Family Search for PF10164 (BRI3)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF10164 hits 5 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

BRI3_MOUSE / P28662 Membrane protein BRI3; Brain protein I3 from Mus musculus (Mouse)
Aligns to 28:124 / 125 (77.6%), covers 100.0% of PF10164, 121.4 bits

• function: Participates in tumor necrosis factor-alpha (TNF)-induced cell death (Ref.4). May be a target of Wnt/beta-catenin signaling in the liver (By similarity).
  subunit: Interacts with BRI3BP. Interacts with MGAT1 and IFITM3 (By similarity).

BRI3_HUMAN / O95415 Membrane protein BRI3; Brain protein I3; pRGR2 from Homo sapiens (Human) (see 4 papers)
Aligns to 28:124 / 125 (77.6%), covers 100.0% of PF10164, 118.5 bits

• function: Participates in tumor necrosis factor-alpha (TNF)-induced cell death (PubMed:14592447). May be a target of Wnt/beta-catenin signaling in the liver (PubMed:20538055).
  subunit: [Isoform 1]: Interacts with BRI3BP (PubMed:11860200, PubMed:30983867). Interacts with MGAT1 and IFITM3 (PubMed:30983867).
  subunit: [Isoform 2]: Interacts with BRI3BP, MGAT1 and IFITM3; the interactions are weaker than with isoform 1.

Or search for genetic data about PF10164 in the Fitness Browser