PaperBLAST
PaperBLAST Hits for BT4313 (89 a.a., MAHKKGVGSS...)
Show query sequence
>BT4313
MAHKKGVGSSKNGRESHSKRLGVKIFGGEACKAGNIIIRQRGTEFHPGENIGMGKDHTLF
ALVDGTVKFKVGREDRRYVSIIPAEATEA
Running BLASTp...
Found 140 similar proteins in the literature:
BF1009 50S ribosomal protein L27 from Bacteroides fragilis YCH46
97% identity, 100% coverage
PG0315 ribosomal protein L27 from Porphyromonas gingivalis W83
PGN_1647 putative 50S ribosomal protein L27 from Porphyromonas gingivalis ATCC 33277
PG_0315 50S ribosomal protein L27 from Porphyromonas gingivalis W83
73% identity, 91% coverage
- Microarray analysis of the transcriptional responses of Porphyromonas gingivalis to polyphosphate
Moon, BMC microbiology 2014 - “...50S ribosomal protein L19 3.23 PG0167 Ribosomal protein L25 1.86 PG0314 Ribosomal protein L21 1.90 PG0315 50S ribosomal protein L27 1.78 PG0385 Ribosomal protein S21 3.98 PG0592 50S ribosomal protein L31 4.01 PG0656 50S ribosomal protein L34 6.80 PG0989 50S ribosomal protein L20 3.43 PG0990 Ribosomal...”
- Gene expression profile analysis of Porphyromonas gingivalis during invasion of human coronary artery endothelial cells
Rodrigues, Infection and immunity 2005 - “...PG0121 PG0145 PG0176 PG0178 PG0186 PG0195 PG0272 PG0288 PG0315 PG0375 PG0389 PG0390 PG0392 PG0616 PG0618 PG0687 PG0689 PG0762 PG0779 PG0780 PG0992 PG1078 PG1084...”
- Synthesis of ppGpp impacts type IX secretion and biofilm matrix formation in Porphyromonas gingivalis
Kim, NPJ biofilms and microbiomes 2020 - “...2.10 PGN_0965 rplT 50S ribosomal protein L20 2.08 PGN_1580 rpsU 30S ribosomal protein S21 2.04 PGN_1647 rpmA 50S ribosomal protein L27 2.17 PGN_1648 rplU 50S ribosomal protein L21 2.06 PGN_1698 rpsO 30S ribosomal protein S15 2.45 PGN_1703 Ribonuclease III 1.98 PGN_1780 Putative translation initiation inhibitor, yjgF...”
- Pathway analysis for intracellular Porphyromonas gingivalis using a strain ATCC 33277 specific database
Hendrickson, BMC microbiology 2009 - “...(19) Decreased Levels (1) PGN_0035 PGN_0167 PGN_0640 PGN_0965 PGN_0394 PGN_0188 PGN_0279 PGN_1572 PGN_1589 PGN_0636 PGN_0639 PGN_1647 PGN_1648 PGN_0641 PGN_0964 PGN_1698 PGN_1844 PGN_1088 PGN_1219 PGN_1651 PGN_1852 PGN_1573 PGN_1575 PGN_1853 PGN_1854 PGN_1588 PGN_1590 PGN_1855 PGN_1861 PGN_1832 PGN_1840 PGN_1863 PGN_1868 PGN_1842 PGN_1843 PGN_1872 PGN_1890 PGN_1849 PGN_1850 PGN_1891 PGN_1856 PGN_1857...”
- A five-species transcriptome array for oral mixed-biofilm studies
Redanz, PloS one 2011 - “...(PG_1208), groES (PG_0521), groEL (PG_0521), clpL (PG_0010), clpX (PG_0417) and several ribosomal proteins, like L27 (PG_0315), S9 (PG_376), L1 (PG_391), and S6 (PG_595) (Supporting Table S1 ). Only 75 probes originating from 24 genes of the other species reacted nonspecifically (refer to Table 1 , Supporting...”
F452_RS0100215 50S ribosomal protein L27 from Porphyromonas gulae DSM 15663
73% identity, 91% coverage
Avin_40780 ribosomal protein L27 from Azotobacter vinelandii AvOP
71% identity, 94% coverage
RL4677 putative 50S ribosomal protein L27 from Rhizobium leguminosarum bv. viciae 3841
66% identity, 99% coverage
Q5H2E6 Large ribosomal subunit protein bL27 from Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
70% identity, 97% coverage
XP_002509506 50S ribosomal protein L27, chloroplastic from Ricinus communis
65% identity, 44% coverage
FE46_RS11385 50S ribosomal protein L27 from Flavobacterium psychrophilum
FP2216 50S ribosomal protein L27 from Flavobacterium psychrophilum JIP02/86
70% identity, 97% coverage
- Dual RNA-Seq of Flavobacterium psychrophilum and Its Outer Membrane Vesicles Distinguishes Genes Associated with Susceptibility to Bacterial Cold-Water Disease in Rainbow Trout (Oncorhynchus mykiss)
Chapagain, Pathogens (Basel, Switzerland) 2023 - “...L32 33.37 FE46_RS01825 30S ribosomal S16 30.62 FE46_RS01795 Inorganic pyrophosphatase 29.61 FE46_RS12455 Copper resistance 28.99 FE46_RS11385 50S ribosomal L27 23.06 FE46_RS05880 3,4-Dihydroxy-2-butanone-4-phosphate synthase 22.28 FE46_RS04555 30S ribosomal S6 21.17 FE46_RS04560 30S ribosomal S18 19.11 FE46_RS02470 Ribosome assembly cofactor 16.53 FE46_RS05480 NAD(P) FAD-dependent oxidoreductase 158.95 FE46_RS10070 Cytochrome-c...”
- Stress Tolerance-Related Genetic Traits of Fish Pathogen Flavobacterium psychrophilum in a Mature Biofilm
Levipan, Frontiers in microbiology 2018 - “...Epoxyqueuosine reductase (tRNA modification) queG , FP2124 GO:0005737, GO:0046872, GO:0051539, GO:0052693, GO:0008033, GO:0008616, GO:0055114 3.97 FP2216 50S ribosomal protein L27 rpmA GO:0005840, GO:0003735, GO:0006412 3.29 FP2217 50S ribosomal protein L21 rplU GO:0005840, GO:0003677, GO:0003735, GO:0019843, GO:0006281, GO:0006412 3.41 FP2380 50S ribosomal protein L32 rpmF GO:0015934, GO:0003735,...”
RLV_6941 50S ribosomal protein L27 from Rhizobium leguminosarum bv. viciae
64% identity, 99% coverage
BL1283 50S ribosomal protein L27 from Bifidobacterium longum NCC2705
71% identity, 92% coverage
bglu_1g04840 Ribosomal protein L27 from Burkholderia glumae BGR1
64% identity, 97% coverage
PA4567 50S ribosomal protein L27 from Pseudomonas aeruginosa PAO1
67% identity, 94% coverage
Bcep1808_0558 50S ribosomal protein L27 from Burkholderia vietnamiensis G4
A4JBB7 Large ribosomal subunit protein bL27 from Burkholderia vietnamiensis (strain G4 / LMG 22486)
66% identity, 97% coverage
- Differential Expression and PAH Degradation: What Burkholderia vietnamiensis G4 Can Tell Us?
Cauduro, International journal of microbiology 2020 - “...705 3-Oxoacid CoA-transferase subunit A Yes A4JAL3 Bcep1808_0303 336630..337727() 1098 hppD 4-Hydroxyphenylpyruvate dioxygenase Yes A4JBB7 Bcep1808_0558 614619..614882(+) 264 rpmA 50S ribosomal protein L27 Yes A4JQF7 Bcep1808_5572 122728..123519(+) 792 ABC transporter related Yes A4JA13 Bcep1808_0093 100965..101744(+) 780 ABC transporter-like protein Yes A4JA20 Bcep1808_0100 109204..110988(+) 1785 ABC transporter-like...”
- Differential Expression and PAH Degradation: What Burkholderia vietnamiensis G4 Can Tell Us?
Cauduro, International journal of microbiology 2020 - “...1537771..1538475(+) 705 3-Oxoacid CoA-transferase subunit A Yes A4JAL3 Bcep1808_0303 336630..337727() 1098 hppD 4-Hydroxyphenylpyruvate dioxygenase Yes A4JBB7 Bcep1808_0558 614619..614882(+) 264 rpmA 50S ribosomal protein L27 Yes A4JQF7 Bcep1808_5572 122728..123519(+) 792 ABC transporter related Yes A4JA13 Bcep1808_0093 100965..101744(+) 780 ABC transporter-like protein Yes A4JA20 Bcep1808_0100 109204..110988(+) 1785 ABC...”
VC0436 ribosomal protein L27 from Vibrio cholerae O1 biovar eltor str. N16961
69% identity, 96% coverage
BTH_I1141 ribosomal protein L27 from Burkholderia thailandensis E264
66% identity, 97% coverage
RK27_SPIOL / P82190 Large ribosomal subunit protein bL27c; 50S ribosomal protein L27, chloroplastic; CL27 from Spinacia oleracea (Spinach) (see 2 papers)
63% identity, 43% coverage
- function: Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
subunit: Component of the chloroplast large ribosomal subunit (LSU). Mature 70S chloroplast ribosomes of higher plants consist of a small (30S) and a large (50S) subunit. The 30S small subunit contains 1 molecule of ribosomal RNA (16S rRNA) and 24 different proteins. The 50S large subunit contains 3 rRNA molecules (23S, 5S and 4.5S rRNA) and 33 different proteins.
ssr2799 50S ribosomal protein L27 from Synechocystis sp. PCC 6803
62% identity, 97% coverage
- A transcriptional regulator Sll0794 regulates tolerance to biofuel ethanol in photosynthetic Synechocystis sp. PCC 6803
Song, Molecular & cellular proteomics : MCP 2014 - “...Ssl1784 Ssl3044 Ssl3432 Ssl3441 Ssl3445 Ssr0482 Ssr1604 Ssr2799 Mutant_r1 vs. Control_r1 Mutant_r2 vs. Control_r1 Mutant_r1 vs. Control_r2 Mutant_r2 vs....”
- Proteomic analysis reveals resistance mechanism against biofuel hexane in Synechocystis sp. PCC 6803
Liu, Biotechnology for biofuels 2012 - “...Sll1803 0.53 0.64 0.52 0.65 50S ribosomal protein L22 Sll1807 0.48 50S ribosomal protein L24 Ssr2799 0.00 0.58 50S ribosomal protein L27 Ssr1604 0.50 0.37 0.55 50S ribosomal protein L28 Sll1810 0.35 0.43 0.57 50S ribosomal protein L6 Sll1927 0.63 ABC transporter Slr1694 0.63 Activat or...”
- Gene expression patterns of sulfur starvation in Synechocystis sp. PCC 6803
Zhang, BMC genomics 2008 - “...ssl3432( rps19 ), ssl3436( rpl29 )) 14 Translation (ssr1480, ssl3441 ( infA ), Ribosomal protein ssr2799 ( rpl27 )) 15 sll1184( ho1 ), slr0444( aroA ), slr1176( agp ), sll0807( cfxE ), slr1545( rpoE ), Cytochrome b 6/f complex subunit smr0003( petM ), Photosystem I (smr0005(...”
Q8UBR6 Large ribosomal subunit protein bL27 from Agrobacterium fabrum (strain C58 / ATCC 33970)
64% identity, 99% coverage
LOC101776379 50S ribosomal protein L27, chloroplastic from Setaria italica
62% identity, 45% coverage
LIC12774 50S ribosomal protein L27 from Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
66% identity, 93% coverage
B6TM74 50S ribosomal protein L27 from Zea mays
62% identity, 47% coverage
O65037 Large ribosomal subunit protein bL27c from Oryza sativa subsp. japonica
62% identity, 44% coverage
CCNA_00320 LSU ribosomal protein L27P from Caulobacter crescentus NA1000
Q9ABB3 Large ribosomal subunit protein bL27 from Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15)
CC0318 ribosomal protein L27 from Caulobacter crescentus CB15
64% identity, 94% coverage
- The transcriptional landscape of a rewritten bacterial genome reveals control elements and genome design principles
van, Nature communications 2021 - “...biological block, omission of which is the main risk of decoupling. This also applies to CCNA_00320 and CCNA_00321, encoding LSU ribosomal protein L27P and L21P, respectively. We included the native 70 bp upstream of CETH_00320, of which 40bp encodes the 3 end of CCNA_00321. We observe...”
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria.
Wall, Molecular microbiology 2015 - “...T. indicus -YP_004625725, B. fragilis -BAD47759, D. radiodurans - Q9RY65, A. capsulatum -C1F354, C. crescentus -Q9ABB3, C. diphtheriae -YP_005165478, D. indicum - YP_004113510 E. coli -AAC76217, P. ingrahamii - A1SSB5. (C) Western blot analysis of L27 N-terminal cleavage. Plasmid-encoded S. aureus L27 carried C-terminal Myc and...”
- A top-down/bottom-up study of the ribosomal proteins of Caulobacter crescentus
Running, Journal of proteome research 2007 - “...the genome sequencing data.69,70 Ribosomal protein L27's gene (ORF CC0318) is terminated by the sequence GCC GAG TAA, coding for A-E-(Stop). Although TAA is the...”
B7C60_RS11050 50S ribosomal protein L27 from Vibrio fujianensis
70% identity, 91% coverage
HAPS_2069 50S ribosomal protein L27 from Haemophilus parasuis SH0165
67% identity, 93% coverage
- The pharmacokinetic-pharmacodynamic modeling and cut-off values of tildipirosin against Haemophilus parasuis
Lei, Oncotarget 2018 - “...macrolides may be associated with the pathways of amino acid ATP-binding cassette (ABC) transporter system (HAPS_2069, HAPS_RS03630) and the metabolite transporter superfamily (HAPS_2067 and HAPS_2068, HAPS_RS08950) [ 49 , 50 , 55 , 56 ], which will be a focus of future studies. Hence, all HPS...”
- Comparative transcriptional profiling of tildipirosin-resistant and sensitive Haemophilus parasuis
Lei, Scientific reports 2017 - “...has been associated with pathways of the amino acid ATP-binding cassette (ABC) transport system ( HAPS_2069 ) and the metabolite transporter superfamily ( HAPS_2067 , HAPS_2068 ). However, no studies have been conducted on the mechanisms of tildipirosin resistance in HPS . In the current study,...”
SMc03772 PROBABLE 50S RIBOSOMAL PROTEIN L27 from Sinorhizobium meliloti 1021
64% identity, 99% coverage
PP0689 ribosomal protein L27 from Pseudomonas putida KT2440
Pput_0721 50S ribosomal protein L27 from Pseudomonas putida F1
PP_0689 50S ribosomal protein L27 from Pseudomonas putida KT2440
66% identity, 94% coverage
VP0329 ribosomal protein L27 from Vibrio parahaemolyticus RIMD 2210633
68% identity, 91% coverage
YSS_RS00440 50S ribosomal protein L27 from Campylobacter coli RM4661
Cj0095 50S ribosomal protein L27 from Campylobacter jejuni subsp. jejuni NCTC 11168
65% identity, 94% coverage
ACIAD2938 50S ribosomal protein L27 from Acinetobacter sp. ADP1
66% identity, 91% coverage
8rd8VH / A0A0M4TUE5 8rd8VH (see paper)
68% identity, 90% coverage
LOC115699444 large ribosomal subunit protein bL27c from Cannabis sativa
60% identity, 45% coverage
- Genetic insights into agronomic and morphological traits of drug-type cannabis revealed by genome-wide association studies
de, Scientific reports 2024 - “...part of the same HB, spanning~97kb on chromosome 1. The SNP _26 was located within LOC115699444 without forming HBs. The 11 HBs spanned~250kb, within which 21 annotated genes were identified. Consequently, these genes were considered as putative candidates genes associated with different traits. Recent genome annotation...”
- “...LOC115696236 AT4G19840 Phloem protein 2-A1 LOC115697640 AT1G31190 Myo-inositol monophosphatase like 1 SNP_14 Chr08:57485105 Node counts LOC115699444 AT5G40950 RPL27 ribosomal protein large subunit 27 SNP_11 Chr09:3312257833123950 1.4 Stem diameter average LOC115724084 AT5G28840 Uncharacterized protein (mRNA) SNP_4 Chr09:5968987159691348 1.5 Dried flower weight/Canopy diameter/Height LOC115722258 AT5G42480 Accumulation and replication...”
Q18B22 Large ribosomal subunit protein bL27 from Clostridioides difficile (strain 630)
64% identity, 92% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...D5EEJ4; Bb L27, O51721; Bp L27, D8IEK6; Br L27, B5RQB7; Bs L27, P05657; Cd L27, Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9;...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex
Hotinger, Biochemistry 2022 - “...; Sa L27, Q2FXT0 ; Ec L27, P0A7L8 ; Bs L27, P05657 ; Cd L27, Q18B22 ; Ef L27, A0A132ZFM0 ; Lr L27, K8QHR9 ; Sm L27, Q8DUQ4 ; Sp L27, P66136 ; Fn L27, Q8REI3 ; Ac L27, D5EEJ4 ; Bb L27, O51721 ; Mp...”
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria.
Wall, Molecular microbiology 2015 - “...also contain a Prp homolog. Accession numbers: A. colombiense -ADE56976, C. trachomatis -P66123, C. difficile -Q18B22, M. pneumoniae -P75458, E. rhusiopathiae -YP_004561011, L. johnsonii -Q74IL5, E. faecium -AFK58391, S. pneumoniae -Q04KI2, B. subtilis -CAB14754, S. aureus -NP_374758, H. pylori -YP_006934224, F. nucleatum -WP_005917003, C. aggregans -B8G6X2,...”
BHE81_16205 50S ribosomal protein L27 from Klebsiella sp. AqSCr
64% identity, 93% coverage
HP0297 ribosomal protein L27 (rpl27) from Helicobacter pylori 26695
59% identity, 99% coverage
- The Role of a Dipeptide Transporter in the Virulence of Human Pathogen, Helicobacter pylori
Xu, Frontiers in microbiology 2021 - “...1.5474 HP0291 Predicted gene 1.2657 HP0292 Predicted gene 1.0587 HP0294 amiE 2.2148 HP0296 rplU 1.4814 HP0297 rpmA 1.4635 HP0298 dppA 4.9784 HP0299 dppB 1.4717 HP0300 dppC 2.088 HP0301 dppD 2.4619 HP0302 dppF 2.0374 HP0303 obgE A-3.1174 HP0304 Predicted gene 2.0838 HP0318 Predicted gene 1.2903 HP0364 nrdF...”
- Molecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana
Di, Viruses 2020 - “...- HP0274 pos f 43 539 + NA + - - CVA20 Enterovirus C AdV HP0297 pos f 36 655 + NA + + - EV-B74 Enterovirus B SaV HP0335 pos f 36 391 + NA - - - EV-C113 Enterovirus C SaV HP0361 pos f...”
- Use of Alignment-Free Phylogenetics for Rapid Genome Sequence-Based Typing of Helicobacter pylori Virulence Markers and Antibiotic Susceptibility
van, Journal of clinical microbiology 2015 - “...of the RpsT (HP0076), RpsI (HP0083), RplM (HP0084), RplT (HP0126), RpmF (HP0200), RplU (HP0296), RpmA (HP0297), RpmB (HP0491), RplI (HP0514), and RpmE (HP0551) amino acid sequences, followed by alignment and generation of phylogenetic trees with MEGA v5.2. FigTree ( http://tree.bio.ed.ac.uk/software/figtree/ ) was used for visualization of...”
- Aconitase Functions as a Pleiotropic Posttranscriptional Regulator in Helicobacter pylori
Austin, Journal of bacteriology 2015 - “...HP0913 HP1422 HP0786 HP1296 HP1468 HP0480 HP1048 HP0297 Gene Aconitase in Helicobacter TABLE 3 Putative targets for aconitase-mediated regulation Description...”
- Gene expression profiling of Helicobacter pylori reveals a growth-phase-dependent switch in virulence gene expression
Thompson, Infection and immunity 2003 - “...of California, Berkeley Transcription and translation HP0077f HP0297 HP1195d HP1196d HP1198d HP1199d HP1200d HP1292d HP1293d HP1294d HP1295d HP1296d HP1299d...”
B0SRT6 Large ribosomal subunit protein bL27 from Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)
61% identity, 93% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4;...”
NJ56_03870 50S ribosomal protein L27 from Yersinia ruckeri
YPO3511 50S ribosomal protein L27 from Yersinia pestis CO92
YPTB0465 50S ribosomal protein L27 from Yersinia pseudotuberculosis IP 32953
68% identity, 91% coverage
RK27_ARATH / Q9FLN4 Large ribosomal subunit protein bL27c; 50S ribosomal protein L27, chloroplastic; CL27 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
AT5G40950 RPL27 (RIBOSOMAL PROTEIN LARGE SUBUNIT 27); structural constituent of ribosome from Arabidopsis thaliana
60% identity, 42% coverage
- subunit: Part of the 50S ribosomal subunit
disruption phenotype: Embryonic lethality. Embryo development arrested at the globular stage. - Drought Stress Induces Morpho-Physiological and Proteome Changes of Pandanus amaryllifolius
Amnan, Plants (Basel, Switzerland) 2022 - “...Cysteine-type endopeptidase Hydrolase 1 P48711 Ribulose bisphosphate carboxylase large chain Photorespiration Magnesium ion binding 1 Q9FLN4 50S ribosomal protein L27, chloroplastic Ribonucleoprotein mRNA binding 1 A0A357 30S ribosomal protein S18, chloroplastic Ribonucleoprotein rRNA binding 1 A1E9N5 30S ribosomal protein S7, chloroplastic Ribonucleoprotein rRNA binding 1 O23760...”
- Disclosing proteins in the leaves of cork oak plants associated with the immune response to Phytophthora cinnamomi inoculation in the roots: A long-term proteomics approach
Coelho, PloS one 2021 - “...superfamily F4J3Q8 P10795 0.878 1.543 0.818 -3.1 Ribulose bisphosphate carboxylase small chain 1A, chloroplastic RBS1A/RBCS1A Q9FLN4 0.218 0.100 0.132 -1.5 50S ribosomal protein L27, chloroplastic RK27 Q9FZ47 1.255 0.641 0.065 -1.3 ACT domain-containing protein ACR11 ACR11 O04603 0.412 0.201 0.041 -1.2 50S ribosomal protein L5, chloroplastic...”
- Genetic insights into agronomic and morphological traits of drug-type cannabis revealed by genome-wide association studies
de, Scientific reports 2024 - “...AT4G19840 Phloem protein 2-A1 LOC115697640 AT1G31190 Myo-inositol monophosphatase like 1 SNP_14 Chr08:57485105 Node counts LOC115699444 AT5G40950 RPL27 ribosomal protein large subunit 27 SNP_11 Chr09:3312257833123950 1.4 Stem diameter average LOC115724084 AT5G28840 Uncharacterized protein (mRNA) SNP_4 Chr09:5968987159691348 1.5 Dried flower weight/Canopy diameter/Height LOC115722258 AT5G42480 Accumulation and replication of...”
- Construction and analysis of protein-protein interaction networks based on nuclear proteomics data of the desiccation-tolerant Xerophyta schlechteri leaves subjected to dehydration stress
Shoko, Communicative & integrative biology 2023 - “...AT4G02840 [Source:UniProtKB/TrEMBL;Acc: A0A178V1I1] gi|41019517 ATMG00070 NADH dehydrogenase subunit 9 [Source:TAIR;Acc:ATMG00070] gi|4406816 AT2G18020 EMB2296 [Source:UniProtKB/TrEMBL;Acc:A0A178VSS0] gi|21553582 AT5G40950 50S ribosomal protein L27, chloroplastic [Source:UniProtKB/Swiss-Prot;Acc:Q9FLN4] gi|27808637 AT3G60770 40S ribosomal protein S131 [Source:UniProtKB/Swiss-Prot;Acc:P59223] gi|98960873 AT3G09680 40S ribosomal protein S231 [Source:UniProtKB/Swiss-Prot;Acc:Q9SF35] gi|84028256 AT5G52650 40S ribosomal protein S103 [Source:UniProtKB/Swiss-Prot;Acc:Q9LTF2] gi|4218014 AT2G18510 Emb2444...”
- Global transcriptome and coexpression network analyses reveal cultivar-specific molecular signatures associated with different rooting depth responses to drought stress in potato
Qin, Frontiers in plant science 2022 - “...wound response, flower development, and syncytium formation ( Shigeto etal., 2014 ). The homologous genes AT5G40950 of PGSC0003DMG400019631 and AT5G56670 of PGSC0003DMG401002397 in Arabidopsis may encode ribosomal proteins and participate in protein synthesis ( Wang etal., 2008 ; Bach-Pages etal., 2020 ). The homologous gene of...”
- Plastid ribosome protein L5 is essential for post-globular embryo development in Arabidopsis thaliana
Dupouy, Plant reproduction 2022 - “...2012 ); Romani et al. ( 2012 ) L25 NA NA NA NA L27 Non-essential AT5G40950 Essential Romani et al. ( 2012 ) L28 Essential AT2G33450 Essential for greening process and post germination Romani et al. ( 2012 ) L29 Non-essential AT5G65220 NA NA L30 Non-essential...”
- Spaceflight induces novel regulatory responses in Arabidopsis seedling as revealed by combined proteomic and transcriptomic analyses
Kruse, BMC plant biology 2020 - “...0.012 AT1G79850 30S ribosomal protein S17, chloroplastic 1.02 0.002 AT5G20180 Ribosomal protein L36 1.03 0.019 AT5G40950 50S ribosomal protein L27, chloroplastic 1.05 0.002 AT2G24090 Ribosomal protein L35 1.06 0.001 AT4G11175 Translation initiation factor IF-1, chloroplastic 1.08 0.002 AT3G27160 Ribosomal protein S21 family protein 1.11 0.001 AT1G68590...”
- Separation and Paired Proteome Profiling of Plant Chloroplast and Cytoplasmic Ribosomes
Firmino, Plants (Basel, Switzerland) 2020 - “...NA ATCG01300 plastid 50S uL23c RPL23.2 + NA AT5G54600 plastid 50S uL24c RPL24 + NA AT5G40950 plastid 50S bL27c RPL27 + NA AT2G33450 plastid 50S bL28c RPL28 + NA AT5G65220 plastid 50S uL29c RPL29 + NA AT1G75350 plastid 50S bL31c RPL31 + NA ATCG01020 plastid 50S...”
- Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis
Liebthal, Antioxidants (Basel, Switzerland) 2020 - “...1 (AT2G44040) Adenylosuccinate synthetase (AT3G57610) CDPME kinase (AT2G26930) Ferredoxin--NADP reductase (AT1G20020) 50S ribosomal protein L27 (AT5G40950) Allene oxide synthase (AT5G42650) 50S ribosomal protein L29 (AT1G79850) Protein MET1 (AT1G55480) 50S ribosomal protein L5 (AT4G01310) AT5g64380/MSJ1_22 (AT5G64380) 60S ribosomal protein L26-1 (AT3G49910) Glutathione S-transferase F8 (AT2G47730) ATPase alpha...”
- Transcriptional analysis of sweet orange trees co-infected with 'Candidatus Liberibacter asiaticus' and mild or severe strains of Citrus tristeza virus
Fu, BMC genomics 2017 - “...L21, chloroplast/CL21 1.72 RPL24 orange1.1g029417m AT5G54600 50S ribosomal protein L24, chloroplast (CL24) 1.98 RPL27 orange1.1g029509m AT5G40950 ribosomal protein large subunit 27 1.01 RPL28 orange1.1g031725m AT2G33450 50S ribosomal protein L28, chloroplast (CL28) 1.42 RPL29 orange1.1g030809m AT5G65220 ribosomal protein L29 family protein 1.32 RPL34 orange1.1g031306m AT1G29070 ribosomal protein...”
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RPA0159 ribosomal protein L27 from Rhodopseudomonas palustris CGA009
64% identity, 92% coverage
- ATP Is a Major Determinant of Phototrophic Bacterial Longevity in Growth Arrest
Yin, mBio 2023 - “...gene under light and dark-incubated conditions. From left to right, 50S ribosome: RPA0038, RPA0039, RPA0158, RPA0159, RPA0241, RPA0493, RPA0526, RPA0634, RPA0918, RPA2767, RPA3080, RPA3129, RPA3225, RPA3231, RPA3232, RPA3234, RPA3235, RPA3238, RPA3239, RPA3240, RPA3242, RPA3243, RPA3245, RPA3247-RPA3250, RPA3269, RPA3270, RPA3272, RPA3273, RPA4197, RPA4356; 30S ribosome: RPA0064, RPA0244,...”
SENTW_3431 50S ribosomal protein L27 from Salmonella enterica subsp. enterica serovar Weltevreden str.
STM3303 50S ribosomal subunit protein L27 from Salmonella typhimurium LT2
SPC_3372 50S ribosomal protein L27 from Salmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594
SEN3136 50S ribosomal subunit protein L27 from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109
64% identity, 93% coverage
6eriAW / P82190 6eriAW (see paper)
62% identity, 72% coverage
ABBFA_000738 ribosomal protein L27 from Acinetobacter baumannii AB307-0294
B7GXH9 Large ribosomal subunit protein bL27 from Acinetobacter baumannii (strain AB307-0294)
65% identity, 91% coverage
K9U2M6 Large ribosomal subunit protein bL27 from Chroococcidiopsis thermalis (strain PCC 7203)
60% identity, 85% coverage
4v61BX 4v61BX (see paper)
60% identity, 94% coverage
HI0879 ribosomal protein L27 (rpL27) from Haemophilus influenzae Rd KW20
63% identity, 93% coverage
RL27_DEIRA / Q9RY65 Large ribosomal subunit protein bL27; 50S ribosomal protein L27 from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see 6 papers)
DR_0085 ribosomal protein L27 from Deinococcus radiodurans R1
62% identity, 98% coverage
- function: Binds the 5S and 23S rRNAs and also the tRNA in the P site
subunit: Part of the 50S ribosomal subunit. Contacts protein L18. - Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria.
Wall, Molecular microbiology 2015 - “...gonorrhoeae - AAW90302, B. burgdorferi -WP_002656482, T. indicus -YP_004625725, B. fragilis -BAD47759, D. radiodurans - Q9RY65, A. capsulatum -C1F354, C. crescentus -Q9ABB3, C. diphtheriae -YP_005165478, D. indicum - YP_004113510 E. coli -AAC76217, P. ingrahamii - A1SSB5. (C) Western blot analysis of L27 N-terminal cleavage. Plasmid-encoded S....”
- Essentiality of threonylcarbamoyladenosine (t(6)A), a universal tRNA modification, in bacteria
Thiaville, Molecular microbiology 2015 - “...). The most reduced protein in the mutant at mid log is ribosomal protein L27p (DR_0085) ( Table 4 ). The corresponding gene in E. coli is not essential, but mutants have greatly impaired growth rates, and are cold and heat sensitive ( Wower et al....”
- “...phenotype in D. radiodurans mutants is surprising, considering that the predicted fitness cost of a DR_0085 deletion is high ( Table 4 ). Using the MetaCyc Omics viewer ( Caspi et al. , 2014 ), enrichments in the down-regulated genes for the acetyl-coA to butyrate fermentation...”
C1F354 Large ribosomal subunit protein bL27 from Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / BCRC 80197 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)
58% identity, 99% coverage
RL27_THET8 / P60493 Large ribosomal subunit protein bL27; 50S ribosomal protein L27 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
5a9zAX / P60493 of Thermous thermophilus ribosome bound to BipA-GDPCP (see paper)
60% identity, 93% coverage
- function: Found on the solvent side of the large subunit
subunit: Part of the 50S ribosomal subunit - Ligand: rna (5a9zAX)
CAC1259 Ribosomal protein L27 from Clostridium acetobutylicum ATCC 824
60% identity, 88% coverage
D8IEK6 Large ribosomal subunit protein bL27 from Brachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000)
59% identity, 93% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...in alignments: gp46, A4ZFB2; gp47, A4ZBF3; L27: Ac L27, D5EEJ4; Bb L27, O51721; Bp L27, D8IEK6; Br L27, B5RQB7; Bs L27, P05657; Cd L27, Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6;...”
7uvvV / B7I6V8 7uvvV (see paper)
64% identity, 90% coverage
sync_2224 ribosomal protein L27 from Synechococcus sp. CC9311
59% identity, 96% coverage
P66123 Large ribosomal subunit protein bL27 from Chlamydia trachomatis serovar D (strain ATCC VR-885 / DSM 19411 / UW-3/Cx)
60% identity, 93% coverage
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria.
Wall, Molecular microbiology 2015 - “...L27 N-terminal extension also contain a Prp homolog. Accession numbers: A. colombiense -ADE56976, C. trachomatis -P66123, C. difficile -Q18B22, M. pneumoniae -P75458, E. rhusiopathiae -YP_004561011, L. johnsonii -Q74IL5, E. faecium -AFK58391, S. pneumoniae -Q04KI2, B. subtilis -CAB14754, S. aureus -NP_374758, H. pylori -YP_006934224, F. nucleatum -WP_005917003,...”
Rpz / b3185 50S ribosomal subunit protein L27 from Escherichia coli K-12 substr. MG1655 (see 32 papers)
rpmA / P0A7L8 50S ribosomal subunit protein L27 from Escherichia coli (strain K12) (see 28 papers)
RL27_ECOLI / P0A7L8 Large ribosomal subunit protein bL27; 50S ribosomal protein L27 from Escherichia coli (strain K12) (see 12 papers)
rpmA / BAA02526.1 ribosomal protein L27 from Escherichia coli (see 2 papers)
A0A140N340 Large ribosomal subunit protein bL27 from Escherichia coli (strain B / BL21-DE3)
NP_417652 50S ribosomal subunit protein L27 from Escherichia coli str. K-12 substr. MG1655
b3185 50S ribosomal protein L27 from Escherichia coli str. K-12 substr. MG1655
c3942 50S ribosomal protein L27 from Escherichia coli CFT073
ECs4064 50S ribosomal subunit protein L27 from Escherichia coli O157:H7 str. Sakai
63% identity, 91% coverage
- subunit: Part of the 50S ribosomal subunit (PubMed:10094780, PubMed:1225626, PubMed:12809609, PubMed:16272117, PubMed:24844575, PubMed:25310980, PubMed:27906160, PubMed:27906161, PubMed:27934701). Cross-links to the 23S rRNA (PubMed:6170935, PubMed:7556101). Cross- links to the A and P site tRNAs (PubMed:8524654).
- CRP and IHF act as host regulators in Royal Jelly's antibacterial activity
Xia, Scientific reports 2024 - “...Ribosomal subunit protein L4 rplD 0.44 3.68E07 P0AA10 Ribosomal subunit protein L13 rplM 0.46 6.53E06 P0A7L8 Ribosomal subunit protein L27 rpmA 0.46 1.58E04 P0A7N4 Ribosomal subunit protein L32 rpmF 0.46 3.01E04 P0A7K2 Ribosomal subunit protein L12 rplL 0.47 4.67E07 P61175 Ribosomal subunit protein L22 rplV 0.47...”
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...D8IEK6; Br L27, B5RQB7; Bs L27, P05657; Cd L27, Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1;...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex
Hotinger, Biochemistry 2022 - “...used in alignments: gp46, A4ZFB2 ; gp47, A4ZBF3 ; Sa L27, Q2FXT0 ; Ec L27, P0A7L8 ; Bs L27, P05657 ; Cd L27, Q18B22 ; Ef L27, A0A132ZFM0 ; Lr L27, K8QHR9 ; Sm L27, Q8DUQ4 ; Sp L27, P66136 ; Fn L27, Q8REI3 ; Ac...”
- Interplay between bacterial 5'-NAD-RNA decapping hydrolase NudC and DEAD-box RNA helicase CsdA in stress responses
Mickutė, mSystems 2023 - “...ribosome subunit protein L22 ++ ++ ++ ++ C6EGE8 50S ribosome subunit protein L23 + A0A140N340 50S ribosome subunit protein L27 ++ ++ A0A140N3L9 50S ribosome subunit protein L28 ++ ++ ++ A0A140N7F5 50S ribosome subunit protein L29 ++ ++ A0A140NAZ2 50S ribosome subunit protein L32...”
- Coexpression of Escherichia coli obgE, Encoding the Evolutionarily Conserved Obg GTPase, with Ribosomal Proteins L21 and L27.
Maouche, Journal of bacteriology 2016 - GeneRIF: obgE is cotranscribed with ribosomal protein genes rplU and rpmA.
- The primary structure of protein L27 from the peptidyl-tRNA binding site of Escherichia coli ribosomes.
Chen, FEBS letters 1975 (PubMed)- GeneRIF: N-terminus verified by Edman degradation on mature peptide
- In vitro transcription profiling of the σS subunit of bacterial RNA polymerase: re-definition of the σS regulon and identification of σS-specific promoter sequence elements
Maciag, Nucleic acids research 2011 - “...Ribosomal protein L21, in rplU-rpmA operon b3186 2.50 rpmA Ribosomal protein L27, in rplU-rpmA operon b3185 2.58 rpsU Ribosomal protein S21 b3065 2.78 Upregulated in a biofilm-growing rpoS mutant derivative of MG1655 ( 18 ) IG3426400_3426656-r Intergenic region including rrnH promoter N.A. 2.87 DNA repair sulA...”
- Microarray analysis of orthologous genes: conservation of the translational machinery across species at the sequence and expression level
Jiménez, Genome biology 2003 - “...protein Transcription and translation b3170 No COG0779 S Hypothetical 16.8 kD protein Ribosomal protein 7 b3185 Yes* COG0211 J4 Ribosomal protein L27 Ribosomal protein 7 b3186 No COG0261 J4 Ribosomal protein L21 Ribosomal protein 8 b3230 Yes** COG0103 J3 30S ribosomal protein S9 Ribosomal protein 8...”
- Combined, functional genomic-biochemical approach to intermediary metabolism: interaction of acivicin, a glutamine amidotransferase inhibitor, with Escherichia coli K-12
Smulski, Journal of bacteriology 2001 - “...vacJ xseA ygiC yjjR yjjS yjjT zwf b3318 b3309 b2185 b3185 b3637 b3302 b3636 b3703 b3299 b3295 b3314 b3296 b3303 b4200 b3341 b3306 b3230 b3321 b3297 b3298 b3307...”
- Genome-wide transcriptional profiling of the Escherichia coli responses to superoxide stress and sodium salicylate
Pomposiello, Journal of bacteriology 2001 - “...b3310 b3301 b3313 b3294 b3304 b3186 b3315 b3318 b3309 b3185 b3637 b3312 b3302 b1717 b3299 b3295 b0169 b3314 b3296 b3303 b3306 b3230 b3321 b3297 b3307 b2609...”
- In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA
Haugen, Infection and immunity 2007 - “...c2325 c1040 c4064 c4081 c2072 c3306 c2722 c5138 c4067 c3942 c4957 c4587 c1406 c3232 c3253 c3127 c0764 c0018 c1796 c2385 c0464 c3944 c4661 c1907 c0864 Gene 284...”
- Global transcriptional response of Escherichia coli O157:H7 to growth transitions in glucose minimal medium
Bergholz, BMC microbiology 2007 - “...yhbO 3.67 2 ECs3339 nlpB -2.13 1 ECs4040 yhbV -3.40 1 ECs3369 guaA -2.99 1 ECs4064 rpmA -3.29 1 ECs3397 - 2.55 2 ECs4068 murA -3.01 1 ECs3401 csiE 3.77 2 ECs4069 yrbA -2.73 1 ECs3409 yphA 3.07 2 ECs4091 gltB -3.19 1 ECs3434 lepB -2.08...”
4v4gBX 4v4gBX (see paper)
63% identity, 94% coverage
FTN_0676 ribosomal protein L27 from Francisella tularensis subsp. novicida U112
67% identity, 91% coverage
8cd1W / Q9HVL7 8cd1W (see paper)
66% identity, 84% coverage
B8G6X2 Large ribosomal subunit protein bL27 from Chloroflexus aggregans (strain MD-66 / DSM 9485)
59% identity, 95% coverage
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria.
Wall, Molecular microbiology 2015 - “...-Q04KI2, B. subtilis -CAB14754, S. aureus -NP_374758, H. pylori -YP_006934224, F. nucleatum -WP_005917003, C. aggregans -B8G6X2, L. ferroxidans -WP_014448398, T. lettingae -ABV34531, D. thermophilum -B5YEQ2, A. aeolicus -O67650, C. exile -YP_005473593, P. marinus -Q7V0C1, D. acetiphilus -ADD66838, P. mikurensis -BAM03335, N. gonorrhoeae - AAW90302, B. burgdorferi...”
A0A1T4M509 Large ribosomal subunit protein bL27 from Eubacterium ruminantium
62% identity, 91% coverage
EAMY_0333 50S ribosomal protein L27 from Erwinia amylovora CFBP1430
61% identity, 93% coverage
FN1119 LSU ribosomal protein L27P from Fusobacterium nucleatum subsp. nucleatum ATCC 25586
Q8REI3 Large ribosomal subunit protein bL27 from Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
62% identity, 86% coverage
- Proteomics of Fusobacterium nucleatum within a model developing oral microbial community
Hendrickson, MicrobiologyOpen 2014 - “...FN1546, FN1555, FN1556, FN1621, FN2020. 2 Covers FN0284, FN0325, FN0326, FN0329, FN0330, FN0430, FN0482, FN1117, FN1119, FN1282, FN1284, FN1285, FN1286, FN1364, FN1392, FN1437, FN1557, FN1558, FN1620, FN1623, FN1625, FN1626, FN1627, FN1628, FN1629, FN1630, FN1631, FN1632, FN1634, FN1635, FN1637, FN1638, FN1639, FN1640, FN1641, FN1642, FN1643, FN1644, FN1645,...”
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4;...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex.
Hotinger, Biochemistry 2022 - “...; Lr L27, K8QHR9 ; Sm L27, Q8DUQ4 ; Sp L27, P66136 ; Fn L27, Q8REI3 ; Ac L27, D5EEJ4 ; Bb L27, O51721 ; Mp L27, P47476 ; Tm L27, Q9X1G7 . PDB entries: covalently bound Sa Prp, 7KLD ; unliganded Sa Prp, 4PEO ;...”
D7024_12385 50S ribosomal protein L27 from Desulfofundulus salinus
58% identity, 100% coverage
8a3lv / P0A7L8 8a3lv (see paper)
63% identity, 90% coverage
MSMEG_4624, MSMEI_4507 50S ribosomal protein L27 from Mycolicibacterium smegmatis MC2 155
A0R150 Large ribosomal subunit protein bL27 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
MSMEG_4624 ribosomal protein L27 from Mycobacterium smegmatis str. MC2 155
58% identity, 100% coverage
- Interactome Analysis Identifies MSMEI_3879 as a Substrate of Mycolicibacterium smegmatis ClpC1
Ogbonna, Microbiology spectrum 2023 - “...0.02 A0QSL5 rpsM , MSMEG_1521, MSMEI_1485 30S ribosomal protein S13 0.04 0.04 A0R150 rpmA , MSMEG_4624, MSMEI_4507 50S ribosomal protein L27 0.02 0.02 A0QVB9 tsf , MSMEG_2520, MSMEI_2461 Elongation factor Ts (EF-Ts) 0.03 0.04 A0QSD0 rpsJ , MSMEG_1435, MSMEI_1399 30S ribosomal protein S10 0.11 0.02 0.17...”
- “...A0QSL5 rpsM , MSMEG_1521, MSMEI_1485 30S ribosomal protein S13 0.04 0.04 A0R150 rpmA , MSMEG_4624, MSMEI_4507 50S ribosomal protein L27 0.02 0.02 A0QVB9 tsf , MSMEG_2520, MSMEI_2461 Elongation factor Ts (EF-Ts) 0.03 0.04 A0QSD0 rpsJ , MSMEG_1435, MSMEI_1399 30S ribosomal protein S10 0.11 0.02 0.17 0.24...”
- Interactome Analysis Identifies MSMEI_3879 as a Substrate of Mycolicibacterium smegmatis ClpC1
Ogbonna, Microbiology spectrum 2023 - “...0.03 0.03 0.15 0.02 A0QSL5 rpsM , MSMEG_1521, MSMEI_1485 30S ribosomal protein S13 0.04 0.04 A0R150 rpmA , MSMEG_4624, MSMEI_4507 50S ribosomal protein L27 0.02 0.02 A0QVB9 tsf , MSMEG_2520, MSMEI_2461 Elongation factor Ts (EF-Ts) 0.03 0.04 A0QSD0 rpsJ , MSMEG_1435, MSMEI_1399 30S ribosomal protein S10...”
- Gene Expression, Bacteria Viability and Survivability Following Spray Drying of Mycobacterium smegmatis
Lauten, Materials (Basel, Switzerland) 2010 - “...L24 rplX 1.1 12.0 0.001 96% MSMEG_5431 ribosomal protein L25, Ctc-form 1.9 11.3 0.000 99% MSMEG_4624 ribosomal protein L27 rpmA 0.2 12.9 0.324 0% MSMEG_6068 ribosomal protein L28 rpmB 0.1 9.8 0.734 0% MSMEG_2400 ribosomal protein L28 rpmB 1.5 12.8 0.000 99% MSMEG_1444 ribosomal protein L29...”
A1SSB5 Large ribosomal subunit protein bL27 from Psychromonas ingrahamii (strain DSM 17664 / CCUG 51855 / 37)
63% identity, 92% coverage
Q9Z807 Large ribosomal subunit protein bL27 from Chlamydia pneumoniae
54% identity, 96% coverage
- Prediction of Chlamydia pneumoniae protein localization in host mitochondria and cytoplasm and possible involvements in lung cancer etiology: a computational approach
Alshamsan, Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2017 - “...in our study including L10 (Q9Z9A2), L9 (Q9Z6V3), L4 (Q9Z7Q8), L5 (Q9Z7R9), L29 (Q9Z7R5), L27 (Q9Z807), L33 (Q9Z8T4), L34 (Q9Z6X1) and L35 (Q9Z6R8), L36 (Q9Z6X0), which potentially involved in various steps of translation and ribosome biogenesis in C. pneumoniae . Control of translation is a critical...”
A5KLI2 Large ribosomal subunit protein bL27 from [Ruminococcus] torques ATCC 27756
61% identity, 88% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1;...”
Q7V0C1 Large ribosomal subunit protein bL27 from Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)
PMM1345 50S ribosomal protein L27 from Prochlorococcus marinus sp. MED4
61% identity, 92% coverage
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria.
Wall, Molecular microbiology 2015 - “...-WP_014448398, T. lettingae -ABV34531, D. thermophilum -B5YEQ2, A. aeolicus -O67650, C. exile -YP_005473593, P. marinus -Q7V0C1, D. acetiphilus -ADD66838, P. mikurensis -BAM03335, N. gonorrhoeae - AAW90302, B. burgdorferi -WP_002656482, T. indicus -YP_004625725, B. fragilis -BAD47759, D. radiodurans - Q9RY65, A. capsulatum -C1F354, C. crescentus -Q9ABB3, C....”
- A Cyanophage MarR-Type Transcription Factor Regulates Host RNase E Expression during Infection
Lambrecht, Microorganisms 2022 - “...(PMM1535) 97,779 0 97,779 rbcL (PMM0549) 97,015 393 96,622 rpoC1 (PMM1484) 93,962 0 93,962 rpl27 (PMM1345) 119,740 30,858 88,882 PMM0599 88,057 0 88,057 bait protein 2,051,700 2,051,700 0 microorganisms-10-02245-t002_Table 2 Table 2 Overview of the tested interactions between pMarR and potential interaction partners by yeast two-hybrid...”
7jilW / A0A1M6R2K9 7jilW (see paper)
66% identity, 83% coverage
SYNW0546 50S ribosomal protein L27 from Synechococcus sp. WH 8102
57% identity, 94% coverage
C9Z7H3 Large ribosomal subunit protein bL27 from Streptomyces scabiei (strain 87.22)
58% identity, 94% coverage
O67650 Large ribosomal subunit protein bL27 from Aquifex aeolicus (strain VF5)
56% identity, 90% coverage
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria.
Wall, Molecular microbiology 2015 - “...-WP_005917003, C. aggregans -B8G6X2, L. ferroxidans -WP_014448398, T. lettingae -ABV34531, D. thermophilum -B5YEQ2, A. aeolicus -O67650, C. exile -YP_005473593, P. marinus -Q7V0C1, D. acetiphilus -ADD66838, P. mikurensis -BAM03335, N. gonorrhoeae - AAW90302, B. burgdorferi -WP_002656482, T. indicus -YP_004625725, B. fragilis -BAD47759, D. radiodurans - Q9RY65, A....”
E7FUU3 Large ribosomal subunit protein bL27 from Erysipelothrix rhusiopathiae ATCC 19414
61% identity, 89% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89;...”
Q9X1G7 Large ribosomal subunit protein bL27 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
59% identity, 91% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2; Uu L27, B5ZB18; Prp: Ac Prp, D5EEJ5; Bb Prp, A0A0H3C0W4; Bp Prp, D8IEK5; Br Prp, B5RQB6; Bs Prp, P26942; Cd Prp, A0A031WH70; Ct Prp,...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex
Hotinger, Biochemistry 2022 - “...; Ac L27, D5EEJ4 ; Bb L27, O51721 ; Mp L27, P47476 ; Tm L27, Q9X1G7 . PDB entries: covalently bound Sa Prp, 7KLD ; unliganded Sa Prp, 4PEO ; Sm Prp, 2G0I ; Sp Prp, 2IDL ; Tm Prp, 1S1L . Author Contributions A.E.M. and...”
DVU0928 ribosomal protein L27 from Desulfovibrio vulgaris Hildenborough
55% identity, 98% coverage
C4Z9Z8 Large ribosomal subunit protein bL27 from Agathobacter rectalis (strain ATCC 33656 / DSM 3377 / JCM 17463 / KCTC 5835 / VPI 0990)
60% identity, 87% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis.
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...P05657; Cd L27, Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0;...”
8v9kY / A0R150 8v9kY (see paper)
60% identity, 92% coverage
SCO2596 50S ribosomal protein L27 from Streptomyces coelicolor A3(2)
58% identity, 93% coverage
B5RQB7 Large ribosomal subunit protein bL27 from Borrelia recurrentis (strain A1)
62% identity, 92% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...A4ZFB2; gp47, A4ZBF3; L27: Ac L27, D5EEJ4; Bb L27, O51721; Bp L27, D8IEK6; Br L27, B5RQB7; Bs L27, P05657; Cd L27, Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5;...”
ML1466 50S ribosomal protein L27 from Mycobacterium leprae TN
57% identity, 98% coverage
BB0780 ribosomal protein L27 (rpmA) from Borrelia burgdorferi B31
O51721 Large ribosomal subunit protein bL27 from Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
61% identity, 92% coverage
- Correction: Characterization of the RelBbu regulon in Borrelia burgdorferi reveals modulation of glycerol metabolism by (p)ppGpp
PLOS, PloS one 2015 - “...G ( fus-2 ) 0.96 0.001 BB0778 ribosomal protein L21 ( rplU ) 1.51 0.002 BB0780 ribosomal protein L27 ( rpmA ) 1.03 <0.001 Motility/chemotaxis BB0147 flagellar filament 41 kDa core protein ( flaB ) -1.31 0.001 BB0181 flagellar hook-associated protein ( flgK ) -1.14 0.010...”
- Characterization of the RelBbu Regulon in Borrelia burgdorferi Reveals Modulation of Glycerol Metabolism by (p)ppGpp
Bugrysheva, PloS one 2015 - “...G ( fus-2 ) 0.96 0.001 BB0778 ribosomal protein L21 ( rplU ) 1.51 0.002 BB0780 ribosomal protein L27 ( rpmA ) 1.03 <0.001 Motility/chemotaxis BB0147 flagellar filament 41 kDa core protein ( flaB ) -1.31 0.001 BB0181 flagellar hook-associated protein ( flgK ) -1.14 0.010...”
- Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals
Brooks, Infection and immunity 2003 - “...L11 [rplK] [Thermotoga maritima]) BBJ23 (hypothetical protein) BB0780 (ribosomal protein L27 [rpmA] [H. influenzae]) BB0697 (conserved hypothetical protein [H....”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex.
Hotinger, Biochemistry 2022 - “...; Sp L27, P66136 ; Fn L27, Q8REI3 ; Ac L27, D5EEJ4 ; Bb L27, O51721 ; Mp L27, P47476 ; Tm L27, Q9X1G7 . PDB entries: covalently bound Sa Prp, 7KLD ; unliganded Sa Prp, 4PEO ; Sm Prp, 2G0I ; Sp Prp, 2IDL ;...”
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis.
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...Codes: Proteins used in alignments: gp46, A4ZFB2; gp47, A4ZBF3; L27: Ac L27, D5EEJ4; Bb L27, O51721; Bp L27, D8IEK6; Br L27, B5RQB7; Bs L27, P05657; Cd L27, Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3;...”
A1KLD7 Large ribosomal subunit protein bL27 from Mycobacterium bovis (strain BCG / Pasteur 1173P2)
MT2517 50S ribosomal protein L27 from Mycobacterium tuberculosis CDC1551
Rv2441c 50S ribosomal protein L27 from Mycobacterium tuberculosis H37Rv
59% identity, 92% coverage
- HflX is a GTPase that controls hypoxia-induced replication arrest in slow-growing mycobacteria
Ngan, Proceedings of the National Academy of Sciences of the United States of America 2021 (secret) - Conserved codon composition of ribosomal protein coding genes in Escherichia coli, Mycobacterium tuberculosis and Saccharomyces cerevisiae: lessons from supervised machine learning in functional genomics
Lin, Nucleic acids research 2002 - “...MT2972, MT0731, MT1681, MT2518, MT0733, MT0730, MT0741.1, MT2517, MT3052.2, MT2118, MT0114, MT0736, MT0728, MT0747, MT1337, MT2117.1, MT0663, MT4041.1, MT1680,...”
- Role of VapBC12 Toxin-Antitoxin Locus in Cholesterol-Induced Mycobacterial Persistence
Talwar, mSystems 2020 - “...Information pathways 66.66666667 Rv2056c Information pathways 66.66666667 Rv1643 Information pathways 66.66666667 Rv0722 Information pathways 100 Rv2441c Information pathways 100 Rv3053c Information pathways 100 Rv3462c Information pathways 100 Rv1772 Conserved hypotheticals 60 Rv0678 Conserved hypotheticals 60 Rv0607 Conserved hypotheticals 60 Rv3678A Conserved hypotheticals 60 Rv1590 Conserved hypotheticals...”
- Transcriptional profile of Mycobacterium tuberculosis replicating in type II alveolar epithelial cells
Ryndak, PloS one 2015 - “...5/36 genes encoding 50S ribosomal proteins (Rv0714- rplN , Rv0716- rplE , Rv1298- rpmE , Rv2441c- rpmA , Rv3456c- rplQ ) were upregulated by M . tb in type II AEC ( Table 4 ) while 16/36 are downregulated by M . tb in activated macrophages...”
- Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
Hatzios, Proceedings of the National Academy of Sciences of the United States of America 2013 - “...Rv1980c Rv1996 Rv2050 Rv2190c Rv2271 Rv2301 Rv2348c Rv2391 Rv2412 Rv2441c Rv2442c Rv2745c Rv2783c Rv2889c 2.7 2.1 2.1 4.0 2.4 2.6 3.1 3.3 2.7 2.8 2.9 2.6 2.5...”
- Mycobacterium tuberculosis septum site determining protein, Ssd encoded by rv3660c, promotes filamentation and elicits an alternative metabolic and dormancy stress response
England, BMC microbiology 2011 - “...rpmD -0.9 -0.3 Rv3546 fadA5 1.1 0.1 Rv0723 rplO -0.7 -0.2 Rv1715 fadB3 1.0 -0.1 Rv2441c rpmA -0.9 -0.5 Rv0099 fadD10 1.2 0.0 Rv3442c rpsI -0.9 -0.2 Rv1550 fadD11 1.0 0.2 Rv3443c rplM -1.6 -0.5 Rv1058 fadD14 1.2 0.0 Rv3458c rpsD -0.8 -0.5 Rv3561 fadD3 0.8...”
- Biochemical and physiological characterization of the GTP-binding protein Obg of Mycobacterium tuberculosis
Sasindran, BMC microbiology 2011 - “...of M . tuberculosis , between the genes proB ( Rv2439c ) and rpmA ( Rv2441c ). The deduced amino acid sequence of the M. tuberculosis Obg protein shows significant similarities with the Obg proteins of B. subtilis , S. coelicolor and other bacterial species (Additional...”
AT5G15220 ribosomal protein L27 family protein from Arabidopsis thaliana
55% identity, 55% coverage
- BCL7A and BCL7B potentiate SWI/SNF-complex-mediated chromatin accessibility to regulate gene expression and vegetative phase transition in plants
Lei, Nature communications 2024 - “...Validation of ChIP-seq signals at representative loci by ChIP-qPCR. TA3 serves as a negative control. AT5G15220 that showed maintained binding signal serves as the control locus. Error bars are presented as means.d. from three biological replicates. P values were calculated with the two-tailed Students t test....”
- Transposed genes in Arabidopsis are often associated with flanking repeats
Woodhouse, PLoS genetics 2010 - “...AT5G44430 69 direct yes within transposed sequence yes yes AT2G16930 ribosomal protein L27 family protein AT5G15220 72 direct yes RNA recognition motif (RRM)-containing protein no no AT3G10845 RNA recognition motif (RRM)-containing protein AT5G41690 79 direct yes hydroxyacylglutathione hydrolase no no AT4G01640 F-box associated type 1 AT2G34280...”
- “...sequence homologous to the flanking repeats. In fact, in three of our transposed genes (AT2G34290, AT5G15220, and AT2G26010), a portion of the flanking sequence was found in both the A. lyrata orthologous target sequence and the parental sequence, suggesting the possibility that this same repeat sequence...”
AT2G16930 ribosomal protein L27 family protein from Arabidopsis thaliana
56% identity, 54% coverage
- An Update on Mitochondrial Ribosome Biology: The Plant Mitoribosome in the Spotlight
Tomal, Cells 2019 - “...bL21m AT4G30930 uL22m 1 AT1G52370 AT4G28360 uL23m AT4G39880 uL24m AT5G23535 bL25m 1 AT4G23620 AT5G66860 bL27m AT2G16930 bL28m AT4G31460 uL29m AT1G07830 uL30m AT5G55140 bL31m 1 AT5G55125 AT1G27435 bL33m AT5G18790 bL36m AT5G20180 mL40 AT4G05400 mL41 1 AT5G40080 AT5G39800 mL43 AT3G59650 mL46 AT1G14620 mL53 AT5G39600 mL54 AT3G01740 mL101 (rPPR4...”
- Detection of allele-specific methylation through a generalized heterogeneous epigenome model
Peng, Bioinformatics (Oxford, England) 2012 - “...AT1G59670 2 7089119 7089281 21 AT2G16380 3'UTR + 2 7340522 7340662 23 + AT2TE29970 < AT2G16930 2 14386759 14387012 23 + > AT2G34060 > AT2G34070 3 12092053 12092151 20 + AT3TE50300 3 16726743 16726938 29 < AT3G45570 AT3TE67795 + 4 2367251 2367352 20 + < AT4G04670...”
- Transposed genes in Arabidopsis are often associated with flanking repeats
Woodhouse, PLoS genetics 2010 - “...yes no AT2G26010 PR (pathogenesis-related) protein AT5G44430 69 direct yes within transposed sequence yes yes AT2G16930 ribosomal protein L27 family protein AT5G15220 72 direct yes RNA recognition motif (RRM)-containing protein no no AT3G10845 RNA recognition motif (RRM)-containing protein AT5G41690 79 direct yes hydroxyacylglutathione hydrolase no no...”
- “...could be found at the orthologous site in A. lyrata (AT2G34290, AT2G26010, AT3G10845, AT4G01640, and AT2G16930, Table 4 ). This A. lyrata sequence could well correspond to the recombination site for the insertion in A. thaliana . In addition, of these five genes, three (AT2G34290, AT2G26010,...”
D5EEJ4 Large ribosomal subunit protein bL27 from Aminobacterium colombiense (strain DSM 12261 / ALA-1)
59% identity, 87% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...drug design. Accession Codes: Proteins used in alignments: gp46, A4ZFB2; gp47, A4ZBF3; L27: Ac L27, D5EEJ4; Bb L27, O51721; Bp L27, D8IEK6; Br L27, B5RQB7; Bs L27, P05657; Cd L27, Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3;...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex.
Hotinger, Biochemistry 2022 - “...; Sm L27, Q8DUQ4 ; Sp L27, P66136 ; Fn L27, Q8REI3 ; Ac L27, D5EEJ4 ; Bb L27, O51721 ; Mp L27, P47476 ; Tm L27, Q9X1G7 . PDB entries: covalently bound Sa Prp, 7KLD ; unliganded Sa Prp, 4PEO ; Sm Prp, 2G0I ;...”
Sb09g025720 No description from Sorghum bicolor
56% identity, 57% coverage
B5YEQ2 Large ribosomal subunit protein bL27 from Dictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12)
52% identity, 96% coverage
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria.
Wall, Molecular microbiology 2015 - “...-YP_006934224, F. nucleatum -WP_005917003, C. aggregans -B8G6X2, L. ferroxidans -WP_014448398, T. lettingae -ABV34531, D. thermophilum -B5YEQ2, A. aeolicus -O67650, C. exile -YP_005473593, P. marinus -Q7V0C1, D. acetiphilus -ADD66838, P. mikurensis -BAM03335, N. gonorrhoeae - AAW90302, B. burgdorferi -WP_002656482, T. indicus -YP_004625725, B. fragilis -BAD47759, D. radiodurans...”
B2S3Y2 Large ribosomal subunit protein bL27 from Treponema pallidum subsp. pallidum (strain SS14)
58% identity, 91% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2; Uu L27, B5ZB18; Prp: Ac Prp, D5EEJ5; Bb Prp, A0A0H3C0W4; Bp Prp, D8IEK5; Br Prp, B5RQB6; Bs Prp, P26942; Cd Prp, A0A031WH70; Ct Prp, A0A4Q0V4F9; Ef Prp, Q3XX33; Ere Prp,...”
RL27_BACSU / P05657 Large ribosomal subunit protein bL27; 50S ribosomal protein L27; BL24; BL30 from Bacillus subtilis (strain 168) (see 2 papers)
BSU27940 50S ribosomal protein L27 from Bacillus subtilis subsp. subtilis str. 168
57% identity, 88% coverage
- function: Plays a role in sporulation at high temperatures.
subunit: Part of the 50S ribosomal subunit.
disruption phenotype: No effect on sporulation at 37 degrees Celsius, however sporulation decreases at 47 degrees Celsius. - The Blueprint of a Minimal Cell: MiniBacillus
Reuß, Microbiology and molecular biology reviews : MMBR 2016 - “...BSU16040 BSU28850 BSU27960 BSU01210 BSU01180 BSU01270 BSU27940 BSU15820 BSU01240 BSU01340 BSU37070 BSU15080 BSU24900 BSU00990 BSU41060 BSU28860 BSU01400...”
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...L27: Ac L27, D5EEJ4; Bb L27, O51721; Bp L27, D8IEK6; Br L27, B5RQB7; Bs L27, P05657; Cd L27, Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5;...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex.
Hotinger, Biochemistry 2022 - “...A4ZFB2 ; gp47, A4ZBF3 ; Sa L27, Q2FXT0 ; Ec L27, P0A7L8 ; Bs L27, P05657 ; Cd L27, Q18B22 ; Ef L27, A0A132ZFM0 ; Lr L27, K8QHR9 ; Sm L27, Q8DUQ4 ; Sp L27, P66136 ; Fn L27, Q8REI3 ; Ac L27, D5EEJ4 ; Bb...”
- Proteomics analyses of Bacillus subtilis after treatment with plumbagin, a plant-derived naphthoquinone
Reddy, Omics : a journal of integrative biology 2015 - “...protein L15 OS P20277 50S ribosomal protein L17 OS P05657 50S ribosomal protein L27 OS P42920 50S ribosomal protein L3 OS P19947 50S ribosomal protein L30 OS...”
- Interactions of an essential Bacillus subtilis GTPase, YsxC, with ribosomes
Wicker-Planquart, Journal of bacteriology 2008 - “...L23 (RL23_BACSU) Q06797 P42920 P42920 Q06797 P42923 P46898 P05657 P02394 P42924 762.4 92.4 722.9 542.3 401.4 69.6 320.5 170.8 35.2 24,776 22,669 22,669 24,776...”
8qcqW / P05657 8qcqW (see paper)
57% identity, 92% coverage
LSEI_1644 Ribosomal protein L27 from Lactobacillus casei ATCC 334
55% identity, 92% coverage
Q9CGL5 Large ribosomal subunit protein bL27 from Lactococcus lactis subsp. lactis (strain IL1403)
55% identity, 91% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136;...”
Q892N6 Large ribosomal subunit protein bL27 from Clostridium tetani (strain Massachusetts / E88)
53% identity, 88% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...O51721; Bp L27, D8IEK6; Br L27, B5RQB7; Bs L27, P05657; Cd L27, Q18B22; Ct L27, Q892N6; Ec L27, P0A7L8; Ef L27, A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476;...”
8fmwAY / O51721 8fmwAY (see paper)
63% identity, 84% coverage
B5ZB18 Large ribosomal subunit protein bL27 from Ureaplasma urealyticum serovar 10 (strain ATCC 33699 / Western)
54% identity, 85% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2; Uu L27, B5ZB18; Prp: Ac Prp, D5EEJ5; Bb Prp, A0A0H3C0W4; Bp Prp, D8IEK5; Br Prp, B5RQB6; Bs Prp, P26942; Cd Prp, A0A031WH70; Ct Prp, A0A4Q0V4F9; Ef Prp, Q3XX33; Ere Prp, R6TK63; Erh Prp,...”
W6AKZ4 Large ribosomal subunit protein bL27 from Spiroplasma mirum ATCC 29335
57% identity, 85% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2; Uu L27, B5ZB18; Prp: Ac Prp,...”
BC4436 LSU ribosomal protein L27P from Bacillus cereus ATCC 14579
54% identity, 93% coverage
Q74IL5 Large ribosomal subunit protein bL27 from Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
54% identity, 86% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...A0A132ZFM0; Ere L27, C4Z9Z8; Erh L27, E7FUU3; Fn L27, Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23;...”
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria
Wall, Molecular microbiology 2015 - “...-ADE56976, C. trachomatis -P66123, C. difficile -Q18B22, M. pneumoniae -P75458, E. rhusiopathiae -YP_004561011, L. johnsonii -Q74IL5, E. faecium -AFK58391, S. pneumoniae -Q04KI2, B. subtilis -CAB14754, S. aureus -NP_374758, H. pylori -YP_006934224, F. nucleatum -WP_005917003, C. aggregans -B8G6X2, L. ferroxidans -WP_014448398, T. lettingae -ABV34531, D. thermophilum -B5YEQ2,...”
LLNZ_07675 50S ribosomal protein L27 from Lactococcus cremoris subsp. cremoris NZ9000
LACR_1182 Ribosomal protein L27 from Lactococcus lactis subsp. cremoris SK11
53% identity, 91% coverage
EF0970 ribosomal protein L27 from Enterococcus faecalis V583
53% identity, 87% coverage
- Identification of surface proteins in Enterococcus faecalis V583
Bøhle, BMC genomics 2011 - “...anchor SP-II, LAA-CG 2 16.4 EF0916 50S ribosomal protein L20 Cytoplasmic (1) (1) 2 27.7 EF0970 e 50S ribosomal protein L27 Cytoplasmic 2 2 34.7 EF0991 Penicillin-binding protein C N-terminal anchor (1) 2 11.2 EF1033 Lipoamidase Cell wall anchored LPxTG SP-I, AQE-SI 2 2 4.7 EF1046...”
- “..."non-classical secretion". Analysis with SecP indicated that four of the proteins predicted to be cytoplasmic (EF0970, EF1523, EF2718 and EF_B0004) may follow non-classical secretion. PSORTb predicted EF_B0004 (TraC protein) to be a cell wall protein and Pfam gave a significant hit against "Bacterial extracellular solute-binding proteins,...”
- Transcriptional response of Enterococcus faecalis V583 to erythromycin
Aakra, Antimicrobial agents and chemotherapy 2005 - “...EF1310 EF1647 EF1700 EF2730 EF3073 EF0223 EF0224 EF0225 EF0226 EF0970 EF1694 EF2395 EF2397 EF2473 EF2474 EF2679 EF2731 EF3070 EF0285 EF1714 EF1718 EF2362 0 0 0...”
8p8wu / P75458 8p8wu (see paper)
60% identity, 69% coverage
P75458 Large ribosomal subunit protein bL27 from Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)
60% identity, 67% coverage
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria
Wall, Molecular microbiology 2015 - “...Prp homolog. Accession numbers: A. colombiense -ADE56976, C. trachomatis -P66123, C. difficile -Q18B22, M. pneumoniae -P75458, E. rhusiopathiae -YP_004561011, L. johnsonii -Q74IL5, E. faecium -AFK58391, S. pneumoniae -Q04KI2, B. subtilis -CAB14754, S. aureus -NP_374758, H. pylori -YP_006934224, F. nucleatum -WP_005917003, C. aggregans -B8G6X2, L. ferroxidans -WP_014448398,...”
Q8CS89 Large ribosomal subunit protein bL27 from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
Q5HNQ6 Large ribosomal subunit protein bL27 from Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
SERP1209 ribosomal protein L27 from Staphylococcus epidermidis RP62A
54% identity, 86% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2; Uu L27, B5ZB18;...”
- Mapping protein-exopolysaccharide binding interaction in Staphylococcus epidermidis biofilms by live cell proximity labeling.
Vo, bioRxiv : the preprint server for biology 2023 - “...enrichment Q5HP65 Probable elastin-binding protein EbpS Mem >19 Q5HM02 50S ribosomal protein L2 LRS >14 Q5HNQ6 50S ribosomal protein L27 LRS >18 Q5HRK7 30S ribosomal protein S12 SRS >16 Q5HM18 50S ribosomal protein L15 LRS >11 Q5HPP0 Aerobic glycerol-3-phosphate dehydrogenase Cyt >17 Q5HR42 DUF1361 domain-containing protein...”
- Concentration-Dependent Global Quantitative Proteome Response of Staphylococcus epidermidis RP62A Biofilms to Subinhibitory Tigecycline
Sung, Cells 2022 - “...III subunit delta 1000.00 1000.00 1000.00 SERP1193 hisS fig|176279.9.peg.1162 J Histidine--tRNA ligase 1000.00 1000.00 1000.00 SERP1209 rpmA fig|176279.9.peg.1178 J 50S ribosomal protein L27 5.89 4.72 1.09 SERP1211 rplU fig|176279.9.peg.1180 J 50S ribosomal protein L21 10.30 16.59 19.34 SERP0128 metG fig|176279.9.peg.120 J Methionine--tRNA ligase 0.00 1000.00 1000.00...”
MG_234 50S ribosomal protein L27 from Mycoplasma genitalium G37
P47476 Large ribosomal subunit protein bL27 from Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
52% identity, 82% coverage
- Transcriptional response to metal starvation in the emerging pathogen Mycoplasma genitalium is mediated by Fur-dependent and -independent regulatory pathways
Martínez-Torró, Emerging microbes & infections 2020 - “...several genes coding for two ribosomal proteins (MG_232 and MG_233), the ribosomal-processing cysteine protease Prp (MG_234), the apurinic endonuclease IV Nfo (MG_235) and the unknown protein MG_237 ( Figure 2 (B)). To assess the possible implication of the M. genitalium fur homologue in the regulation of...”
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...Q8REI3; Lb L27, B0SRT6; Lj L27, Q74IL5; Ll L27, Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7;...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex.
Hotinger, Biochemistry 2022 - “...; Fn L27, Q8REI3 ; Ac L27, D5EEJ4 ; Bb L27, O51721 ; Mp L27, P47476 ; Tm L27, Q9X1G7 . PDB entries: covalently bound Sa Prp, 7KLD ; unliganded Sa Prp, 4PEO ; Sm Prp, 2G0I ; Sp Prp, 2IDL ; Tm Prp, 1S1L ....”
RL27_STAA8 / Q2FXT0 Large ribosomal subunit protein bL27; 50S ribosomal protein L27 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 2 papers)
SA1471 50S ribosomal protein L27 from Staphylococcus aureus subsp. aureus N315
Q931Q3 Large ribosomal subunit protein bL27 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
SAOUHSC_01755 ribosomal protein L27 from Staphylococcus aureus subsp. aureus NCTC 8325
EKM74_RS01660 50S ribosomal protein L27 from Staphylococcus aureus
54% identity, 86% coverage
- subunit: Part of the 50S ribosomal subunit (PubMed:25388641). A mutant Prp protease unable to cleave bL27 copurifies with its substrate (PubMed:25388641).
disruption phenotype: Essential, it cannot be disrupted (PubMed:28187498). - Transcriptional profiles of the response of methicillin-resistant Staphylococcus aureus to pentacyclic triterpenoids
Chung, PloS one 2013 - “...rplX 50S ribosomal protein L24 9.7 Translation SA0459 rplY 50S ribosomal protein L25 5.4 Translation SA1471 rpmA 50S ribosomal protein L27 6.3 Translation SA1067 rpmB 50S ribosomal protein L28 6.3 Translation SA2039 rpmC 50S ribosomal protein L29 9.4 Translation SA2047 rplC 50S ribosomal protein L3 4.9...”
- Differential gene expression profiling of Staphylococcus aureus cultivated under biofilm and planktonic conditions
Resch, Applied and environmental microbiology 2005 - “...2.833 2.832 2.621 2.614 2.557 2.516 SA2016 SA2017 SA1471 SA2030 SA2045 SA1081 SA2029 SA0504 SA0495 SA1473 SA0354 SA0503 SA2031 SA0497 SA1116 SA2032 SA0496 3.324...”
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...Q9CGL5; Lr L27, K8QHR9; Mg L27, P47476; Mp L27, AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2;...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex
Hotinger, Biochemistry 2022 - “...bi2c00010_si_001.pdf Accession Codes Proteins used in alignments: gp46, A4ZFB2 ; gp47, A4ZBF3 ; Sa L27, Q2FXT0 ; Ec L27, P0A7L8 ; Bs L27, P05657 ; Cd L27, Q18B22 ; Ef L27, A0A132ZFM0 ; Lr L27, K8QHR9 ; Sm L27, Q8DUQ4 ; Sp L27, P66136 ; Fn...”
- Structural and Functional Dynamics of Staphylococcus aureus Biofilms and Biofilm Matrix Proteins on Different Clinical Materials
Hiltunen, Microorganisms 2019 - “...Q99S23 50S ribosomal protein L24 Q6GEJ4 50S ribosomal protein L25 Q99WA2 50S ribosomal protein L27 Q931Q3 50S ribosomal protein L28 Q6GHL1 50S ribosomal protein L29 Q6GEJ1 50S ribosomal protein L3 Q6GEI3 50S ribosomal protein L30 Q6GEK1 50S ribosomal protein L31 Q6GEV5 50S ribosomal protein L35 Q6GG26...”
- Low-level predation by lytic phage phiIPLA-RODI promotes biofilm formation and triggers the stringent response in Staphylococcus aureus
Fernández, Scientific reports 2017 - “...SAOUHSC_01715 udk Uridine kinase 2.38 SAOUHSC_01737 aspS AspartatetRNA ligase 2.95 SAOUHSC_01742 rsh GTP pyrophosphokinase 4.91 SAOUHSC_01755 rpmA 50S ribosomal protein L27 3.58 SAOUHSC_01767 valS ValinetRNA ligase 3.46 SAOUHSC_01771 hemL1 Glutamate-1-semialdehyde 2,1-aminomutase 1 2.90 SAOUHSC_01772 hemB Delta-aminolevulinic acid dehydratase 2.71 SAOUHSC_01776 hemA Glutamyl-tRNA reductase 2.06 SAOUHSC_01784 rplT...”
- Transcriptomic Analysis Revealed Antimicrobial Mechanisms of Lactobacillus rhamnosus SCB0119 against Escherichia coli and Staphylococcus aureus
Peng, International journal of molecular sciences 2022 - “...ribosomal protein L33 EKM74_RS01310 21.83 0.96 168.95 53.18 2.951911 rpsT ; 30S ribosomal protein S20 EKM74_RS01660 458.35 97.45 2756.92 263.1 2.588527 rpmA ; 50S ribosomal protein L27 EKM74_RS01670 102.05 29.64 4057 488.97 5.313122 rplU ; 50S ribosomal protein L21 EKM74_RS01855 19.42 10.05 621.08 94.23 4.999194 rplT...”
lp_1594 ribosomal protein L27 from Lactobacillus plantarum WCFS1
Q88WN3 Large ribosomal subunit protein bL27 from Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
51% identity, 92% coverage
- Transcriptomic Evidence of Molecular Mechanisms Underlying the Response of Lactobacillus Plantarum WCFS1 to Hydroxytyrosol
Reverón, Antioxidants (Basel, Switzerland) 2020 - “...rRNA genes ( lp_0011 [rpsR], lp_1063 [rplQ], lp_1078 [rpsI], lp_2125 [rpsO], lp_2126 [rpsT], lp_0543 [rpsS1], lp_1594 [rpl27], lp_1640 [rplS], lp_1517 [rplT],) and a ribosomal proteinserine acetyltransferase ( lp_2840 ) were all downregulated. In addition, other genes coding for translation related functions including lp_2378 or prfA (peptide...”
- Response of Lactobacillus plantarum WCFS1 to the Gram-Negative Pathogen-Associated Quorum Sensing Molecule N-3-Oxododecanoyl Homoserine Lactone
Spangler, Frontiers in microbiology 2019 - “...0.66 RL23_LACPL lp_1035 rplW 50S ribosomal protein L23 0.018 0.51 -0.51 0.49 0.16 1.16 RL27_LACPL lp_1594 rpmA 50S ribosomal protein L27 -0 -0.46 -0.23 1.9 1.7 0.19 RL28_LACPL lp_1624 rpmB 50S ribosomal protein L28 -0.18 0.016 -0.24 0.27 0.27 0.15 RL35_LACPL lp_1516 rpmI 50S ribosomal protein...”
- Screening of Lactiplantibacillus plantarum 67 with Strong Adhesion to Caco-2 Cells and the Effects of Protective Agents on Its Adhesion Ability during Vacuum Freeze Drying
Chen, Foods (Basel, Switzerland) 2023 - “...the PBS and the PAs, the expression of 50S ribosomal proteins (L7/L12, L27; Accession: Q88YW7, Q88WN3) of L. plantarum 67 was significantly downregulated, while the expressions of EF-G (Accession: Q88XY8, F9USR0) was significantly upregulated, compared with those without VFD ( p < 0.05; Table 2 )....”
- “...after VFD. Accession N/C P/C P/N FC p Value FC p Value FC p Value Q88WN3 0.67 0.0031 - - - - Q88YW7 - - 0.62 0.0002 - - F9URT0 0.61 0.0002 - - - - F9UR61 0.52 0.0002 0.62 0.0006 - - F9UTV9 0.52 <0.0001...”
- Proteomic Analysis Explores Interactions between Lactiplantibacillus plantarum and Saccharomyces cerevisiae during Sourdough Fermentation
Zhang, Microorganisms 2021 - “...Ribosomal Protein L31 up - - - A0A2S3U801 Ribosomal Protein L33 up - - - Q88WN3 Ribosomal Protein L27 up - - - A0A165VYQ7 Ribosomal Protein S1 up - - A0A3B6EL93 Ribosomal Protein L28 up - up - A0A3B6AUJ9 Ribosomal Protein S3 down up - -...”
SMU_849 50S ribosomal protein L27 from Streptococcus mutans UA159
Q8DUQ4 Large ribosomal subunit protein bL27 from Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
52% identity, 86% coverage
- Ribosomal-processing cysteine protease homolog modulates Streptococcus mutans glucan production and interkingdom interactions
Treerat, Journal of bacteriology 2024 (secret) - A five-species transcriptome array for oral mixed-biofilm studies
Redanz, PloS one 2011 - “...for pyruvat formiat lyase A, and several genes encoding ribosomal proteins like S7 (SMU_358), L27 (SMU_849), S1 (SMU_1200), S11 (SMU_2002) were found (Supporting Table S1 ). A total of 111 genes from the other species on the chip were found to react nonspecifically (refer to Table...”
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...AAB96157.1; Rt L27, A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2; Uu L27, B5ZB18; Prp: Ac Prp, D5EEJ5; Bb Prp,...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex
Hotinger, Biochemistry 2022 - “...; Cd L27, Q18B22 ; Ef L27, A0A132ZFM0 ; Lr L27, K8QHR9 ; Sm L27, Q8DUQ4 ; Sp L27, P66136 ; Fn L27, Q8REI3 ; Ac L27, D5EEJ4 ; Bb L27, O51721 ; Mp L27, P47476 ; Tm L27, Q9X1G7 . PDB entries: covalently bound Sa...”
SH1275 50S ribosomal protei L27 (BL30) from Staphylococcus haemolyticus JCSC1435
53% identity, 86% coverage
- In Silico Exploration of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>) Evolution Based on Phylogenetic Relationship of <i>ccrAB/C</i>
Wang, Microorganisms 2025 - “...ccrC - ccrC and a complete SCC mec structure; S. pseudintermedius K18PSP147 and S. haemolyticus SH1275 exhibit ccrAB - ccrC - ccrC and a complete SCC mec structure, whereas all four strains exhibit a loss of mecR1 and mecI in the mecA complex. S. aureus ER00951.3...”
- “...mec structures in staphylococci. S. haemolyticus PK-01, S. aureus MS4, S. pseudintermedius K18PSP147, S. haemolyticus SH1275, and S. aureus ER00951.3 have duplicate ccrAB/C complexes, while S. epidermidis B1230143 and S. epidermidis HD29-1 have incomplete SCCmec structures compared with regular SCC mec structures of S. aureus 04-02981...”
- Whole Genome Sequence Analysis of Two Oxacillin-Resistant and mecA-Positive Strains of Staphylococcus haemolyticus Isolated from Ear Swab Samples of Patients with Otitis Media
Liu, Infection and drug resistance 2024 - “...strains of S. haemolyticus were identified. Results The two strains of oxacillin-resistant S. haemolyticus (strain SH1275 and strain SH9361) both carried the genetic contexts of mecA with high similarity with the SCC mec type V(5C2&5) subtype c. Surprisingly, the chromosomal aminoglycoside resistance gene aac(6)-aph(2) harbored by...”
- “...visualize the sequence comparison. Nucleotide Sequence Accession Numbers The genome sequences of S. haemolyticus strain SH1275, which contained one chromosome and three plasmids, was submitted to GenBank under the accession numbers CP123979CP123982. The genome sequences of S. haemolyticus strain SH9361, which contained a chromosome and two...”
6xywAw / Q9ZVX0 6xywAw (see paper)
56% identity, 83% coverage
BMEI0202 LSU ribosomal protein L27P from Brucella melitensis 16M
61% identity, 74% coverage
A8F8P7 Large ribosomal subunit protein bL27 from Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO)
53% identity, 96% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis.
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2; Uu L27, B5ZB18; Prp: Ac Prp, D5EEJ5; Bb Prp, A0A0H3C0W4; Bp Prp, D8IEK5; Br Prp, B5RQB6; Bs Prp, P26942; Cd Prp,...”
MHJ_0128 50S ribosomal protein L27 from Mycoplasma hyopneumoniae J
52% identity, 96% coverage
Q71ZD0 Large ribosomal subunit protein bL27 from Listeria monocytogenes serotype 4b (strain F2365)
lmo1540 ribosomal protein L27 from Listeria monocytogenes EGD-e
52% identity, 93% coverage
- Proteomic Exploration of Listeria monocytogenes for the Purpose of Vaccine Designing Using a Reverse Vaccinology Approach
Srivastava, International journal of peptide research and therapeutics 2021 - “...0.925 Non-allergen 143 Q71ZJ5 0.952 Non-allergen 144 Q721N6 0.586 Non-allergen 145 Q71ZK1 1.532 Non-allergen 146 Q71ZD0 1.746 Non-allergen 147 Q71WF4 0.935 Non-allergen 148 Q71YL9 2.126 Non-allergen 149 Q71WG9 1.537 Non-allergen 150 Q71YK0 2.221 Non-allergen 151 Q71WI2 2.143 Non-allergen 152 Q71VQ6 1.957 Non-allergen 153 Q724G8 1.5 Non-allergen...”
- “...287.2 0.534 Antigen Q721N6 DRB1_1301 QMVQNRHGK 18 1.5447 Antigen Q71ZK1 DRB1_1301 KKSEAARKR 46.5 1.9356 Antigen Q71ZD0 DRB1_1301 MLKFDIQHF 45 1.2032 Antigen Q71WF4 DRB1_0101 LFNLRFQLA 1029 2.5288 Antigen Q71YL9 DRB1_1301 MAVKIRLKR 4.3 1.4155 Antigen DRB1_1301 AVKIRLKRI 55.1 1.4342 Antigen Q71YK0 DRB1_1301 RKSRSGNKR 40.5 2.7338 Antigen Q71WI2 DRB1_1301...”
- Protein level identification of the Listeria monocytogenes sigma H, sigma L, and sigma C regulons
Mujahid, BMC microbiology 2013 - “...strain, but were not identified as positively regulated by any of the alternative factors include Lmo1540, Lmo2610, Lmo1422, Lmo1421, Lmo1602, Lmo1426, Lmo1428, Lmo2205, Lmo2398, Lmo1601, Lmo0554, Lmo1634, Lmo0110, Lmo2558, Lmo0783, Lmo0134, and Lmo0098. Table 4 Proteins found to be differentially regulated by at least two of...”
- Listeria monocytogenes PrsA2 is required for virulence factor secretion and bacterial viability within the host cell cytosol
Alonzo, Infection and immunity 2010 - “...IspB Cell surface and cell wall metabolism lmo1540 lmo2505 lmo2504 Transport/binding proteins and lipoproteins lmo2416 Function or functional class P45 No....”
P66136 Large ribosomal subunit protein bL27 from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
51% identity, 88% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2; Uu L27, B5ZB18; Prp: Ac Prp, D5EEJ5; Bb Prp, A0A0H3C0W4; Bp Prp, D8IEK5; Br Prp,...”
- Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus: In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex
Hotinger, Biochemistry 2022 - “...; Ef L27, A0A132ZFM0 ; Lr L27, K8QHR9 ; Sm L27, Q8DUQ4 ; Sp L27, P66136 ; Fn L27, Q8REI3 ; Ac L27, D5EEJ4 ; Bb L27, O51721 ; Mp L27, P47476 ; Tm L27, Q9X1G7 . PDB entries: covalently bound Sa Prp, 7KLD ; unliganded...”
RT0737 50S ribosomal protein L27 from Rickettsia typhi str. wilmington
51% identity, 91% coverage
- GroEL is an immunodominant surface-exposed antigen of Rickettsia typhi
Rauch, PloS one 2021 - “...(RT0652), S16 (RT0869) and S7 (RT0120) and the 50S ribosomal proteins L7/L12 (RT0128) and L27 (RT0737), the ribosome recycling factor (RT0143) and the aspartyl/glutamyl-tRNA (Asn/Gln) amidotransferase subunit C (GatC, RT0142). One downregulated protein, HIT-like protein (RP317), might be involved in gene regulation by binding to small...”
F2QE23 Large ribosomal subunit protein bL27 from Streptococcus oralis (strain Uo5)
Q04KI2 Large ribosomal subunit protein bL27 from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
SPD_0991 ribosomal protein L27 from Streptococcus pneumoniae D39
51% identity, 86% coverage
- Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis
Hotinger, Antibiotics (Basel, Switzerland) 2022 - “...A5KLI2; Sa L27, Q2FXT0; Se L27, Q8CS89; Smi L27, W6AKZ4; Smu L27, Q8DUQ4; So L27, F2QE23; Spn L27, P66136; Spo L27, A0A2P6FBS6; Tl L27, A8F8P7; Tm L27, Q9X1G7; Tn L27, ADA67440.1; Tp L27, B2S3Y2; Uu L27, B5ZB18; Prp: Ac Prp, D5EEJ5; Bb Prp, A0A0H3C0W4; Bp Prp,...”
- Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria
Wall, Molecular microbiology 2015 - “...-Q18B22, M. pneumoniae -P75458, E. rhusiopathiae -YP_004561011, L. johnsonii -Q74IL5, E. faecium -AFK58391, S. pneumoniae -Q04KI2, B. subtilis -CAB14754, S. aureus -NP_374758, H. pylori -YP_006934224, F. nucleatum -WP_005917003, C. aggregans -B8G6X2, L. ferroxidans -WP_014448398, T. lettingae -ABV34531, D. thermophilum -B5YEQ2, A. aeolicus -O67650, C. exile -YP_005473593,...”
- The Rgg1518 transcriptional regulator is a necessary facet of sugar metabolism and virulence in Streptococcus pneumoniae
Shlla, Molecular microbiology 2021 - “...FeS assembly SPD_0905- SPD_0913 2.4266 Genetic information processing SPD_0942- SPD_0951 2.062.27 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase SPD_0989- SPD_0991 3.623.83 Protein synthesis SPD_1050- SPD_1053 3.464.73 Tagatose pathway, galactose catabolism SPD_1344-SPD_1349 2.042.88 acetyltransferase, GNAT family protein synthesis SPD_1473- SPD_1480 2.635.48 Cell division SPD_1512- SPD_1517 2.649.48 Membrane protein synthesis SPD_1667- SPD_1671...”
MGA_1292 50S ribosomal protein L27 from Mycoplasma gallisepticum str. R(low)
51% identity, 84% coverage
7mt2W / P9WHB3 7mt2W (see paper)
56% identity, 87% coverage
SSA_1062 50S ribosomal protein L27, putative from Streptococcus sanguinis SK36
51% identity, 86% coverage
- Involvement of signal peptidase I in Streptococcus sanguinis biofilm formation
Aynapudi, Microbiology (Reading, England) 2017 - “...4.98 22.09 l -lactate dehydrogenase Yes SSA_0176 5.07 21.1 DNA-directed RNA polymerase subunit beta No SSA_1062 5.75 11.69 50S ribosomal protein L27 No SSA_0688 5.77 32.78 2,3-bisphosphoglycerate-dep phosphoglycerate mutase No SSA_0859 7.75 62.77 Triosephosphate isomerase No SSA_0813 9.7 11.04 Thioredoxin reductase No SSA_0772 9.91 75.4 PTS...”
A8INR7 Uncharacterized protein from Chlamydomonas reinhardtii
54% identity, 42% coverage
6o8wX / A0A1B4XMB1 6o8wX (see paper)
50% identity, 85% coverage
5myjBZ / A2RLA2 of 70S ribosome from Lactococcus lactis (see paper)
52% identity, 84% coverage
9c4gv / A0A2B7IGT1 Cutibacterium acnes 50s ribosomal subunit with clindamycin bound (see paper)
58% identity, 87% coverage
5nrgT / Q2FXT0 The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with rb02 (see paper)
54% identity, 80% coverage
8uu4Y / A0A660JMC7 8uu4Y (see paper)
49% identity, 84% coverage
RM02_YEAST / P12687 Large ribosomal subunit protein bL27m; 54S ribosomal protein L2, mitochondrial; YMR6; YmL2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
NP_014393 mitochondrial 54S ribosomal protein YmL2 from Saccharomyces cerevisiae S288C
YNL005C Mitochondrial ribosomal protein of the large subunit from Saccharomyces cerevisiae
49% identity, 18% coverage
- function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
subunit: Component of the mitochondrial large ribosomal subunit (mt- LSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins. - The N-terminal region of yeast mitoribosomal Mrp7/bL27m protein serves to optimize translation of nascent chains competent for OXPHOS complex assembly.
Anderson, FEBS letters 2023 (PubMed)- GeneRIF: The N-terminal region of yeast mitoribosomal Mrp7/bL27m protein serves to optimize translation of nascent chains competent for OXPHOS complex assembly.
- The mitospecific domain of Mrp7 (bL27) supports mitochondrial translation during fermentation and is required for effective adaptation to respiration.
Anderson, Molecular biology of the cell 2022 - GeneRIF: The mitospecific domain of Mrp7 (bL27) supports mitochondrial translation during fermentation and is required for effective adaptation to respiration.
- Plus ça change - evolutionary sequence divergence predicts protein subcellular localization signals
Fukasawa, BMC genomics 2014 - “...is cleaved by the protease m-AAA [ 62 , 63 ] instead of MPP. Mrp7 (P12687) is a similar case. Like MrpL32, Mrp7 is also a component of a large ribosomal subunit and is not predicted to have an MTS by TargetP, Predator, nor by our...”
- Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal proteins
Neuberger, Genome biology 2004 - “...development); precursor of lysosomal bovine cathepsin D (P80209); and a mitochondrial ribosomal protein from yeast (P12687). We also examined the carboxyl terminus of a mouse dihydrofolate reductase construct with an added SKL peptide, which has been shown not to be imported into yeast peroxisomes [ 16...”
- “...that functions in the formation of pigments such as melanins. Yeast 60S ribosomal protein L2 (P12687), or MRP7, is a component of the large subunit of the mitochondrial ribosome. Green fluorescent protein (GFP) was appended to the amino terminus of each of the selected proteins. It...”
- Mitochondrial ribosomal proteins (MRPs) of yeast
Graack, The Biochemical journal 1998 - “...number Chromosomal gene location Total Signal peptide Daa P12687 S54026 P36517 S54533 SC8337 P22353 P31334 Z71560 Z74250 Q02204 S50921 S72159 14L 13R 12R 4R...”
- Mitochondria, Peroxisomes and Beyond-How Dual Targeting Regulates Organelle Tethering
Freitag, Contact (Thousand Oaks (Ventura County, Calif.)) 2024 - “...PTC5 YOR090C Type 2C protein phosphatase Vgtle et al., 2012; Stehlik et al., 2020 MRP7 YNL005C Mitochondrial ribosomal protein Fearon and Mason, 1988; Box et al., 2017 TES1 YJR019C Peroxisomal acyl-CoA thioesterase Jones et al., 1999 MSS2 YDL107W Inner membrane protein of mitochondria Simon et al.,...”
- Systematic analysis of nuclear gene function in respiratory growth and expression of the mitochondrial genome in S. cerevisiae
Stenger, Microbial cell (Graz, Austria) 2020 - “...RSM7 YJR113C MRP4 YHL004W MRPS8 YMR158W SLM5 YCR024C MRP51 YPL118W MRS1 YIR021W SLS1 YLR139C MRP7 YNL005C MRX14 YDR115W SWS2 YNL081C MRPL10 YNL284C MSD1 YPL104W TUF1 YOR187W MRPL11 YDL202W MSE1 YOL033W MRPL13 YKR006C MSF1 YPR047W Mitochondrial transcription MSS116 YDR194C MTF2 YDL044C MTF1 YMR228W RPO41 YFL036W Respiratory chain...”
- “...RSM18 YER050C MRP4 YHL004W MRPL51 YPR100W RSM19 YNR037C MRP51 YPL118W MRPS12 YNR036C RSM23 YGL129C MRP7 YNL005C MRPS16 YPL013C RSM24 YDR175C MRPL10 YNL284C MRPS35 YGR165W RSM27 YGR215W MRPL11 YDL202W MSK1 YNL073W SWS2 YNL081C MRPL16 YBL038W MST1 YKL194C Respiratory chain components and assembly factors COX5A YNL052W Mitochondrial fusion...”
- Regulatory and evolutionary adaptation of yeast to acute lethal ethanol stress
Yang, PloS one 2020 - “...PET117 YER058W 5.86 electron transport chain ASF1 YJL115W 4.20 nucleosome assembly factor, stress response MRP7 YNL005C 4.02 mitochondrial ribosomal large subunit VPS24 YKL041W 3.81 vacuolar protein sorting CTR1 YPR124W 3.74 copper transporter REG1 YDR028C 3.49 protein phosphatase regulator GAT2 YMR136W 3.34 transcription factor DEPLETED Gene Name...”
- Pex35 is a regulator of peroxisome abundance
Yofe, Journal of cell science 2017 - “...0.14 0.54 11 YGL143C Mrf1 0.49 0.28 0.57 12 YBR251W Mrps5 0.13 0.07 0.57 13 YNL005C Mrp7 0.30 0.17 0.58 14 YHR147C Mrpl6 0.19 0.11 0.61 15 YER185W Pug1 1.51 0.94 0.62 16 YGL076C Rpl7a 0.49 0.31 0.63 17 YMR142C Rpl13b 0.49 0.32 0.65 18 YPR099C...”
- RSC Chromatin-Remodeling Complex Is Important for Mitochondrial Function in Saccharomyces cerevisiae
Imamura, PloS one 2015 - “...peptide, regulates translation of the CPA1 mRNA Mitochondria Mitochondrial translation YLR069C MEF1 Mitochondrial Elongation Factor YNL005C MRP7 Mitochondrial Ribosomal Protein YLR439W MRPL4 Mitochondrial Ribosomal Protein, Large subunit YBR282W MRPL27 Mitochondrial Ribosomal Protein, Large subunit YCR003W MRPL32 Mitochondrial Ribosomal Protein, Large subunit YPR100W MRPL51 Mitochondrial Ribosomal Protein,...”
- Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method
Xie, Proceedings of the National Academy of Sciences of the United States of America 2005 - “...11 12 13 14 Control YOR200W YOR199W YLR288C YNL005C YNR041C YMR071C YOR187W YPR124W YJR104C YMR066W YDL198C YDL181W YMR038C YGR076C YNL135C Gene name MEC3 MRP7...”
HPODL_00194 54S ribosomal protein L2, mitochondrial from Ogataea parapolymorpha DL-1
41% identity, 23% coverage
5mrcR / P12687 of the yeast mitochondrial ribosome - Class A (see paper)
49% identity, 18% coverage
6z1pAA / I7M068 6z1pAA (see paper)
44% identity, 41% coverage
TGME49_293600 ribosomal protein RPL27 from Toxoplasma gondii ME49
50% identity, 17% coverage
- The Expressed MicroRNA-mRNA Interactions of Toxoplasma gondii
Acar, Frontiers in microbiology 2017 - “...contained gene names in form of a combination of strain and accession number (e.g., gene TGME49_293600 ). To make annotations clearer, unigene identifiers were used where possible. In cases where a protein is synthesized from multiple genes, gene accessions (e.g., 293600) were added to the end...”
RM02_NEUCR / Q1K730 Large ribosomal subunit protein bL27m from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 2 papers)
46% identity, 14% coverage
- function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
subunit: Component of the mitochondrial large ribosomal subunit (mt- LSU). Mature N.crassa 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 16S ribosomal RNA (16S mt-rRNA) and 32 different proteins. The 54S large subunit contains a 23S rRNA (23S mt-rRNA) and 42 different proteins.
6yweR / Q8X0Q2 structure of the mitoribosome from Neurospora crassa in the P/E tRNA bound state (see paper)
46% identity, 24% coverage
7pktu / A0A2K3E880 7pktu (see paper)
48% identity, 46% coverage
4ce40 / A0A4X1U0F6 39s large subunit of the porcine mitochondrial ribosome (see paper)
39% identity, 84% coverage
RM27_BOVIN / Q32PC3 Large ribosomal subunit protein bL27m; 39S ribosomal protein L27, mitochondrial; L27mt; MRP-L27 from Bos taurus (Bovine) (see 2 papers)
45% identity, 46% coverage
- subunit: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.
RM27_HUMAN / Q9P0M9 Large ribosomal subunit protein bL27m; 39S ribosomal protein L27, mitochondrial; L27mt; MRP-L27 from Homo sapiens (Human) (see 5 papers)
NP_057588 large ribosomal subunit protein bL27m from Homo sapiens
46% identity, 46% coverage
- subunit: Component of the mitochondrial large ribosomal subunit (mt- LSU) (PubMed:25278503, PubMed:25838379, PubMed:28892042, PubMed:35177605). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.
- MRPL27 contributes to unfavorable overall survival and disease-free survival from cholangiocarcinoma patients.
Zhuang, International journal of medical sciences 2021 - GeneRIF: MRPL27 contributes to unfavorable overall survival and disease-free survival from cholangiocarcinoma patients.
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson, PloS one 2010 - GeneRIF: Observational study of gene-disease association. (HuGE Navigator)
- Secretory Carrier Membrane Protein 3 Interacts with 3A Viral Protein of Enterovirus and Participates in Viral Replication.
Lu, Microbiology spectrum 2021 - “...4 15.41 Q96A35 MRPL24 39S Ribosomal protein L24, mitochondrial 24.9 241.8 3 3 5 16.67 Q9P0M9 MRPL27 39S Ribosomal protein L27, mitochondrial 16.1 69.2 2 2 3 16.89 Q13084 MRPL28 39S Ribosomal protein L28, mitochondrial 30.1 80.3 2 2 3 12.89 Q9BYD3 MRPL4 39S Ribosomal protein...”
- Proteomics Reveals that Methylmalonyl-CoA Mutase Modulates Cell Architecture and Increases Susceptibility to Stress
Costanzo, International journal of molecular sciences 2020 - “...3.6 Q8IYQ7 Threonine synthase-like 1 THNSL1 UP 3.7 Q9BSF4 Uncharacterized protein C19orf52 C19orf52 UP 4.0 Q9P0M9 39S ribosomal protein L27, mitochondrial MRPL27 UP 4.5 P00395 Cytochrome c oxidase subunit 1 COX1 UP 5.7 ijms-21-04998-t003_Table 3 Table 3 Dysregulated proteins in MUT-KO involved in cell architecture modification....”
- Effects of thyroid hormone on mitochondria and metabolism of human preimplantation embryos.
Noli, Stem cells (Dayton, Ohio) 2020 - “...P30405 Involved in regulation of the mitochondrial permeability transition pore MRPL27, Mitochondrial ribosomal protein L27, Q9P0M9 Mitoribosome subunit involved in translating mitochondrial mRNA MRPL51, Mitochondrial ribosomal protein L51, Q4U2R6 Mitoribosome subunit involved in translating mitochondrial mRNA HSPE1, Heat shock 10kDa protein 1, P61604 Mitochondrial protein biogenesis...”
- Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2.
Guo, Molecular bioSystems 2011 - “...protein L35 (RPL35) 1 P42766 N/C mitochondrial ribosomal proteins mitochondrial ribosomal protein L27 (MRPL27) 2 Q9P0M9 Mt. mitochondrial ribosomal protein S18A (MRPS18A) 1 Q9NVS2 Mt. Non-ribosomal proteins Putative RNA-binding protein 15 2 Q96T37 N Probable rRNA-processing protein EBP2 1 Q99848 N Heterogeneous nuclear ribonucleoprotein A1 1...”
- A universal strategy for proteomic studies of SUMO and other ubiquitin-like modifiers.
Rosas-Acosta, Molecular & cellular proteomics : MCP 2005
5aj4B0 / A0A4X1U0F6 of the 55S mammalian mitoribosome. (see paper)
46% identity, 54% coverage
8anyW / Q9P0M9 8anyW (see paper)
46% identity, 57% coverage
8a22Au 8a22Au (see paper)
41% identity, 51% coverage
RM27_MOUSE / Q99N92 Large ribosomal subunit protein bL27m; 39S ribosomal protein L27, mitochondrial; L27mt; MRP-L27 from Mus musculus (Mouse) (see paper)
43% identity, 46% coverage
- subunit: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.
- Extensive mitochondrial proteome disturbance occurs during the early stages of acute myocardial ischemia.
Wang, Experimental and therapeutic medicine 2022 - “...12A, regulatory, non-sarcomeric Up Q8BGU5 CCNY Cyclin-Y Up Q8VCI5 PEX19 Peroxisomal biogenesis factor 19 Up Q99N92 MRPL27 39S ribosomal protein L27, mitochondrial Up Q9D666 SUN1 SUN domain-containing protein 1 Up Q9DAW9 CNN3 Calponin-3 Up Q9JIK5 DDX21 Nucleolar RNA helicase 2 Up Q9JKY7 CYP2D22 Cytochrome P450 CYP2D22...”
For advice on how to use these tools together, see
Interactive tools for functional annotation of bacterial genomes.
The PaperBLAST database links 793,807 different protein sequences to 1,259,118 scientific articles. Searches against EuropePMC were last performed on March 13 2025.
PaperBLAST builds a database of protein sequences that are linked
to scientific articles. These links come from automated text searches
against the articles in EuropePMC
and from manually-curated information from GeneRIF, UniProtKB/Swiss-Prot,
BRENDA,
CAZy (as made available by dbCAN),
BioLiP,
CharProtDB,
MetaCyc,
EcoCyc,
TCDB,
REBASE,
the Fitness Browser,
and a subset of the European Nucleotide Archive with the /experiment tag.
Given this database and a protein sequence query,
PaperBLAST uses protein-protein BLAST
to find similar sequences with E < 0.001.
To build the database, we query EuropePMC with locus tags, with RefSeq protein
identifiers, and with UniProt
accessions. We obtain the locus tags from RefSeq or from MicrobesOnline. We use
queries of the form "locus_tag AND genus_name" to try to ensure that
the paper is actually discussing that gene. Because EuropePMC indexes
most recent biomedical papers, even if they are not open access, some
of the links may be to papers that you cannot read or that our
computers cannot read. We query each of these identifiers that
appears in the open access part of EuropePMC, as well as every locus
tag that appears in the 500 most-referenced genomes, so that a gene
may appear in the PaperBLAST results even though none of the papers
that mention it are open access. We also incorporate text-mined links
from EuropePMC that link open access articles to UniProt or RefSeq
identifiers. (This yields some additional links because EuropePMC
uses different heuristics for their text mining than we do.)
For every article that mentions a locus tag, a RefSeq protein
identifier, or a UniProt accession, we try to select one or two
snippets of text that refer to the protein. If we cannot get access to
the full text, we try to select a snippet from the abstract, but
unfortunately, unique identifiers such as locus tags are rarely
provided in abstracts.
PaperBLAST also incorporates manually-curated protein functions:
- Proteins from NCBI's RefSeq are included if a
GeneRIF
entry links the gene to an article in
PubMed®.
GeneRIF also provides a short summary of the article's claim about the
protein, which is shown instead of a snippet.
- Proteins from Swiss-Prot (the curated part of UniProt)
are included if the curators
identified experimental evidence for the protein's function (evidence
code ECO:0000269). For these proteins, the fields of the Swiss-Prot entry that
describe the protein's function are shown (with bold headings).
- Proteins from BRENDA,
a curated database of enzymes, are included if they are linked to a paper in PubMed
and their full sequence is known.
- Every protein from the non-redundant subset of
BioLiP,
a database
of ligand-binding sites and catalytic residues in protein structures, is included. Since BioLiP itself
does not include descriptions of the proteins, those are taken from the
Protein Data Bank.
Descriptions from PDB rely on the original submitter of the
structure and cannot be updated by others, so they may be less reliable.
(For SitesBLAST and Sites on a Tree, we use a larger subset of BioLiP so that every
ligand is represented among a group of structures with similar sequences, but for
PaperBLAST, we use the non-redundant set provided by BioLiP.)
- Every protein from EcoCyc, a curated
database of the proteins in Escherichia coli K-12, is included, regardless
of whether they are characterized or not.
- Proteins from the MetaCyc metabolic pathway database
are included if they are linked to a paper in PubMed and their full sequence is known.
- Proteins from the Transport Classification Database (TCDB)
are included if they have known substrate(s), have reference(s),
and are not described as uncharacterized or putative.
(Some of the references are not visible on the PaperBLAST web site.)
- Every protein from CharProtDB,
a database of experimentally characterized protein annotations, is included.
- Proteins from the CAZy database of carbohydrate-active enzymes
are included if they are associated with an Enzyme Classification number.
Even though CAZy does not provide links from individual protein sequences to papers,
these should all be experimentally-characterized proteins.
- Proteins from the REBASE database
of restriction enzymes are included if they have known specificity.
- Every protein with an evidence-based reannotation (based on mutant phenotypes)
in the Fitness Browser is included.
- Sequence-specific transcription factors (including sigma factors and DNA-binding response regulators)
with experimentally-determined DNA binding sites from the
PRODORIC database of gene regulation in prokaryotes.
- Putative transcription factors from RegPrecise
that have manually-curated predictions for their binding sites. These predictions are based on
conserved putative regulatory sites across genomes that contain similar transcription factors,
so PaperBLAST clusters the TFs at 70% identity and retains just one member of each cluster.
- Coding sequence (CDS) features from the
European Nucleotide Archive (ENA)
are included if the /experiment tag is set (implying that there is experimental evidence for the annotation),
the nucleotide entry links to paper(s) in PubMed,
and the nucleotide entry is from the STD data class
(implying that these are targeted annotated sequences, not from shotgun sequencing).
Also, to filter out genes whose transcription or translation was detected, but whose function
was not studied, nucleotide entries or papers with more than 25 such proteins are excluded.
Descriptions from ENA rely on the original submitter of the
sequence and cannot be updated by others, so they may be less reliable.
Except for GeneRIF and ENA,
the curated entries include a short curated
description of the protein's function.
For entries from BioLiP, the protein's function may not be known beyond binding to the ligand.
Many of these entries also link to articles in PubMed.
For more information see the
PaperBLAST paper (mSystems 2017)
or the code.
You can download PaperBLAST's database here.
Changes to PaperBLAST since the paper was written:
- November 2023: incorporated PRODORIC and RegPrecise. Many PRODORIC entries were not linked to a protein sequence (no UniProt identifier), so we added this information.
- February 2023: BioLiP changed their download format. PaperBLAST now includes their non-redundant subset. SitesBLAST and Sites on a Tree use a larger non-redundant subset that ensures that every ligand is represented within each cluster. This should ensure that every binding site is represented.
- June 2022: incorporated some coding sequences from ENA with the /experiment tag.
- March 2022: incorporated BioLiP.
- April 2020: incorporated TCDB.
- April 2019: EuropePMC now returns table entries in their search results. This has expanded PaperBLAST's database, but most of the new entries are of low relevance, and the resulting snippets are often just lists of locus tags with annotations.
- February 2018: the alignment page reports the conservation of the hit's functional sites (if available from from Swiss-Prot or UniProt)
- January 2018: incorporated BRENDA.
- December 2017: incorporated MetaCyc, CharProtDB, CAZy, REBASE, and the reannotations from the Fitness Browser.
- September 2017: EuropePMC no longer returns some table entries in their search results. This has shrunk PaperBLAST's database, but has also reduced the number of low-relevance hits.
Many of these changes are described in Interactive tools for functional annotation of bacterial genomes.
PaperBLAST cannot provide snippets for many of the papers that are
published in non-open-access journals. This limitation applies even if
the paper is marked as "free" on the publisher's web site and is
available in PubmedCentral or EuropePMC. If a journal that you publish
in is marked as "secret," please consider publishing elsewhere.
Many important articles are missing from PaperBLAST, either because
the article's full text is not in EuropePMC (as for many older
articles), or because the paper does not mention a protein identifier such as a locus tag, or because of PaperBLAST's heuristics. If you notice an
article that characterizes a protein's function but is missing from
PaperBLAST, please notify the curators at UniProt
or add an entry to GeneRIF.
Entries in either of these databases will eventually be incorporated
into PaperBLAST. Note that to add an entry to UniProt, you will need
to find the UniProt identifier for the protein. If the protein is not
already in UniProt, you can ask them to create an entry. To add an
entry to GeneRIF, you will need an NCBI Gene identifier, but
unfortunately many prokaryotic proteins in RefSeq do not have
corresponding Gene identifers.
References
PaperBLAST: Text-mining papers for information about homologs.
M. N. Price and A. P. Arkin (2017). mSystems, 10.1128/mSystems.00039-17.
Europe PMC in 2017.
M. Levchenko et al (2017). Nucleic Acids Research, 10.1093/nar/gkx1005.
Gene indexing: characterization and analysis of NLM's GeneRIFs.
J. A. Mitchell et al (2003). AMIA Annu Symp Proc 2003:460-464.
UniProt: the universal protein knowledgebase.
The UniProt Consortium (2016). Nucleic Acids Research, 10.1093/nar/gkw1099.
BRENDA in 2017: new perspectives and new tools in BRENDA.
S. Placzek et al (2017). Nucleic Acids Research, 10.1093/nar/gkw952.
The EcoCyc database: reflecting new knowledge about Escherichia coli K-12.
I. M. Keeseler et al (2016). Nucleic Acids Research, 10.1093/nar/gkw1003.
The MetaCyc database of metabolic pathways and enzymes.
R. Caspi et al (2018). Nucleic Acids Research, 10.1093/nar/gkx935.
CharProtDB: a database of experimentally characterized protein annotations.
R. Madupu et al (2012). Nucleic Acids Research, 10.1093/nar/gkr1133.
The carbohydrate-active enzymes database (CAZy) in 2013.
V. Lombard et al (2014). Nucleic Acids Research, 10.1093/nar/gkt1178.
The Transporter Classification Database (TCDB): recent advances
M. H. Saier, Jr. et al (2016). Nucleic Acids Research, 10.1093/nar/gkv1103.
REBASE - a database for DNA restriction and modification: enzymes, genes and genomes.
R. J. Roberts et al (2015). Nucleic Acids Research, 10.1093/nar/gku1046.
Deep annotation of protein function across diverse bacteria from mutant phenotypes.
M. N. Price et al (2016). bioRxiv, 10.1101/072470.
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory