PaperBLAST – Find papers about a protein or its homologs

 

Papers vs. PDB: Well-studied proteins that lack structural information

Papers vs. PDB shows proteins that are mentioned in at least 10 papers yet are not similar to any protein of known structure.

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Protein that Lacks Structural Information Region #Papers
1. Breast cancer type 1 susceptibility protein; EC 2.3.2.27; RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1 111:1643/1863 2327
  Homo sapiens (Human) PFam BRCT_assoc 61% dis. no TMH
2. Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4 1:550/920 1809
  Homo sapiens (Human) PFam Androgen_recep 63% dis. no TMH
3. myc proto-oncogene protein 81:364/454 1462
  Homo sapiens PFam Myc_N 57% dis. no TMH
4. microtubule-associated protein tau isoform 6 1:586/776 1215
  Homo sapiens no PFam hits 92% dis. no TMH
5. stromal cell-derived factor 1 isoform 5 precursor 39:103/103 1053
  Homo sapiens no PFam hits 36% dis. no TMH
6. CD44 antigen; CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD44 antigen 179:671/742 931
  Homo sapiens (Human) no PFam hits 71% dis. partly
7. nuclear factor erythroid 2-related factor 2 isoform 5 1:371/532 906
  Homo sapiens no PFam hits 51% dis. no TMH
8. Natriuretic peptides B; Gamma-brain natriuretic peptide 1:101/134 902
  Homo sapiens (Human) no PFam hits 50% dis. no TMH
9. vascular endothelial growth factor A isoform 3 1:203/324 821
  Mus musculus no PFam hits 66% dis. no TMH
10. osteopontin isoform 5 All 327 815
  Homo sapiens PFam Osteopontin 68% dis. no TMH
11. forkhead box protein P3 isoform X4 1:262/504 785
  Homo sapiens no PFam hits 60% dis. no TMH
12. Glucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1 1:407/777 757
  Homo sapiens (Human) PFam GCR 54% dis. no TMH
13. Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39 1:248/331 729
  Homo sapiens (Human) PFam Jun 59% dis. no TMH
14. Transcription factor Sp1 1:596/785 717
  Homo sapiens (Human) no PFam hits 59% dis. no TMH
15. Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; Nuclear factor, erythroid derived 2, like 2 52:436/597 710
  Mus musculus (Mouse) no PFam hits 56% dis. no TMH
16. Endothelin-1; Preproendothelin-1; PPET1 76:212/212 706
  Homo sapiens (Human) no PFam hits 51% dis. no TMH
17. tumor necrosis factor ligand superfamily member 10 isoform 2 All 101 705
  Homo sapiens no PFam hits 14% dis. partly
18. Caveolin-1 All 178 694
  Homo sapiens (Human) PFam Caveolin 11% dis. partly
19. apolipoprotein B-100 precursor All 4563 627
  Homo sapiens PFams Vitellogenin_N, DUF1943, DUF1081, ... 20% dis. βB MP
20. Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3 1:552/933 625
  Homo sapiens (Human) PFam Prog_receptor 62% dis. no TMH
21. UDP-glucuronosyltransferase 1-1; UDPGT 1-1; UGT1*1; UGT1-01; UGT1.1; EC 2.4.1.17; Bilirubin-specific UDPGT isozyme 1; hUG-BR1; UDP-glucuronosyltransferase 1-A; UGT-1A; UGT1A; UDP-glucuronosyltransferase 1A1 1:277/533 609
  Homo sapiens (Human) PFam UDPGT 6% dis. partly
22. antigen KI-67 isoform 2 187:2896/2896 583
  Homo sapiens PFam K167R 73% dis. no TMH
23. transcription factor 7-like 2 isoform X14 63:386/631 538
  Homo sapiens PFam CTNNB1_binding 54% dis. no TMH
24. ALK tyrosine kinase receptor; EC 2.7.10.1; Anaplastic lymphoma kinase; CD246 antigen 1:1070/1620 522
  Homo sapiens (Human) PFams MAM, Gly_rich 30% dis. partly
25. Wilms tumor protein isoform A 1:345/497 514
  Homo sapiens PFam WT1 60% dis. no TMH
26. vascular endothelial growth factor A isoform 1 1:204/393 505
  Rattus norvegicus no PFam hits 66% dis. no TMH
27. myc proto-oncogene protein isoform a 81:364/454 484
  Mus musculus PFam Myc_N 57% dis. no TMH
28. peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X4 208:648/786 476
  Homo sapiens no PFam hits 62% dis. no TMH
29. NACHT, LRR and PYD domains-containing protein 3; Cold autoinflammatory syndrome 1 protein homolog; Cryopyrin; Mast cell maturation-associated-inducible protein 1; PYRIN-containing APAF1-like protein 1 109:702/1033 474
  Mus musculus (Mouse) PFams NACHT, FISNA 13% dis. no TMH
30. NACHT, LRR and PYD domains-containing protein 3 isoform c 113:696/979 448
  Homo sapiens PFams NACHT, FISNA 13% dis. no TMH
31. Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma 271:655/655 440
  Homo sapiens (Human) PFams FOXO_KIX_bdg, FOXO-TAD 64% dis. no TMH
32. Transcription factor SOX-2 120:317/317 440
  Homo sapiens (Human) PFam SOXp 54% dis. no TMH
33. prominin-1 isoform X9 All 825 440
  Homo sapiens PFam Prominin 15% dis. partly
34. Twist-related protein 1; Class A basic helix-loop-helix protein 38; bHLHa38; H-twist 1:107/202 439
  Homo sapiens (Human) no PFam hits 94% dis. no TMH
35. Tumor necrosis factor ligand superfamily member 11; Osteoclast differentiation factor; ODF; Osteoprotegerin ligand; OPGL; Receptor activator of nuclear factor kappa-B ligand; RANKL; TNF-related activation-induced cytokine; TRANCE; CD254 antigen 1:160/316 435
  Mus musculus (Mouse) no PFam hits 43% dis. partly
36. peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1 232:672/810 419
  Mus musculus no PFam hits 59% dis. no TMH
37. Caveolin-1 All 178 415
  Mus musculus (Mouse) PFam Caveolin 12% dis. partly
38. Aryl hydrocarbon receptor; Ah receptor; AhR; Class E basic helix-loop-helix protein 76; bHLHe76 381:848/848 408
  Homo sapiens (Human) no PFam hits 48% dis. no TMH
39. Clusterin; Aging-associated gene 4 protein; Apolipoprotein J; Apo-J; Complement cytolysis inhibitor; CLI; Complement-associated protein SP-40,40; Ku70-binding protein 1; NA1/NA2; Testosterone-repressed prostate message 2; TRPM-2 All 449 407
  Homo sapiens (Human) PFam Clusterin 32% dis. no TMH
40. Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma 268:652/652 381
  Mus musculus (Mouse) PFams FOXO_KIX_bdg, FOXO-TAD 62% dis. no TMH
41. Insulin receptor substrate 1; IRS-1 268:1242/1242 373
  Homo sapiens (Human) no PFam hits 73% dis. no TMH
42. Endothelial PAS domain-containing protein 1; EPAS-1; Basic-helix-loop-helix-PAS protein MOP2; Class E basic helix-loop-helix protein 73; bHLHe73; HIF-1-alpha-like factor; HLF; Hypoxia-inducible factor 2-alpha; HIF-2-alpha; HIF2-alpha; Member of PAS protein 2; PAS domain-containing protein 2 362:819/870 371
  Homo sapiens (Human) PFam HIF-1 56% dis. no TMH
43. Apolipoprotein A-V; Apo-AV; ApoA-V; Apolipoprotein A5; Regeneration-associated protein 3 All 366 370
  Homo sapiens (Human) PFam Apolipoprotein 44% dis. no TMH
44. Hepcidin; Liver-expressed antimicrobial peptide 1; LEAP-1; Putative liver tumor regressor; PLTR 1:59/84 370
  Homo sapiens (Human) no PFam hits 22% dis. 1 TMH
45. A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X2 556:1297/1297 369
  Homo sapiens PFam TSP_1 28% dis. no TMH
46. pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1b 226:624/624 364
  Homo sapiens PFam Neuregulin 69% dis. partly
47. vitamin K epoxide reductase complex subunit 1 isoform 2 precursor All 92 359
  Homo sapiens PFam VKOR 4% dis. partly
48. Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124 antigen 229:825/825 357
  Homo sapiens (Human) no PFam hits 50% dis. partly
49. tumor necrosis factor receptor superfamily member 1B isoform X2 220:484/484 357
  Homo sapiens no PFam hits 62% dis. partly
50. CCAAT/enhancer-binding protein alpha; C/EBP alpha 1:272/358 348
  Homo sapiens (Human) no PFam hits 75% dis. no TMH
51. Early growth response protein 1; EGR-1; AT225; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24 1:292/543 347
  Homo sapiens (Human) PFam DUF3446 67% dis. no TMH
52. X protein 1:110/154 340
  Hepatitis B virus PFam X 30% dis. no TMH
53. Neuroendocrine secretory protein 55; NESP55 All 245 338
  Homo sapiens (Human) PFam NESP55 76% dis. no TMH
54. Transcription factor AP-1; AH119; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; Jun A 1:251/334 332
  Mus musculus (Mouse) PFam Jun 58% dis. no TMH
55. Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK 1:177/266 332
  Homo sapiens (Human) PFam Dickkopf_N 27% dis. partly
56. bcl-2-like protein 11 isoform 4 All 135 331
  Homo sapiens PFam Bim_N 74% dis. no TMH
57. osteopontin isoform 1 All 311 330
  Mus musculus PFam Osteopontin 71% dis. no TMH
58. nibrin isoform 2 245:672/672 329
  Homo sapiens PFam Nbs1_C 61% dis. no TMH
59. hepatocyte nuclear factor 1-alpha isoform X1 293:662/662 329
  Homo sapiens PFams HNF-1B_C, HNF-1A_C 64% dis. no TMH
60. cDNA FLJ77127, highly similar to Homo sapiens forkhead box M1 (FOXM1), transcript variant 3, mRNA 345:747/747 322
  Homo sapiens no PFam hits 56% dis. no TMH
61. endothelin-1 isoform X1 76:202/202 319
  Rattus norvegicus no PFam hits 39% dis. no TMH
62. calcitonin isoform CT preproprotein 1:84/141 318
  Homo sapiens PFam Calc_CGRP_IAPP 37% dis. no TMH
63. Tumor suppressor ARF; Alternative reading frame; ARF; Cyclin-dependent kinase inhibitor 2A; p19ARF 38:169/169 311
  Mus musculus (Mouse) no PFam hits 33% dis. partly
64. Bone morphogenetic protein 4; BMP-4; Bone morphogenetic protein 2B; BMP-2B 1:211/408 307
  Homo sapiens (Human) PFam TGFb_propeptide 41% dis. no TMH
65. Guanine nucleotide exchange C9orf72 All 481 306
  Homo sapiens (Human) PFam C9orf72-like 15% dis. no TMH
66. CCAAT/enhancer-binding protein beta isoform b 1:189/275 298
  Mus musculus no PFam hits 41% dis. no TMH
67. Pentraxin-related protein PTX3 All 381 293
  Homo sapiens PFams Pentaxin, Laminin_G_3 26% dis. no TMH
68. N-myc proto-oncogene protein; Class E basic helix-loop-helix protein 37; bHLHe37 90:376/464 293
  Homo sapiens (Human) PFam Myc_N 74% dis. no TMH
69. Krueppel-like factor 4 isoform 2 1:376/479 292
  Homo sapiens no PFam hits 63% dis. no TMH
70. aryl hydrocarbon receptor isoform 2 268:688/688 289
  Mus musculus no PFam hits 44% dis. no TMH
71. DNA repair protein complementing XP-C cells; Xeroderma pigmentosum group C-complementing protein; p125 157:940/940 288
  Homo sapiens (Human) PFams BHD_3, Rad4, BHD_1, ... 41% dis. no TMH
72. sequestosome-1 isoform 2 88:301/356 285
  Homo sapiens no PFam hits 78% dis. no TMH
73. Filaggrin 103:4061/4061 285
  Homo sapiens (Human) PFam Filaggrin 94% dis. no TMH
74. Bone morphogenetic protein 4; BMP-4; Bone morphogenetic protein 2B; BMP-2B 1:279/408 284
  Mus musculus (Mouse) PFam TGFb_propeptide 42% dis. no TMH
75. CCAAT/enhancer-binding protein beta; C/EBP beta; Liver activator protein; LAP; Liver-enriched inhibitory protein; LIP; Nuclear factor NF-IL6; Transcription factor 5; TCF-5 1:258/345 283
  Homo sapiens (Human) no PFam hits 57% dis. no TMH
76. muellerian-inhibiting factor precursor 1:456/560 278
  Homo sapiens PFam AMH_N 43% dis. no TMH
77. trans-acting T-cell-specific transcription factor GATA-3 isoform X1 1:251/444 278
  Homo sapiens no PFam hits 60% dis. no TMH
78. tumor necrosis factor ligand superfamily member 6 isoform 2 All 131 277
  Mus musculus no PFam hits 43% dis. partly
79. Transcription factor SOX-9 182:509/509 277
  Homo sapiens (Human) no PFam hits 81% dis. no TMH
80. Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4 1:529/899 276
  Mus musculus (Mouse) PFam Androgen_recep 66% dis. no TMH
81. Appetite-regulating hormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide 1:75/117 275
  Rattus norvegicus (Rat) PFam Motilin_ghrelin 53% dis. no TMH
82. Cytochrome b-245 light chain; Cytochrome b(558) alpha chain; Cytochrome b558 subunit alpha; Neutrophil cytochrome b 22 kDa polypeptide; Superoxide-generating NADPH oxidase light chain subunit; p22 phagocyte B-cytochrome; p22-phox; p22phox All 195 273
  Homo sapiens (Human) PFam Cytochrom_B558a 29% dis. partly
83. Hematopoietic progenitor cell antigen CD34; CD34 antigen All 385 273
  Homo sapiens (Human) PFam CD34_antigen 47% dis. partly
84. Growth/differentiation factor 15 1:196/308 273
  Homo sapiens no PFam hits 45% dis. no TMH
85. High mobility group protein HMGI-C; High mobility group AT-hook protein 2 All 109 269
  Homo sapiens (Human) PFam AT_hook 97% dis. no TMH
86. transcription factor SOX-2 122:319/319 268
  Rattus norvegicus PFam SOXp 53% dis. no TMH
87. Sterol regulatory element-binding protein 1; SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1 401:1147/1147 268
  Homo sapiens (Human) no PFam hits 30% dis. no TMH
88. Solute carrier organic anion transporter family member 1B1; Liver-specific organic anion transporter 1; LST-1; OATP-C; Sodium-independent organic anion-transporting polypeptide 2; OATP-2; Solute carrier family 21 member 6 All 691 265
  Homo sapiens (Human) PFams OATP, MFS_1, Kazal_2 9% dis. partly
89. Mucin-5AC; MUC-5AC; Gastric mucin; Lewis B blood group antigen; LeB; Major airway glycoprotein; Mucin-5 subtype AC, tracheobronchial; Tracheobronchial mucin; TBM 900:5545/5654 263
  Homo sapiens (Human) PFams Mucin2_WxxW, VWD, C8 54% dis. no TMH
90. microtubule-associated protein tau isoform X5 1:577/767 263
  Mus musculus no PFam hits 90% dis. no TMH
91. zinc finger protein GLI1 isoform 2 299:978/978 260
  Homo sapiens no PFam hits 70% dis. no TMH
92. dystrophin isoform X2 453:3037/3695 258
  Homo sapiens PFam Spectrin 36% dis. no TMH
93. homeobox protein CDX-2 isoform X1 1:166/321 255
  Homo sapiens PFam Caudal_act 54% dis. no TMH
94. Cytochrome b-245 heavy chain; EC 1.-.-.-; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome 1:303/570 254
  Homo sapiens (Human) PFam Ferric_reduct 4% dis. partly
95. tumor necrosis factor receptor superfamily member 10B isoform 2 precursor 191:411/411 250
  Homo sapiens PFam Death 40% dis. no TMH
96. sex hormone-binding globulin isoform 5 161:344/344 248
  Homo sapiens no PFam hits 31% dis. no TMH
97. syndecan-1 precursor All 310 242
  Homo sapiens PFam Syndecan 72% dis. partly
98. Cytochrome b-245 heavy chain; EC 1.-.-.-; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; Neutrophil cytochrome b 91 kDa polypeptide; gp91-1; gp91-phox; p22 phagocyte B-cytochrome 1:303/570 242
  Mus musculus (Mouse) PFam Ferric_reduct 5% dis. partly
99. tuberin isoform X4 1:1588/1879 242
  Homo sapiens PFams Tuberin, DUF3384 31% dis. no TMH
100. Heat shock factor protein 1; HSF 1; Heat shock transcription factor 1; HSTF 1 121:529/529 240
  Homo sapiens (Human) PFam Vert_HS_TF 57% dis. no TMH

Only the 100 most-cited proteins were shown.


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Developed by Morgan Price, Arkin lab, LBL