKTPMGHIGEPNDIAYICVYLASNESKFATGS
EFVVDGGYTAQ
>PDB_1zjz_A Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and NAD
SNRLDGKVAIITGGTLGIGLAIATKFVEEGAKVMITDRHSDVGEKAAKSVGTPDQIQFFQHDSSDEDGWTKLFDATEKAF
GPVSTLVNNAGIAVNKSVEETTTAEWRKLLAVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGFVGDPSLGAYNASKG
AVRIMSKSAALDCALKDYDVRVNTVHPGYIKTPLVDDLPGAEEAMSQRTKTPMGHIGEPNDIAYICVYLASNESKFATGS
EFVVDGGYTAQ
>PDB_1zjy_A Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and nadh
SNRLDGKVAIITGGTLGIGLAIATKFVEEGAKVMITDRHSDVGEKAAKSVGTPDQIQFFQHDSSDEDGWTKLFDATEKAF
GPVSTLVNNAGIAVNKSVEETTTAEWRKLLAVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGFVGDPSLGAYNASKG
AVRIMSKSAALDCALKDYDVRVNTVHPGYIKTPLVDDLPGAEEAMSQRTKTPMGHIGEPNDIAYICVYLASNESKFATGS
EFVVDGGYTAQ
>metacyc__MONOMER-19696 chenodeoxycholate 3&alpha;-dehydrogenase (EC 1.1.1.392) (Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9))
MFMMLKNKVAIVTGGTRGIGFAVVKKFIENGAAVSLWGSRQETVDQALEQLKELYPDAKISGKYPSLKDTAQVTAMINQVKEEFGAVDILVNNAGISQSTSFYNYQPEEFQKIVDLNVTAVFNCSQAAAKIMKEQGGGVILNTSSMVSIYGQPSGCGYPASKFAVNGLTKSLARELGCDNIRVNAVAPGITRTDMVAALPEAVIKPLIATIPLGRVGEPEDIANAFLFLASDMASYVTGEILSVDGAARS
>biolip__6y0sAAA 6y0sAAA
SNRLDGKVAIITGGTLGIGLAIATKFVEEGAKVMITGRHSDVGEKAAKSVGTPDQIQFFQHDSSDEDGWTKLFDATEKAFGPVSTLVNNAGIAVNKSVEETETAEWRKLLAVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGFVGDPSLGAYNASKGAVRIMSKSAALDCALKDYDVRVNTVHPGYIKTPLVDDLPGAEEAMSQRTKTPMGHIGEPNDIAYICVYLASNESKFATGSEFVVDGGYTAQ
>SwissProt__A7DY56 Tropinone reductase; EC 1.1.1.206; EC 1.1.1.236 (Cochlearia officinalis (Common scurvygrass))
MANLRESSRDKSRWSLEGMTALVTGGSKGIGEAVVEELAMLGARVHTCARDETQLQESLREWQAKGFQVTTSVCDVSSRDQREKLMETVSSLFQGKLNILVNNAGTCITKPTIDYTSEDFSFLMSTNLESSFHLSQLAHPLLKSSGLGSIVLISSVASVVHVNVGSIYGATKGAMNQLARNLACEWASDSIKVNSVCPGFISTPLASNYFRNEEFKKEVENIIPTGRVGEANEVSSLVAYLCLPAASYVTGQTICVDGGFSVNGFTFKSLPLR
>metacyc__MONOMER-21160 3&alpha;-hydroxysteroid dehydrogenase (EC 1.1.1.52) (Eggerthella sp. CAG:298)
MGKLEGKVAIVTGGTRGIGFGIVEKFLAEGAKVALFGSRQETVDAALEKIKQNDPEAPVMGLHPALTDPDEIAAAFKSVVDTFGSLDILANNAGTDSRTKLVDYTLEEFQKVMRLNVEATFVCSQAAARIMIEQGTGGAIINTSSMVSIYGQPAGCAYPTSKFAVNGLTKSLARELAPHKIRVNAVAPGVTHTDMVDALPREVIEPLIKTIPLGRMGEPEDIANAFAFLASDEASYISGDVLSVDGLSRS
>metacyc__MONOMER-19584 3-hydroxykynurenate reductase/dehydratase (Streptomyces sp. SNA15896)
MSVSGKTVVVTGAGSGIGRAACELLCRAGARVGAIGRREKLLHALRDELHAEPGELVALPADVGSASEVEAAVRALTERCGPVTGVVNNAGLARFAPIDSASLSDLDAMFAVHLRGPVNTLRACLPALRAHRGAVVNVSSVGGALAMPNRSLYGATKAAVNSLTRSWARELAPRIRVNAILPGPVDTPMYADLGLTDTQTETLRADLLASTPLGRFGEPHEVARWIALLLDDDMSGWITGALVPVDGGRTT
>biolip__4b79A The aeropath project and pseudomonas aeruginosa high-throughput crystallographic studies for assessment of potential targets in early stage drug discovery.
MVFQHDIYAGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRHPRIRREELDITDSQRLQRLFEALPRLDVLVNNAGISRDREEYDLATFERVLRLNLSAAMLASQLARPLLAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWIDTPKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAVDGGYLCA
>biolip__7ejhA Crystal structure of kred mutant-f147l/l153q/y190p/l199a/m205f/m206f and 2-hydroxyisoindoline-1,3-dione complex
GMTDRLKGKVAIVTGGTLGIGLAIADKFVEEGAKVVITGRHADVGEKAAKSIGGTDVIRFVQHDASDEAGWTKLFDTTEEAFGPVTTVVNNAGIAVSKSVEDTTTEEWRKLLSVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGLVGDPTQGAYNASKGAVRIMSKSAALDCALKDYDVRVNTVHPGPIKTPLVDDAEGAEEFFSQRTKTPMGHIGEPNDIAWICVYLASDESKFATGAEFVVDGGYTAQ
>BRENDA__Q9HK51 aldose 1-dehydrogenase (NAD+) (EC 1.1.1.121) (Thermoplasma acidophilum)
MFSDLRDKVVIVTGASMGIGRAIAERFVDEGSKVIDLSIHDPGEAKYDHIECDVTNPDQVKASIDHIFKEYGSISVLVNNAGIESYGKIESMSMGEWRRIIDVNLFGYYYASKFAIPYMIRSRDPSIVNISSVQASIITKNASAYVTSKHAVIGLTKSIALDYAPLLRCNAVCPATIDTPLVRKAAELEVGSDPMRIEKKISEWGHEHPMQRIGKPQEVASAVAFLASREASFITGTCLYVDGGLSIRAPISTPE
>PDB_7eji_B Crystal structure of kred f147l/l153q/y190p/l199a/m205f/m206f variant and methyl methacrylate complex
TDRLKGKVAIVTGGTLGIGLAIADKFVEEGAKVVITGRHADVGEKAAKSIGGTDVIRFVQHDASDEAGWTKLFDTTEEAF
GPVTTVVNNAGIAVSKSVEDTTTEEWRKLLSVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGLVGDPTQGAYNASKG
AVRIMSKSAALDCALKDYDVRVNTVHPGPIKTPLVDDAEGAEEFFSQRTKTPMGHIGEPNDIAWICVYLASDESKFATGA
EFVVDGGYTAQ
>SwissProt__Q9ZW19 Tropinone reductase homolog At2g29360; EC 1.1.1.- (Arabidopsis thaliana (Mouse-ear cress))
MAKTGESLRDKPRWSLVGMTALVTGGSKGIGEAVVEELATLGARIHTCARDETQLQESLRKWQAKGFQVTTSVCDVSSRDKREKLMETVSTIFEGKLNILVNNVGTCIVKPTLQHTAEDFSFTMATNLESAFHLSQLAHPLLKASGSGSIVLISSVSGVVHVNGASIYGVSKGAMNQLGRNLACEWASDNIRTNSVCPWFIETPLVTESLSNEEFRKEVESRPPMGRVGEVNEVSSLVAFLCLPAASYITGQTICVDGGFTVNGFSFKPLP
>BRENDA__Q5SLC4 aldose 1-dehydrogenase (NAD+) (EC 1.1.1.121) (Thermus thermophilus)
MGLFAGKGVLVTGGARGIGRAIAQAFAREGALVALCDLRPEGKEVAEAIGGAFFQVDLEDERERVRFVEEAAYALGRVDVLVNNAAIAAPGSALTVRLPEWRRVLEVNLTAPMHLSALAAREMRKVGGGAIVNVASVQGLFAEQENAAYNASKGGLVNLTRSLALDLAPLRIRVNAVAPGAIATEAVLEAIALSPDPERTRRDWEDLHALRRLGKPEEVAEAVLFLASEKASFITGAILPVDGGMTASFMMAGRPV
>SwissProt__G9FRD7 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- (Clostridium sardiniense (Clostridium absonum))
MKRLEGKVAIVTSSTRGIGRASAEALAKEGALVYLAARSEELANEVIADIKKQGGVAKFVYFNAREEETYTSMVEKVAEAEGRIDILVNNYGGTNVNLDKNLTAGDTDEFFRILKDNVQSVYLPAKAAIPHMEKVGGGSIVNISTIGSVVPDISRIAYCVSKSAINSLTQNIALQYARKNIRCNAVLPGLIGTRAALENMTDEFRDSFLGHVPLNRVGRPEDIANAVLYYASDDSGYVTGMIHEVAGGFALGTPQYSEYCPR
>reanno__WCS417_GFF2259 Sorbitol dehydrogenase (EC 1.1.1.14) (Pseudomonas simiae WCS417)
MKRLEGKSALITGSARGIGRAFAQAYIAEGATVAIADIDLQRAQATAAELGPQAYAVAMDVTDQASIDGAITAVVAQAGKLDILINNAALFDLAPIVDITRDSYDRLFSINVAGTLFTLQAAARQMIRQGHGGKIINMASQAGRRGEPLVAIYCATKAAVISLTQSAGLNLIKQGINVNAIAPGVVDGEHWDGVDALFAKHEGLAPGEKKQRVGAEVPFGRMGTAEDLTGMAIFLASKEADYVVAQTYNVDGGNWMN
>SwissProt__D4YYG1 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; 2,5-DDOL dehydrogenase; EC 1.1.1.- (Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum))
MSDLSGKTIIVTGGGSGIGRATVELLVASGANVAVADINDEAGEAVVAASGGKAAYFRCDIAQEEDVKALVAQTLAAFGGLDGAFNNAAIPQAGLPLAEVSLERFRQSMDINVTGTFLCMKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAAADYGKHGIRVNALVPGAVRTPMLQRAMDNDAGLEPYLNSIHPIGRFSEPHEQAQAAVWLLSDAASFVTGSCLAADGGFTAI
>PDB_1zk4_A Structure of r-specific alcohol dehydrogenase (wildtype) from lactobacillus brevis in complex with acetophenone and NADP
SNRLDGKVAIITGGTLGIGLAIATKFVEEGAKVMITGRHSDVGEKAAKSVGTPDQIQFFQHDSSDEDGWTKLFDATEKAF
GPVSTLVNNAGIAVNKSVEETTTAEWRKLLAVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGFVGDPSLGAYNASKG
AVRIMSKSAALDCALKDYDVRVNTVHPGYIKTPLVDDLPGAEEAMSQRTKTPMGHIGEPNDIAYICVYLASNESKFATGS
EFVVDGGYTAQ
>metacyc__MONOMER-323 CymB (Pseudomonas putida)
MRLKDKVAIVTGAATGIGNAIVRSYLAEGAKVVIADVKGAEAAAAELGEDLALGVFADVSDPDSTKQMAKAALDRFGKIDVLVNNAGIFTGLNYVPMESISVADWDKLYSVNVKGPWLCASAVSAAMREGGGGKIINIASVIAHIGAPFMLHYVSSKGAVAAMTRAMAREFATTKAGISVNSISPGYTHSENALANAQQHEQFEGVSASMRAIDRPQVPADIAGVALWLASDEASYVNGQNIVVDGGIYMSL
>SwissProt__Q9ZW16 Tropinone reductase homolog At2g29330; EC 1.1.1.- (Arabidopsis thaliana (Mouse-ear cress))
MDKRWSLQGLTALVTGGASGIGHAIVEELAGFGAKIHVCDISKTLLNQSLSEWEKKGFQVSGSVCDASNRLERETLMQTVTTIFDGKLNILVNNVGTIRTKPTIEYEAEDFSFLISTNLESAYHLSQLSHPLLKASGNGIITFISSAAGIVSFDAASIYGLTKGALNQLARNLACEWAKDGIRANAVAPNFITTALAKPFLEDAGFNEILSSRTPLGRAGEPREVASLVAFLCLPAASYITGQTICVDGGLTVNGFSYQP
>metacyc__MONOMER-13284 2-(S)-hydroxypropyl-CoM dehydrogenase subunit (EC 1.1.1.269) (Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2))
MLDAEVIAITGGAAGIGLAVAHAAIRAGARVALIDRDGACAQRAAAEFGAAAWGVGADVTDEAAITAAMAGAQRALGPLTGLVNNAGIAGFGSVHATEVETWSRIMAVNVTGTFLASKAALFGMLERGRGAIVNFGSVAGLVGIPTMAAYCAAKGAVVNLTRQMAADYSGRGIRVNVVCPGTVAGTDMGRQLLGTDCDPELEARRLAKYPMGRFGTPEDIAEAAVFLLSTKAAFVTGSVLAVDGGMTAI
>biolip__4nbuB Crystal structure of fabg from bacillus sp
HMSRLQDKVAIITGAANGIGLEAARVFMKEGAKVVIADFNEAAGKEAVEANPGVVFIRVDVSDRESVHRLVENVAERFGKIDILINNAGITRDSMLSKMTVDQFQQVINVNLTGVFHCTQAVLPYMAEQGKGKIINTSSVTGTYGNVGQTNYAAAKAGVIGMTKTWAKELARKGINVNAVAPGFTETAMVAEVPEKVIEKMKAQVPMGRLGKPEDIANAYLFLASHESDYVNGHVLHVDGGIMM