>WP_010966437.1 NCBI__GCF_000008765.1:WP_010966437.1
MILDDIVRDKKLQLIEDKKALSLDDIKSKLNSLNLDKRNFKEALEKENISIIAEIKKASPSKGVIREDFNPVKIGQIYENINIDAVSILTEKKYFLGKNEYIKIVKEVNSKPILRKDFIVDEYQLYEAKLIGADAVLLIAAVLKDKLECFYNRTLELGLDSITEVHNEEEAKLASEIGCSIIGINNRDLRDFSTDITTTKRLMKYVPRDRIIVSESSIKTPEDILYLRSIGVNAVLIGETFMRNIDDLKGINEFLKKAKDNG
>ecocyc__PRAI-IGPS fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (EC 4.1.1.48; EC 5.3.1.24) (Escherichia coli K-12 substr. MG1655)
MMQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDALQGARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFNFLPIVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGVLTEVSNEEEQERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGINTYAQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAGAIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQLHGNEEQLYIDTLREALPAHVAIWKALSVGETLPAREFQHVDKYVLDNGQGGSGQRFDWSLLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLRAY
>biolip__1piiA Three-dimensional structure of the bifunctional enzyme phosphoribosylanthranilate isomerase: indoleglycerolphosphate synthase from escherichia coli refined at 2.0 angstroms resolution
MQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDALQGARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFNFLPIVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGVLTEVSNEEEQERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGINTYAQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAGAIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQLHGNEEQLYIDTLREALPAHVAIWKALSVGETLPAREFQHVDKYVLDNGQGGSGQRFDWSLLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLRAY
>SwissProt__P49572 Indole-3-glycerol phosphate synthase, chloroplastic; IGPS; EC 4.1.1.48 (Arabidopsis thaliana (Mouse-ear cress))
MEGLVPVQRLPIKVASPSLYRCNNSVSIRRSISGFAMDRKINFRAPSQFSIRAQQSDLKESLAVSSSSVEDKGNVLRIKEWEVEMYQEELAISQGIRIRRKPPSKAPLGYSGPFELRLHNNDADSPRNILEEITWYKDVEVSRMKELNPLDVLKKAVEDAPPTRDFVGALRMAHKRTGFPGLIAEVKKASPSRGILKENFDPVEIAQAYEKGGAACLSVLTDQKYFQGGFENLEAIRSAGVKCPLLCKEFVVDPWQIYYARTKGADAVLLIAAVLADLEITFLLKICKKLSLAALVEVHDEREMGRVLGIEGIELVGINNRSLETFEVDISNTKKLLEGEHGRQIRERDMIVVGESGLFTPDDIAYVQAAGVKAVLVGESIVKQNDPEKGIAGLFGRNISHT
>PDB_1jcm_P Trpc stability mutant containing an engineered disulphide bridge and in complex with a cdrp-related substrate
MQCVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDALQGARTAFILECKKASPSKGVIRDDFDPARIAAIYKHY
ASAISVLTDEKYFQGSFNFLPIVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV
LTEVSNEEEQERAIALGAKVVGINNRDLCDLSIDLNRTRELAPKLGHNVTVISESGINTYAQVRELSHFANGFLIGSALM
AHDDLHAAVRRVLLGENKV
>ENA__AAB39010.1 indole-3-glycerol-phosphate synthase (Bradyrhizobium japonicum)
MSDILTKIETYKREEIAAAKRAQPLSVVEATAKAQGAPRGFLRAIKAKHTNGDFALIAEVKKASPSKGLIRADFDPPQFAKAYEAGGAACLSVLTDTPSFQGHLDFMVAARAATSLPVLRKDFMFDAYQVVEARAHGADCILIIMTALDDATAKDLEDTAIAFGMDVLIEIHDRAELDRALKLRSPMIGVNNRNLRTFETTLATSEALAPLIPGDRLMVGESGIFTPADLARLERVGMSTFLVGESLMRQADVTAATRTLLARETTARATGTR
>ENA__AAD09119.1 indole-3-glycerol phosphate synthase (Rhodobacter sphaeroides)
MSTILDRIKAYKLEEIAARKAERPLVAVEDAARAAPAPRGFARALSTAAATGYGLIAEIKKASPSKGLIREDFDVPALARAYETGGATCLSVLTDGPSFQGADDFLRQAREAVKLPCLRKDFLYDTYQVAEARALGADCILIIMASVTDSQALELEAAASHWGMDVLVEVHSREELARAEHLKSRLIGINNRNLDTFEVSLDVTRDLARRVPEDRLIVSESGLHTPEDLADLARYGARCFLIGESLMRQADVEAATRAILADPLTAQGGV
>biolip__6y88B Igps (indole-3-glycerol phosphate synthase) from pseudomonas aeruginosa in complex with substrate inhibitor rcdrp
SVPTVLQKILARKAEEVAERRARVNLAEVERLARSADAPRGFANALLERAKRKEPAVIAEIKKASPSKGVLREHFVPAEIARSYEAGGAACLSVLTDVDFFQGADAYLKEARAACALPVIRKDFMIDPYQIVEARAIGADCILLIVSALDDVLMAELAATAKSVGLDVLVEVHDGTELERALKTLDTPLVGINNRNLHTFEVSLETTLDLLPEIPRDRLVVTESGILNRADVELMEVSEVYAFLVGEAFMRADDPGLELKRLFFQ
>ENA__BAC65125.1 indole-3-glycerol phosphate synthase (Burkholderia multivorans)
MSDILDRIIAVKREEVAAAMRSTPLEALKLEASARDRRDFVGALRAKHAAGQPAVIAEIKKASPSKGVLREHFVPADIARSYAAHGAACLSVLTDEQFFQGSVRYLEEARAACDLPVLRKDFIVDAYQILEARAMGADAILLIAAALDTPLMQELEAYAHSLDLAVLVEVHDRNEMEQALTLKTPLLGINNRNLRTFETSIRATLDMLDMIPQDRIVVTESGILSRADVDTMRAANVNTFLVGEAFMRADQPGEELARMFF
>CharProtDB__CH_122586 anthranilate synthase component 2; EC 4.1.3.27 (Emericella nidulans)
MADTALVDHSPHHPTKAPRLETASNVILIDNYDSFTWNVYQYLVLEGATVTVIRNDEISLEELIAKKPTQLVVSPGPGHPKSDAGISNAAIQYFAGKIPIFGVCMGQQCIHHSFGGKVDVTGEILHGKTSVLKHDGRGAYEGLPPSVIITRYHSLAGTHSTIPECLEVSSFAQLGEDADKTVIMGVRHKQFAVEGVQFHPESILTEHGQTMFRNFLKLTAGTWEGNGKDVAQGGNFTAAAPNPPKATKQVSILEKIYDHRRAAVAKQKTIPSQRPSDLQAAYELSVAPPQISFPDRLRQSAYPLSLMAEIKRASPSKGLIAEHACAPAQARQYAKAGASVISVLTEPEWFKGSIDDLRAVRASLEGLTNRPAILRKEFIFDEYQILEARLAGADTVLLIVKMLDTELLTRLYLYSQSLGMEPLVEVNTPDEMKIAVDLGAQVIGVNNRDLTSFEVDLGTTSRLMDQVPESTIVCALSGISGPKDVEAYKKDGVKAILVGEALMRAPDTAAFVAELLGGQSKKLPLQSRNSPLVKICGTRTEEGARAAIEAGADLIGIILVEGRKRTVPDDVALQISKVVKSTPRPTPYPTEVPQGDTDATSVDYFDHSATTLRHPTRALLVGVFLNQPLSYVLAQQQKLGLDVVQLHGSEPLEWSRLIPVPVIRKFGLDEFGIARRAYHTVPLLDSGAGGSGELLDQMRVKQILKSDDGLRVILAGGLDPLNVTEIIKQLDESGYKIVGVDVSSGVETNGVQDLDKIRSFVQAAKSAF
>BRENDA__A1KJ27 indole-3-glycerol-phosphate synthase (EC 4.1.1.48) (Mycobacterium tuberculosis variant bovis BCG)
MSPATVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREPGIGVIAEVKRASPSAGALATIADPAKLAQAYQDGGARIVSVVTEQRRFQGSLDDLDAVRASVSIPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSVLVSMLDRTESLGMTALVEVHTEQEADRALKAGAKVIGVNARDLMTLDVDRDCFARIAPGLPSSVIRIAESGVRGTADLLAYAGAGADAVLVGEGLVTSGDPRAAVADLVTAGTHPSCPKPAR
>PDB_6y88_G Igps (indole-3-glycerol phosphate synthase) from pseudomonas aeruginosa in complex with substrate inhibitor rcdrp
AAAAAAAAAAAAAAVNLAEVERLARSADAPRGFANALLERAKRKEPAVIAEIKKASPSKGVLREHFVPAEIARSYEAGGA
ACLSVLTDQGADAYLKEARAACALPVIRKDFMIDPYQIVEARAIGADCILLIVSALDDVLMAELAATAKSVGLDVLVEVH
DGTELERALKTLDTPLVGINNRNLHTFEVSLETTLDLLPEIPRDRLVVTESGILNRADVELMEVSEVYAFLVGEAFMRAD
DPGLELKRLFFQE
>biolip__3t44A Crystal structure of mycobacterium tuberculosis indole glycerol phosphate synthase (igps) in complex with indole glycerol phosphate (igp) amd anthranilate
TVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREPGIGVIAEVKRASPSAGALATIADPAKLAQAYQDGGARIVSVVTEQRRFQGSLDDLDAVRASVSIPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSVLVSMLDRTESLGMTALVEVHTEQEADRALKAGAKVIGVNARDLMTLDVDRDCFARIAPGLPSSVIRIAESGVRGTADLLAYAGAGADAVLVGEGLVTSGDPRAAVADLVTAGT
>PDB_3t55_A Crystal structure of mycobacterium tuberculosis indole glycerol phosphate synthase (igps) in complex with phenoxymethyl benzoic acid (pmba)
TVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREPGIGVIAEVKRASPSAGALATIADPAKLAQAYQDG
GARIVSVVTEQRRFQGSLDDLDAVRASVSIPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSVLVSMLDRTESLGMT
ALVEVHTEQEADRALKAGAKVIGVNARDLMTLDVDRDCFARIAPGLPSSVIRIAESGVRGTADLLAYAGAGADAVLVGEG
LVTSGDPRAAVADLVTAG
>BRENDA__P84126 indole-3-glycerol-phosphate synthase (EC 4.1.1.48) (Thermus thermophilus)
MRPDLSRVPGVLGEIARKRASEVAPYPLPEPPSVPSFKEALLRPGLSVIAEVKRQSPSEGLIREVDPVEAALAYARGGARAVSVLTEPHRFGGSLLDLKRVREAVDLPLLRKDFVVDPFMLEEARAFGASAALLIVALLGELTGAYLEEARRLGLEALVEVHTERELEIALEAGAEVLGINNRDLATLHINLETAPRLGRLARKRGFGGVLVAESGYSRKEELKALEGLFDAVLIGTSLMRAPDLEAALRELVG
>PDB_3t78_A Crystal structure of mycobacterium tuberculosis indole glycerol phosphate synthase (igps) in complex with 5-fluoroanthranilate
TVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREPGIGVIAEVKRASPSAGALATIADPAKLAQAYQDG
GARIVSVVTEQRRFQGSLDDLDAVRASVSIPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSVLVSMLDRTESLGMT
ALVEVHTEQEADRALKAGAKVIGVNARDLMTLDRDCFARIAPGLPSSVIRIAESGVRGTADLLAYAGAGADAVLVGEGLV
TSGDPRAAVADLVTAGT
>metacyc__MONOMER-343 indole-3-glycerol phosphate synthase (EC 4.1.1.48) (Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8))
MRRLWEIVEAKKKDILEIDGENLIVQRRNHRFLEVLSGKERVKIIAEFKKASPSAGDINADASLEDFIRMYDELADAISILTEKHYFKGDPAFVRAARNLTCRPILAKDFYIDTVQVKLASSVGADAILIIARILTAEQIKEIYEAAEELGMDSLVEVHSREDLEKVFSVIRPKIIGINTRDLDTFEIKKNVLWELLPLVPDDTVVVAESGIKDPRELKDLRGKVNAVLVGTSIMKAENPRRFLEEMRAWSE
>SwissProt__P00937 Multifunctional tryptophan biosynthesis protein; EC 4.1.3.27; EC 4.1.1.48 (Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast))
MSVHAATNPINKHVVLIDNYDSFTWNVYEYLCQEGAKVSVYRNDAITVPEIAALNPDTLLISPGPGHPKTDSGISRDCIRYFTGKIPVFGICMGQQCMFDVFGGEVAYAGEIVHGKTSPISHDNCGIFKNVPQGIAVTRYHSLAGTESSLPSCLKVTASTENGIIMGVRHKKYTVEGVQFHPESILTEEGHLMIRNILNVSGGTWEENKSSPSNSILDRIYARRKIDVNEQSKIPGFTFQDLQSNYDLGLAPPLQDFYTVLSSSHKRAVVLAEVKRASPSKGPICLKAVAAEQALKYAEAGASAISVLTEPHWFHGSLQDLVNVRKILDLKFPPKERPCVLRKEFIFSKYQILEARLAGADTVLLIVKMLSQPLLKELYSYSKDLNMEPLVEVNSKEELQRALEIGAKVVGVNNRDLHSFNVDLNTTSNLVESIPKDVLLIALSGITTRDDAEKYKKEGVHGFLVGEALMKSTDVKKFIHELCE
>biolip__7etxA Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpc) from corynebacterium glutamicum
NNLPTVLESIVEGRRGHLEEIRARIAHVDVDALPKSTRSLFDSLNQGRGGARFIMECKSASPSLGMIREHYQPGEIARVYSRYASGISVLCEPDRFGGDYDHLATVAATSHLPVLCKDFIIDPVQVHAARYFGADAILLMLSVLDDEEYAALAAEAARFDLDILTEVIDEEEVARAIKLGAKIFGVNHRNLHDLSIDLDRSRRLSKLIPADAVLVSESGVRDTETVRQLGGHSNAFLVGSQLTSQENVDLAARELVYGPNKVCGLTSPSAAQTARAAGAVYGGLIFEEASPRNVSRETLQKIIAAEPNLRYVAVSRRTSGYKDLLVDGIFAVQIHAPLQDSVEAEKALIAAVREEVGPQVQVWRAISMSSPLGAEVAAAVEGDVDKLILDAHEGGSGEVFDWATVPAAVKAKSLLAGGISPDNAAQALAVGCAGLDINSGVEYPAGAGTWAGAKDAGALLKIFATISTFHYL
>PDB_7ety_A Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpc) from corynebacterium glutamicum in complex with reduced 1-(o-carboxyphenylamino)-1- deoxyribulose 5-phosphate (rcdrp)
LPTVLESIVEGRRGHLEEIRARIAHVDVDALPKSTRSLFDSLNQGRGGARFIMECKSASPSLGMIREHYQPGEIARVYSR
YASGISVLCEPDRFGGDYDHLATVAATSHLPVLCKDFIIDPVQVHAARYFGADAILLMLSVLDDEEYAALAAEAARFDLD
ILTEVIDEEEVARAIKLGAKIFGVNHRNLHDLSIDLDRSRRLSKLIPADAVLVSESGVRDTETVRQLGGHSNAFLVGSQL
TSQENVDLAARELVYGPNKVCGLTSPSAAQTARAAGAVYGGLIFEEASPRNVSRETLQKIIAAEPNLRYVAVSRRTSGYK
DLLVDGIFAVQIHAPLQDSVEAEKALIAAVREEVGPQVQVWRAISMSSPLGAEVAAAVEGDVDKLILDAHEGGSGEVFDW
ATVPAAVKAKSLLAGGISPDNAAQALAVGCAGLDINSGVEYPAGAGTWAGAKDAGALLKIFATISTFHYL
>PDB_3t40_A Crystal structure of mycobacterium tuberculosis indole glycerol phosphate synthase (igps) complex with n-2-carboxyphenyl glycine (cpg)
TVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREPGIGVIAEVKRTIADPAKLAQAYQDGGARIVSVVT
EQRRFQGSLDDLDAVRASVSIPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSVLVSMLDRTESLGMTALVEVHTEQ
EADRALKAGAKVIGVNARDVDRDCFARIAPGLPSSVIRIAESGVRGTADLLAYAGAGADAVLVGEGLVTSGDPRAAVADL
VTAGTHPSCPK
>metacyc__MONOMER-3581 indole-3-glycerol phosphate synthase (EC 4.1.1.48) (Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1))
MVFGLSRAIRKAEKNAIIAELKVYSPKYGDLLKGRNPFEILRAYERAGAVGISYITDPKYFRGSFEFLRKLCRETELPVLRKDFIASKEEVERTAEAGASAVLLITRLLKEELPEFVDFAKEHGLDTLVEVHSEEELAIALQTDSTMIGINNRDIGKLELDDGNVSLTEKLAPLIPKRYVKVSESGIAGTEDLKRALRHADAALIGTALMKTPDPEEFLRKLVEVEV
>PDB_1lbf_A Crystal structure of indole-3-glycerol phosphate syntase (igps)with reduced 1-(o-caboxyphenylamino)-1-deoxyribulose 5-phosphate (rcdrp)
PRYLKGWLKDVVQLSLRRPSFRASRQRPIISLNERILEFNKRNITAIIAEYKRKSPSGLDVERDPIEYSKFMERYAVGLS
ILTEEKYFNGSYETLRKIASSVSIPILMKDFIVKESQIDDAYNLGADTVLLIVKILTERELESLLEYARSYGMEPLIEIN
DENDLDIALRIGARFIGINSRDLETLEINKENQRKLISMIPSNVVKVAESGISERNEIEELRKLGVNAFLIGSSLMRNPE
KIKEFIL
>PDB_1juk_A Indole-3-glycerolphosphate synthase from sulfolobus solfataricus in a trigonal crystal form
PRYLKGWLKDVVQLSLRRPSFRASRQRPIISLNERILEFNKRNITAIIAEYKRKSPSGLDVERDPIEYSKFMERYAVGLS
ILTEEKYFNGSYETLRKIASSVSIPILMKDFIVKESQIDDAYNLGADTVLLIVKILTERELESLLEYARSYGMEPLIEIN
DENDLDIALRIGARFIGINSRDLETLEINKENQRKLISMIPSNVVKVAESGISERNEIEELRKLGVNAFLIGSSLMRNPE
KIKEFIL
>PDB_1igs_A Indole-3-glycerolphosphate synthase from sulfolobus solfataricus at 2.0 a resolution
PRYLKGWLKDVVQLSLRRPSFRASRQRPIISLNERILEFNKRNITAIIAEYKRKSPSGLDVERDPIEYSKFMERYAVGLS
ILTEEKYFNGSYETLRKIASSVSIPILMKDFIVKESQIDDAYNLGADTVLLIVKILTERELESLLEYARSYGMEPLIEIN
DENDLDIALRIGARFIGINSRDLETLEINKENQRKLISMIPSNVVKVAESGISERNEIEELRKLGVNAFLIGSSLMRNPE
KIKEFIL
>PDB_1a53_A Complex of indole-3-glycerolphosphate synthase from sulfolobus solfataricus with indole-3-glycerolphosphate at 2.0 a resolution
PRYLKGWLKDVVQLSLRRPSFRASRQRPIISLNERILEFNKRNITAIIAEYKRKSPSGLDVERDPIEYSKFMERYAVGLS
ILTEEKYFNGSYETLRKIASSVSIPILMKDFIVKESQIDDAYNLGADTVLLIVKILTERELESLLEYARSYGMEPLIEIN
DENDLDIALRIGARFIGINSRDLETLEINKENQRKLISMIPSNVVKVAESGISERNEIEELRKLGVNAFLIGSSLMRNPE
KIKEFIL
>BRENDA__P24920 phosphoribosylanthranilate isomerase (EC 5.3.1.24) (Phytophthora parasitica)
MGNILEEIAAQRRLDVAAAKQVVSTDDLAKKIEHTESVYGPALPVLERLNAPAEQVQAYANAGASMISVLTEPKWFKGSLDDMMEAREVVEGMSQRPAILRKDFIIDVYQLLEARAYGADCVLLIVTLLSKEQLIELIDATHNLGMCALVEVNSVQELDIALAAKARLIGVNNRDLRTFKVDMNTTARVADAIRERGLSLGRDGVALFALSGIRSHTDVVKYEKCGARGILVGEYLMKSGDIATTVKDLLQNVTRHSESGEFALLPPLAKVCGITTVEYALAALRNGANMIGIIMAEHSPRYVEKEEAKAIAKAVREYGERTGPILSDILESHLDDKSDWFHRNVLALREACSRAPLVVGVFVNKTATEMNAAAEEIGLDLVQLHGDEGFEICKDIKYPTIRALHLPDTAQCDGVDAEAVLQQVSEGLANYILLDTTVKGQQGGTGVAFDWKIAAIFTQARLPCLMAGGLTPENVVKALSVGHPVGVDVSSGVEVKGSPGVKDLDKVAAFLKAVKDHLSVATLKIDEETEN
>PDB_4iww_A Computational design of an unnatural amino acid metalloprotein with atomic level accuracy
PRYLKGWLEDVVQLSLRRPSVRASRQRPIISLNERILEFNKRNITAIIAEYKRKSPSGLDVERDPIEYAKFMERYAVGLS
ILTEEKYFNGSYETLRKIASSVSIPILMMDFIVKESQIDDAYNLGADTVLLAVKILTERELESLLEYARSYGMEPLIEIT
DENDLDIALRIGARFIGISSQDDETLEINKENQRKLISMIPSNVVKVADSGISERNEIEELRKLGVNAFLIGSSLMRNPE
KIKELIL
>PDB_5k7j_A Structure of designed zinc binding protein ze2 bound to zn2+
PRYLKGWLKDVVQLSLRRPSFRASRQRPIISLNERILEFNKRNITAIIAEYKRKSPSGLDVERDPIEYSKFMERYAVGLS
ILTEEKYFNGSYETLRKIASSVSIPILMADFIVKESQIDDAYNLGADTVLLIVKILTERELESLLEYARSYGMEPLIGIN
DENDLDIALRIGARFIGIHSHNKENQRKLISMIPSNVVKVAAHGISERNEIEELRKLGVNAFLIGSSLMRNPEKIKEFIL
>PDB_3uxd_A Designed protein ke59 r1 7/10h with dichlorobenzotriazole (dbt)
PRYLKGALKDVVQLSLRRPSLRASRQRPIISLRERILEFNKRNITAIIAVYKRKSPSGLDVERDPIEYAKFMERYAVGLV
ILTEEKYFNGSYEDLRKIASSVSIPILMWDFIVKESQIDDAYNLGADTVGLIVKILTERELESLLEYARSYGMEPAIVIN
DEEDLDIALRIGARIIIISSRDLETLEINKENQRKLISMIPSNVVKVAASGISERNEIEELRKLGVNAFEIGSSLMRNPE
KIKELIL
>PDB_4ou1_A Crystal structure of a computationally designed retro-aldolase covalently bound to folding probe 1 [(6-methoxynaphthalen-2-yl) (oxiran-2-yl)methanol]
PRYLKGWLEDVVQLSLRRPSVRASRQRPIISLNERILEFNKRNITAIIAEYKRKDPSGLDVERDPIEYAKFMERYAVGLF
ISTEEKYFNGSYETLRKIASSVSIPILMYDFIVKESQIDDAYNLGADTVALIVKILTERELESLLEYARSYGMEPLIIIN
DENDLDIALRIGARFIGIAARDWETGEINKENQRKLISMIPSNVVKVAKEGISERNEIEELRKLGVNAFLIGSSLMRNPE
KIKELIE
>biolip__3nz1A Crystal structure of kemp elimination catalyst 1a53-2 complexed with transition state analog 5-nitro benzotriazole
PRYLKGWLKDVVQLSLRRPSFRASRQRPIISLNERILEFNKRNITAIIAAYKRKSPSGLDVERDPIEYSKFMERYAVGLAIATEEKYFNGSYETLRKIASSVSIPILMWDFIVKESQIDDAYNLGADTVALIVKILTERELESLLEYARSYGMEPAIVINDENDLDIALRIGARFIEIASRDLETLEINKENQRKLISMIPSNVVKVAWQGISERNEIEELRKLGVNAFGIGSSLMRNPEKIKEFILGS
>biolip__3uz5A Designed protein ke59 r13 3/11h
PRYLKGWLEDVVQRSQRRPSVRASRQRPIISLKERILEFNKRNITAIMAVYKRKSPSGLDVERDPIEYAKFMERGVVGLAILTEEKYFNGSYEDLRKIASSVSVPILMWDIIVKESQIDDAYNLGADTVGLIVKILTERELESLLEYARSLGMEPAIVIHDENDLDIALRIGARFIIITSHDLETLEINNENQRKLISMIPSNVVKVVASGISERNEIEELYKLGVNAFEIGTSLMRNPEKIKEFIQ
>PDB_3uzj_A Designed protein ke59 r13 3/11h with benzotriazole
PRYLKGWLEDVVQRSQRRPSVRASRQRPIISLKERILEFNKRNITAIMAVYKRKSPSGLDVERDPIEYAKFMERGVVGLA
ILTEEKYFNGSYEDLRKIASSVSVPILMWDIIVKESQIDDAYNLGADTVGLIVKILTERELESLLEYARSLGMEPAIVIH
DENDLDIALRIGARFIIITSHDLETLEINNENQRKLISMIPSNVVKVVASGISERNEIEELYKLGVNAFEIGTSLMRNPE
KIKEFIQ
>PDB_6nw4_A Evolution of a computationally designed kemp eliminase
PRYLKGWLKDVVQLSLRRPSFRASRQRPIISLNERILEFNKRNITAIIAAYRRKSPCGLDVERDPIEYSKFMERYAVGLA
IATEEKYFNGSYETLRKIASSVSIPILMWDFIVKESQIDDAYNLGADTVALIVKILTERELESLLEYARSYGMEPYIVIN
DENDLDIALRIGARFIEICSRDFETLEINKENQRKLISMIPSNVVKVAWGGISERNEIEELRKLGVNAFGIGSSLMRNPE
KIKEFIL
>PDB_3ud6_A Structural analyses of covalent enzyme-substrate analogue complexes reveal strengths and limitations of de novo enzyme design
PRYLKGWLEDVVQLSLRRPSVRASRQRPIISLNERILEFNKRNITAIIATYMRKSPWGLDVERDPIEYAKFMERYAVGLS
ICTEEKYANGSYETLRKIASSVSIPILMADFIVKESQIDDAYNLGADTVPLIVKILTERELESLLEYARSYGMEPIIKIN
DENDLDIALRIGARFIGICSRDWETLEINKENQRKLISMIPSNVVKVASTGISERNEIEELRKLGVNAFSIISSLMRNPE
KIKELIEG
>biolip__4a2rA Structure of the engineered retro-aldolase ra95.5-5
PRYLKGWLEDVVQLSLRRPSVHASRQRPIISLNERILEFNKSNITAIIAYYTRKSPSGLDVERDPIEYAKFMERYAVGLSIKTEEKYFNGSYEMLRKIASSVSIPILMNDFIVKESQIDDAYNLGADTVLLIVKILTERELESLLEYARSYGMEPLILINDENDLDIALRIGARFISIFSMNFETGEINKENQRKLISMIPSNVVKVAKLGISERNEIEELRKLGVNAFLISSSLMRNPEKIKELIE
>PDB_5an7_A Structure of the engineered retro-aldolase ra95.5-8f with a bound 1,3- diketone inhibitor
PRYLKGWLEDVVQLSLRRPSVHASRQRPIISLNERILEFNKRNITAIIAYYLRKSPVERDPIEYAKYMEPYAVGLSIKTE
EKYFDGSYEMLRKIASSVSIPILMNDFIVKESQIDDAYNLGADTVLLIVEILTERELESLLEYARGYGMEPLILINDEND
LDIALRIGARFITIYSMNFETGEINKENQRKLISMIPSNVVKVPLLDFFEPNEIEELRKLGVNAFMISSSLMRNPEKIKE
LIE