>WP_048036790.1 NCBI__GCF_000007065.1:WP_048036790.1
MSKEELLQELADAVITCKKDAVLAAVEKAKGELDPSEIIENGLAAGMNEVGVRFERGKLFLPHVMMAADAMTAGVNALKDLMPEGSASSKMGVIVNGTVEGDVHDIGKSIVSTMLQSAGFEVHDIGRDVPIRNFIEKAKEVNADMIGLSALMTTTLPGQRDVIELLKEEGLRDKVKVMIGGAPATQAWADKIGADCYAENASEAVTKAKELLA
>metacyc__MONOMER-12211 dimethylamine corrinoid protein (Methanosarcina barkeri)
MSKEELLQELADAIISCKKDTVLAVVEKAKGELEPSEIIEKGLAAGMNEVGVRFERGKLFLPHVMMAADAMTAGVAALKDLMPEGASGSKLGVIVNGTVEGDVHDIGKAIVSTMLQSAGFEVHDIGRDVPIRNFIEKAKEVNADMIGISALMTTTLQGQKSVIELLKEEGLRDKVKVMVGGAPATQAWADKIGADCYAENATEAVAKAKELLA
>biolip__7xcnP Crystal structure of the mttb-mttc complex at 2.7 a resolution
ANKEEIIAKAKEAITDFDDELAEEVANEALAAGIDPVELIEKGFTAGMEEVGEKFGQGELFLPHVLAAAEAMNSGIKVITPEMEKRKSQTKSLGTVAIGTIEGDIHSIGKDIVASMLNIAGFKVVDLGRDVPINTFVEKVKELKPQVVASSALMTTTMVNQIQIEEQLKEAGVRDQVKTMVGGAPVTQDWADKIGADIYGESANDAVAKVKAALN
>metacyc__MONOMER-12207 trimethylamine-specific corrinoid protein (Methanosarcina barkeri)
MANKEEIIAKAKEAITDFDDELAEEVANEALAAGIDPVELIEKGFTAGMEEVGEKFGQGELFLPHVLAAAEAMNSGIKVITPEMEKRKSQTKSLGTVAIGTIEGDIHSIGKDIVASMLNIAGFKVVDLGRDVPINTFVEKVKELKPQVVASSALMTTTMVNQIQIEEQLKEAGVRDQVKTMVGGAPVTQDWADKIGADIYGESANDAVAKVKAALNV
>metacyc__MONOMER-21033 glycine betaine-specific corrinoid protein (Desulfitobacterium hafniense (strain Y51))
MIMSLLDELKQAIIDGDEDIVAELSQKAVDEDLDLVDTVQSGLVKGIEVVGTAWKEGEMFLPDVMMSAEAMKVGLAILEPEIAKKGMSEGESKGKIVLGTVEGDIHDIGKNITGAMFTAAGYKVIDLGTDIKAEGFVAKAQEVGADIIGASALLTTTMIKQKELIEYLKEKNLRDSYKVLVGGGPTSQVWADEIGADGWAETADDAVELANKILGK
>BRENDA__Q8THX4 tetrahydromethanopterin S-methyltransferase (EC 2.1.1.86) (Methanosarcina acetivorans)
MAKEDILNTLADAVVDGDDELAEEFAQKALDEELDAYEAIVDGLARGMKIISDMYERGEAFVPSLLLAADAMYAGMDILTPYMKVDGTAAPKNVIIGTVEGDVHDIGKNLVKTMMTAAGFNMIDLGCDVPLDKFAETAKEKKAAAISMSTLMTTTMGGMETVIEQLQEEGIRDSLIVMVGGAPISQTFADSVGADGTALDASAAVETLTSLVSELPSDSWSDSAIAASKMKYKEVLAQKSGKEKVDIGRITAEKIIAEFDSVVPKFNETMTKAERFGAAFQDKKVDRLPVAPLACGVSRKFVPCSYVDYSTKAEKYADCVEAGIKYFNMDTFVGLTDLCVDAADFGATIRYPEEDTPAATGHLEDYEKLEVPELKEGTRAYNLIQGNKLATEKAHALDAPMTALIEGPMVALTQIMGATRVLSDLRTNPDVVLKALDKTTVYVEEIMKGMFEEAQPDNLCMVNLWTNNVILSADEYMKSEGQVMQNRIAPLYKKYNKPVVIHNCADAPHWELINKWNTEYYSYTFYPDEAGKGSKDHKYLINNYGKETMFGGEVSPIVFLDNSPEGLQKMKADTIALQESVLNTLKENGMQSKYMISTGCEVPPGAPCDSITAQTYTVAEKGPELYKKIIG
>reanno__Phaeo_GFF1319 Methionine synthase component, B12 binding and B12-binding cap domains (EC:2.1.1.13) (Phaeobacter inhibens BS107)
MSEDADDIILADLNDEDLVQQMFDDLYDGLKEEIEESVNILLERGWAPYKVLTEALVGGMTIVGADFRDGILFVPEVLLAANAMKGGMAILKPLLAETGAPRMGSMVIGTVKGDIHDIGKNLVSMMMEGAGFEVVDIGINNPVENYLEALEEHQPDILGMSALLTTTMPYMKVVIDTMIEQGKRDDYIVLVGGAPLNEEFGKAIGADGYCRDAAVAVEMAKDFVARKHNQMSA
>reanno__Miya_8499710 vitamin B12-dependent methionine synthase without a reactivation domain (EC 2.1.1.13) (Desulfovibrio vulgaris Miyazaki F)
MPDFRQALRSGRRLVFDGGMGTMLQSRGLPPGVSPELFCLARPDVLVGIHADYLRAGADVLTTNTFGGCIHKLGTGPGAPDVVEFNRAMARAAREAVLASGREAFVAGSVGPSGHFMRPLGDLDPAELVAAFRAQIRGLVQGGVDLILAETQFDLAEARAIVLAARAECDLPVGVSMTFENGVSLTGTRPEVFVQSMLNMGVDLVGTNCSAGPEQMAEVADELLAISEVPVLVEPNAGLPELVDGKTVFRLGPDDFARHTARFAASGVRMLGGCCGTTPDHIAALRGALDNLSGGLVPDPARRDGIVLTTRAQAVHIGAGSPIRIIGERINPTGKKLLTAELQAGEFAQALRFADEQVEAGAPLLDVNVGAPMVDEAVLLPALVERLVARHSLPLSLDSSNADAIAAALPFHPGSPLVNSISGEPGRMEHLGPLCRDHGAPFILLPLKGRKLPVTAAERIAIIEELLQQADSLRIPRRLVMVDVLALAVSSKAEAARHCLDTIRWCAAQGLPTTIGLSNISFGLPARELLNSTFLAMAAGAGLSSCIAHPGNARIREAVAASSVLLGLDANAESFIEGYSGWTPGGDATGATPAGVAGGTGGGTGGVKAKAATLEEAVIRGDREGALALVERALSEGADPFSLVQEKLIPGITEVGRRYERREYFLPQLIRSAETMQHAFRKLQPLLEAQRGHEARPVIIMATVEGDIHDIGKNIVTLMLGNHGFDVVDLGKDVKAADIVEAAERHGARVIGLSALMTTTMVRMEDTVRLVRERGLPVKVMVGGAVVTPAYAEAIGADGYSADAVEAVRVAKELLTVQ
>reanno__DvH_207036 Methionine synthase (cobalamin-dependent) (EC 2.1.1.13) (Desulfovibrio vulgaris Hildenborough JW710)
MPDFRQALRAGRRLLFDGGLGTMLQARGLPAGVSPEQFCLDRPDVLRGIHADYVRAGADILTTNTFGGSRFKLGDGFDVVDFNRRMAAIAREAADASGRQAFVAGSIGPTGHFVKPLGEVEPAALVAAFREQVRGLVAGGADLLMIETQFDLAEARAAVVAARAECSLPIAVSMTFENGVSLTGSTPEVFVATMLNLGVDLLGTNCSAGPDQMHDVVASLLASASVPVLVEPNAGLPELIDGKTVFRLPPAPFAEKTAAFAAMGARVLGGCCGTTPDHIAALRQAVADIPATLPVDSGVGIVLTTRSHLVRVGGDAPVRIIGERINPTGKKQLIAELQAGDFSLALRFSDEQVEAGAPILDVNVGAPMVDEEVLLPDLVQRLITRHGVPLSIDSSNAAAIERALPYCPGSTLVNSISGEPGRMERLGPLCRDHGAPFILLPLKGRKLPVAATERIAIIEELLVQAEGLGIPRRLVMVDVLALAVSSKAEAARQCLETIRWCTANGFATTIGLSNISFGLPARELLNGTFLAMAAGAGLSSCIAHPGNGRIRETVACADVLLARDANAERFIDAYAAWTPATQGGPVASGPGLASQPPATTLEEAVVKGDRDGVTAIVESELAAGADPFDLVQTKLIPAINEVGVKYERREYFLPQLIRSAETMQTAFRRLQPLLEEMRGAEVRPVIIMATVEGDIHDIGKNIVSLMLGNHGFEVVDLGKDVKAETIVDAAETHGARIIGLSALMTTTMVRMEDTVKLVRARGLDVKVIVGGAVVTKAFADAIGADGYSADAVEAVRLAKSLLAG
>biolip__4jgiB 1.5 angstrom crystal structure of a novel cobalamin-binding protein from desulfitobacterium hafniense dcb-2
VIDLNASAQAMSDLDEGAINEVVDKVMAKADADAAQELIKAFQQGMTKVGERFDSGEYFIGDLIFAGEILQAAMDKLKPALEKRAKIVLATVEGDLHDIGKNIFRTMAEASGFEVFDLGIDVPVKIIVDKVKEVNPEIVGLSGVLTLALDSMRETVDALKAEGLRNDLKVIIGGVPVNENVCQRVGADDFSTNAADGVKICQRWVG
>BRENDA__Q9WYA5 methionine synthase (EC 2.1.1.13) (Thermotoga maritima)
MRNRREVSKLLSERVLLLDGAYGTEFMKYGYDDLPEELNIKAPDVVLKVHRSYIESGSDVILTNTFGATRMKLRKHGLEDKLDPIVRNAVRIARRAAGEKLVFGDIGPTGELPYPLGSTLFEEFYENFRETVEIMVEEGVDGIIFETFSDILELKAAVLAAREVSRDVFLIAHMTFDEKGRSLTGTDPANFAITFDELDIDALGINCSLGPEEILPIFQELSQYTDKFLVVEPNAGKPIVENGKTVYPLKPHDFAVHIDSYYELGVNIFGGCCGTTPEHVKLFRKVLGNRKPLQRKKKRIFAVSSPSKLVTFDHFVVIGERINPAGRKKLWAEMQKGNEEIVIKEAKTQVEKGAEVLDVNFGIESQIDVRYVEKIVQTLPYVSNVPLSLDIQNVDLTERALRAYPGRSLFNSAKVDEEELEMKINLLKKYGGTLIVLLMGKDVPKSFEERKEYFEKALKILERHDFSDRVIFDPGVLPLGAEGKPVEVLKTIEFISSKGFNTTVGLSNLSFGLPDRSYYNTAFLVLGISKGLSSAIMNPLDETLMKTLNATLVILEKKELPRAEVKEEKLVEIILSGNRSELEKLVEDFLKEKDPLSVIEEHLRPAMERIGELYDKGKIFLPQLILAAQTVKPVFDKLTSMLPSDSQGETFVIATVKGDVHDIGKNIVASVIRSSGYRVVDLGKDVDTSEIVEAVEKERPVALGLSAMMTTTVGRIKEVVEKLKEKNLKIPVIVGGASLNEKLAKELGADYYAKNASEAVKILKSLGR
>metacyc__MONOMER-12209 monomethylamine corrinoid protein (Methanosarcina barkeri)
MANQEIFDKLRDAIVNQNVAGTPELCKEALAAGVPALDIITKGLSVGMKIVGDKFEAAEIFLPQIMMSGKAMSNAMEVLTPELEKNKKEGEEAGLAITFVAEGDIHDIGHRLVTTMLGANGFQIVDLGVDVLNENVVEEAAKHKGEKVLLVGSALMTTSMLGQKDLMDRLNEEKLRDSVKCMFGGAPVSDKWIEEIGADATAENAAEAAKVALEVMK
>biolip__3ezxA Structure of methanosarcina barkeri monomethylamine corrinoid protein
ANQEIFDKLRDAIVNQNVAGTPELCKEALAAGVPALDIITKGLSVGMKIVGDKFEAAEIFLPQIMMSGKAMSNAMEVLTPELEKNKKEAGLAITFVAEGDIHDIGHRLVTTMLGANGFQIVDLGVDVLNENVVEEAAKHKGEKVLLVGSALMTTSMLGQKDLMDRLNEEKLRDSVKCMFGGAPVSDKWIEEIGADATAENAAEAAKVALEVM
>metacyc__MTACMBARK-MONOMER Co(I) methanol-specific corrinoid protein (Methanosarcina barkeri (strain Fusaro / DSM 804))
MLDFTEASLKKVLTRYNVALEKALTPEEAAEELYPKDELIYPIAKAIFEGEEDDVVEGLQAAIEAGKDPIDLIDDALMVGMGVVIRLYDEGVIFLPNVMMSADAMLEGIEYCKENSGATPKTKGTVVCHVAEGDVHDIGKNIVTALLRANGYNVVDLGRDVPAEEVLAAVQKEKPIMLTGTALMTTTMYAFKEVNDMLLENGIKIPFACGGGAVNQDFVSQFALGVYGEEAADAPKIADAIIAGTTDVTELREKFHKH
>SwissProt__P0DX07 Quaternary-amine-specific corrinoid protein; Corrinoid protein MtqC (Eubacterium limosum)
MADWKNLTQAVGDLEEDDVMEILNDFVATNPTEAEAEEAVAACQAGMAVVGDLFEEGEYFVGDLIFAGELLTEAINVLKPVLGSGDTAVAGTILIGTAHGDLHDIGKNIFRSMAEAAGFQVTDLGIDVAIDTFVEKAKEIKPDIIGISGVLTLAIDSMKETSDALKAAGVDSKLIIGGNPVTKEACEYVGADDFTTNAAEGVKICQAWVG
>PDB_1bmt_A How a protein binds b12: a 3.O angstrom x-ray structure of the b12- binding domains of methionine synthase
QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVA
YLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPS
LDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETV
RIQHGR
>biolip__3bulA E. Coli i690c/g743c meth c-terminal fragment (649-1227)
QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPCEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQCKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDAD
>ecocyc__HOMOCYSMETB12-MONOMER cobalamin-dependent methionine synthase (EC 2.1.1.13) (Escherichia coli K-12 substr. MG1655)
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAQAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPEIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDDTANAQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDAD
>PDB_3iva_A Structure of the b12-dependent methionine synthase (meth) c-teminal half with adohcy bound
QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPCEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVA
YLEPFIEASKEQCKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPS
LDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETV
RIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVG
VEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPK
LSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENY
QGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMS
VTEVERWLAPNLGYDA
>ENA__CAB39403.1 CmuA protein (Methylorubrum extorquens)
MAAQSGKMTSRERMFAAVTMTDLPDQVPCVPLLMARGIREGGITVDQALRDGEASAHAKAKALEKFGGDVIIAGTDLFTPVECVDGCELDYLPHAQPSLVRHPTPNREAFYRFKEKYEREGFKPSDRVLQIMKEAQTMIKLGYKDTHVIPTPVGGPITTAQLMTGSSEFLSYLSEDPEYALEVTELALDVVKNVCRLMFESGIDVCNILDPFNSSDILPPEVYRKHGLPFQKRLFAYIKEIGGIGFTHTCTFTQPIWRDIAENGCLNFNGDMYPGMEHAKRAIGGQISLMGTLSPFSTLMHGSTTDVANEVKKLAAEVGYNGGFICMPGCDIDWTIPDENLKAMIDTCASIKYPMDIAALGDLSNVYIAGNPKHPGKRSSSVAGDVKVEAGKKHELDTSPEGEVYEKLVEAIMDYDADKAKQWVQVGLDRGISAQKIVFDGLSLGMKIVGDMYERNERFVTDMLKAAKTMDAAMPLLTPLLESSGSDGGPTGTVIVGLVRGNTQDIGKNLVCLMLKANGFKVIDLGKNVKPEQFIETAEREGAVAIGMSVMTNSSTVYVEKVAEMLKSQGKADKYLLMMGGAAANRGVAEKFGVRYGLDANAAVSLVRDHVESRAAA
>metacyc__MONOMER-12242 methanethiol corrinoid protein (Methanosarcina barkeri)
MIRHIDLAVQNILEMKEKEPAKFKRLIDEGIMIGLGVDLEDGNKEVTTVDQIKNQNRPKDPEYASVAEAVIEGNNAETVKLISALLEKGKDPTDLVLNALMPGIQTVCELYDIGESYVPEILLANEALMKGVELCQKKKGEVPSQGKVVSLVIVGDLHDIGKNIVAAILRANGFEVIDLGRDVTVEAAVEAVKSTKANLVTGTTLMSTTKGGLKALANALEPEGVPLACGGAAVDRRFVDTFGNSVYGRTPLDAVKIAKEICEGKSWEEARNELY
>biolip__8g3hA Structure of cobalamin-dependent methionine synthase (meth) in a resting state
RRFPYLRALSQRVLVFDGAMGTELQKRDLTPEDYGEEAYYGCPEVLNRTRPDVVREIHLSYLEAGAEVIETNSFGALRHVLAEYGLGEEAEELAYRAARIAKEAAEPYGAFVAGALGPGTKLVSLGQISWEELFSAYKEAVRGLVRGGVDLILLETAQDILQVRCAVLAAREAMAELGVELPLQVQVTFEATGTMLVGTDEQAALAALESLPIDVVGMNCATGPDLMDAKIRYFAQESTRFVACLPNAGLPRNEGGRVVYDLTPEELARWHLKFVTEYGVNAVGGCCGTGPEHIRKVAEAVGGRPSPVHKTAFPPQVASLYQAVPLRQETSLLLVGERLNATGSKRFRELLFAGDLEGILALAQEQVAEGAHVLDLSVAWTGRDELEDMKRVLSKLATGVTVPFMVDSTSPEVMEEALKRLPGRAILNSANLEDGLEKFDRVASLAKAHGAALVALAIDEEGMAKTRVKKVEVALRMYERLTEHHGLRPEDLLFDLLTFPITQGDEETRPLARETLLALEELRERLPGVGFVLGVSNVSFGLKPKARRVLNSVFLDEARKKGLTAAIVDAGKILPISQIPEEAYALALDLIYDRREGQDPLFAFIRFFEEHKEVLAEDKEAFQALPVEERLRRRVLEGKRVGLEEDLAEALGRMRPLEIINGPLLEAMKEVGELFGAGKMQLPFVLQAAEVMKQAVAYLEPHMEKKGEGKGKLVLATVKGDVHDIGKNLVDIILTNNGYTVYNLGIKVPIEEMLKAVDEVKPHALGMSGLLVKSTQVMKENLEYMRARGYTLPVILGGAALTRAYVEELRSIYPEVYYAEDAFEGLALMEELTGHRPKDLT
>metacyc__G18NG-11090-MONOMER cobalamin-dependent methionine synthase (EC 2.1.1.13) (Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025))
MSTSVTSPAHNNAHSSEFLDALANHVLIGDGAMGTQLQGFDLDVEKDFLDLEGCNEILNDTRPDVLRQIHRAYFEAGADLVETNTFGCNLPNLADYDIADRCRELAYKGTAVAREVADEMGPGRNGMRRFVVGSLGPGTKLPSLGHAPYADLRGHYKEAALGIIDGGGDAFLIETAQDLLQVKAAVHGVQDAMAELDTFLPIICHVTVETTGTMLMGSEIGAALTALQPLGIDMIGLNCATGPDEMSEHLRYLSKHADIPVSVMPNAGLPVLGKNGAEYPLEAEDLAQALAGFVSEYGLSMVGGCCGTTPEHIRAVRDAVVGVPEQETSTLTKIPAGPVEQASREVEKEDSVASLYTSVPLSQETGISMIGERTNSNGSKAFREAMLSGDWEKCVDIAKQQTRDGAHMLDLCVDYVGRDGTADMATLAALLATSSTLPIMIDSTEPEVIRTGLEHLGGRSIVNSVNFEDGDGPESRYQRIMKLVKQHGAAVVALTIDEEGQARTAEHKVRIAKRLIDDITGSYGLDIKDIVVDCLTFPISTGQEETRRDGIETIEAIRELKKLYPEIHTTLGLSNISFGLNPAARQVLNSVFLNECIEAGLDSAIAHSSKILPMNRIDDRQREVALDMVYDRRTEDYDPLQEFMQLFEGVSAADAKDARAEQLAAMPLFERLAQRIIDGDKNGLEDDLEAGMKEKSPIAIINEDLLNGMKTVGELFGSGQMQLPFVLQSAETMKTAVAYLEPFMEEEAEATGSAQAEGKGKIVVATVKGDVHDIGKNLVDIILSNNGYDVVNLGIKQPLSAMLEAAEEHKADVIGMSGLLVKSTVVMKENLEEMNNAGASNYPVILGGAALTRTYVENDLNEVYTGEVYYARDAFEGLRLMDEVMAEKRGEGLDPNSPEAIEQAKKKAERKARNERSRKIAAERKANAAPVIVPERSDVSTDTPTAAPPFWGTRIVKGLPLAEFLGNLDERALFMGQWGLKSTRGNEGPSYEDLVETEGRPRLRYWLDRLKSEGILDHVALVYGYFPAVAEGDDVVILESPDPHAAERMRFSFPRQQRGRFLCIADFIRPREQAVKDGQVDVMPFQLVTMGNPIADFANELFAANEYREYLEVHGIGVQLTEALAEYWHSRVRSELKLNDGGSVADFDPEDKTKFFDLDYRGARFSFGYGSCPDLEDRAKLVELLEPGRIGVELSEELQLHPEQSTDAFVLYHPEAKYFNV
>biolip__8sseA Methionine synthase, c-terminal fragment, cobalamin and reactivation domains from thermus thermophilus hb8
PLLERLKRRVVEGRKQGLEADLEEALKAGHKPLDLINGPLLAGMKEVGDLFGAGKMQLPFVLQAAEVMKRAVAYLEPHMEKEGKGTLVLATVKGDVHDIGKNLVDIILSNNGYRVVNLGIKVPIEEILKAVEAHKPHAVGMSGLLVKSTLVMKENLEYMRDRGYTLPVILGGAALTRSYVEELRAIYPNVYYAEDAFEGLRLMEELTGHAPPELTRPRARPVGEAPAVPRPPFFGVRVEEGLDLATIAHYVNKLALYRGQWGYSRKGLSREAWQALVEREAEPVFQRLLKEAMAEGWLEPKVLYGFFPVAREGEELLVFSPETGEVLERFRFPRQKGGGLSLVDYFRPRFAAPLGDEADWMPKEAFRAGARDVLGVQLVTMGEAPSRKAQALFASGAYQDYLFVHGFSVEMTEALAEYWHKRMRQMWGIAHQDATEIQKLFQQGYQGARYSFGYPACPDLADQAKLDRLMGFHRVGVRLTENFQLEPEHATSALVVHHPEARYFSVD
>SwissProt__Q9Z2Q4 Methionine synthase; MS; 5-methyltetrahydrofolate--homocysteine methyltransferase; Cobalamin-dependent methionine synthase; Vitamin-B12 dependent methionine synthase; EC 2.1.1.13 (Rattus norvegicus (Rat))
MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEENFQGQEFKDHSRPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGSLGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQKLFEENYASPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDPLCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPAMMAMHLKDFAVDGLVNVVGGCCGSTPDHIREIAEAVKNCKPRVPPDSVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSKKFAKLIMAGNYEEALSVAKVQVEMGAQVLDINMDDGMLDGPSAMTKFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEEDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVSVCTRAYHLLVEKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFAFRGMDAIREAMHGVFLYHAIKFGMDMGIVNAGSLPVYDDIHKDLLQLCEDLIWNRDAEATEKLLRYAQTHGKGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNREKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARVLNGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDDYFEEILEEYEDIRQDHYESLKERKYLPLSQARKHSFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYEDAQNMLSILISRKKLRARGVVGFWPAQSVQDDIHLYAEGAVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFVAPLHSGVRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLGVTDLRKLRYEGIRPAPGYPSQPDHTEKLTMWRLANIEQATGIRLTESLAMAPASAVSGLYFSNVKSKYFAVGKISKDQIEDYALRKNMSVAEVEKWLGPILGYDTD
>metacyc__HS04076-MONOMER cobalamin-dependent methionine synthase (EC 2.1.1.13) (Homo sapiens)
MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQATETDTKIRVCTRAYHLLVKKLGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATKVIKETLPGARISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKSGMDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTQGTGGKKVIQTDEWRNGPVEERLEYALVKGIEKHIIEDTEEARLNQKKYPRPLNIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREETRVLNGTVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDEYFEEIMEEYEDIRQDHYESLKERRYLPLSQARKSGFQMDWLSEPHPVKPTFIGTQVFEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKTVGGEARKVYDDAHNMLNTLISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAEKDSASTEPYYCLSDFIAPLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTGIRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALRKNISVAEVEKWLGPILGYDTD