>WP_068331063.1 NCBI__GCF_001650345.1:WP_068331063.1
MSLFMSLVGMAVLLAIAVLLSDNRKAINLRTVGGAFAIQFCLGAFVLYVPVGRDVLYGMSQAVANVISYGNDGINFLFGGLTSDKMFEVFGGGGFVFALRVLPVIVFFSALISVLYYMGIMQFVINILGGGLQKALGTSRAESMSATANIFVGQTEAPLVIRPFVPKMTQSELFAVMCGGLASVAGGVLAGYASMGVPLEYLIAASFMAAPGGLLFAKIIKPETEEPIEQLAGDDANGDDKPANVIDAAAAGASSGMQLALNVGAMLLAFIGLIALINGMLGGIGGWFGMPELTLELILGYVFSPLAFLIGVPWEEATIAGSFIGQKLVVNEFVAYLNFAPYLADGAEVVLSAKTEAIISFALCGFANLSSVAILLGGLGGLAPSRRHDIARFGMKAVAAGTLSNLMSATIAGLFVAVNAM
>TCDB__Q9KPL5 Concentrative nucleoside transporter, CNT, of 418 aas and 12 TMSs. A repeat-swapped model of VcCNT predicts that nucleoside transport occurs via a mechanism involving an elevator-like substrate binding domain movement across the membrane (Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961))
MSLFMSLIGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDNEDITLDGGDDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFLSF
>PDB_4pd7_A Structure of vccnt bound to zebularine
SLFMSLIGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGL
VSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVV
RPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGG
ASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANE
FVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIA
GFFL
>PDB_3tij_A Crystal structure of a concentrative nucleoside transporter from vibrio cholerae
SLFMSLIGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGL
VSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVV
RPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGG
ASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANE
FVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIA
GFFL
>biolip__4pb1A Structure of vccnt-7c8c bound to ribavirin
SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL
>PDB_4pda_A Structure of vccnt-7c8c bound to cytidine
SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGL
VSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVV
RPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGG
ASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANE
FVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIA
GFFL
>PDB_4pd9_A Structure of vccnt-7c8c bound to adenosine
SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGL
VSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVV
RPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGG
ASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANE
FVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIA
GFFL
>PDB_4pd8_A Structure of vccnt-7c8c bound to pyrrolo-cytidine
SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGL
VSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVV
RPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGG
ASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANE
FVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIA
GFFL
>PDB_4pb2_A Structure of vccnt-7c8c bound to 5-fluorouridine
SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGL
VSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVV
RPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGG
ASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANE
FVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIA
GFFL
>PDB_4pd5_A Crystal structure of vccnt-7c8c bound to gemcitabine
LFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLV
SGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVR
PFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGA
SAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEF
VAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAG
FFL
>reanno__ANA3_7023819 nucleoside permease (cytidine, inosine, uridine, or thymidine) (Shewanella sp. ANA-3)
MNILMSLVGVVVLLAIGFLLSNNKKAINLRTVGGALAIQAAFGGFVLYVPVGKDILKSVSDAVSSVIGYAQNGIGFLFGDLANFKLGFIFAVNVLPVIVFFSSLIAVLYYLGIMQWIIRIIGGGLQKALGTSRTESMSATANIFVGQTEAPLVVRPFIPTMTQSELFAIMVGGLASIAGSVLAGYAQMGVPIEYLVAASFMAAPGGLLMAKLMHPETEVAKNDMDELPEDPDKPANVLDAAAAGASSGMHLALNVGAMLLAFVGLIAMINGIIGGVGGWFGVEGLTLELILGYIFMPLAFLIGVPWNEALVAGSFIGQKIVVNEFVAYLNFAPYLKDIADGGMIVADTGLAMTDRTKAIISFALCGFANLSSIAILLGGLGAMAPNRRHDLAKLGIRAVIAGSLANLMSATIAGLFLAI
>PDB_5l26_A Structure of cntnw in an inward-facing substrate-bound state
PRMVVLHSLLGMAVLIAIAVLLSTDRKAINIRTVAGAFLIQVALGALVLYVPQGRDMLGEASKTISNVIAYGNNGVDFLF
GGLVSEKMFEVFGGGGFVFALRVLPMIVFFSSLMAVLYYIGVMQLLIKVIGGFLQKMLGTSKAESMSAAANIFVGQTEAP
LVVRPYIRRMTESELFAVMSGGLASVAGSVLAGYVQMGVPLPYLIAASFMAAPGGLLFAKLLVPETERTQNDAEVLAENE
DEKPTNVIDAAASGAVTGAQIAIAVGASLLAFVALIAMINGIIGGVGGDLTLQAILGWLFSPLAWVIGVPWSEAGIAGSL
IGQKVVINEFVAYSEFVKYLKPEAAVQLSDTTKAIISFALCGFANLGSIAVLVGGLSIMAPKRRKDVARLGIKAVVAGSL
SNLMSAVIAGLFTGLSGAS
>biolip__5l2aA Structure of cntnw n149s,f366a in an outward-facing state
VPRMVVLHSLLGMAVLIAIAVLLSTDRKAINIRTVAGAFLIQVALGALVLYVPQGRDMLGEASKTISNVIAYGNNGVDFLFGGLVSEKMFEVFGGGGFVFALRVLPMIVFFSSLMAVLYYIGVMQLLIKVIGGFLQKMLGTSKAESMSAAASIFVGQTEAPLVVRPYIRRMTESELFAVMSGGLASVAGSVLAGYVQMGVPLPYLIAASFMAAPGGLLFAKLLVPETERTQNDAEVLAENEDEKPTNVIDAAASGAVTGAQIAIAVGASLLAFVALIAMINGIIGGVGGWFGHGDLTLQAILGWLFSPLAWVIGVPWSEAGIAGSLIGQKVVINEFVAYSEFVKYLKPEAAVQLSDTTKAIISFALCGAANLGSIAVLVGGLSIMAPKRRKDVARLGIKAVVAGSLSNLMSAVIAGLFTGLS
>metacyc__HP_RS05795-MONOMER purine nucleobase/nucleoside transporter (Helicobacter pylori (strain ATCC 700392 / 26695))
MIFSSLFSVVGMAVLFLIAWVFSSNKRAINYRTIVSAFVIQVALGALALYVPLGREMLQGLASGIQSVISYGYEGVRFLFGNLAPNAKGDQGIGGFVFAINVLAIIIFFASLISLLYYLKIMPLFINLIGGALQKCLGTSRAESMSAAANIFVAHTEAPLVIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADVSIEKHVNAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLLKPLAFMLGIPWSQAGIAGEIIGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTLSNFMSATIAGLFIGLNAH
>ecocyc__YEIJ-MONOMER putative nucleoside transporter (Escherichia coli K-12 substr. MG1655)
MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGGIMLWLPPGRWVAEKVAFGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVLPAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDRLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFARLLSPATESSQVSFNNLSFTETPPKSIIEAAATGAMTGLKIAAGVATVVMAFVAIIALINGIIGGVGGWFGFEHASLESILGYLLAPLAWVMGVDWSDANLAGSLIGQKLAINEFVAYLNFSPYLQTAGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA
>ecocyc__YEIM-MONOMER putative pseudouridine transporter (Escherichia coli K-12 substr. MG1655)
MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGGIMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETPPKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA
>SwissProt__Q9ERH8 Solute carrier family 28 member 3; Concentrative Na(+)-nucleoside cotransporter 3; CNT 3; mCNT3 (Mus musculus (Mouse))
MSRADPGKNSEPSESKMSLELRPTAPSDLGRSNEAFQDEDLERQNTPGNSTVRNRVVQSGEQGHAKQDDRQITIEQEPLGNKEDPEDDSEDEHQKGFLERKYDTICEFCRKHRVVLRSTIWAVLLTGFLALVIAACAINFHRALPLFVITLVTIFFVIWDHLMAKYEQRIDDFLSPGRRLLDRHWFWLKWVVWSSLILAIILWLSLDTAKLGQQNLVSFGGLIMYLILLFLFSKHPTRVYWRPVFWGIGLQFLLGLLILRTRPGFVAFDWMGRQVQTFLGYTDTGARFVFGEKYTDHFFAFKILPIVVFFSTVMSMLYYLGLMQWIIRKVGWLMLVTMGSSPIESVVAAGNIFIGQTESPLLVQPYLPHVTKSELHTIMTAGFATIAGSVLGAYISFGVSSTHLLTASVMSAPAALAVAKLFWPETEKPKITLKSAMKMENGDSRNLLEAASQGASSSIPLVANIAANLIAFLALLSFVNSALSWFGSMFNYPELSFELICSYIFMPFSFMMGVDWQDSFMVAKLIGYKTFFNEFVAYDHLSKLINLRKAAGPKFVNGVQQYMSIRSETIATYALCGFANFGSLGIVIGGLTSIAPSRKRDIASGAMRALIAGTIACFMTACIAGILSDTPVDINCHHVLENGRVLSNTTEVVSCCQNLFNSTVAKGPNDVVPGGNFSLYALKSCCNLLKPPTLNCNWIPNKL
>biolip__8tz1A Cryo-em structure of bovine concentrative nucleoside transporter 3 in complex with ribavirin
ERMCGRMSDFCREHKTTLRYIIWGILIAGYLALVIAACVMNFHRALPLFVITVVAIFFVVWDHLMAKYESQIARFLSPGQRLLDSHWFWLKWVIWGCLILGVILWLVFDTAKLGQQQLVSFGGLIIYTSLTFLFSKHPTKVYWRPVFWGIGLQFLLGLLILRTEPGFMAFDWLGKQVQTFLGYSDAGASFVFGEKYTDHFFAFKVLPIVIFFSTVMSMLYYLGLMQWIIRKVGWVMLVTMGTSPVESVVASGNIFIGQTESPLLVRPYLPYVTKSELHAIMTAGFSTIAGSVLGAYISFGVSSSHLLTASVMSAPAALAISKLFWPETETPKINLKNAMKMESGDSRNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWLGNMFDYPQLSFEVICSYVFMPFAFMMGVDWQDSFMVAKLIGYKTFFNEFVAYQQLSKLISLRQVGGPKFVDGVQQYMSMRSEAISTYALCGFANFGSLGIVIGGLTSMAPSRKRDITAGAMRALIAGTIACFLTACIAGMLTNTP
>PDB_8tz7_A Cryo-em structure of bovine concentrative nucleoside transporter 3 in complex with molnupiravir, condition 1, int1-int1-int1 conformation
ERMCGRMSDFCREHKTTLRYIIWGILIAGYLALVIAACVMNFHRALPLFVITVVAIFFVVWDHLMAKYESQIARFLSPGQ
RLLDSHWFWLKWVIWGCLILGVILWLVFDTAKLGQQQLVSFGGLIIYTSLTFLFSKHPTKVYWRPVFWGIGLQFLLGLLI
LRTEPGFMAFDWLGKQVQTFLGYSDAGASFVFGEKYTDHFFAFKVLPIVIFFSTVMSMLYYLGLMQWIIRKVGWVMLVTM
GTSPVESVVASGNIFIGQTESPLLVRPYLPYVTKSELHAIMTAGFSTIAGSVLGAYISFGVSSSHLLTASVMSAPAALAI
SKLFWPETETPKINLKNAMKMESGDSRNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWLGNMFDYPQLSFE
VICSYVFMPFAFMMGVDWQDSFMVAKLIGYKTFFNEFVAYQQLSKLISLRQVGGPKFVDGVQQYMSMRSEAISTYALCGF
ANFGSLGIVIGGLTSMAPSRKRDITAGAMRALIAGTIACFLTACIAGMLTNTP
>PDB_8tz6_A Cryo-em structure of bovine concentrative nucleoside transporter 3 in complex with psi-6206
ERMCGRMSDFCREHKTTLRYIIWGILIAGYLALVIAACVMNFHRALPLFVITVVAIFFVVWDHLMAKYESQIARFLSPGQ
RLLDSHWFWLKWVIWGCLILGVILWLVFDTAKLGQQQLVSFGGLIIYTSLTFLFSKHPTKVYWRPVFWGIGLQFLLGLLI
LRTEPGFMAFDWLGKQVQTFLGYSDAGASFVFGEKYTDHFFAFKVLPIVIFFSTVMSMLYYLGLMQWIIRKVGWVMLVTM
GTSPVESVVASGNIFIGQTESPLLVRPYLPYVTKSELHAIMTAGFSTIAGSVLGAYISFGVSSSHLLTASVMSAPAALAI
SKLFWPETETPKINLKNAMKMESGDSRNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWLGNMFDYPQLSFE
VICSYVFMPFAFMMGVDWQDSFMVAKLIGYKTFFNEFVAYQQLSKLISLRQVGGPKFVDGVQQYMSMRSEAISTYALCGF
ANFGSLGIVIGGLTSMAPSRKRDITAGAMRALIAGTIACFLTACIAGMLTNTP
>PDB_8tz5_A Cryo-em structure of bovine concentrative nucleoside transporter 3 in complex with n-hydroxycytidine
ERMCGRMSDFCREHKTTLRYIIWGILIAGYLALVIAACVMNFHRALPLFVITVVAIFFVVWDHLMAKYESQIARFLSPGQ
RLLDSHWFWLKWVIWGCLILGVILWLVFDTAKLGQQQLVSFGGLIIYTSLTFLFSKHPTKVYWRPVFWGIGLQFLLGLLI
LRTEPGFMAFDWLGKQVQTFLGYSDAGASFVFGEKYTDHFFAFKVLPIVIFFSTVMSMLYYLGLMQWIIRKVGWVMLVTM
GTSPVESVVASGNIFIGQTESPLLVRPYLPYVTKSELHAIMTAGFSTIAGSVLGAYISFGVSSSHLLTASVMSAPAALAI
SKLFWPETETPKINLKNAMKMESGDSRNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWLGNMFDYPQLSFE
VICSYVFMPFAFMMGVDWQDSFMVAKLIGYKTFFNEFVAYQQLSKLISLRQVGGPKFVDGVQQYMSMRSEAISTYALCGF
ANFGSLGIVIGGLTSMAPSRKRDITAGAMRALIAGTIACFLTACIAGMLTNTP
>PDB_8tz4_A Cryo-em structure of bovine concentrative nucleoside transporter 3 in complex with gs-441524, subset reconstruction
ERMCGRMSDFCREHKTTLRYIIWGILIAGYLALVIAACVMNFHRALPLFVITVVAIFFVVWDHLMAKYESQIARFLSPGQ
RLLDSHWFWLKWVIWGCLILGVILWLVFDTAKLGQQQLVSFGGLIIYTSLTFLFSKHPTKVYWRPVFWGIGLQFLLGLLI
LRTEPGFMAFDWLGKQVQTFLGYSDAGASFVFGEKYTDHFFAFKVLPIVIFFSTVMSMLYYLGLMQWIIRKVGWVMLVTM
GTSPVESVVASGNIFIGQTESPLLVRPYLPYVTKSELHAIMTAGFSTIAGSVLGAYISFGVSSSHLLTASVMSAPAALAI
SKLFWPETETPKINLKNAMKMESGDSRNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWLGNMFDYPQLSFE
VICSYVFMPFAFMMGVDWQDSFMVAKLIGYKTFFNEFVAYQQLSKLISLRQVGGPKFVDGVQQYMSMRSEAISTYALCGF
ANFGSLGIVIGGLTSMAPSRKRDITAGAMRALIAGTIACFLTACIAGMLTNTP
>SwissProt__Q8VIH3 Solute carrier family 28 member 3; Concentrative Na(+)-nucleoside cotransporter 3; CNT 3; rCNT3 (Rattus norvegicus (Rat))
MSRSDPDPGKNSEPSKSKMSLELRPTAPSDQGRLNEAFQDEDLEEQNAPGNSTVRSRVVQSGEQGRAKQDDRQITIEQEPLGPKEGTEEESEDERQKGFLERKYDTVCEFCRKHRVILQHTIWAVLLTGFLALVIAACALNFHRALPLFVITLVTIFFVVWDRLMAKYEQRIDDVLSPGKRLLERHWFWLKWVVWCSLILAVILWLALDTARLGQQQLISFGGLVMYIVLLFLFSKHPTRVYWRPVFWGIGLQFLLGLLILRTRPGFVAFDWMGKQVQTFLGYTDAGAQFVFGEKYTDHFFAFKILPIVVFFSTVMSMLYYLGLMQWIIRKVGWLMLVTMGSSPIESVVAAGNIFVGQTESPLLVQPYLPHVTKSELHTIMTAGFATIAGSVLGAYISFGVSSTHLLTASVMSAPAALAVAKLFWPETEKPKITLKNAMKMENGDSRNLLEAATQGASSSIPLVANIAANLIAFLALLSFVNSALSWFGSMFDYPQLSFELICSYIFMPFSFMMGVDWQDRFMVAKLIGYKTFFNEFVAYEHLSKFINLRKAAGPKFVNGVQQYMSIRSETIATYALCGFANFGSLGIVIGGLTSIAPSRKRDIASGAMRALIAGTIACFMTACIAGMLSDTPVAINCHHVLESSKVLSNTTEVASCCQGLFNSTVARGPNDVLPGGNFSLYTLKSCCNLLKPPTLNCGWIPNIP
>SwissProt__Q9HAS3 Solute carrier family 28 member 3; Concentrative Na(+)-nucleoside cotransporter 3; CNT 3; hCNT3 (Homo sapiens (Human))
MELRSTAAPRAEGYSNVGFQNEENFLENENTSGNNSIRSRAVQSREHTNTKQDEEQVTVEQDSPRNREHMEDDDEEMQQKGCLERRYDTVCGFCRKHKTTLRHIIWGILLAGYLVMVISACVLNFHRALPLFVITVAAIFFVVWDHLMAKYEHRIDEMLSPGRRLLNSHWFWLKWVIWSSLVLAVIFWLAFDTAKLGQQQLVSFGGLIMYIVLLFLFSKYPTRVYWRPVLWGIGLQFLLGLLILRTDPGFIAFDWLGRQVQTFLEYTDAGASFVFGEKYKDHFFAFKVLPIVVFFSTVMSMLYYLGLMQWIIRKVGWIMLVTTGSSPIESVVASGNIFVGQTESPLLVRPYLPYITKSELHAIMTAGFSTIAGSVLGAYISFGVPSSHLLTASVMSAPASLAAAKLFWPETEKPKITLKNAMKMESGDSGNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWFGNMFDYPQLSFELICSYIFMPFSFMMGVEWQDSFMVARLIGYKTFFNEFVAYEHLSKWIHLRKEGGPKFVNGVQQYISIRSEIIATYALCGFANIGSLGIVIGGLTSMAPSRKRDIASGAVRALIAGTVACFMTACIAGILSSTPVDINCHHVLENAFNSTFPGNTTKVIACCQSLLSSTVAKGPGEVIPGGNHSLYSLKGCCTLLNPSTFNCNGISNTF
>TCDB__Q9UA35 Broadly selective nucleoside:Na+ cotransporter, hfCNT (transports uridine, thymidine, inosine, 3'-azido-3'deoxythymidine, 2'3'dideoxycytidine, and 2'3'dideoxyinosine) (Na+/uridine = 2) (Eptatretus stoutii (Pacific hagfish))
MSAFKARGVENPSYEDPDEKQKPDLEMSKTNGIGVDNPSYYKNPEKYLGNENEEGKSNNDNEEEEEGEEDQGAVERCVNKFYGGIHNFYKRNKKIIHYTFLGLLLVGYFALVIAACIVNFKQSLALLVLTLIAIFFFFWDLFIAKYGDKIAEALKPCQKFLDNHWSIIRWFVYGALLLAVILWLTLDTAKRGANQVIPFFGLILYILLVFIFSKHPTKVRWRIVIWGLLLQFIFGLIILRTKPGLDAFNWLGIQVQTFLKYTDAGSRFLFGDDFQDHFFAFAVLPIVIFFSTVMSMMYYLGLMQWLILKVGWLMQITMGTSPMESMVSAGNIFVGQTESPLLIRPYLADLTISEMHSVMSSGFATIAGSVLGAYISLGIPAAHLLTASVMSAPAALAISKTFWPETKKSKNSTQTSIKLEKGQENNLVEAASQGASAAVPLVANIAANLIAFLAVLAFINATLSWLGSMFNYPQFSFEIICSYVLMPFAFMMGVNYDDSFLVAELLGMKTFFNEFVAYQRLSEYIHNRESGGPLFVDGVRQYMSVRSEAIATYALCGFANFGSLGIMIGGLSSLAPHRKSDIASCGIRALIAGTIACFSTACIAGVLYIPELYCPNLLMSTLFENGTTVNTTNLMSCCTDLFKSTTMLTPKNITFTEGFNTTMLNGCCTFFPSGFNCSEVRPE
>SwissProt__Q62674 Sodium/nucleoside cotransporter 1; Concentrative nucleoside transporter 1; CNT 1; Na(+)/nucleoside cotransporter 1; Sodium-coupled nucleoside transporter 1; Solute carrier family 28 member 1 (Rattus norvegicus (Rat))
MADNTQRQRESISLTPMAHGLENMGAEFLESMEEGRLPHSHSSLPEGEGGLNKAERKAFSRWRSLQPTVQARSFCREHRQLFGWICKGLLSTACLGFLMVACLLDLQRALALLIITCVVLVFLAYDLLKRLLGSKLRRCVKFQGHSCLSLWLKRGLALAAGVGLILWLSLDTAQRPEQLVSFAGICVFLVLLFAGSKHHRAVSWRAVSWGLGLQFVLGLFVIRTEPGFIAFQWLGDQIQVFLSYTEAGSSFVFGEALVKDVFAFQVLPIIIFFSCVMSVLYYLGLMQWVILKIAWLMQVTMGTSATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSENGVKLTYGDAQNLLEAASAGAAISVKVVANIAANLIAFLAVLAFVNAALSWLGDMVDIQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGIKFFLNEFVAYQELSQYKQRRLAGAEEWLGDKKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSLVPQRRSDFSQIVLRALITGAFVSLLNACVAGILYVPRGVEVDCVSLLNQTVSSSSFEVYLCCRQVFQSTSSEFSQVALDNCCRFYNHTVCT
>SwissProt__O00337 Sodium/nucleoside cotransporter 1; Concentrative nucleoside transporter 1; CNT 1; hCNT1; Na(+)/nucleoside cotransporter 1; Sodium-coupled nucleoside transporter 1; Solute carrier family 28 member 1 (Homo sapiens (Human))
MENDPSRRRESISLTPVAKGLENMGADFLESLEEGQLPRSDLSPAEIRSSWSEAAPKPFSRWRNLQPALRARSFCREHMQLFRWIGTGLLCTGLSAFLLVACLLDFQRALALFVLTCVVLTFLGHRLLKRLLGPKLRRFLKPQGHPRLLLWFKRGLALAAFLGLVLWLSLDTSQRPEQLVSFAGICVFVALLFACSKHHCAVSWRAVSWGLGLQFVLGLLVIRTEPGFIAFEWLGEQIRIFLSYTKAGSSFVFGEALVKDVFAFQVLPIIVFFSCVISVLYHVGLMQWVILKIAWLMQVTMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDATSLIAASVMAAPCALALSKLVYPEVEESKFRREEGVKLTYGDAQNLIEAASTGAAISVKVVANIAANLIAFLAVLDFINAALSWLGDMVDIQGLSFQLICSYILRPVAFLMGVAWEDCPVVAELLGIKLFLNEFVAYQDLSKYKQRRLAGAEEWVGDRKQWISVRAEVLTTFALCGFANFSSIGIMLGGLTSMVPQRKSDFSQIVLRALFTGACVSLVNACMAGILYMPRGAEVDCMSLLNTTLSSSSFEIYQCCREAFQSVNPEFSPEALDNCCRFYNHTICAQ
>SwissProt__O62667 Sodium/nucleoside cotransporter 1; Concentrative nucleoside transporter 1; CNT 1; Na(+)/nucleoside cotransporter 1; Sodium-coupled nucleoside transporter 1; Solute carrier family 28 member 1 (Sus scrofa (Pig))
MEDNTPRQRDPISLTSVANGLENMGAELLESLEEGRAPGSDSSPAEVGGGWSKAGPEHLGRRSLQPALRVRRFCREHTQLFRWICTGLLCTAFAAFLLIACLLDFQRALALFVLFCVVLFFLAHSLLKRLLGPKLLRCVKPLRHPCLNLWFKRGLALAAFLGLVLWLVLDTAQRPEQLVSFGGICVFILLLFAGSKHHRAVSWRAVSWGLGLQFALGLFVIRTEPGFIAFQWLGDQIQIFLSYTEAGSSFVFGEALVKDVFAFQVLPIIVFFSCAMSVLYYVGLMQWVILKISWLMQATMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEIHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFKREEGVKLTYGDAQNLLEAASSGAAMSVRVVTNIAANLIAFLAVLAFINAALSWLGDMVDVQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGMKLFLNEFVAYQELSGYKQRRLAGAEEWVGSRKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSMVPQRKGDFSQIVLRALCTGACVSLVNACVAGILYVPRGAEVDCVSFLNTTLSSSSFEVYQCCRQFFQSTSLEFSPEALDNCCRFYNHTICV
>SwissProt__Q62773 Sodium/nucleoside cotransporter 2; Concentrative nucleoside transporter 2; CNT 2; rCNT2; Na(+)/nucleoside cotransporter 2; Sodium-coupled nucleoside transporter 2; Sodium/purine nucleoside cotransporter; SPNT; Solute carrier family 28 member 2 (Rattus norvegicus (Rat))
MAKSEGRKSASQDTSENGMENPGLELMEVGNLEQGKTLEEVTQGHSLKDGLGHSSLWRRILQPFTKARSFYQRHAGLFKKILLGLLCLAYAAYLLAACILNFRRALALFVITCLVIFILACHFLKKFFAKKSIRCLKPLKNTRLRLWLKRVFMGAAVVGLILWLALDTAQRPEQLISFAGICMFILILFACSKHHSAVSWRTVFWGLGLQFVFGILVIRTEPGFNAFQWLGDQIQIFLAYTVEGSSFVFGDTLVQSVFAFQSLPIIIFFGCVMSILYYLGLVQWVIQKIAWFLQITMGTTAAETLAVAGNIFVGMTEAPLLIRPYLADMTLSEIHAVMTGGFATIAGTVLGAFISFGIDASSLISASVMAAPCALALSKLVYPEVEESKFKSKEGVKLPRGEERNILEAASNGATDAIALVANVAANLIAFLAVLAFINSTLSWLGEMVDIHGLTFQVICSYVLRPMVFMMGVQWADCPLVAEIVGVKFFINEFVAYQQLSQYKNKRLSGVEEWINGEKQWISVKAEIIATFSLCGFANLTSIGITLGGLTSMVPQRKSDLCKLVVRALFTGACVSFISACMAGILYVPRGAETDCVSFLNTNFTNRTYETYVCCRELFQSTLLNGTNMPSFSGPWQDKESSLRNLAKCCDLYTSTVCA
>SwissProt__O43868 Sodium/nucleoside cotransporter 2; Concentrative nucleoside transporter 2; CNT 2; hCNT2; Na(+)/nucleoside cotransporter 2; Sodium-coupled nucleoside transporter 2; Sodium/purine nucleoside co-transporter; SPNT; Solute carrier family 28 member 2 (Homo sapiens (Human))
MEKASGRQSIALSTVETGTVNPGLELMEKEVEPEGSKRTDAQGHSLGDGLGPSTYQRRSRWPFSKARSFCKTHASLFKKILLGLLCLAYAAYLLAACILNFQRALALFVITCLVIFVLVHSFLKKLLGKKLTRCLKPFENSRLRLWTKWVFAGVSLVGLILWLALDTAQRPEQLIPFAGICMFILILFACSKHHSAVSWRTVFSGLGLQFVFGILVIRTDLGYTVFQWLGEQVQIFLNYTVAGSSFVFGDTLVKDVFAFQALPIIIFFGCVVSILYYLGLVQWVVQKVAWFLQITMGTTATETLAVAGNIFVGMTEAPLLIRPYLGDMTLSEIHAVMTGGFATISGTVLGAFIAFGVDASSLISASVMAAPCALASSKLAYPEVEESKFKSEEGVKLPRGKERNVLEAASNGAVDAIGLATNVAANLIAFLAVLAFINAALSWLGELVDIQGLTFQVICSYLLRPMVFMMGVEWTDCPMVAEMVGIKFFINEFVAYQQLSQYKNKRLSGMEEWIEGEKQWISVRAEIITTFSLCGFANLSSIGITLGGLTSIVPHRKSDLSKVVVRALFTGACVSLISACMAGILYVPRGAEADCVSFPNTSFTNRTYETYMCCRGLFQSTSLNGTNPPSFSGPWEDKEFSAMALTNCCGFYNNTVCA
>SwissProt__Q9MZT2 Sodium/nucleoside cotransporter 1; Concentrative nucleoside transporter 1; CNT 1; Na(+)/nucleoside cotransporter 1; Sodium-coupled nucleoside transporter 1; Solute carrier family 28 member 1 (Oryctolagus cuniculus (Rabbit))
MEKASGRKSLALSTAENGIENAGLELTEEGINSEQTRRMEVQGHSLSDDVRPATHQRSYLQPLTKARTFCQRHASLFKKILLGLLCLAYAAYFLAACILDFQRALALFVITCLVILVLLLHFLKKFLGKKLTRCLKPFKNSQLRLWIKRVFAGVSLVGLILWLALDTAQRPEQLISFAGICMFVLILFACSKHHSAVSWRTVFWGLGLQFVFGLLVIRTDPGFIAFQWLGDQVQIFLAYTVAGSSFVLGDTLVNDVFAFQSLPIIIFFGCVMSILYYLGLVQWVVQKIAWFLQVTMRTTATETLAVAGNIFVGMTEAPLLIRPYLADLTLSEIHAVMTSGFATISGTVLGAFISFGIDASSLISASVMGAPCALALSKLVYPEEEESKFKSKEGVKLPRGKESNVLEAASNGATDAIALVANVAANLVAFLAVLAFINAALSWLGELVDIQGLTFQVICSYILRPMVYMMGVEWTDCPMVAEMVGIKFFTNEFVAYQQLSQYKKKRLSGMEEWIDGQKQWISVRAEVITTFSLCGFANLSSIGITLGGLTSMVPHRKSDLSKVVIRALFTGSCVSFISACVAGILYVPRGAETDCVSFLSTSFTNRSYETYVCCRELFQNTYLNGTNPPSFSGAWEDKAFSAMALANCCGFYNNTVCA
>CharProtDB__CH_122469 nucleoside transporter (Eurofung) (Emericella nidulans)
MANENVLEGVPPRESPQPQDFIRHSNGHAPPAISSDNHSSYAQEAFAEKKAIPESHPLDNSSEPSGQDVEAGRKAAFKSAARRYYKSYFKHVLYAVIWLLFTGWWIAGLILHRYDLGWLVPFLLYLVITLRLIFLYVPISIFTRPVHWAWKSTASRLVSMIPEHFRIPLGALVTIATILVGSFASAEAPGNTRADRAVSLFGLLVCIFCLWLTSRNRRKVNWHTVVVGMLVQFIVALFVLRTQVGYDIFDFISMLARELLGFAQEGVDFLTTTDFESGHPYFLVTVIPAIIFFVSLVQLLYYTGVLQWAIRKLAVFFFWSMRVSGAEAVVAAASPFIGQGESAMLIKPFIAHCTMAEIHQIMCSGYATIAGSVLVSYLSMGVNAQALISSCVMSIPASLACSKLRWPEEEETLTAGRVIIPEETEDRPANLLDAFSKGAWLGIKIAGMIAATLLCIISLIGLIDGLLTWWGRYLNINNPTLTLDLIVGYICYPIAFLLGVSRDGDLLKVGKLIGLKLVANEFVAYSALQTDPQYQDLSNRSRLIATYALAGFANIGSLGNQIGVLAQLAPSRGGDVSRVAVSAMLTGAISTFTSAAIAGLLIQNEEQYMTTATS
>CharProtDB__CH_123473 cation-coupled nucleoside transporter (H(+)/nucleoside symporter) (Candida albicans)
MVSPSTDKAPSIVELTPETYQQDVSSDSIDLESGTKKLQNESALQSHEYTTNIDETSSSNTASKLTYIQKLKIRFPYYRLAIDIFIGCFFTAWWLSIVIQPKHRHQWLIPTVIWGMIMVRLITWHIKILPWLLNKVKIVWDFFTGYVYKVLSKKYQRLITGAVITVGVILLGTFVPSETEYSKRKDRAISFFGCIVAIFLLFVTSKAPSKINWNAVIGGMLMQFIIALFVLRTKCGYDVFNFISTLARELLGFAKDGVAFLTNKDVSQLGMFFFTVLPSVAFFVAFIHIWYYFGVIQWAIRKFAYFFFWTLRVSGAEAITAAASPFIGIGESAILIKDLMPYLTKAELHQIMTSGFSTISGAVLVGYIGLGLNPQALVSSCVMSIPASLAVSKLRYPELENPISSGTVMIPKVEDPEEAREKSKDEPQNVLQAFSNGATLGLRIAGTMMIQCMCIIGLVALCNGILTWFGNYWNIDHLTLELMLSYIFYPIGFLLGTPRNEILLVSKLIAYKFIQNEYVAYNLLTNEAPYNEMSKRGTLIATYACCGFANLGSLGITLGVLNTLTNNSRAKDISSSIISALFCGAIATMLSAAIAGMVMHDLNTFHIN
>SwissProt__P39141 Nucleoside permease NupC (Bacillus subtilis (strain 168))
MKYLIGIIGLIVFLGLAWIASSGKKRIKIRPIVVMLILQFILGYILLNTGIGNFLVGGFAKGFGYLLEYAAEGINFVFGGLVNADQTTFFMNVLLPIVFISALIGILQKWKVLPFIIRYIGLALSKVNGMGRLESYNAVASAILGQSEVFISLKKELGLLNQQRLYTLCASAMSTVSMSIVGAYMTMLKPEYVVTALVLNLFGGFIIASIINPYEVAKEEDMLRVEEEEKQSFFEVLGEYILDGFKVAVVVAAMLIGFVAIIALINGIFNAVFGISFQGILGYVFAPFAFLVGIPWNEAVNAGSIMATKMVSNEFVAMTSLTQNGFHFSGRTTAIVSVFLVSFANFSSIGIIAGAVKGLNEKQGNVVARFGLKLLYGATLVSFLSAAIVGLIY
>ecocyc__NUPC-MONOMER nucleoside:H<sup>+</sup> symporter NupC (Escherichia coli K-12 substr. MG1655)
MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLAWFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFISALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGKISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVDASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTGWFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIASTLSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLSASIAALVL
>ENA__CAA52821.1 NupC (Escherichia coli)
MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLAWFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSNDQGLAEFFFLKVLCPIVFISALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGKISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVDASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTGWFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIASTLSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLSASIAALVL