GapMind for Amino acid biosynthesis

 

Potential Gaps in Amino acid biosynthesis

Found 204 low-confidence and 573 medium-confidence steps on the best paths for 18 pathways x 206 genomes. 68 of 777 gaps have been classified.

Pathway Step Organism Best candidate 2nd candidate Class of gap
arg argA: N-acylglutamate synthase Steroidobacter denitrificans DSM 18526 ACG33_RS14135 ACG33_RS14155  
arg argC: N-acylglutamylphosphate reductase Ferroglobus placidus DSM 10642 FERP_RS04630  
arg argC: N-acylglutamylphosphate reductase Methanococcus aeolicus Nankai-3 MAEO_RS06695  
arg argC: N-acylglutamylphosphate reductase Methanococcus maripaludis C5 MMARC5_RS07930 MMARC5_RS00960  
arg argC: N-acylglutamylphosphate reductase Methanothermobacter thermautotrophicus str. Delta H MTH_RS03985  
arg argC: N-acylglutamylphosphate reductase Nocardiopsis lucentensis DSM 44048 D471_RS0118275 spurious
arg argD: N-acetylornithine aminotransferase Arcobacter nitrofigilis DSM 7299 ARNIT_RS13880 ARNIT_RS07040  
arg argD: N-acetylornithine aminotransferase Chlorobium phaeobacteroides BS1 Cphamn1_0638 Cphamn1_0202  
arg argD: N-acetylornithine aminotransferase Methanosarcina acetivorans C2A MA_RS00620 MA_RS15010  
arg argD: N-acetylornithine aminotransferase Methanosarcina mazei Go1 MM_RS07280 MM_RS00255  
arg argD: N-acetylornithine aminotransferase Prosthecochloris aestuarii DSM 271 PAES_RS02955 PAES_RS00970  
arg argD: N-acetylornithine aminotransferase Steroidobacter denitrificans DSM 18526 ACG33_RS14145 ACG33_RS02865  
arg argD: N-acetylornithine aminotransferase Sulfurimonas denitrificans DSM 1251 SUDEN_RS06570 SUDEN_RS06750  
arg argE: N-acetylornithine deacetylase Steroidobacter denitrificans DSM 18526  
arg argF': acetylornithine transcarbamoylase Steroidobacter denitrificans DSM 18526 ACG33_RS14150  
arg argG: arginosuccinate synthetase Dechloromonas agitata is5 spurious
arg argG: arginosuccinate synthetase Derxia gummosa DSM 723 spurious
arg argH: argininosuccinate lyase Beijerinckia indica subsp. indica ATCC 9039 spurious
arg argH: argininosuccinate lyase Pyrolobus fumarii 1A PYRFU_RS03710 PYRFU_RS04310  
arg argJ: ornithine acetyltransferase Thermocrinis albus DSM 14484 THAL_RS04200  
arg argX: glutamate--LysW ligase Halococcus hamelinensis 100A6 C447_RS04730  
arg argX: glutamate--LysW ligase Haloferax volcanii DS2 C498_RS17890  
arg carA: carbamoyl phosphate synthase subunit alpha Steroidobacter denitrificans DSM 18526 spurious
arg carA: carbamoyl phosphate synthase subunit alpha Thermus aquaticus YT-1 spurious
arg carB: carbamoyl phosphate synthase subunit beta Methanothermobacter thermautotrophicus str. Delta H spurious
arg lysJ: [LysW]-glutamate-semialdehyde aminotransferase Haloferax volcanii DS2 C498_RS17875 C498_RS02300  
arg lysK: [LysW]-ornithine hydrolase Halococcus hamelinensis 100A6 C447_RS16710 C447_RS04710  
arg lysK: [LysW]-ornithine hydrolase Haloferax volcanii DS2 C498_RS12835 C498_RS17870  
arg lysK: [LysW]-ornithine hydrolase Nitrosopumilus maritimus SCM1 NMAR_RS06940  
arg lysK: [LysW]-ornithine hydrolase Pyrolobus fumarii 1A PYRFU_RS08530  
arg lysK: [LysW]-ornithine hydrolase Thermus aquaticus YT-1 BVI061214_RS03250 BVI061214_RS04800  
arg lysZ: [LysW]-glutamate kinase Halococcus hamelinensis 100A6 C447_RS04720  
arg lysZ: [LysW]-glutamate kinase Haloferax volcanii DS2 C498_RS17880  
arg lysZ: [LysW]-glutamate kinase Thermus aquaticus YT-1 BVI061214_RS04210 BVI061214_RS02685  
asn aspS2: aspartyl-tRNA(Asp/Asn) synthetase Acidimicrobium ferrooxidans DSM 10331 AFER_RS02725 AFER_RS09855  
asn aspS2: aspartyl-tRNA(Asp/Asn) synthetase Frankia alni ACN14a FRAAL_RS05245  
asn aspS2: aspartyl-tRNA(Asp/Asn) synthetase Nitriliruptor alkaliphilus DSM 45188 NITAL_RS16550  
asn aspS2: aspartyl-tRNA(Asp/Asn) synthetase Phaeacidiphilus oryzae TH49 BS73_RS08565 BS73_RS27475  
asn aspS2: aspartyl-tRNA(Asp/Asn) synthetase Pyrolobus fumarii 1A PYRFU_RS03160  
asn aspS2: aspartyl-tRNA(Asp/Asn) synthetase Thermomonospora curvata DSM 43183 TCUR_RS10525 TCUR_RS10510  
asn gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C Methanococcus aeolicus Nankai-3 MAEO_RS04560  
asn gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C Methanothermobacter thermautotrophicus str. Delta H MTH_RS01920  
asn gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C Nitrosopumilus maritimus SCM1  
chorismate aroA: 3-phosphoshikimate 1-carboxyvinyltransferase Pyrolobus fumarii 1A PYRFU_RS00635  
chorismate aroA: 3-phosphoshikimate 1-carboxyvinyltransferase Thiohalomonas denitrificans HLD2 spurious
chorismate aroA: 3-phosphoshikimate 1-carboxyvinyltransferase Thiohalospira halophila DSM 15071 HL 3 spurious
chorismate aroA': 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase Derxia gummosa DSM 723 spurious
chorismate aroA': 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase Desulfotalea psychrophila LSv54 DP_RS12420 spurious
chorismate aroB: 3-dehydroquinate synthase Acidimicrobium ferrooxidans DSM 10331 AFER_RS08885  
chorismate aroB: 3-dehydroquinate synthase Pyrolobus fumarii 1A PYRFU_RS07225  
chorismate aroB: 3-dehydroquinate synthase Thermus aquaticus YT-1 BVI061214_RS06225  
chorismate aroB': dehydroquinate synthase II Derxia gummosa DSM 723 spurious
chorismate aroB': dehydroquinate synthase II Desulfotalea psychrophila LSv54 spurious
chorismate aroC: chorismate synthase Chlorobaculum parvum NCIB 8327 spurious
chorismate aroC: chorismate synthase Phaeacidiphilus oryzae TH49 spurious
chorismate aroC: chorismate synthase Shewanella oneidensis MR-1 SO3078.2  
chorismate aroC: chorismate synthase Thioalkalivibrio halophilus HL17 spurious
chorismate aroD: 3-dehydroquinate dehydratase Frankia alni ACN14a FRAAL_RS03895  
chorismate aroD: 3-dehydroquinate dehydratase Halococcus hamelinensis 100A6 C447_RS11795 spurious
chorismate aroD: 3-dehydroquinate dehydratase Haloferax volcanii DS2 C498_RS15190 C498_RS15185  
chorismate aroD: 3-dehydroquinate dehydratase Haloglycomyces albus DSM 45210 spurious
chorismate aroD: 3-dehydroquinate dehydratase Methanospirillum lacunae Ki8-1 DK846_RS00875 DK846_RS01955  
chorismate aroD: 3-dehydroquinate dehydratase Pyrolobus fumarii 1A PYRFU_RS04235 PYRFU_RS03905  
chorismate aroE: shikimate dehydrogenase Methanospirillum lacunae Ki8-1 DK846_RS01955  
chorismate aroE: shikimate dehydrogenase Methanothermobacter thermautotrophicus str. Delta H MTH_RS04785 spurious
chorismate aroE: shikimate dehydrogenase Nitriliruptor alkaliphilus DSM 45188 NITAL_RS16585  
chorismate aroE: shikimate dehydrogenase Pelobacter propionicus DSM 2379 PPRO_RS11690  
chorismate aroE: shikimate dehydrogenase Prosthecochloris aestuarii DSM 271 PAES_RS08265  
chorismate aroL: shikimate kinase Acidimicrobium ferrooxidans DSM 10331 AFER_RS01155 AFER_RS08325  
chorismate aroL: shikimate kinase Alkalihalobacterium alkalinitrilicum DSM 22532 BK574_RS11810 BK574_RS17815  
chorismate aroL: shikimate kinase Anaerobutyricum hallii DSM 3353 EUBHAL_RS06870 EUBHAL_RS01140  
chorismate aroL: shikimate kinase Aquimarina longa SW024 N456_RS19870  
chorismate aroL: shikimate kinase Arcobacter nitrofigilis DSM 7299 ARNIT_RS03210  
chorismate aroL: shikimate kinase Azospirillum brasilense Sp245 AZOBR_RS17125 AZOBR_RS18985 spurious
chorismate aroL: shikimate kinase Calditerrivibrio nitroreducens DSM 19672 CALNI_RS01115  
chorismate aroL: shikimate kinase Caminibacter mediatlanticus TB-2 CMTB2_RS02520  
chorismate aroL: shikimate kinase Chlorobaculum parvum NCIB 8327 CPAR_RS03890  
chorismate aroL: shikimate kinase Chlorobium limicola DSM 245 CLIM_RS04760 CLIM_RS00440  
chorismate aroL: shikimate kinase Chlorobium phaeobacteroides BS1 Cphamn1_0960 Cphamn1_0100  
chorismate aroL: shikimate kinase Clostridium acetobutylicum ATCC 824 CA_RS04790 CA_RS09580  
chorismate aroL: shikimate kinase Clostridium kluyveri DSM 555 CKL_RS03880  
chorismate aroL: shikimate kinase Clostridium tyrobutyricum FAM22553 spurious
chorismate aroL: shikimate kinase Dehalococcoides mccartyi 195 DET_RS02515  
chorismate aroL: shikimate kinase Desulfarculus baarsii DSM 2075 DEBA_RS16080 DEBA_RS09240  
chorismate aroL: shikimate kinase Desulfatiglans anilini DSM 4660 H567_RS22310 H567_RS0114935  
chorismate aroL: shikimate kinase Desulfogranum mediterraneum DSM 13871 G494_RS0104115 G494_RS0102320  
chorismate aroL: shikimate kinase Desulforamulus ruminis DSM 2154 DESRU_RS15745 DESRU_RS14945  
chorismate aroL: shikimate kinase Desulfuromonas acetexigens DSM 1397 BQ4888_RS02755 BQ4888_RS16740  
chorismate aroL: shikimate kinase Desulfuromusa kysingii DSM 7343 BLU87_RS06245 BLU87_RS02125  
chorismate aroL: shikimate kinase Hippea alviniae EP5-r G415_RS0103525 G415_RS0104365  
chorismate aroL: shikimate kinase Leptospirillum ferrooxidans C2-3 LFE_RS07665  
chorismate aroL: shikimate kinase Malonomonas rubra DSM 5091 BUB13_RS16435 BUB13_RS10355  
chorismate aroL: shikimate kinase Methanospirillum lacunae Ki8-1 DK846_RS01955 DK846_RS15050  
chorismate aroL: shikimate kinase Nitratifractor salsuginis DSM 16511 NITSA_RS09825 NITSA_RS08560  
chorismate aroL: shikimate kinase Nitratiruptor tergarcus DSM 16512 B8779_RS08595  
chorismate aroL: shikimate kinase Prosthecochloris aestuarii DSM 271 PAES_RS07580 PAES_RS00600  
chorismate aroL: shikimate kinase Roseburia faecis M72 M72_RS11675 M72_RS15390  
chorismate aroL: shikimate kinase Sulfuricurvum kujiense DSM 16994 SULKU_RS03215  
chorismate aroL: shikimate kinase Sulfurimonas denitrificans DSM 1251 SUDEN_RS02585  
chorismate aroL: shikimate kinase Thermoanaerobacter kivui LKT-1 TKV_RS05740  
chorismate aroL: shikimate kinase Thermocrinis albus DSM 14484 THAL_RS02745  
chorismate aroL: shikimate kinase Thermovibrio ammonificans HB-1 THEAM_RS06475 THEAM_RS01420  
chorismate aroL: shikimate kinase Trichlorobacter lovleyi SZ GLOV_RS07865 GLOV_RS15295  
chorismate asp-kinase: aspartate kinase Halococcus hamelinensis 100A6 C447_RS02970  
chorismate asp-kinase: aspartate kinase Haloferax volcanii DS2 C498_RS17705  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Archaeoglobus veneficus SNP6 ARCVE_RS04465 ARCVE_RS05825  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Desulfatiglans anilini DSM 4660 H567_RS22300 H567_RS0100630  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Desulfovibrio oxyclinae DSM 11498 B149_RS0107855 B149_RS0103015  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Desulfurobacterium atlanticum DSM 15668 CHB58_RS03905  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Ferroglobus placidus DSM 10642 FERP_RS07635 FERP_RS02995  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Methanobacterium lacus AL-21 METBO_RS02970 METBO_RS06790  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Methanothermobacter thermautotrophicus str. Delta H MTH_RS08075 MTH_RS02685  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Nitrosopumilus maritimus SCM1 NMAR_RS05560 NMAR_RS02960  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Paucidesulfovibrio gracilis DSM 16080 B5D49_RS08675 B5D49_RS09460 spurious
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Persephonella marina EX-H1 PERMA_RS08670  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Sulfurihydrogenibium azorense Az-Fu1 SULAZ_RS03065  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Sulfurihydrogenibium subterraneum DSM 15120 Q385_RS0101975  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Thermocrinis albus DSM 14484 THAL_RS07745 THAL_RS02685  
chorismate fbp: 6-deoxy-5-ketofructose 1-phosphate synthase Thermovibrio ammonificans HB-1 THEAM_RS02275  
cys cysE: serine acetyltransferase Paucidesulfovibrio gracilis DSM 16080 B5D49_RS15105 spurious
cys cysK: O-acetylserine or O-succinylserine sulfhydrylase Caminibacter mediatlanticus TB-2 CMTB2_RS00355 CMTB2_RS05595  
cys PSSH: O-phosphoserine sulfhydrylase Halomonas desiderata SP1 BZY95_RS12545 BZY95_RS13365  
cys serC: 3-phosphoserine aminotransferase Desulfobacca acetoxidans DSM 11109 DESAC_RS06350  
cys serC: 3-phosphoserine aminotransferase Persephonella marina EX-H1 PERMA_RS01695  
cys serC: 3-phosphoserine aminotransferase Pyrolobus fumarii 1A PYRFU_RS03405  
cys serC: 3-phosphoserine aminotransferase Sulfurihydrogenibium azorense Az-Fu1 SULAZ_RS02850 spurious
cys serC: 3-phosphoserine aminotransferase Sulfurihydrogenibium subterraneum DSM 15120 Q385_RS0102205  
cys serC: 3-phosphoserine aminotransferase Thermocrinis albus DSM 14484 THAL_RS04470  
gln glnA: glutamine synthetase Clostridium kluyveri DSM 555 CKL_RS00630  
gln glnA: glutamine synthetase Clostridium tyrobutyricum FAM22553 PN53_RS15125  
gln glnA: glutamine synthetase Dehalococcoides mccartyi 195 DET_RS05810  
gln glnA: glutamine synthetase Desulfarculus baarsii DSM 2075 DEBA_RS05720  
gln glnA: glutamine synthetase Desulfatiglans anilini DSM 4660 H567_RS0111570  
gln glnA: glutamine synthetase Desulfobacca acetoxidans DSM 11109 DESAC_RS05150  
gln glnA: glutamine synthetase Desulfovibrio oxyclinae DSM 11498 B149_RS0106590  
gln glnA: glutamine synthetase Paucidesulfovibrio gracilis DSM 16080 B5D49_RS13465  
gln gltX: glutamyl-tRNA(Glx) synthetase Clostridium kluyveri DSM 555 CKL_RS07170  
gln gltX: glutamyl-tRNA(Glx) synthetase Dehalococcoides mccartyi 195 DET_RS07000  
gln gltX: glutamyl-tRNA(Glx) synthetase Desulfarculus baarsii DSM 2075 DEBA_RS00500  
gln gltX: glutamyl-tRNA(Glx) synthetase Desulfatiglans anilini DSM 4660 H567_RS0110855  
gln gltX: glutamyl-tRNA(Glx) synthetase Desulfobacca acetoxidans DSM 11109 DESAC_RS08375  
gln gltX: glutamyl-tRNA(Glx) synthetase Desulfovibrio oxyclinae DSM 11498 B149_RS0103595  
gln gltX: glutamyl-tRNA(Glx) synthetase Paucidesulfovibrio gracilis DSM 16080 B5D49_RS01925  
his hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase Acidimicrobium ferrooxidans DSM 10331 AFER_RS05670 AFER_RS05665  
his hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase Methanospirillum lacunae Ki8-1 DK846_RS02885 DK846_RS07815  
his hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase Pyrolobus fumarii 1A PYRFU_RS07130 PYRFU_RS07125  
his hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase Thiomicrospira pelophila DSM 1534 spurious
his hisC: histidinol-phosphate aminotransferase Frankia alni ACN14a FRAAL_RS21810 FRAAL_RS35345  
his hisC: histidinol-phosphate aminotransferase Nitriliruptor alkaliphilus DSM 45188 NITAL_RS18760 NITAL_RS15945  
his hisC: histidinol-phosphate aminotransferase Synechococcus elongatus PCC 7942 Synpcc7942_1030 Synpcc7942_1109  
his hisC: histidinol-phosphate aminotransferase Teredinibacter turnerae T7901 TERTU_RS04235 TERTU_RS05030  
his hisC: histidinol-phosphate aminotransferase Thermus aquaticus YT-1 BVI061214_RS06950 BVI061214_RS10030  
his hisD: histidinal/histidinol dehydrogenase Azospirillum brasilense Sp245 spurious
his hisD: histidinal/histidinol dehydrogenase Desulfoscipio geothermicus DSM 3669 spurious
his hisE: phosphoribosyl-AMP cyclohydrolase Anaerobutyricum hallii DSM 3353 EUBHAL_RS03360 spurious
his hisE: phosphoribosyl-AMP cyclohydrolase Pelobacter propionicus DSM 2379 PPRO_RS15095 spurious
his hisF: imidazole glycerol phosphate synthase, cyclase subunit Thiomicrospira pelophila DSM 1534 spurious
his hisG: ATP phosphoribosyltransferase Methylobacterium nodulans ORS 2060 spurious
his hisH: imidazole glycerol phosphate synthase, amidotransferase subunit Thiomicrospira pelophila DSM 1534 spurious
his hisI: phosphoribosyl-ATP pyrophosphatase Acidimicrobium ferrooxidans DSM 10331 AFER_RS05690 AFER_RS08245  
his hisI: phosphoribosyl-ATP pyrophosphatase Anaerobutyricum hallii DSM 3353 EUBHAL_RS03360 EUBHAL_RS01030  
his hisI: phosphoribosyl-ATP pyrophosphatase Chlorobaculum parvum NCIB 8327 CPAR_RS07305 CPAR_RS09930  
his hisI: phosphoribosyl-ATP pyrophosphatase Chlorobaculum tepidum TLS AYT24_RS02560 AYT24_RS09415  
his hisI: phosphoribosyl-ATP pyrophosphatase Chlorobium limicola DSM 245 CLIM_RS02615 CLIM_RS11925  
his hisI: phosphoribosyl-ATP pyrophosphatase Chlorobium phaeobacteroides BS1 Cphamn1_1819 Cphamn1_0246  
his hisI: phosphoribosyl-ATP pyrophosphatase Dehalococcoides mccartyi 195 DET_RS04400 DET_RS08360  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfacinum hydrothermale DSM 13146 B9A12_RS03080 B9A12_RS02075  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfacinum infernum DSM 9756 BUB04_RS00565 BUB04_RS02805  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfarculus baarsii DSM 2075 DEBA_RS04780 DEBA_RS06115  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfatibacillum aliphaticivorans DSM 15576 G491_RS0107675 G491_RS32330  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfatiglans anilini DSM 4660 H567_RS0118835 H567_RS0115195  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfobacca acetoxidans DSM 11109 DESAC_RS07050 DESAC_RS13025  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfobacter vibrioformis DSM 8776 Q366_RS09325 Q366_RS10585  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfogranum mediterraneum DSM 13871 G494_RS0117715 G494_RS0110315  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfoscipio geothermicus DSM 3669 BM299_RS07660  
his hisI: phosphoribosyl-ATP pyrophosphatase Desulfotalea psychrophila LSv54 DP_RS06475 DP_RS13395  
his hisI: phosphoribosyl-ATP pyrophosphatase Nitrosopumilus maritimus SCM1 NMAR_RS08345  
his hisI: phosphoribosyl-ATP pyrophosphatase Prosthecochloris aestuarii DSM 271 PAES_RS03450 PAES_RS01075  
his hisI: phosphoribosyl-ATP pyrophosphatase Thermodesulforhabdus norvegica DSM 9990 BM091_RS02930 BM091_RS07235  
his hisI: phosphoribosyl-ATP pyrophosphatase Thermomonospora curvata DSM 43183 TCUR_RS27545 TCUR_RS28280  
his hisN: histidinol-phosphate phosphatase Acidimicrobium ferrooxidans DSM 10331 AFER_RS01810 AFER_RS05680  
his hisN: histidinol-phosphate phosphatase Anaerobutyricum hallii DSM 3353 EUBHAL_RS05390 EUBHAL_RS12670  
his hisN: histidinol-phosphate phosphatase Archaeoglobus veneficus SNP6 ARCVE_RS08880  
his hisN: histidinol-phosphate phosphatase Arcobacter nitrofigilis DSM 7299 ARNIT_RS13180 ARNIT_RS09735  
his hisN: histidinol-phosphate phosphatase Calditerrivibrio nitroreducens DSM 19672 CALNI_RS09825  
his hisN: histidinol-phosphate phosphatase Carboxydothermus pertinax Ug1 cpu_RS01420 cpu_RS12565  
his hisN: histidinol-phosphate phosphatase Chlorobaculum parvum NCIB 8327 CPAR_RS03600 CPAR_RS02705  
his hisN: histidinol-phosphate phosphatase Clostridium acetobutylicum ATCC 824 CA_RS14050 CA_RS04990  
his hisN: histidinol-phosphate phosphatase Clostridium kluyveri DSM 555 CKL_RS01320 CKL_RS06425  
his hisN: histidinol-phosphate phosphatase Clostridium tyrobutyricum FAM22553 PN53_RS00720 PN53_RS00680  
his hisN: histidinol-phosphate phosphatase Dehalococcoides mccartyi 195 DET_RS04390 DET_RS01145  
his hisN: histidinol-phosphate phosphatase Denitrovibrio acetiphilus DSM 12809 DACET_RS14105 DACET_RS05830  
his hisN: histidinol-phosphate phosphatase Desulfacinum hydrothermale DSM 13146 B9A12_RS00860 B9A12_RS00755  
his hisN: histidinol-phosphate phosphatase Desulfacinum infernum DSM 9756 BUB04_RS09485 BUB04_RS14065  
his hisN: histidinol-phosphate phosphatase Desulfarculus baarsii DSM 2075 DEBA_RS07130 DEBA_RS04350  
his hisN: histidinol-phosphate phosphatase Desulfatibacillum aliphaticivorans DSM 15576 G491_RS30500 G491_RS0109105  
his hisN: histidinol-phosphate phosphatase Desulfitobacterium hafniense DCB-2 DHAF_RS20375 DHAF_RS07455  
his hisN: histidinol-phosphate phosphatase Desulfobacca acetoxidans DSM 11109 DESAC_RS14005 DESAC_RS09210  
his hisN: histidinol-phosphate phosphatase Desulfobacter vibrioformis DSM 8776 Q366_RS04490 Q366_RS03600 spurious
his hisN: histidinol-phosphate phosphatase Desulfogranum mediterraneum DSM 13871 G494_RS21305 G494_RS0111655 spurious
his hisN: histidinol-phosphate phosphatase Desulfoscipio geothermicus DSM 3669 BM299_RS15995 BM299_RS02165  
his hisN: histidinol-phosphate phosphatase Desulfotalea psychrophila LSv54 DP_RS06735  
his hisN: histidinol-phosphate phosphatase Desulfovibrio oxyclinae DSM 11498 B149_RS0104715 B149_RS0111010  
his hisN: histidinol-phosphate phosphatase Desulfovibrio vulgaris Hildenborough JW710 DVU2490 DVU1040  
his hisN: histidinol-phosphate phosphatase Desulfovibrio vulgaris Miyazaki F DvMF_0940 DvMF_3122  
his hisN: histidinol-phosphate phosphatase Desulfurobacterium atlanticum DSM 15668 CHB58_RS01910 CHB58_RS02010  
his hisN: histidinol-phosphate phosphatase Desulfuromonas acetexigens DSM 1397 BQ4888_RS07550 BQ4888_RS03340  
his hisN: histidinol-phosphate phosphatase Desulfuromusa kysingii DSM 7343 BLU87_RS04775  
his hisN: histidinol-phosphate phosphatase Ferroglobus placidus DSM 10642 FERP_RS05525  
his hisN: histidinol-phosphate phosphatase Geobacter metallireducens GS-15 GMET_RS01925 GMET_RS03500  
his hisN: histidinol-phosphate phosphatase Geotalea uraniireducens Rf4 GURA_RS20630 GURA_RS17085  
his hisN: histidinol-phosphate phosphatase Heliomicrobium modesticaldum Ice1 Ice1; ATCC 51547 HM1_RS09170 HM1_RS04270  
his hisN: histidinol-phosphate phosphatase Hippea alviniae EP5-r G415_RS0107230  
his hisN: histidinol-phosphate phosphatase Kyrpidia tusciae DSM 2912 BTUS_RS10925 BTUS_RS05715  
his hisN: histidinol-phosphate phosphatase Leptospirillum ferrooxidans C2-3 LFE_RS10415 LFE_RS12205  
his hisN: histidinol-phosphate phosphatase Malonomonas rubra DSM 5091 BUB13_RS06010 BUB13_RS11515  
his hisN: histidinol-phosphate phosphatase Maridesulfovibrio bastinii DSM 16055 G496_RS0118070 G496_RS0107385  
his hisN: histidinol-phosphate phosphatase Maridesulfovibrio zosterae DSM 11974 H589_RS0112390 H589_RS0114445  
his hisN: histidinol-phosphate phosphatase Methanobacterium lacus AL-21 METBO_RS00375  
his hisN: histidinol-phosphate phosphatase Methanococcus aeolicus Nankai-3 MAEO_RS00710  
his hisN: histidinol-phosphate phosphatase Methanococcus maripaludis C5 MMARC5_RS05350  
his hisN: histidinol-phosphate phosphatase Methanosarcina acetivorans C2A MA_RS01180  
his hisN: histidinol-phosphate phosphatase Methanosarcina mazei Go1 MM_RS07775  
his hisN: histidinol-phosphate phosphatase Methanospirillum lacunae Ki8-1 DK846_RS02880  
his hisN: histidinol-phosphate phosphatase Methanothermobacter thermautotrophicus str. Delta H MTH_RS07010  
his hisN: histidinol-phosphate phosphatase Nitratifractor salsuginis DSM 16511 NITSA_RS03500 NITSA_RS04790  
his hisN: histidinol-phosphate phosphatase Nitratiruptor tergarcus DSM 16512 B8779_RS00360 B8779_RS06750  
his hisN: histidinol-phosphate phosphatase Nostoc punctiforme PCC 73102 ATCC 29133; PCC 73102 NPUN_RS22840 NPUN_RS27880  
his hisN: histidinol-phosphate phosphatase Paucidesulfovibrio gracilis DSM 16080 B5D49_RS00050 B5D49_RS06110  
his hisN: histidinol-phosphate phosphatase Pelobacter propionicus DSM 2379 PPRO_RS15085 PPRO_RS00085  
his hisN: histidinol-phosphate phosphatase Persephonella marina EX-H1 PERMA_RS02725 PERMA_RS01120  
his hisN: histidinol-phosphate phosphatase Pyrolobus fumarii 1A PYRFU_RS08460  
his hisN: histidinol-phosphate phosphatase Roseburia faecis M72 M72_RS13655 M72_RS08065  
his hisN: histidinol-phosphate phosphatase Sulfuricurvum kujiense DSM 16994 SULKU_RS11025 SULKU_RS07205  
his hisN: histidinol-phosphate phosphatase Sulfurihydrogenibium azorense Az-Fu1 SULAZ_RS04700 SULAZ_RS02345  
his hisN: histidinol-phosphate phosphatase Sulfurihydrogenibium subterraneum DSM 15120 Q385_RS0107105 Q385_RS0102695  
his hisN: histidinol-phosphate phosphatase Sulfurimonas denitrificans DSM 1251 SUDEN_RS09690 SUDEN_RS05675  
his hisN: histidinol-phosphate phosphatase Synechococcus elongatus PCC 7942 Synpcc7942_1763 Synpcc7942_0125  
his hisN: histidinol-phosphate phosphatase Thermoanaerobacter kivui LKT-1 TKV_RS11355 TKV_RS08960  
his hisN: histidinol-phosphate phosphatase Thermocrinis albus DSM 14484 THAL_RS01500 THAL_RS05410 spurious
his hisN: histidinol-phosphate phosphatase Thermodesulforhabdus norvegica DSM 9990 BM091_RS12655 BM091_RS00250  
his hisN: histidinol-phosphate phosphatase Thermovibrio ammonificans HB-1 THEAM_RS08080 THEAM_RS03365  
his hisN: histidinol-phosphate phosphatase Trichlorobacter lovleyi SZ GLOV_RS04040 GLOV_RS01995  
his hisN: histidinol-phosphate phosphatase Trichodesmium erythraeum IMS101 Annotated Metagenome-Assembled Genome Ga0074568_11872 Ga0074568_112237  
his hisN: histidinol-phosphate phosphatase Trichormus variabilis ATCC 29413 AVA_RS16635 AVA_RS16870  
his prs: ribose-phosphate diphosphokinase Nocardiopsis lucentensis DSM 44048 D471_RS33230  
his prs: ribose-phosphate diphosphokinase Pseudomonas fluorescens FW300-N1B4 spurious
ile cimA: (R)-citramalate synthase Stenotrophomonas chelatiphaga DSM 21508 ABB28_RS14490  
ile ilvC: 2-hydroxy-3-ketol-acid reductoisomerase Herbaspirillum autotrophicum IAM 14942 AKL27_RS26800 AKL27_RS09680  
ile ilvC: 2-hydroxy-3-ketol-acid reductoisomerase Methylobacterium nodulans ORS 2060 spurious
ile ilvD: dihydroxy-acid dehydratase Desulfotalea psychrophila LSv54 spurious
ile ilvD: dihydroxy-acid dehydratase Desulfovibrio oxyclinae DSM 11498  
ile ilvE: isoleucine transaminase Nostoc punctiforme PCC 73102 ATCC 29133; PCC 73102 NPUN_RS03530 NPUN_RS33160  
ile ilvE: isoleucine transaminase Pyrolobus fumarii 1A PYRFU_RS08035  
ile ilvE: isoleucine transaminase Trichormus variabilis ATCC 29413 AVA_RS09755  
ile ilvH: acetolactate/acetohydroxybutanoate synthase regulatory subunit Brevundimonas sp. GW460-12-10-14-LB2 A4249_RS10015  
ile ilvH: acetolactate/acetohydroxybutanoate synthase regulatory subunit Pyrolobus fumarii 1A PYRFU_RS08325  
ile ilvI: acetolactate/acetohydroxybutanoate synthase catalytic subunit Nocardiopsis lucentensis DSM 44048 D471_RS0116105 spurious
ile leuB: 3-methylmalate dehydrogenase / 3-isopropylmalate dehydrogenase Methanosarcina acetivorans C2A MA_RS19530 MA_RS01080  
ile leuB: 3-methylmalate dehydrogenase / 3-isopropylmalate dehydrogenase Methanosarcina mazei Go1 MM_RS03355 MM_RS07685  
ile leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Acidimicrobium ferrooxidans DSM 10331 AFER_RS07935 AFER_RS07275  
ile leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Leptospirillum ferrooxidans C2-3 LFE_RS04105 LFE_RS09315  
ile leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Methylohalobius crimeensis 10Ki H035_RS0104800 H035_RS0101725  
leu ilvC: 2-hydroxy-3-ketol-acid reductoisomerase Herbaspirillum autotrophicum IAM 14942 AKL27_RS26800 AKL27_RS09680  
leu ilvC: 2-hydroxy-3-ketol-acid reductoisomerase Methylobacterium nodulans ORS 2060 spurious
leu ilvD: dihydroxy-acid dehydratase Desulfotalea psychrophila LSv54 spurious
leu ilvD: dihydroxy-acid dehydratase Desulfovibrio oxyclinae DSM 11498  
leu ilvE: leucine transaminase Nostoc punctiforme PCC 73102 ATCC 29133; PCC 73102 NPUN_RS03530 NPUN_RS33160  
leu ilvE: leucine transaminase Pyrolobus fumarii 1A PYRFU_RS08035  
leu ilvE: leucine transaminase Trichormus variabilis ATCC 29413 AVA_RS09755  
leu ilvH: acetolactate/acetohydroxybutanoate synthase regulatory subunit Brevundimonas sp. GW460-12-10-14-LB2 A4249_RS10015  
leu ilvH: acetolactate/acetohydroxybutanoate synthase regulatory subunit Pyrolobus fumarii 1A PYRFU_RS08325  
leu ilvI: acetolactate/acetohydroxybutanoate synthase catalytic subunit Nocardiopsis lucentensis DSM 44048 D471_RS0116105 spurious
leu leuA: 2-isopropylmalate synthase Desulfobacter vibrioformis DSM 8776 Q366_RS07565 Q366_RS14820  
leu leuA: 2-isopropylmalate synthase Halomonas desiderata SP1  
leu leuB: 3-methylmalate dehydrogenase / 3-isopropylmalate dehydrogenase Methanosarcina acetivorans C2A MA_RS19530 MA_RS01080  
leu leuB: 3-methylmalate dehydrogenase / 3-isopropylmalate dehydrogenase Methanosarcina mazei Go1 MM_RS03355 MM_RS07685  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Acidimicrobium ferrooxidans DSM 10331 AFER_RS07935 AFER_RS07275  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Acidithiobacillus ferrooxidans ATCC 23270 AFE_RS02940 AFE_RS01995  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Allochromatium vinosum DSM 180 ALVIN_RS07965 ALVIN_RS00390  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Desulfogranum mediterraneum DSM 13871 G494_RS0100220 G494_RS0118470  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Desulfotalea psychrophila LSv54 DP_RS10020 DP_RS00645  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Desulfuromonas acetexigens DSM 1397 BQ4888_RS00460 BQ4888_RS06920  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Desulfuromusa kysingii DSM 7343 BLU87_RS11905 BLU87_RS05675  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Geobacter metallireducens GS-15 GMET_RS06390 GMET_RS13850  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Geotalea uraniireducens Rf4 GURA_RS18885 GURA_RS06455  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Halorhodospira halophila SL1 HHAL_RS09135 HHAL_RS07115  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Leptospirillum ferrooxidans C2-3 LFE_RS04105 LFE_RS09315  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Methylohalobius crimeensis 10Ki H035_RS0104800 H035_RS0101725  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Nitrosopumilus maritimus SCM1 NMAR_RS02265 NMAR_RS02255  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Thermithiobacillus tepidarius DSM 3134 G579_RS0103425 G579_RS0113635  
leu leuD: 3-isopropylmalate dehydaratase / citramalate isomerase, small subunit Trichlorobacter lovleyi SZ GLOV_RS15655 GLOV_RS07970  
lys asp-kinase: aspartate kinase Halococcus hamelinensis 100A6 C447_RS02970  
lys asp-kinase: aspartate kinase Haloferax volcanii DS2 C498_RS17705  
lys dapA: 4-hydroxy-tetrahydrodipicolinate synthase Methanothermobacter thermautotrophicus str. Delta H spurious
lys dapB: 4-hydroxy-tetrahydrodipicolinate reductase Chlorobium phaeobacteroides BS1 Cphamn1_2084  
lys dapB: 4-hydroxy-tetrahydrodipicolinate reductase Lysobacter soli OAE881 GGC55_RS05770  
lys dapB: 4-hydroxy-tetrahydrodipicolinate reductase Prosthecochloris aestuarii DSM 271 PAES_RS09415  
lys dapB: 4-hydroxy-tetrahydrodipicolinate reductase Stenotrophomonas chelatiphaga DSM 21508 ABB28_RS13580  
lys dapB: 4-hydroxy-tetrahydrodipicolinate reductase Xanthomonas campestris pv. campestris strain 8004 Xcc-8004.2915.1  
lys dapC: N-succinyldiaminopimelate aminotransferase Arcobacter nitrofigilis DSM 7299 ARNIT_RS14300 ARNIT_RS01155  
lys dapC: N-succinyldiaminopimelate aminotransferase Caminibacter mediatlanticus TB-2 CMTB2_RS00510 CMTB2_RS01140  
lys dapC: N-succinyldiaminopimelate aminotransferase Chlorobaculum parvum NCIB 8327 CPAR_RS10040 CPAR_RS04020  
lys dapC: N-succinyldiaminopimelate aminotransferase Chlorobaculum tepidum TLS AYT24_RS00350 AYT24_RS01790  
lys dapC: N-succinyldiaminopimelate aminotransferase Chlorobium limicola DSM 245 CLIM_RS11550 CLIM_RS09840  
lys dapC: N-succinyldiaminopimelate aminotransferase Halococcus hamelinensis 100A6 C447_RS04645 C447_RS12035  
lys dapC: N-succinyldiaminopimelate aminotransferase Haloferax volcanii DS2 C498_RS08325 C498_RS17875  
lys dapC: N-succinyldiaminopimelate aminotransferase Nitratifractor salsuginis DSM 16511 NITSA_RS10120 NITSA_RS09790  
lys dapC: N-succinyldiaminopimelate aminotransferase Nitratiruptor tergarcus DSM 16512 B8779_RS08925 B8779_RS08250  
lys dapC: N-succinyldiaminopimelate aminotransferase Sulfuricurvum kujiense DSM 16994 SULKU_RS04095 SULKU_RS11860  
lys dapC: N-succinyldiaminopimelate aminotransferase Sulfurimonas denitrificans DSM 1251 SUDEN_RS03970 SUDEN_RS06570  
lys dapD: tetrahydrodipicolinate succinylase Caminibacter mediatlanticus TB-2 CMTB2_RS05565  
lys dapD: tetrahydrodipicolinate succinylase Halococcus hamelinensis 100A6 C447_RS16725  
lys dapD: tetrahydrodipicolinate succinylase Haloferax volcanii DS2 C498_RS12820  
lys dapE: succinyl-diaminopimelate desuccinylase Chlorobaculum parvum NCIB 8327 CPAR_RS05010  
lys dapE: succinyl-diaminopimelate desuccinylase Chlorobaculum tepidum TLS AYT24_RS04830  
lys dapE: succinyl-diaminopimelate desuccinylase Chlorobium limicola DSM 245 CLIM_RS06275  
lys dapE: succinyl-diaminopimelate desuccinylase Chlorobium phaeobacteroides BS1 Cphamn1_1324  
lys dapE: succinyl-diaminopimelate desuccinylase Halococcus hamelinensis 100A6 C447_RS15935 C447_RS15005  
lys dapE: succinyl-diaminopimelate desuccinylase Haloferax volcanii DS2 C498_RS00930 C498_RS01700  
lys dapE: succinyl-diaminopimelate desuccinylase Mucilaginibacter yixingensis DSM 26809 C8P68_RS00720  
lys dapE: succinyl-diaminopimelate desuccinylase Pedobacter sp. GW460-11-11-14-LB5 CA265_RS23900 CA265_RS17965  
lys dapF: diaminopimelate epimerase Cereibacter sphaeroides ATCC 17029 RSPH17029_RS13090  
lys dapF: diaminopimelate epimerase Lysobacter soli OAE881 GGC55_RS14475  
lys dapF: diaminopimelate epimerase Methanosarcina acetivorans C2A  
lys dapF: diaminopimelate epimerase Methanosarcina mazei Go1  
lys dapF: diaminopimelate epimerase Methylocystis bryophila S285 B1812_RS00195  
lys dapF: diaminopimelate epimerase Methylovulum miyakonense HT12 spurious
lys dapF: diaminopimelate epimerase Rhodospirillum rubrum ATCC 11170 RRU_RS06195  
lys dapF: diaminopimelate epimerase Stenotrophomonas chelatiphaga DSM 21508 ABB28_RS12205  
lys dapF: diaminopimelate epimerase Xanthomonas campestris pv. campestris strain 8004 Xcc-8004.845.1  
lys dapL: N-acetyl-diaminopimelate deacetylase Clostridium kluyveri DSM 555 CKL_RS07285 CKL_RS03195  
lys dapL: N-acetyl-diaminopimelate deacetylase Thermoanaerobacter kivui LKT-1 TKV_RS02810  
lys DAPtransferase: L,L-diaminopimelate aminotransferase Aquimarina longa SW024 N456_RS09260  
lys DAPtransferase: L,L-diaminopimelate aminotransferase Clostridium tyrobutyricum FAM22553 PN53_RS09355 PN53_RS11745  
lys DAPtransferase: L,L-diaminopimelate aminotransferase Desulfotalea psychrophila LSv54 DP_RS14870 spurious
lys DAPtransferase: L,L-diaminopimelate aminotransferase Echinicola vietnamensis KMM 6221, DSM 17526 Echvi_0124  
lys DAPtransferase: L,L-diaminopimelate aminotransferase Prosthecochloris aestuarii DSM 271 PAES_RS04825  
lys DAPtransferase: L,L-diaminopimelate aminotransferase Thioalkalivibrio halophilus HL17 B1A74_RS05205 B1A74_RS04935  
lys DAPtransferase: L,L-diaminopimelate aminotransferase Thioalkalivibrio paradoxus ARh 1 THITH_RS04650 THITH_RS07035  
lys DAPtransferase: L,L-diaminopimelate aminotransferase Thiomicrorhabdus arctica DSM 13458 F612_RS0102765 F612_RS0106445  
lys dapX: acetyl-diaminopimelate aminotransferase Kyrpidia tusciae DSM 2912 BTUS_RS03510 BTUS_RS16335  
lys dapX: acetyl-diaminopimelate aminotransferase Thermoanaerobacter kivui LKT-1 TKV_RS01225 TKV_RS00950  
lys hcs: homocitrate synthase Nitrosopumilus maritimus SCM1 NMAR_RS05735 NMAR_RS06925  
lys hicdh: homo-isocitrate dehydrogenase Nitrosopumilus maritimus SCM1 NMAR_RS05730 NMAR_RS07395  
lys hicdh: homo-isocitrate dehydrogenase Pyrolobus fumarii 1A PYRFU_RS09335 PYRFU_RS05270  
lys lysA: diaminopimelate decarboxylase Anaerobutyricum hallii DSM 3353 EUBHAL_RS03150  
lys lysA: diaminopimelate decarboxylase Desulfobacter vibrioformis DSM 8776 Q366_RS09195 Q366_RS06995  
lys lysA: diaminopimelate decarboxylase Desulfogranum mediterraneum DSM 13871 G494_RS0107965 G494_RS22485  
lys lysA: diaminopimelate decarboxylase Desulfoscipio geothermicus DSM 3669 BM299_RS12230  
lys lysA: diaminopimelate decarboxylase Desulfuromonas acetexigens DSM 1397 BQ4888_RS11435  
lys lysA: diaminopimelate decarboxylase Desulfuromusa kysingii DSM 7343 BLU87_RS10740  
lys lysA: diaminopimelate decarboxylase Geobacter metallireducens GS-15 GMET_RS01100 GMET_RS10195  
lys lysA: diaminopimelate decarboxylase Malonomonas rubra DSM 5091 BUB13_RS00270  
lys lysA: diaminopimelate decarboxylase Pelobacter propionicus DSM 2379 PPRO_RS09900  
lys lysA: diaminopimelate decarboxylase Roseburia faecis M72 M72_RS01060  
lys lysA: diaminopimelate decarboxylase Trichlorobacter lovleyi SZ GLOV_RS14990  
lys lysK: [LysW]-lysine hydrolase Nitrosopumilus maritimus SCM1 NMAR_RS06940  
lys lysK: [LysW]-lysine hydrolase Pyrolobus fumarii 1A PYRFU_RS08530  
lys lysN: 2-aminoadipate:2-oxoglutarate aminotransferase Nitrosopumilus maritimus SCM1 NMAR_RS06915 NMAR_RS00915  
lys lysN: 2-aminoadipate:2-oxoglutarate aminotransferase Pyrolobus fumarii 1A PYRFU_RS08035 PYRFU_RS08855  
lys lysT: homoaconitase large subunit Nitrosopumilus maritimus SCM1 NMAR_RS02250 NMAR_RS02260  
lys lysU: homoaconitase small subunit Nitrosopumilus maritimus SCM1 NMAR_RS02255 NMAR_RS02265  
lys lysU: homoaconitase small subunit Pyrolobus fumarii 1A PYRFU_RS07965 PYRFU_RS03665  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Archaeoglobus veneficus SNP6 ARCVE_RS05390  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Crocosphaera subtropica ATCC 51142 CCE_RS04625  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Desulfarculus baarsii DSM 2075 DEBA_RS15765  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Ferroglobus placidus DSM 10642 FERP_RS09805 FERP_RS04470  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Methanococcus aeolicus Nankai-3 MAEO_RS03975 MAEO_RS01850  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Methanococcus maripaludis C5 MMARC5_RS01115 MMARC5_RS00585  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Methanothermobacter thermautotrophicus str. Delta H MTH_RS04025 MTH_RS07435  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Thermodesulforhabdus norvegica DSM 9990 BM091_RS07495  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Thermovibrio ammonificans HB-1 THEAM_RS00955  
met asd-S-ferredoxin: L-aspartate semialdehyde sulfurtransferase, NIL/ferredoxin component Trichodesmium erythraeum IMS101 Annotated Metagenome-Assembled Genome Ga0074568_111455  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Crocosphaera subtropica ATCC 51142  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Dehalococcoides mccartyi 195 DET_RS04785  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Desulfatibacillum aliphaticivorans DSM 15576 G491_RS0114640  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Desulfatiglans anilini DSM 4660 H567_RS0107765  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Desulfobacca acetoxidans DSM 11109 DESAC_RS10290  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Desulfobacter vibrioformis DSM 8776 Q366_RS07305  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Desulfurobacterium atlanticum DSM 15668 CHB58_RS01920  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Hippea alviniae EP5-r G415_RS0107280  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Methanothermobacter thermautotrophicus str. Delta H MTH_RS03410  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Thermodesulforhabdus norvegica DSM 9990 BM091_RS02260  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Thermovibrio ammonificans HB-1 THEAM_RS06115  
met asd-S-perS: L-aspartate semialdehyde sulfurtransferase, persulfide-forming component Trichodesmium erythraeum IMS101 Annotated Metagenome-Assembled Genome  
met asp-kinase: aspartate kinase Halococcus hamelinensis 100A6 C447_RS02970  
met asp-kinase: aspartate kinase Haloferax volcanii DS2 C498_RS17705  
met B12-reactivation-domain: MetH reactivation domain Desulfogranum mediterraneum DSM 13871 G494_RS0103145  
met B12-reactivation-domain: MetH reactivation domain Desulfuromusa kysingii DSM 7343 BLU87_RS06905  
met B12-reactivation-domain: MetH reactivation domain Haloglycomyces albus DSM 45210 HALAL_RS0113755  
met B12-reactivation-domain: MetH reactivation domain Heliomicrobium modesticaldum Ice1 Ice1; ATCC 51547 HM1_RS11405  
met B12-reactivation-domain: MetH reactivation domain Leptospirillum ferrooxidans C2-3 LFE_RS08450  
met B12-reactivation-domain: MetH reactivation domain Phaeacidiphilus oryzae TH49 BS73_RS09345  
met B12-reactivation-domain: MetH reactivation domain Thermomonospora curvata DSM 43183 TCUR_RS11345  
met B12-reactivation-domain: MetH reactivation domain Thermus aquaticus YT-1 BVI061214_RS08750  
met hom: homoserine dehydrogenase Halococcus hamelinensis 100A6 C447_RS05685  
met hom: homoserine dehydrogenase Haloferax volcanii DS2 C498_RS16345 C498_RS15195  
met hom: homoserine dehydrogenase Nitrosopumilus maritimus SCM1 NMAR_RS03730 NMAR_RS09380  
met hom: homoserine dehydrogenase Pyrolobus fumarii 1A PYRFU_RS06440  
met hom: homoserine dehydrogenase Roseburia faecis M72 M72_RS01920 M72_RS09220  
met hom_kinase: homoserine kinase Acidimicrobium ferrooxidans DSM 10331 AFER_RS03340 AFER_RS01155  
met mesB: Methylcobalamin:homocysteine methyltransferase MesB Carboxydothermus pertinax Ug1 cpu_RS01415  
met mesB: Methylcobalamin:homocysteine methyltransferase MesB Desulfacinum hydrothermale DSM 13146 B9A12_RS10415  
met mesB: Methylcobalamin:homocysteine methyltransferase MesB Desulfacinum infernum DSM 9756 BUB04_RS04080  
met mesB: Methylcobalamin:homocysteine methyltransferase MesB Desulfarculus baarsii DSM 2075 DEBA_RS11000  
met mesB: Methylcobalamin:homocysteine methyltransferase MesB Desulfatibacillum aliphaticivorans DSM 15576 G491_RS0128095  
met mesB: Methylcobalamin:homocysteine methyltransferase MesB Desulfatiglans anilini DSM 4660 H567_RS0109315  
met mesB: Methylcobalamin:homocysteine methyltransferase MesB Desulfitobacterium hafniense DCB-2 DHAF_RS11500  
met mesB: Methylcobalamin:homocysteine methyltransferase MesB Thermodesulforhabdus norvegica DSM 9990 BM091_RS04305  
met mesC: Methylcobalamin:homocysteine methyltransferase MesC Archaeoglobus veneficus SNP6 ARCVE_RS08725  
met mesC: Methylcobalamin:homocysteine methyltransferase MesC Ferroglobus placidus DSM 10642 FERP_RS08670  
met mesC: Methylcobalamin:homocysteine methyltransferase MesC Methanosarcina acetivorans C2A MA_RS00270 MA_RS18535  
met mesC: Methylcobalamin:homocysteine methyltransferase MesC Methanosarcina mazei Go1 MM_RS07010 MM_RS02470  
met metB: cystathionine gamma-synthase Acidimicrobium ferrooxidans DSM 10331 AFER_RS07735  
met metB: cystathionine gamma-synthase Aquimarina longa SW024 N456_RS09485 N456_RS11780  
met metB: cystathionine gamma-synthase Leptospirillum ferrooxidans C2-3 LFE_RS02030  
met metB: cystathionine gamma-synthase Nitrosopumilus maritimus SCM1  
met metB: cystathionine gamma-synthase Persephonella marina EX-H1  
met metB: cystathionine gamma-synthase Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_4890 Pf1N1B4_4430  
met metB: cystathionine gamma-synthase Pyrolobus fumarii 1A PYRFU_RS03465  
met metB: cystathionine gamma-synthase Sulfurihydrogenibium azorense Az-Fu1  
met metB: cystathionine gamma-synthase Sulfurihydrogenibium subterraneum DSM 15120  
met metB: cystathionine gamma-synthase Thermocrinis albus DSM 14484  
met metC: cystathionine beta-lyase Acidimicrobium ferrooxidans DSM 10331 AFER_RS07735 AFER_RS10005  
met metC: cystathionine beta-lyase Haloechinothrix alba DSM 45207 CHB84_RS02120 CHB84_RS07990  
met metC: cystathionine beta-lyase Haloglycomyces albus DSM 45210 HALAL_RS0104995 HALAL_RS0101720  
met metC: cystathionine beta-lyase Leptospirillum ferrooxidans C2-3 LFE_RS02030 LFE_RS07250  
met metC: cystathionine beta-lyase Nitrosopumilus maritimus SCM1  
met metC: cystathionine beta-lyase Nocardioides dokdonensis FR1436 I601_RS09970 I601_RS12345  
met metC: cystathionine beta-lyase Nocardiopsis lucentensis DSM 44048 D471_RS0107605 D471_RS0102240  
met metC: cystathionine beta-lyase Persephonella marina EX-H1  
met metC: cystathionine beta-lyase Pyrolobus fumarii 1A PYRFU_RS03465  
met metC: cystathionine beta-lyase Sulfurihydrogenibium azorense Az-Fu1 SULAZ_RS01475  
met metC: cystathionine beta-lyase Sulfurihydrogenibium subterraneum DSM 15120 Q385_RS0103460  
met metC: cystathionine beta-lyase Thermocrinis albus DSM 14484  
met metE: vitamin B12-independent methionine synthase Acidithiobacillus ferrooxidans ATCC 23270 AFE_RS01365  
met metH: vitamin B12-dependent methionine synthase Desulfotalea psychrophila LSv54 DP_RS11245 with DP_RS11240  
met metH: vitamin B12-dependent methionine synthase Desulfuromusa kysingii DSM 7343 BLU87_RS06905 with BLU87_RS06900  
met metH: vitamin B12-dependent methionine synthase Hippea alviniae EP5-r G415_RS0102895  
met metH: vitamin B12-dependent methionine synthase Nitriliruptor alkaliphilus DSM 45188 NITAL_RS03045  
met metH: vitamin B12-dependent methionine synthase Nitrosopumilus maritimus SCM1 NMAR_RS06795 with NMAR_RS06800  
met split_metE_1: vitamin B12-independent methionine synthase, folate-binding component Halococcus hamelinensis 100A6 C447_RS08500  
met split_metE_1: vitamin B12-independent methionine synthase, folate-binding component Haloferax volcanii DS2 C498_RS08730  
met split_metE_1: vitamin B12-independent methionine synthase, folate-binding component Pyrolobus fumarii 1A PYRFU_RS09465  
met split_metE_2: vitamin B12-independent methionine synthase, catalytic component Halococcus hamelinensis 100A6 C447_RS08505  
met split_metE_2: vitamin B12-independent methionine synthase, catalytic component Haloferax volcanii DS2 C498_RS08725  
met split_metE_2: vitamin B12-independent methionine synthase, catalytic component Pyrolobus fumarii 1A PYRFU_RS01495  
phe aro-dehydratase: arogenate dehydratase Chlorobaculum parvum NCIB 8327 CPAR_RS02680  
phe aro-dehydratase: arogenate dehydratase Chlorobaculum tepidum TLS AYT24_RS07510  
phe aro-dehydratase: arogenate dehydratase Chlorobium limicola DSM 245 CLIM_RS02420  
phe aro-dehydratase: arogenate dehydratase Chlorobium phaeobacteroides BS1 Cphamn1_0541  
phe aro-dehydratase: arogenate dehydratase Desulfacinum hydrothermale DSM 13146 B9A12_RS07670  
phe aro-dehydratase: arogenate dehydratase Desulfogranum mediterraneum DSM 13871 G494_RS0101895  
phe aro-dehydratase: arogenate dehydratase Desulfovibrio oxyclinae DSM 11498 B149_RS16240 B149_RS0112780  
phe aro-dehydratase: arogenate dehydratase Prosthecochloris aestuarii DSM 271 PAES_RS02470  
phe aro-dehydratase: arogenate dehydratase Thermodesulforhabdus norvegica DSM 9990 BM091_RS03430 BM091_RS06270  
phe aro-dehydratase: arogenate dehydratase Thermus aquaticus YT-1 BVI061214_RS11665  
phe cmutase: chorismate mutase Clostridium acetobutylicum ATCC 824 CA_RS04760 CA_RS16245  
phe PPYAT: phenylpyruvate aminotransferase Haloglycomyces albus DSM 45210 HALAL_RS0106545 HALAL_RS0107745  
phe PPYAT: phenylpyruvate aminotransferase Pyrolobus fumarii 1A PYRFU_RS08035 PYRFU_RS03405  
phe preph-dehydratase: prephenate dehydratase Acidimicrobium ferrooxidans DSM 10331 AFER_RS00495  
phe preph-dehydratase: prephenate dehydratase Alkalihalobacterium alkalinitrilicum DSM 22532 BK574_RS13700  
phe preph-dehydratase: prephenate dehydratase Anaerobutyricum hallii DSM 3353 EUBHAL_RS06695  
phe preph-dehydratase: prephenate dehydratase Arcobacter nitrofigilis DSM 7299 ARNIT_RS02150  
phe preph-dehydratase: prephenate dehydratase Caminibacter mediatlanticus TB-2 CMTB2_RS03830  
phe preph-dehydratase: prephenate dehydratase Carboxydothermus pertinax Ug1 cpu_RS05670  
phe preph-dehydratase: prephenate dehydratase Clostridium acetobutylicum ATCC 824 CA_RS01215 CA_RS18625  
phe preph-dehydratase: prephenate dehydratase Clostridium kluyveri DSM 555 CKL_RS03870  
phe preph-dehydratase: prephenate dehydratase Clostridium tyrobutyricum FAM22553 PN53_RS02450  
phe preph-dehydratase: prephenate dehydratase Crocosphaera subtropica ATCC 51142 CCE_RS21960  
phe preph-dehydratase: prephenate dehydratase Dehalococcoides mccartyi 195 DET_RS02500 DET_RS07920  
phe preph-dehydratase: prephenate dehydratase Desulfitobacterium hafniense DCB-2 DHAF_RS15220  
phe preph-dehydratase: prephenate dehydratase Desulfobacter vibrioformis DSM 8776 Q366_RS16530  
phe preph-dehydratase: prephenate dehydratase Desulforamulus ruminis DSM 2154 DESRU_RS13125  
phe preph-dehydratase: prephenate dehydratase Kyrpidia tusciae DSM 2912 BTUS_RS04750  
phe preph-dehydratase: prephenate dehydratase Maridesulfovibrio bastinii DSM 16055 G496_RS0100775  
phe preph-dehydratase: prephenate dehydratase Methanosarcina acetivorans C2A MA_RS16475  
phe preph-dehydratase: prephenate dehydratase Methanosarcina mazei Go1 MM_RS02000  
phe preph-dehydratase: prephenate dehydratase Methanospirillum lacunae Ki8-1 DK846_RS01965  
phe preph-dehydratase: prephenate dehydratase Nitratifractor salsuginis DSM 16511 NITSA_RS01510  
phe preph-dehydratase: prephenate dehydratase Nitratiruptor tergarcus DSM 16512 B8779_RS04265  
phe preph-dehydratase: prephenate dehydratase Nitrosopumilus maritimus SCM1 NMAR_RS08395  
phe preph-dehydratase: prephenate dehydratase Nostoc punctiforme PCC 73102 ATCC 29133; PCC 73102 NPUN_RS19645  
phe preph-dehydratase: prephenate dehydratase Roseburia faecis M72 M72_RS08525  
phe preph-dehydratase: prephenate dehydratase Sulfuricurvum kujiense DSM 16994 SULKU_RS09630  
phe preph-dehydratase: prephenate dehydratase Sulfurimonas denitrificans DSM 1251 SUDEN_RS02465  
phe preph-dehydratase: prephenate dehydratase Synechococcus elongatus PCC 7942 Synpcc7942_0881  
phe preph-dehydratase: prephenate dehydratase Trichodesmium erythraeum IMS101 Annotated Metagenome-Assembled Genome Ga0074568_112528  
phe preph-dehydratase: prephenate dehydratase Trichormus variabilis ATCC 29413 AVA_RS06500  
pro argC: N-acylglutamylphosphate reductase Ferroglobus placidus DSM 10642 FERP_RS04630  
pro argC: N-acylglutamylphosphate reductase Methanococcus aeolicus Nankai-3 MAEO_RS06695  
pro argC: N-acylglutamylphosphate reductase Methanococcus maripaludis C5 MMARC5_RS07930 MMARC5_RS00960  
pro argC: N-acylglutamylphosphate reductase Methanothermobacter thermautotrophicus str. Delta H MTH_RS03985  
pro argD: N-acetylornithine aminotransferase Aquimarina longa SW024 N456_RS18100 N456_RS16190  
pro argE: N-acetylornithine deacetylase Aquimarina longa SW024 N456_RS06765  
pro argX: glutamate--LysW ligase Halococcus hamelinensis 100A6 C447_RS04730  
pro argX: glutamate--LysW ligase Haloferax volcanii DS2 C498_RS17890  
pro cyclodeaminase: ornithine cyclodeaminase Pyrolobus fumarii 1A PYRFU_RS04150  
pro lysJ: [LysW]-glutamate-semialdehyde aminotransferase Haloferax volcanii DS2 C498_RS17875 C498_RS02300  
pro lysK: [LysW]-ornithine hydrolase Halococcus hamelinensis 100A6 C447_RS16710 C447_RS04710  
pro lysK: [LysW]-ornithine hydrolase Haloferax volcanii DS2 C498_RS12835 C498_RS17870  
pro lysK: [LysW]-ornithine hydrolase Nitrosopumilus maritimus SCM1 NMAR_RS06940  
pro lysK: [LysW]-ornithine hydrolase Pyrolobus fumarii 1A PYRFU_RS08530  
pro lysZ: [LysW]-glutamate kinase Halococcus hamelinensis 100A6 C447_RS04720  
pro lysZ: [LysW]-glutamate kinase Haloferax volcanii DS2 C498_RS17880  
pro OAT: L-ornithine 5-aminotransferase Clostridium tyrobutyricum FAM22553 PN53_RS11750 PN53_RS10390  
pro proB: glutamate 5-kinase Anaerobutyricum hallii DSM 3353 EUBHAL_RS06035 EUBHAL_RS06040  
pro proB: glutamate 5-kinase Clostridium kluyveri DSM 555 CKL_RS13390 CKL_RS04535  
pro proB: glutamate 5-kinase Roseburia faecis M72 M72_RS08265 M72_RS08250  
ser serA: 3-phosphoglycerate dehydrogenase Algiphilus aromaticivorans DG1253 U743_RS06090  
ser serA: 3-phosphoglycerate dehydrogenase Anaerobutyricum hallii DSM 3353 EUBHAL_RS13315  
ser serA: 3-phosphoglycerate dehydrogenase Chlorobaculum parvum NCIB 8327 spurious
ser serA: 3-phosphoglycerate dehydrogenase Chlorobaculum tepidum TLS spurious
ser serA: 3-phosphoglycerate dehydrogenase Chlorobium phaeobacteroides BS1 Cphamn1_1569 Cphamn1_1263  
ser serA: 3-phosphoglycerate dehydrogenase Clostridium acetobutylicum ATCC 824 CA_RS00100 CA_RS00495  
ser serA: 3-phosphoglycerate dehydrogenase Clostridium tyrobutyricum FAM22553 PN53_RS14390 PN53_RS11735  
ser serA: 3-phosphoglycerate dehydrogenase Desulfitobacterium hafniense DCB-2 DHAF_RS10215 DHAF_RS22855  
ser serA: 3-phosphoglycerate dehydrogenase Desulfogranum mediterraneum DSM 13871 G494_RS0111735 G494_RS0111035  
ser serA: 3-phosphoglycerate dehydrogenase Desulfotalea psychrophila LSv54 DP_RS08685  
ser serA: 3-phosphoglycerate dehydrogenase Desulfovibrio oxyclinae DSM 11498 B149_RS0109925 spurious
ser serA: 3-phosphoglycerate dehydrogenase Desulfovibrio vulgaris Hildenborough JW710 DVU0339 DVU1412  
ser serA: 3-phosphoglycerate dehydrogenase Desulfovibrio vulgaris Miyazaki F DvMF_1902 DvMF_0209  
ser serA: 3-phosphoglycerate dehydrogenase Hyphomicrobium sulfonivorans WDL6 APY04_RS11295 APY04_RS09155  
ser serA: 3-phosphoglycerate dehydrogenase Maridesulfovibrio bastinii DSM 16055 G496_RS0117515 G496_RS19260  
ser serA: 3-phosphoglycerate dehydrogenase Maridesulfovibrio zosterae DSM 11974 H589_RS19615 H589_RS0111585  
ser serA: 3-phosphoglycerate dehydrogenase Methyloferula stellata AR4 AR4T A3OQ_RS0116535 A3OQ_RS0106245  
ser serA: 3-phosphoglycerate dehydrogenase Methylohalobius crimeensis 10Ki H035_RS0104745 H035_RS0101750  
ser serA: 3-phosphoglycerate dehydrogenase Paucidesulfovibrio gracilis DSM 16080 B5D49_RS12715 spurious
ser serA: 3-phosphoglycerate dehydrogenase Prosthecochloris aestuarii DSM 271 spurious
ser serA: 3-phosphoglycerate dehydrogenase Roseburia faecis M72 M72_RS11035 M72_RS11705  
ser serA: 3-phosphoglycerate dehydrogenase Sulfuritalea hydrogenivorans sk43H DSM 22779 SUTH_RS16735 SUTH_RS09885  
ser serB: phosphoserine phosphatase Acidimicrobium ferrooxidans DSM 10331 AFER_RS09950 AFER_RS10145  
ser serB: phosphoserine phosphatase Algiphilus aromaticivorans DG1253 U743_RS13380 U743_RS17935  
ser serB: phosphoserine phosphatase Ammonifex degensii KC4 ADEG_RS07390 ADEG_RS06135  
ser serB: phosphoserine phosphatase Aquimarina longa SW024 N456_RS18760  
ser serB: phosphoserine phosphatase Brevundimonas sp. GW460-12-10-14-LB2 A4249_RS03295 A4249_RS17100  
ser serB: phosphoserine phosphatase Calditerrivibrio nitroreducens DSM 19672 CALNI_RS01845  
ser serB: phosphoserine phosphatase Carboxydothermus pertinax Ug1 cpu_RS03150 cpu_RS03145  
ser serB: phosphoserine phosphatase Clostridium kluyveri DSM 555 CKL_RS00935 CKL_RS02155  
ser serB: phosphoserine phosphatase Dehalococcoides mccartyi 195 DET_RS03630 DET_RS03175  
ser serB: phosphoserine phosphatase Denitrovibrio acetiphilus DSM 12809  
ser serB: phosphoserine phosphatase Desulfacinum hydrothermale DSM 13146 B9A12_RS06340 B9A12_RS05120  
ser serB: phosphoserine phosphatase Desulfacinum infernum DSM 9756 BUB04_RS14555 BUB04_RS06135  
ser serB: phosphoserine phosphatase Desulfarculus baarsii DSM 2075 DEBA_RS01805 DEBA_RS03615  
ser serB: phosphoserine phosphatase Desulfatiglans anilini DSM 4660 H567_RS0101025 H567_RS0117800  
ser serB: phosphoserine phosphatase Desulfitobacterium hafniense DCB-2 DHAF_RS14915 DHAF_RS15640  
ser serB: phosphoserine phosphatase Desulfobacca acetoxidans DSM 11109 DESAC_RS13730 DESAC_RS07905  
ser serB: phosphoserine phosphatase Desulfogranum mediterraneum DSM 13871 G494_RS0112245 G494_RS0116475  
ser serB: phosphoserine phosphatase Desulforamulus ruminis DSM 2154 DESRU_RS00110 DESRU_RS00105  
ser serB: phosphoserine phosphatase Desulfoscipio geothermicus DSM 3669 BM299_RS04405 BM299_RS17355  
ser serB: phosphoserine phosphatase Desulfotalea psychrophila LSv54 DP_RS08685 DP_RS08915  
ser serB: phosphoserine phosphatase Desulfovibrio vulgaris Hildenborough JW710 DVU3147 DVU2935  
ser serB: phosphoserine phosphatase Desulfovibrio vulgaris Miyazaki F DvMF_1696 DvMF_1462  
ser serB: phosphoserine phosphatase Desulfuromusa kysingii DSM 7343 BLU87_RS16615 BLU87_RS12805  
ser serB: phosphoserine phosphatase Dyella japonica UNC79MFTsu3.2 N515DRAFT_3581 N515DRAFT_0640  
ser serB: phosphoserine phosphatase Geobacter metallireducens GS-15 GMET_RS02345 GMET_RS08315 spurious
ser serB: phosphoserine phosphatase Geotalea uraniireducens Rf4 GURA_RS21280 GURA_RS05100 spurious
ser serB: phosphoserine phosphatase Haloglycomyces albus DSM 45210 HALAL_RS0103885 HALAL_RS0105715  
ser serB: phosphoserine phosphatase Heliomicrobium modesticaldum Ice1 Ice1; ATCC 51547 HM1_RS11600 HM1_RS05105  
ser serB: phosphoserine phosphatase Hippea alviniae EP5-r G415_RS09260 G415_RS0101445  
ser serB: phosphoserine phosphatase Hyphomicrobium sulfonivorans WDL6 APY04_RS14490 APY04_RS12045  
ser serB: phosphoserine phosphatase Leptospirillum ferrooxidans C2-3 LFE_RS06195 LFE_RS10275  
ser serB: phosphoserine phosphatase Malonomonas rubra DSM 5091 BUB13_RS14350 BUB13_RS07885  
ser serB: phosphoserine phosphatase Methanospirillum lacunae Ki8-1 DK846_RS10155 DK846_RS15290  
ser serB: phosphoserine phosphatase Methylomonas methanica MC09 METME_RS07465 METME_RS07460  
ser serB: phosphoserine phosphatase Methylosarcina fibrata AML-C10 A3OW_RS0123130 A3OW_RS0104935  
ser serB: phosphoserine phosphatase Methylotuvimicrobium alcaliphilum 20Z MEALZ_RS05030 MEALZ_RS05025  
ser serB: phosphoserine phosphatase Methylovulum miyakonense HT12 METMI_RS0100115 METMI_RS0100120  
ser serB: phosphoserine phosphatase Pelobacter propionicus DSM 2379 PPRO_RS13955 PPRO_RS03595  
ser serB: phosphoserine phosphatase Rhodanobacter denitrificans FW104-10B01 LRK54_RS17655 LRK54_RS03185  
ser serB: phosphoserine phosphatase Steroidobacter denitrificans DSM 18526 ACG33_RS01535 ACG33_RS02460  
ser serB: phosphoserine phosphatase Thermoanaerobacter kivui LKT-1 TKV_RS06110 TKV_RS11735  
ser serB: phosphoserine phosphatase Thermodesulforhabdus norvegica DSM 9990 BM091_RS09805  
ser serB: phosphoserine phosphatase Thioalkalivibrio denitrificans ALJD B1C78_RS07080 B1C78_RS07145  
ser serB: phosphoserine phosphatase Thioalkalivibrio halophilus HL17 B1A74_RS01040 B1A74_RS11150  
ser serB: phosphoserine phosphatase Thioalkalivibrio paradoxus ARh 1 THITH_RS11205 THITH_RS07690  
ser serB: phosphoserine phosphatase Thioalkalivibrio thiocyanodenitrificans ARhD 1 THITHI_RS0102410 THITHI_RS0102480  
ser serB: phosphoserine phosphatase Thiothrix lacustris DSM 21227 Q394_RS0104085 Q394_RS0102655 spurious
ser serB: phosphoserine phosphatase Trichlorobacter lovleyi SZ GLOV_RS13540 GLOV_RS10410  
ser serC: 3-phosphoserine aminotransferase Ammonifex degensii KC4 ADEG_RS00045  
ser serC: 3-phosphoserine aminotransferase Arcobacter nitrofigilis DSM 7299 ARNIT_RS01155  
ser serC: 3-phosphoserine aminotransferase Azospirillum brasilense Sp245 spurious
ser serC: 3-phosphoserine aminotransferase Calditerrivibrio nitroreducens DSM 19672 CALNI_RS01845  
ser serC: 3-phosphoserine aminotransferase Caminibacter mediatlanticus TB-2 CMTB2_RS07320  
ser serC: 3-phosphoserine aminotransferase Carboxydothermus pertinax Ug1 cpu_RS03145  
ser serC: 3-phosphoserine aminotransferase Chlorobaculum parvum NCIB 8327 CPAR_RS10040  
ser serC: 3-phosphoserine aminotransferase Chlorobaculum tepidum TLS AYT24_RS00350  
ser serC: 3-phosphoserine aminotransferase Chlorobium limicola DSM 245 CLIM_RS11550  
ser serC: 3-phosphoserine aminotransferase Clostridium kluyveri DSM 555 CKL_RS18530 CKL_RS18590  
ser serC: 3-phosphoserine aminotransferase Clostridium tyrobutyricum FAM22553 PN53_RS14945 PN53_RS14385  
ser serC: 3-phosphoserine aminotransferase Dehalococcoides mccartyi 195 DET_RS03175  
ser serC: 3-phosphoserine aminotransferase Denitrovibrio acetiphilus DSM 12809 DACET_RS12185  
ser serC: 3-phosphoserine aminotransferase Desulfarculus baarsii DSM 2075 DEBA_RS03610  
ser serC: 3-phosphoserine aminotransferase Desulfobacca acetoxidans DSM 11109 DESAC_RS06350  
ser serC: 3-phosphoserine aminotransferase Desulforamulus ruminis DSM 2154 DESRU_RS00105  
ser serC: 3-phosphoserine aminotransferase Desulfoscipio geothermicus DSM 3669 BM299_RS17360  
ser serC: 3-phosphoserine aminotransferase Desulfovibrio oxyclinae DSM 11498 B149_RS0100570  
ser serC: 3-phosphoserine aminotransferase Desulfovibrio vulgaris Hildenborough JW710 DVU0494 DVU3121  
ser serC: 3-phosphoserine aminotransferase Desulfovibrio vulgaris Miyazaki F DvMF_2809 DvMF_1715  
ser serC: 3-phosphoserine aminotransferase Desulfurobacterium atlanticum DSM 15668 CHB58_RS06165  
ser serC: 3-phosphoserine aminotransferase Desulfuromonas acetexigens DSM 1397 BQ4888_RS12980  
ser serC: 3-phosphoserine aminotransferase Echinicola vietnamensis KMM 6221, DSM 17526  
ser serC: 3-phosphoserine aminotransferase Geobacter metallireducens GS-15 GMET_RS15900  
ser serC: 3-phosphoserine aminotransferase Geotalea uraniireducens Rf4 GURA_RS04390  
ser serC: 3-phosphoserine aminotransferase Halococcus hamelinensis 100A6 C447_RS04645  
ser serC: 3-phosphoserine aminotransferase Haloferax volcanii DS2 C498_RS08325 C498_RS00245  
ser serC: 3-phosphoserine aminotransferase Hippea alviniae EP5-r G415_RS0108335  
ser serC: 3-phosphoserine aminotransferase Leptospirillum ferrooxidans C2-3 LFE_RS06190  
ser serC: 3-phosphoserine aminotransferase Maridesulfovibrio bastinii DSM 16055 G496_RS0102925  
ser serC: 3-phosphoserine aminotransferase Maridesulfovibrio zosterae DSM 11974 H589_RS0107780  
ser serC: 3-phosphoserine aminotransferase Nitratifractor salsuginis DSM 16511 NITSA_RS09790  
ser serC: 3-phosphoserine aminotransferase Nitratiruptor tergarcus DSM 16512 B8779_RS01105  
ser serC: 3-phosphoserine aminotransferase Paucidesulfovibrio gracilis DSM 16080 B5D49_RS02330  
ser serC: 3-phosphoserine aminotransferase Persephonella marina EX-H1 PERMA_RS01695  
ser serC: 3-phosphoserine aminotransferase Prosthecochloris aestuarii DSM 271 spurious
ser serC: 3-phosphoserine aminotransferase Pyrolobus fumarii 1A PYRFU_RS03405  
ser serC: 3-phosphoserine aminotransferase Sulfuricurvum kujiense DSM 16994 SULKU_RS11860  
ser serC: 3-phosphoserine aminotransferase Sulfurihydrogenibium azorense Az-Fu1 SULAZ_RS02850 spurious
ser serC: 3-phosphoserine aminotransferase Sulfurihydrogenibium subterraneum DSM 15120 Q385_RS0102205  
ser serC: 3-phosphoserine aminotransferase Sulfurimonas denitrificans DSM 1251 SUDEN_RS00385  
ser serC: 3-phosphoserine aminotransferase Thermoanaerobacter kivui LKT-1 TKV_RS11400  
ser serC: 3-phosphoserine aminotransferase Thermocrinis albus DSM 14484 THAL_RS04470  
ser serC: 3-phosphoserine aminotransferase Thermovibrio ammonificans HB-1 THEAM_RS01165  
ser serC: 3-phosphoserine aminotransferase Thermus aquaticus YT-1 BVI061214_RS08670 BVI061214_RS04695  
ser serC: 3-phosphoserine aminotransferase Trichlorobacter lovleyi SZ GLOV_RS16555  
thr asp-kinase: aspartate kinase Halococcus hamelinensis 100A6 C447_RS02970  
thr asp-kinase: aspartate kinase Haloferax volcanii DS2 C498_RS17705  
thr hom: homoserine dehydrogenase Archaeoglobus veneficus SNP6 ARCVE_RS07875 ARCVE_RS06785  
thr hom: homoserine dehydrogenase Ferroglobus placidus DSM 10642 FERP_RS00305 FERP_RS04025  
thr hom: homoserine dehydrogenase Halococcus hamelinensis 100A6 C447_RS05685  
thr hom: homoserine dehydrogenase Haloferax volcanii DS2 C498_RS16345 C498_RS15195  
thr hom: homoserine dehydrogenase Methanococcus aeolicus Nankai-3 MAEO_RS06135 MAEO_RS03365  
thr hom: homoserine dehydrogenase Methanococcus maripaludis C5 MMARC5_RS08730 MMARC5_RS02925  
thr hom: homoserine dehydrogenase Methanosarcina acetivorans C2A MA_RS13380 MA_RS00690  
thr hom: homoserine dehydrogenase Methanosarcina mazei Go1 MM_RS14055 MM_RS07335  
thr hom: homoserine dehydrogenase Methanospirillum lacunae Ki8-1 DK846_RS16110 DK846_RS15330  
thr hom: homoserine dehydrogenase Nitrosopumilus maritimus SCM1 NMAR_RS03730 NMAR_RS09380  
thr hom: homoserine dehydrogenase Pyrolobus fumarii 1A PYRFU_RS06440  
thr hom: homoserine dehydrogenase Roseburia faecis M72 M72_RS01920 M72_RS09220  
thr thrB: homoserine kinase Acidimicrobium ferrooxidans DSM 10331 AFER_RS03340 AFER_RS01155  
thr thrB: homoserine kinase Allochromatium vinosum DSM 180 ALVIN_RS15260  
thr thrB: homoserine kinase Anaerobutyricum hallii DSM 3353 EUBHAL_RS01140  
thr thrB: homoserine kinase Cereibacter sphaeroides ATCC 17029 RSPH17029_RS07480  
thr thrB: homoserine kinase Desulfatibacillum aliphaticivorans DSM 15576 G491_RS0116465  
thr thrB: homoserine kinase Dinoroseobacter shibae DFL-12 Dshi_1609  
thr thrB: homoserine kinase Frankia alni ACN14a FRAAL_RS25905  
thr thrB: homoserine kinase Halorhodospira halophila SL1 HHAL_RS13615  
thr thrB: homoserine kinase Methylococcus capsulatus str. Bath MCA_RS01625  
thr thrB: homoserine kinase Methylohalobius crimeensis 10Ki H035_RS0111500  
thr thrB: homoserine kinase Methylomonas methanica MC09 METME_RS02095  
thr thrB: homoserine kinase Methylosarcina fibrata AML-C10 A3OW_RS0105720  
thr thrB: homoserine kinase Methylovulum miyakonense HT12 METMI_RS0114300  
thr thrB: homoserine kinase Oleispira antarctica RB-8 OLEAN_RS00180 OLEAN_RS18425  
thr thrB: homoserine kinase Phaeobacter inhibens BS107 PGA1_c14090  
thr thrB: homoserine kinase Roseburia faecis M72 M72_RS15390  
thr thrB: homoserine kinase Sedimenticola selenatireducens DSM 17993 A3GO_RS0103785  
thr thrB: homoserine kinase Sulfuritalea hydrogenivorans sk43H DSM 22779 SUTH_RS02930  
thr thrB: homoserine kinase Thioalkalivibrio denitrificans ALJD B1C78_RS16900 B1C78_RS14165  
thr thrB: homoserine kinase Thioalkalivibrio halophilus HL17 B1A74_RS09290  
thr thrB: homoserine kinase Thioalkalivibrio paradoxus ARh 1 THITH_RS14415  
thr thrB: homoserine kinase Thioalkalivibrio thiocyanodenitrificans ARhD 1 THITHI_RS0111425 THITHI_RS0109475  
thr thrB: homoserine kinase Thiohalomonas denitrificans HLD2 BLP65_RS14485  
thr thrB: homoserine kinase Thiothrix lacustris DSM 21227 Q394_RS0111245 spurious
trp IGPS: indole-3-glycerol phosphate synthase Denitrovibrio acetiphilus DSM 12809 DACET_RS05910  
trp IGPS: indole-3-glycerol phosphate synthase Desulfitobacterium hafniense DCB-2 DHAF_RS21825 DHAF_RS22210  
trp IGPS: indole-3-glycerol phosphate synthase Hippea alviniae EP5-r G415_RS0107005  
trp IGPS: indole-3-glycerol phosphate synthase Methanobacterium lacus AL-21 METBO_RS10110  
trp IGPS: indole-3-glycerol phosphate synthase Nitrosopumilus maritimus SCM1 NMAR_RS04895  
trp IGPS: indole-3-glycerol phosphate synthase Persephonella marina EX-H1 PERMA_RS04655  
trp IGPS: indole-3-glycerol phosphate synthase Pyrolobus fumarii 1A PYRFU_RS06835  
trp IGPS: indole-3-glycerol phosphate synthase Steroidobacter denitrificans DSM 18526 ACG33_RS14855  
trp PRAI: phosphoribosylanthranilate isomerase Anaerobutyricum hallii DSM 3353 EUBHAL_RS08770 EUBHAL_RS08765  
trp PRAI: phosphoribosylanthranilate isomerase Aquimarina longa SW024 N456_RS05770 N456_RS17095  
trp PRAI: phosphoribosylanthranilate isomerase Arcobacter nitrofigilis DSM 7299 ARNIT_RS03610 ARNIT_RS10710  
trp PRAI: phosphoribosylanthranilate isomerase Calditerrivibrio nitroreducens DSM 19672 CALNI_RS09815 CALNI_RS10855  
trp PRAI: phosphoribosylanthranilate isomerase Chlorobaculum tepidum TLS AYT24_RS02300 AYT24_RS03345  
trp PRAI: phosphoribosylanthranilate isomerase Chlorobium phaeobacteroides BS1 Cphamn1_0475 Cphamn1_1642  
trp PRAI: phosphoribosylanthranilate isomerase Clostridium kluyveri DSM 555 CKL_RS06395 CKL_RS06290  
trp PRAI: phosphoribosylanthranilate isomerase Clostridium tyrobutyricum FAM22553 PN53_RS00690 PN53_RS11025  
trp PRAI: phosphoribosylanthranilate isomerase Crocosphaera subtropica ATCC 51142 CCE_RS19555 CCE_RS04745  
trp PRAI: phosphoribosylanthranilate isomerase Denitrovibrio acetiphilus DSM 12809 DACET_RS14095 DACET_RS05915  
trp PRAI: phosphoribosylanthranilate isomerase Hippea alviniae EP5-r G415_RS0100270 G415_RS0107010  
trp PRAI: phosphoribosylanthranilate isomerase Maridesulfovibrio bastinii DSM 16055 G496_RS0118080 G496_RS0100810  
trp PRAI: phosphoribosylanthranilate isomerase Methanobacterium lacus AL-21 METBO_RS09670 METBO_RS10105  
trp PRAI: phosphoribosylanthranilate isomerase Methanosarcina acetivorans C2A MA_RS01175 MA_RS15670  
trp PRAI: phosphoribosylanthranilate isomerase Methanosarcina mazei Go1 MM_RS07770 MM_RS14625  
trp PRAI: phosphoribosylanthranilate isomerase Methanospirillum lacunae Ki8-1 DK846_RS02885 DK846_RS11325  
trp PRAI: phosphoribosylanthranilate isomerase Methanothermobacter thermautotrophicus str. Delta H MTH_RS03970 MTH_RS07940  
trp PRAI: phosphoribosylanthranilate isomerase Nitrosopumilus maritimus SCM1 NMAR_RS08320 NMAR_RS04895  
trp PRAI: phosphoribosylanthranilate isomerase Nostoc punctiforme PCC 73102 ATCC 29133; PCC 73102 NPUN_RS00270 NPUN_RS08670  
trp PRAI: phosphoribosylanthranilate isomerase Persephonella marina EX-H1 PERMA_RS02510 PERMA_RS08165  
trp PRAI: phosphoribosylanthranilate isomerase Prosthecochloris aestuarii DSM 271 PAES_RS02210 PAES_RS04015  
trp PRAI: phosphoribosylanthranilate isomerase Pyrolobus fumarii 1A PYRFU_RS07130 PYRFU_RS03015  
trp PRAI: phosphoribosylanthranilate isomerase Roseburia faecis M72 M72_RS16045 M72_RS16050  
trp PRAI: phosphoribosylanthranilate isomerase Steroidobacter denitrificans DSM 18526 ACG33_RS07630 ACG33_RS14850  
trp PRAI: phosphoribosylanthranilate isomerase Sulfurihydrogenibium azorense Az-Fu1 SULAZ_RS07545 SULAZ_RS00435  
trp PRAI: phosphoribosylanthranilate isomerase Sulfurihydrogenibium subterraneum DSM 15120 Q385_RS0108120 Q385_RS0103945  
trp PRAI: phosphoribosylanthranilate isomerase Thermodesulforhabdus norvegica DSM 9990 BM091_RS05045 BM091_RS08350  
trp PRAI: phosphoribosylanthranilate isomerase Trichodesmium erythraeum IMS101 Annotated Metagenome-Assembled Genome Ga0074568_114569 Ga0074568_114362  
trp PRAI: phosphoribosylanthranilate isomerase Trichormus variabilis ATCC 29413 AVA_RS17065 AVA_RS12855  
trp trpA: indoleglycerol phosphate aldolase Pyrolobus fumarii 1A spurious
trp trpE: anthranilate synthase subunit TrpE Arcobacter nitrofigilis DSM 7299 ARNIT_RS04640 ARNIT_RS13865  
trp trpE: anthranilate synthase subunit TrpE Calditerrivibrio nitroreducens DSM 19672 CALNI_RS04885 CALNI_RS09730  
trp trpE: anthranilate synthase subunit TrpE Denitrovibrio acetiphilus DSM 12809 DACET_RS05895  
trp trpE: anthranilate synthase subunit TrpE Desulfitobacterium hafniense DCB-2 DHAF_RS21850 DHAF_RS22210  
trp trpE: anthranilate synthase subunit TrpE Kyrpidia tusciae DSM 2912 BTUS_RS09570 BTUS_RS05600  
trp trpE: anthranilate synthase subunit TrpE Methanospirillum lacunae Ki8-1 DK846_RS11345  
trp trpE: anthranilate synthase subunit TrpE Nocardioides dokdonensis FR1436 I601_RS03910 I601_RS05290  
trp trpE: anthranilate synthase subunit TrpE Nocardiopsis lucentensis DSM 44048 D471_RS0103705 D471_RS0104620  
tyr aro-dehydr: arogenate dehydrogenase Haloglycomyces albus DSM 45210 HALAL_RS0106280  
tyr cmutase: chorismate mutase Clostridium acetobutylicum ATCC 824 CA_RS04760 CA_RS16245  
tyr pre-dehydr: prephenate dehydrogenase Acidimicrobium ferrooxidans DSM 10331 AFER_RS11020  
tyr pre-dehydr: prephenate dehydrogenase Acidithiobacillus ferrooxidans ATCC 23270 AFE_RS04225 AFE_RS04210  
tyr pre-dehydr: prephenate dehydrogenase Anaerobutyricum hallii DSM 3353 EUBHAL_RS12050  
tyr pre-dehydr: prephenate dehydrogenase Aquimarina longa SW024 N456_RS09255  
tyr pre-dehydr: prephenate dehydrogenase Arcobacter nitrofigilis DSM 7299 ARNIT_RS08615  
tyr pre-dehydr: prephenate dehydrogenase Calditerrivibrio nitroreducens DSM 19672 CALNI_RS00455 CALNI_RS00440  
tyr pre-dehydr: prephenate dehydrogenase Caminibacter mediatlanticus TB-2 CMTB2_RS06045 CMTB2_RS03830  
tyr pre-dehydr: prephenate dehydrogenase Carboxydothermus pertinax Ug1 cpu_RS09540  
tyr pre-dehydr: prephenate dehydrogenase Chlorobaculum parvum NCIB 8327 CPAR_RS10095 spurious
tyr pre-dehydr: prephenate dehydrogenase Chlorobaculum tepidum TLS AYT24_RS00415 spurious
tyr pre-dehydr: prephenate dehydrogenase Chlorobium limicola DSM 245 CLIM_RS12075 spurious
tyr pre-dehydr: prephenate dehydrogenase Chlorobium phaeobacteroides BS1 Cphamn1_2431 spurious
tyr pre-dehydr: prephenate dehydrogenase Clostridium acetobutylicum ATCC 824 CA_RS04765  
tyr pre-dehydr: prephenate dehydrogenase Clostridium kluyveri DSM 555 CKL_RS03850  
tyr pre-dehydr: prephenate dehydrogenase Clostridium tyrobutyricum FAM22553 PN53_RS02435  
tyr pre-dehydr: prephenate dehydrogenase Dehalococcoides mccartyi 195 DET_RS02500 spurious
tyr pre-dehydr: prephenate dehydrogenase Denitrovibrio acetiphilus DSM 12809 DACET_RS14915 DACET_RS14930  
tyr pre-dehydr: prephenate dehydrogenase Desulfacinum hydrothermale DSM 13146 B9A12_RS02865 B9A12_RS07670  
tyr pre-dehydr: prephenate dehydrogenase Desulfacinum infernum DSM 9756 BUB04_RS02635 BUB04_RS01735  
tyr pre-dehydr: prephenate dehydrogenase Desulfarculus baarsii DSM 2075 DEBA_RS02390 DEBA_RS02395  
tyr pre-dehydr: prephenate dehydrogenase Desulfatibacillum aliphaticivorans DSM 15576 G491_RS31305 G491_RS0117450  
tyr pre-dehydr: prephenate dehydrogenase Desulfatiglans anilini DSM 4660 H567_RS22295 H567_RS0100660  
tyr pre-dehydr: prephenate dehydrogenase Desulfitobacterium hafniense DCB-2 DHAF_RS16940  
tyr pre-dehydr: prephenate dehydrogenase Desulfobacca acetoxidans DSM 11109 DESAC_RS13370  
tyr pre-dehydr: prephenate dehydrogenase Desulfogranum mediterraneum DSM 13871 G494_RS0101895  
tyr pre-dehydr: prephenate dehydrogenase Desulforamulus ruminis DSM 2154 DESRU_RS14955  
tyr pre-dehydr: prephenate dehydrogenase Desulfoscipio geothermicus DSM 3669 BM299_RS01580  
tyr pre-dehydr: prephenate dehydrogenase Desulfotalea psychrophila LSv54 DP_RS11090  
tyr pre-dehydr: prephenate dehydrogenase Frankia alni ACN14a FRAAL_RS09830  
tyr pre-dehydr: prephenate dehydrogenase Heliomicrobium modesticaldum Ice1 Ice1; ATCC 51547 HM1_RS08660  
tyr pre-dehydr: prephenate dehydrogenase Hydrogenovibrio kuenenii DSM 12350 N745_RS0105260 N745_RS0105250  
tyr pre-dehydr: prephenate dehydrogenase Leptospirillum ferrooxidans C2-3 LFE_RS05280 LFE_RS05290  
tyr pre-dehydr: prephenate dehydrogenase Methanococcus aeolicus Nankai-3 MAEO_RS05160  
tyr pre-dehydr: prephenate dehydrogenase Methanospirillum lacunae Ki8-1 DK846_RS01970  
tyr pre-dehydr: prephenate dehydrogenase Nitratifractor salsuginis DSM 16511 NITSA_RS01440 NITSA_RS01510  
tyr pre-dehydr: prephenate dehydrogenase Nitratiruptor tergarcus DSM 16512 B8779_RS04360 B8779_RS04265  
tyr pre-dehydr: prephenate dehydrogenase Nitriliruptor alkaliphilus DSM 45188 NITAL_RS17220  
tyr pre-dehydr: prephenate dehydrogenase Nitrosopumilus maritimus SCM1 NMAR_RS02920  
tyr pre-dehydr: prephenate dehydrogenase Nocardioides dokdonensis FR1436 I601_RS15320  
tyr pre-dehydr: prephenate dehydrogenase Nocardiopsis lucentensis DSM 44048 D471_RS0102780  
tyr pre-dehydr: prephenate dehydrogenase Oleispira antarctica RB-8 OLEAN_RS07045 OLEAN_RS07035  
tyr pre-dehydr: prephenate dehydrogenase Prosthecochloris aestuarii DSM 271 PAES_RS10770  
tyr pre-dehydr: prephenate dehydrogenase Pseudarthrobacter sulfonivorans Ar51 AU252_RS02695  
tyr pre-dehydr: prephenate dehydrogenase Pyrolobus fumarii 1A PYRFU_RS07240  
tyr pre-dehydr: prephenate dehydrogenase Roseburia faecis M72 M72_RS07670  
tyr pre-dehydr: prephenate dehydrogenase Steroidobacter denitrificans DSM 18526 ACG33_RS03230 ACG33_RS07095 spurious
tyr pre-dehydr: prephenate dehydrogenase Sulfuricurvum kujiense DSM 16994 SULKU_RS02200 SULKU_RS09630  
tyr pre-dehydr: prephenate dehydrogenase Sulfurimonas denitrificans DSM 1251 SUDEN_RS03455  
tyr pre-dehydr: prephenate dehydrogenase Thermoanaerobacter kivui LKT-1 TKV_RS05230  
tyr pre-dehydr: prephenate dehydrogenase Thermodesulforhabdus norvegica DSM 9990 BM091_RS08660 BM091_RS03430  
tyr pre-dehydr: prephenate dehydrogenase Thermus aquaticus YT-1 BVI061214_RS07370  
tyr pre-dehydr: prephenate dehydrogenase Thiohalospira halophila DSM 15071 HL 3 spurious
tyr tyrB: tyrosine aminotransferase Maridesulfovibrio zosterae DSM 11974 H589_RS0114540 H589_RS0113385  
tyr tyrB: tyrosine aminotransferase Nitrosopumilus maritimus SCM1 NMAR_RS01310 NMAR_RS02925  
tyr tyrB: tyrosine aminotransferase Pyrolobus fumarii 1A PYRFU_RS08035 PYRFU_RS02975  
val ilvC: 2-hydroxy-3-ketol-acid reductoisomerase Herbaspirillum autotrophicum IAM 14942 AKL27_RS26800 AKL27_RS09680  
val ilvC: 2-hydroxy-3-ketol-acid reductoisomerase Methylobacterium nodulans ORS 2060 spurious
val ilvD: dihydroxy-acid dehydratase Desulfotalea psychrophila LSv54 spurious
val ilvD: dihydroxy-acid dehydratase Desulfovibrio oxyclinae DSM 11498  
val ilvE: valine transaminase Nostoc punctiforme PCC 73102 ATCC 29133; PCC 73102 NPUN_RS09855 NPUN_RS03530  
val ilvE: valine transaminase Pyrolobus fumarii 1A PYRFU_RS08035  
val ilvE: valine transaminase Trichormus variabilis ATCC 29413 AVA_RS05535 AVA_RS10755  
val ilvH: acetolactate/acetohydroxybutanoate synthase regulatory subunit Brevundimonas sp. GW460-12-10-14-LB2 A4249_RS10015  
val ilvH: acetolactate/acetohydroxybutanoate synthase regulatory subunit Pyrolobus fumarii 1A PYRFU_RS08325  
val ilvI: acetolactate/acetohydroxybutanoate synthase catalytic subunit Nocardiopsis lucentensis DSM 44048 D471_RS0116105 spurious

Confidence: high confidence medium confidence low confidence
? – known gap: despite the lack of a good candidate for this step, this organism (or a related organism) performs the pathway

This GapMind analysis is from Jul 25 2024. The underlying query database was built on Jul 25 2024.

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About GapMind

Each pathway is defined by a set of rules based on individual steps or genes. Candidates for each step are identified by using ublast (a fast alternative to protein BLAST) against a database of manually-curated proteins (most of which are experimentally characterized) or by using HMMer with enzyme models (usually from TIGRFam). Ublast hits may be split across two different proteins.

A candidate for a step is "high confidence" if either:

where "other" refers to the best ublast hit to a sequence that is not annotated as performing this step (and is not "ignored").

Otherwise, a candidate is "medium confidence" if either:

Other blast hits with at least 50% coverage are "low confidence."

Steps with no high- or medium-confidence candidates may be considered "gaps." For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, there is a complete high-confidence catabolic pathway (including a transporter) just 38% of the time, and there is a complete medium-confidence pathway 63% of the time. Gaps may be due to:

GapMind relies on the predicted proteins in the genome and does not search the six-frame translation. In most cases, you can search the six-frame translation by clicking on links to Curated BLAST for each step definition (in the per-step page).

For more information, see:

If you notice any errors or omissions in the step descriptions, or any questionable results, please let us know

by Morgan Price, Arkin group, Lawrence Berkeley National Laboratory