>WP_013009416.1 NCBI__GCF_000025725.1:WP_013009416.1
MEILIINGPNLNMLGKREKSIYGEMTLNSINEMLLARAGGRCELEFFQSNHEGDIVGMIQRTDADGMIINAGAFTHTSIAIRDALLAVSKEFIEVHISNVFAREDFRHKSYLSDISKGVISGFGAMSYAFALDYFLEQKK
>BRENDA__A3M692 3-dehydroquinate dehydratase (EC 4.2.1.10) (Acinetobacter baumannii)
MSSTILVIHGPNLNLLGKREPEVYGHLTLDNINRQLIAQAEQASITLDTFQSNWEGAIVDRIHQAQTEGVKLIIINPAALTHTSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAIGVICGLGAKGYSFALDYAIEKIQPSNPN
>biolip__5b6pB Structure of the dodecameric type-ii dehydrogenate dehydratase from acinetobacter baumannii at 2.00 a resolution
STILVIHGPNLNLLGKREPEVYGHLTLDNINRQLIAQAEQASITLDTFQSNWEGAIVDRIHQAQTEGVKLIIINPAALTHTSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAIGVICGLGAKGYSFALDYAIEKIQP
>SwissProt__P43877 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 (Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae))
MKKILLLNGPNLNMLGKREPHIYGSQTLSDIEQHLQQSAQAQGYELDYFQANGEESLINRIHQAFQNTDFIIINPGAFTHTSVAIRDALLAVSIPFIEVHLSNVHAREPFRHHSYLSDVAKGVICGLGAKGYDYALDFAISELQKIQLGEMMNG
>PDB_5ydb_A Crystal structure of the complex of type ii dehydroquinate dehydratase from acinetobacter baumannii with dehydroquinic acid at 1.76 angstrom resolution
STILVIHGPNLNLLGKREPEVYGHLTLDNINRQLIAQAEQASITLDTFQSNWEGAIVDRIHQAQTEGVKLIIINPAALTH
TSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAIGVICGLGAKGYSFALDYAIEKIQP
>BRENDA__A5WDH9 3-dehydroquinate dehydratase (EC 4.2.1.10) (Psychrobacter sp. PRwf-1)
MSHSPSTAASPKLFQHRRILLINGPNLNLLGLREPHIYGHTTLQDIEQRLTATAHAQNIELISIQSNHEGELVDAVQHHGILADAEDLIDAVIINPAAFTHTSVALRDALLGVNKPFIEVHLSNIHSREPFRSHSYFSDKAVGVICGLGHLGYDMALSYLLQQDEDK
>SwissProt__P05147 Catabolic 3-dehydroquinase; cDHQase; 3-dehydroquinate dehydratase; EC 4.2.1.10 (Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans))
MEKSILLINGPNLNLLGTREPHIYGSTTLSDVEESSKGHAASLGASLQTFQSNHEGAIVDRIHAARGNTDAIIINPGAYTHTSVAIRDALLGVEIPFIELHVSNVHAREPFRHHSYFSDKASGIIVGLGVYGYKVAVEHVALNFKPLEKKAAL
>BRENDA__Q0VMZ2 3-dehydroquinate dehydratase (EC 4.2.1.10) (Alcanivorax borkumensis)
MITANNDKFARGPILASILVLHGPNLNLLGTREPDKYGHTTLADINQQLQEQASKAGHHLQHLQSNAEYELVECIHDAHTEGVDFIIINPAAFTHTSVALRDALLAVNIPFIEVHLSNVHARETFRHHSFFSDIAKGVICGLGAIGYALALTAALEQLDD
>BRENDA__M1E6S9 3-dehydroquinate dehydratase (EC 4.2.1.10) (Thermodesulfobium narugense)
MKKILVINGPNLNMLGTREPNIYGSITLHGLEELILNFAKELEMKVDFFQSNHEGDIIDKIHRTFDAYDAFIINPGAFTHYSYAIRDAIASITIPVIEVHLSNVHAREEFRKSSVIAPVCLGQISGLGELSYIAAIVALDKYLQKLEKRA
>BRENDA__A8AQF2 3-dehydroquinate dehydratase (EC 4.2.1.10) (Citrobacter koseri)
MADKLHILLLNGPNLNMLGTREPDKYGTLTLTEIVNRLNAEADALNVTLDHLQSNAEYALIDRIHQAKDTVDYILINPAAFTHTSVAIRDALLAVSIPFIEIHLSNVHAREPFRQHSYLSDIAAGVICGFGADGYSYALQTAVKRLSQSH
>BRENDA__A0A0H3FM50 3-dehydroquinate dehydratase (EC 4.2.1.10) (Klebsiella aerogenes)
MADKFRILLLNGPNLNMLGSREPEKYGSLTLAEIVNRLTAEAEALNVTLDHLQSNAEFALIDRIHQAKDSVDYILINPAAFTHTSVAIRDALLAVSIPFIEIHLSNVHAREPFRHHSYLSDVASGVICGLGADGYSYALQTAVKRLSQTH
>BRENDA__A1SZA3 3-dehydroquinate dehydratase (EC 4.2.1.10) (Psychromonas ingrahamii)
MTQQIKLLVLNGPNLNLLGQREPEVYGSKTLDDIIKALTDEAALQNVALSHLQSNREYELIEKIHDAFEKIDFIIINPAAFTHTSVALRDALLGVNIPFIEVHLSNVHARESFRHHSYLSDIAQGVICGLGAKGYSFALQSAIGKLRNI
>BRENDA__G8M0G7 3-dehydroquinate dehydratase (EC 4.2.1.10) (Acetivibrio clariflavus)
MKKILIINGPNLNLLGTREKEVYGTETLDDIAKKVAEEAAKLNVNIEFFQSNHEGDIIDKIHAARGNTDAIIINPGAYTHYSIAIRDAIKAVEIPTIEIHLSNIHAREEFRSHSVIAPVCVGQICGFGSNSYILGLNAAALL
>BRENDA__O30557 3-dehydroquinate dehydratase (EC 4.2.1.10) (Pseudomonas aeruginosa)
MATLLVLHGPNLNLLGTREPGTYGSTTLGQINQDLERRAREAGHHLLHLQSNAEYELIDRIHAARDEGVDFIIINPAAFTHTSVALRDALLAVSIPFIEVHLSNVHKREPFRHHSYFSDVAVGVICGLGATGYRLALESALEQLQRP
>BRENDA__D4LCT8 3-dehydroquinate dehydratase (EC 4.2.1.10) (Ruminococcus champanellensis)
MRILVIHGPNLNLLGEREPGIYGKNDLAHVNGAILTRAKELGVECEVFQSNHEGEILVRLHEARHAFDGVVLNAGAYTHYSYAIRDAIAAIRIPCVEVHISNVHAREEFRHTSVIAPACLGVVCGFGGDSYLLALEGLVRHCAGQKTL
>SwissProt__Q48255 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 (Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori))
MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAFSHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEAQKNNPNNPINNQK
>PDB_4b6r_A Structure of helicobacter pylori type ii dehydroquinase inhibited by (2s)-2-(4-methoxy)benzyl-3-dehydroquinic acid
MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAF
SHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEAQKN
>PDB_2xd9_A Structure of helicobacter pylori type ii dehydroquinase in complex with inhibitor compound (4r,6r,7s)-4,6,7-trihydroxy-2-((e)-prop-1- enyl)-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid
MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAF
SHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQE
>PDB_2wks_A Structure of helicobacter pylori type ii dehydroquinase with a new carbasugar-thiophene inhibitor.
MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAF
SHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQE
>PDB_2xda_A Structure of helicobacter pylori type ii dehydroquinase in complex with inhibitor compound (4r,6r,7s)-2-(2-cyclopropyl)ethyl-4,6,7- trihydroxy-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid
MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAF
SHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKA
>PDB_4b6s_A Structure of helicobacter pylori type ii dehydroquinase inhibited by (2s)-2-perfluorobenzyl-3-dehydroquinic acid
MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAF
SHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEAQKNN
>PDB_2xb9_A Structure of helicobacter pylori type ii dehydroquinase in complex with inhibitor compound (2r)-2-(4-methoxybenzyl)-3-dehydroquinic acid
MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAF
SHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEAQKNN
>PDB_1j2y_A Crystal structure of the type ii 3-dehydroquinase
MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAF
SHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEAQKNN
>biolip__2c4wA Type ii dehydroquinase from h. Pylori in complex with ah9095
AGLVPRGSHMKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSEYEGIIINPGAFSHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEAQKNNP
>SwissProt__P54517 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 (Bacillus subtilis (strain 168))
MPHFLILNGPNVNRLGSREPEVFGRQTLTDIETDLFQFAEALHIQLTFFQSNHEGDLIDAIHEAEEQYSGIVLNPGALSHYSYAIRDAVSSISLPVVEVHLSNLYAREEFRHQSVIAPVAKGQIVGLGAEGYKLAVRYLLSQQGGESR
>SwissProt__Q59Z17 Catabolic 3-dehydroquinase; cDHQase; 3-dehydroquinate dehydratase; EC 4.2.1.10 (Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast))
MVKKVLLINGPNLNLLGTREPEKYGTTSLSDIEQAAIEQAKLKNNDSEVLVFQSNTEGFIIDRIHEAKRQGVGFVVINAGAYTHTSVGIRDALLGTAIPFIEVHITNVHQREPFRHQSYLSDKAVAVICGLGVYGYTAAIEYALNY
>SwissProt__P05195 Catabolic 3-dehydroquinase; cDHQase; 3-dehydroquinate dehydratase; Quinic acid degradation cluster protein 2f; EC 4.2.1.10 (Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987))
MASPRHILLINGPNLNLLGTREPQIYGSTTLHDIEQASQTLASSLGLRLTTFQSNHEGAIIDRIHQAAGFVPSPPSPSPSSAATTTEAGLGPGDKVSAIIINPGAYTHTSIGIRDALLGTGIPFVEVHVSNVHAREAFRHHSYLSDKAVAVICGLGPFGYSAALDFLGRHMKF
>BRENDA__N1V364 3-dehydroquinate dehydratase (EC 4.2.1.10) (Arthrobacter crystallopoietes)
MGNMSEHSTGSSTRKLLVLNGPNLNLLGTREPQIYGSDTLEDAETLAARAAEAHGLAVECLQSNHEGVLIDAIHAARGTAAGIVINPGGYTHTSVALRDALSGVDLPVVEVHISNIHRREEFRHHSYISGIAVAVIAGAGISGYKFAVDLLASRL
>metacyc__MONOMER-15328 periplasmic dehydroquinate dehydratase (EC 4.2.1.10) (Gluconobacter oxydans (strain 621H))
MTAPKVLSRGQMKRPLITVLNGPNLNMLGLRQPGIYGHATLDDVEQVCIQAAERLDVAIDFRQTNGEGELVSWVQECRGRADGIVINPAAYGHTSIALLDALLAVELPVIEVHISNIHRREPFRHHTYVSQAAIGVICGLGVRGYAHALQAITDMIEDEG
>BRENDA__W6JLW3 3-dehydroquinate dehydratase (EC 4.2.1.10) (Gluconobacter oxydans)
MTAPKVLSRGQMKRPLITVLNGPNLNMLGLRQPGIYGHATLDDVEQVCIQAAERLDVAIDFRQTNGEGELVSWVQECRGRADGIVINPAAYGHTSIALLDALLAVELPVVEVHISNIHRREPFRHHTYVSQAAIGVICGLGVRGYAHALQAITDMIEDEG
>BRENDA__Q9PH97 3-dehydroquinate dehydratase (EC 4.2.1.10) (Xylella fastidiosa)
MAHLLLLHGPNLNLLGTREPEIYGRITLPQIDAALAERATAAGHGLSSLQSNAEHVLIERIHATPEDGTAFILINPGAFTHTSVALRDALLAVALPFVEIHLSNPYTREPFRHHSYLADKALGVVCGFGVDSYRIALEGVIARLGSDV
>BRENDA__E4RLB7 3-dehydroquinate dehydratase (EC 4.2.1.10) (Halanaerobium hydrogeniformans)
MQKVAVIHGPNLNMLGLREPEIYGKNNLEMVNKNLKRKAKELDFEIEIMQSNHEGEIVDYLHQNFEQLDGVIINPGGLTHTSVILRDALAAVRLPVIEVHISNIHKREEFRHKSLTAAVAVGQITGLGVKGYTLALEGLKSILGREKY
>biolip__8idrC Crystal structure of apo-form of dehydroquinate dehydratase from corynebacterium glutamicum
PGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELIDALHNARGTHIGCVINPGGLTHTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLAAVSVIAGAGIQGYRFAVDILANLKKLEH
>BRENDA__O52377 3-dehydroquinate dehydratase (EC 4.2.1.10) (Corynebacterium glutamicum)
MPGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELIDALHNARGTHIGCVINPGGLTHTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLAAVSVIAGAGIQGYRFAVDILANLKK
>metacyc__MONOMER-15335 3-dehydroquinate dehydratase (EC 4.2.1.10) (Corynebacterium glutamicum (strain R))
MLGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELIDALHNARGTHIGCVINPGGLTHTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLAAVSVIAGAGIQGYRFAVDILANLKK
>biolip__6hs9A The crystal structure of type ii dehydroquinase from butyrivibrio crossotus dsm 2876
GSHMKILVINGPNLNFLGIREKNIYGNENYEYLVNMINEYCKSKNIEVECYQSNHEGAIIDKIQEAYFNGTDGIVINPGAYTHYSYAIRDALASVSHIKKIEVHISNVNEREEFRHISVTEPVCNGQIVGQGLKGYIMAIDMLNS
>BRENDA__D4S0D1 3-dehydroquinate dehydratase (EC 4.2.1.10) (Butyrivibrio crossotus)
MKILVINGPNLNFLGIREKNIYGNENYEYLVNMINEYCKSKNIEVECYQSNHEGAIIDKIQEAYFNGTDGIVINPGAYTHYSYAIRDALASVSHIKKIEVHISNVNEREEFRHISVTEPVCNGQIVGQGLKGYIMAIDMLNS
>PDB_8idu_A Crystal structure of substrate bound-form dehydroquinate dehydratase from corynebacterium glutamicum
PGKILLLNGPNLNMLGKAEPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELIDALHNARGTHIGCVINPGGLTH
TSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLAAVSVIAGAGIQGYRFAVDILANLKKL
>PDB_6hsa_A The crystal structure of type ii dehydroquinase from butyrivibrio crossotus dsm 2876
GSHMKILVINGPNLNFLGIREKNIYGNENYEYLVNMINEYCKSKNIEVECYQSNHEGAIIDKIQEAYFNGTDGIVINPGA
YTHYSYAIRDALASVSHIKKIEVHISNVNEREEFRHISVTEPVCNGQIVGQGLKGYIMAIDMLNS
>PDB_2c57_A H.Pylori type ii dehydroquinase in complex with fa1
GSSHHHHHHSSSHMKILVIQGPNLNMLGGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGII
INPGAFSHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEA
QKNN
>BRENDA__A0A124C1Y7 3-dehydroquinate dehydratase (EC 4.2.1.10) (Streptomyces acidiscabies)
MPRTLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAATHGGTVDFRQSNHEGELVDWIHEARMDHCGIVINPGAYSHTSVAILDALNTCDGLPVIEVHISNIHKREAFRHHSYVSLRADGVIAGCGVQGYVFGVERVAALAGEGTARA
>BRENDA__B2A551 3-dehydroquinate dehydratase (EC 4.2.1.10) (Natranaerobius thermophilus)
MKIYVIHGPNINMLGNRESEHYGTQTLEELNSSIIKESESLGIEVEIFQFNSEGDIITKLQEANNYAQGVIINPGAYTHYSIAIRDAIAAISKPVIEVHISNIFNRESFRSHSVIAPVAKGQISGMGFAGYLLALNAFIKTKEG
>biolip__1v1jA Crystal structure of type ii dehydroquintae dehydratase from streptomyces coelicolor in complex with 3-fluoro
PRSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG
>SwissProt__P15474 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 (Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
MPRSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAGAGSARA
>PDB_2cjf_A Type ii dehydroquinase inhibitor complex
RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPA
AYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG
>PDB_2bt4_A Type ii dehydroquinase inhibitor complex
RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPA
AYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG
>PDB_1gu1_A Crystal structure of type ii dehydroquinase from streptomyces coelicolor complexed with 2,3-anhydro-quinic acid
RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPA
AYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG
>PDB_1gtz_A Structure of streptomyces coelicolor type ii dehydroquinase r23a mutant in complex with dehydroshikimate
RSLANAPIMILNGPNLNLLGQAQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPA
AYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG
>SwissProt__P9WPX7 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
MSELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHVGT
>biolip__3n8kM Type ii dehydroquinase from mycobacterium tuberculosis complexed with citrazinic acid
LYFQSHMSELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHV
>PDB_4kiw_A Design and structural analysis of aromatic inhibitors of type ii dehydroquinate dehydratase from mycobacterium tuberculosis - compound 49e [5-[(3-nitrobenzyl)amino]benzene-1,3-dicarboxylic acid]
LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHT
SVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_4kiu_A Design and structural analysis of aromatic inhibitors of type ii dehydroquinate dehydratase from mycobacterium tuberculosis - compound 49d [5-[(3-nitrobenzyl)oxy]benzene-1,3-dicarboxylic acid]
LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHT
SVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_4ciw_A Crystal structure of mycobacterium tuberculosis type 2 dehydroquinase in complex with (1r,4r,5r)-1,4,5-trihydroxy-3-(2-hydroxy) ethylcyclohex-2-ene-1-carboxylic acid
LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHT
SVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_3n87_A Crystal structure of 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with inhibitor 3
LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHT
SVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_3n86_A Crystal structure of 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with inhibitor 4
LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHT
SVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_2xb8_A Structure of mycobacterium tuberculosis type ii dehydroquinase in complex with inhibitor compound (2r)-2-(4-methoxybenzyl)-3- dehydroquinic acid
LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHT
SVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_4b6o_A Structure of mycobacterium tuberculosis type ii dehydroquinase inhibited by (2s)-2-(4-methoxy)benzyl-3-dehydroquinic acid
ELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTH
TSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_3n59_C Type ii dehydroquinase from mycobacterium tuberculosis complexed with 3-dehydroshikimate
ELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTH
TSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_4b6p_A Structure of mycobacterium tuberculosis type ii dehydroquinase inhibited by (2s)-2-perfluorobenzyl-3-dehydroquinic acid
LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHT
SVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHV
>PDB_3n76_A Crystal structure of 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with compound 5
ELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTH
TSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHV
>PDB_4cl0_A Structure of the mycobacterium tuberculosis type ii dehydroquinase inhibited by a 3-dehydroquinic acid derivative
LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHT
SVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAE
>PDB_4kij_A Design and structural analysis of aromatic inhibitors of type ii dehydroquinase dehydratase from mycobacterium tuberculosis - compound 35c [3,4-dihydroxy-5-(3-nitrophenoxy)benzoic acid]
ELIVNVINGPNLGRLARREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTH
TSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>metacyc__MONOMER-20727 5-deoxy-5-amino-3-dehydroquinate dehydratase (Amycolatopsis mediterranei)
MVQAPCRTRCVPLPDVLLLNGPNLGVLGRREPEIYGTDTLADIEKAVAEEVRPRGWTVVPVQRDGEGELVGAIHQHRDTTVGAIVNPGALMIAGWSLRDALASYEPPWIEVHLSNVWAREQFRHDSVIAPLASGVVVGLGAFGYRLAAQALLHLSAESPNGLR
>BRENDA__B9CK59 3-dehydroquinate dehydratase (EC 4.2.1.10) (Lancefieldella rimae)
MDSQQAAQNVLLAIGGSDNLVSNEVCMTRLRLTVTDPTRIDTEQLGNLQGVLGIVGRGINGIEVVFGPNIAQQVNAAITACCNHTQASQVIPIPEDGSTSDEKEVEQLISLLRDVDLSVDNLSHTGTFDTDPKEESVTPEELTQDEQGLRLLIINGPNINMLGIREPKLYGKQDYRTLIKICKEEADRQGFIDCVCYQSNYEGDLVSAIQDALGTYDAILINPAAYTHTSIALLDAALSVKIPMVEVHLTDINEREEYRRVSYLKDACIGVCCGKGFESYREGIALLAKYLTEA
>PDB_4civ_A Crystal structure of mycobacterium tuberculosis type 2 dehydroquinase in complex with (1r,4r,5r)-1,4,5-trihydroxy-3-hydroxymethylcyclohex- 2-ene-1-carboxylic acid
LIVNVINGPNLGRLGRRGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALR
DACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHV
>BRENDA__D1A7X0 3-dehydroquinate dehydratase (EC 4.2.1.10) (Thermomonospora curvata)
MRHVLVLNGPNLRRLGTREPDVYGVQTFADLEALCRETGRRLSLHVDVRQTDDEAEMIRWVHEAADSRLPIVINPAAFTHYSYALRDALAQRTAPLVEVHISNPAAREEFRHNSVVAGVADGTIAGFGLYSYVLALQAVAEMLAREEAR
>BRENDA__Q88IJ6 3-dehydroquinate dehydratase (EC 4.2.1.10) (Pseudomonas putida)
MVANVLMLHGINHNMFGKRDPRQYGTATLADIDQALQALGEELGAQVESFQSNFEGAMCERIHQAYEDRVDAVLINAGAWTHYSYGIRDALAIIEVPVVEVHMSNIHAREPFRHHSVFAEVVRGQICGFGVETYLLALRAAMSMV
>PDB_3n8n_A Crystal structure of 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with inhibitor 6
LIVNVINGPNLGRLGRREPGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVAL
RDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_2y71_A Structure of mycobacterium tuberculosis type ii dehydroquinase complexed with (1r,4s,5r)-1,4,5-trihydroxy-3-((5-methylbenzo(b) thiophen-2-yl)methoxy)cyclohex-2-enecarboxylate
LIVNVINGPNLGRLGPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVA
LRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_1h0r_A Type ii dehydroquinase from mycobacterium tuberculosis complexed with 2,3-anhydro-quinic acid
ELIVNVINGPNLGRLGRVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVA
LRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHV
>PDB_4ciy_A Crystal structure of mycobacterium tuberculosis type 2 dehydroquinase in complex with (1r,4r,5r)-1,4,5-trihydroxy-3-((1r)-1-hydroxy-2- phenyl)ethylcyclohex-2-en-1-carboxylic acid
LIVNVINGPNLGRLGRYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALR
DACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_1h0s_A 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with 3-hydroxyimino-quinic acid
ELIVNVINGPNLGRLGRRGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALR
DACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHV
>PDB_2y76_A Structure of mycobacterium tuberculosis type ii dehydroquinase complexed with (1r,4s,5r)-3-(benzo(b)thiophen-5-ylmethoxy)-2- (benzo(b) thiophen-5-ylmethyl)-1,4,5-trihydroxycyclohex-2- enecarboxylate
ELIVNVINGPNLGRLGRGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALR
DACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>BRENDA__I0L192 3-dehydroquinate dehydratase (EC 4.2.1.10) (Micromonospora lupini)
MKVYVLNGPNLGRLGTREPAVYGSTSYADLVTLCEATGRELGLDVTVRQTDAEHELLGWLHAAADEGAAVVLNPAAWSHYSYAVRDACAMLRGPLVEVHLSNIHAREEFRHHSVVSAVATGVICGLGIDGYRLALHHLAARPA
>PDB_4b6q_A Structure of mycobacterium tuberculosis type ii dehydroquinase inhibited by (2r)-2-(benzothiophen-5-yl)methyl-3-dehydroquinic acid
LIVNVINGPNLGRLGRGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDA
CAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHV
>PDB_4cky_A Structure of the mycobacterium tuberculosis type ii dehydroquinase inhibited by a 3-dehydroquinic acid derivative
LIVNVINGPNLGRLGRGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDA
CAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_2y77_A Structure of mycobacterium tuberculosis type ii dehydroquinase complexed with (1r,4s,5r)-3-(benzo(b)thiophen-2-ylmethoxy)-1,4,5- trihydroxy-2-(thiophen-2-ylmethyl)cyclohex-2-enecarboxylate
LIVNVINGPNLGRLGRGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDA
CAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_4cix_A Crystal structure of mycobacterium tuberculosis type 2 dehydroquinase in complex with(1r,4r,5r)-1,4,5-trihydroxy-3-((1s)-1-hydroxy-2- phenyl) ethylcyclohex-2-en-1-carboxylic acid
LIVNVINGPNLGRLGRGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDA
CAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAE
>PDB_4ki7_A Design and structural analysis of aromatic inhibitors of type ii dehydroquinase from mycobacterium tuberculosis - compound 41c [3- hydroxy-5-(3-nitrophenoxy)benzoic acid]
LIVNVINGPNLGRLGGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDA
CAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH
>PDB_4v0s_A Crystal structure of mycobacterium tuberculosis type ii dehydroquinase d88n mutant inhibited by a 3-dehydroquinic acid derivative
SELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLT
HTSVALRNACAELSAPLIEVHISNVHAHSYLSPIATGVIVGLGIQGYLLALRYLAEHVGT