Alignments for a candidate for metH in Shewanella amazonensis SB2B

GapMind for Amino acid biosynthesis

Alignments for a candidate for metH in Shewanella amazonensis SB2B

Align methionine synthase; EC 2.1.1.13 (characterized)
to candidate 6936570 Sama_0758 B12-dependent methionine synthase (RefSeq)

Query= CharProtDB::CH_090726
         (1227 letters)



>FitnessBrowser__SB2B:6936570
          Length = 1246

 Score = 1643 bits (4255), Expect = 0.0
 Identities = 820/1232 (66%), Positives = 973/1232 (78%), Gaps = 8/1232 (0%)

Query: 3    SKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSKPE 62
            S+ ++L   L+ RIL+LDG MGTMIQ ++L E  +RG RFADW CD+KGNNDLLVL++PE
Sbjct: 16   SRQQRLNEDLSTRILILDGAMGTMIQGHKLEEEHYRGSRFADWHCDVKGNNDLLVLTQPE 75

Query: 63   VIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTART 122
            +I  IH  Y  AGADIIETNTFN+TT+AMADY M+SLSAEIN   A++AR  ADE  A+T
Sbjct: 76   IIKGIHREYLLAGADIIETNTFNATTVAMADYDMQSLSAEINLVGARIAREVADEVEAQT 135

Query: 123  PEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLVAAYRESTKALVEGGADLILIET 182
               PRYVAGVLGPTNRT SISPDVNDP +RNI FD LV AYREST AL+EGGAD+I++ET
Sbjct: 136  GI-PRYVAGVLGPTNRTCSISPDVNDPGYRNIHFDDLVTAYRESTAALIEGGADIIMVET 194

Query: 183  VFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALT 242
            +FDTLNAKAA+FA+++ F+ +G+ LP+MISGTITDASGRTL+GQTTEAFYNSLRH + ++
Sbjct: 195  IFDTLNAKAALFAIESIFDEVGLRLPVMISGTITDASGRTLTGQTTEAFYNSLRHIKPIS 254

Query: 243  FGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAQAG 302
             GLNCALGP ELR YV+ELSRI+ECYV+AHPNAGLPN FG YD     MA  I +WA  G
Sbjct: 255  MGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPKEMADIIVQWAIEG 314

Query: 303  FLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPEIPVACRLSGLEPLNIGEDSLFVNVGER 362
             LNIVGGCCGTTP HI  +  AVE  APRKLPE+PVACRL+GLEPL I  DSLFVNVGER
Sbjct: 315  MLNIVGGCCGTTPDHIRVIREAVEKHAPRKLPELPVACRLAGLEPLTISADSLFVNVGER 374

Query: 363  TNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLIAG 422
            TNVTGSAKF +LIKE +Y  ALDVAR QVENGAQIIDINMDEGMLD E  M  FLNL+A 
Sbjct: 375  TNVTGSAKFLKLIKEGQYETALDVARDQVENGAQIIDINMDEGMLDGEEVMTTFLNLVAS 434

Query: 423  EPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAVVV 482
            EP+I++VPIMIDSSKW+VIE GLKC+QGK IVNSIS+KEG   FI  A L++RYGAA ++
Sbjct: 435  EPEISKVPIMIDSSKWEVIEAGLKCVQGKCIVNSISLKEGEAKFIEQATLVKRYGAAAII 494

Query: 483  MAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDF 542
            MAFDE GQADTRARKIEIC RAY+IL ++VGFPPEDIIFDPNIFAVATGIEEH+NYA DF
Sbjct: 495  MAFDETGQADTRARKIEICTRAYRILVDKVGFPPEDIIFDPNIFAVATGIEEHDNYAVDF 554

Query: 543  IGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQL 602
            I A  DIK  LPHA+ISGGVSNVSFSFRGN+PVREAIHAVFLY+AI+ GMDMGIVNAGQL
Sbjct: 555  IEAVRDIKATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIKEGMDMGIVNAGQL 614

Query: 603  AIYDDLPAELRDAVEDVILN-----RRDDGTERLLELAEKYRGSKTDDTANAQQAEWRSW 657
            AIYDD+PAEL++ VE V+LN          TE+LLE+AEKYRG         +  +WRS 
Sbjct: 615  AIYDDIPAELKERVEAVVLNLPCPVEDSTNTEQLLEIAEKYRGGGGSGAGKKEDLQWRSL 674

Query: 658  EVNKRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQ 717
             VNKRLE++LVKGITEFI+ DTEEARQQATRP++VIEGPLMDGMNVVGDLFGEGKMFLPQ
Sbjct: 675  PVNKRLEHALVKGITEFIDADTEEARQQATRPLDVIEGPLMDGMNVVGDLFGEGKMFLPQ 734

Query: 718  VVKSARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEI 777
            VVKSARVMK+AVAYL PFIEA K  G++NGK+++ TVKGDVHDIGKNIVGVVL CN YE+
Sbjct: 735  VVKSARVMKKAVAYLNPFIEAEKVAGQSNGKVLMVTVKGDVHDIGKNIVGVVLACNGYEV 794

Query: 778  VDLGVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATT 837
            +DLGVMVP EKI+  AK+   D+IG+SGLITPSLDEMV+  K  ER+G T+P +IGGAT 
Sbjct: 795  IDLGVMVPVEKIVEVAKKEQVDIIGMSGLITPSLDEMVHNVKTFEREGLTLPAIIGGATC 854

Query: 838  SKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRK 897
            SK HTAVKI  +Y    +Y+ +ASR V +V+ L+++  R   +  T  EY+ +R +   +
Sbjct: 855  SKIHTAVKIAPHYPHGAIYIPDASRAVPMVSKLINEETRAATIKATYDEYDVMREKRLSQ 914

Query: 898  KPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVE-ASIETLRNYIDWTPFFMTWSL 956
              R   +++EAAR+N    DW  Y P V ++LG+Q  E   ++ L + IDWTPFF  W L
Sbjct: 915  AKRKEIISIEAARENRCQLDWANYQPKVPNKLGIQVFEDYPLDDLVDRIDWTPFFRAWEL 974

Query: 957  AGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVG-DDIEIYR 1015
             G +PRILEDEVVG EA++LF DA  ML  +  EK L  +GV+GLFPAN V  DDIE+Y 
Sbjct: 975  HGHFPRILEDEVVGEEARKLFADAKAMLQTIIDEKWLTAKGVIGLFPANTVNHDDIELYT 1034

Query: 1016 DETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADA 1075
            DE+R+ V+  +HHLR Q E+ G  N+CL+DFVAPK SG  DY G FAV  G   D     
Sbjct: 1035 DESRSQVLMTTHHLRMQIERVGNDNFCLSDFVAPKDSGVVDYTGGFAVCAGHGIDEHLAR 1094

Query: 1076 FEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRP 1135
            FEA HDDYN IM+K LADRLAEAFAE +HERVRK +WGYA +ENL NE LIRE Y+GIRP
Sbjct: 1095 FEANHDDYNAIMLKVLADRLAEAFAERMHERVRKEFWGYASDENLDNEALIREKYRGIRP 1154

Query: 1136 APGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQI 1195
            APGYPACP+HTEK  +W+LL+  +   + +TESFAM+P A+VSGWYF+HP+++Y+ V  I
Sbjct: 1155 APGYPACPDHTEKGLLWDLLKPNECIDLNITESFAMYPTAAVSGWYFAHPEARYFGVTNI 1214

Query: 1196 QRDQVEDYARRKGMSVTEVERWLAPNLGYDAD 1227
             RDQVEDYARRKGM+V E E+WLAP L YD +
Sbjct: 1215 GRDQVEDYARRKGMTVAETEKWLAPILDYDPE 1246


Lambda     K      H
   0.318    0.134    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 3781
Number of extensions: 145
Number of successful extensions: 5
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 1227
Length of database: 1246
Length adjustment: 48
Effective length of query: 1179
Effective length of database: 1198
Effective search space:  1412442
Effective search space used:  1412442
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)

Align candidate 6936570 Sama_0758 (B12-dependent methionine synthase (RefSeq))
to HMM TIGR02082 (metH: methionine synthase (EC 2.1.1.13))

# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.3.1 (Jul 2020); http://hmmer.org/
# Copyright (C) 2020 Howard Hughes Medical Institute.
# Freely distributed under the BSD open source license.
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  ../tmp/path.aa/TIGR02082.hmm
# target sequence database:        /tmp/gapView.30457.genome.faa
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TIGR02082  [M=1182]
Accession:   TIGR02082
Description: metH: methionine synthase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence                         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------                         -----------
          0 1780.0   0.0          0 1779.8   0.0    1.0  1  lcl|FitnessBrowser__SB2B:6936570  Sama_0758 B12-dependent methioni


Domain annotation for each sequence (and alignments):
>> lcl|FitnessBrowser__SB2B:6936570  Sama_0758 B12-dependent methionine synthase (RefSeq)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ! 1779.8   0.0         0         0       2    1182 .]      26    1211 ..      25    1211 .. 0.98

  Alignments for each domain:
  == domain 1  score: 1779.8 bits;  conditional E-value: 0
                         TIGR02082    2 nkrilvlDGamGtqlqsanLteadFrge.eadlarelkGnndlLnltkPeviaaihrayfeaGaDivetntFnst 75  
                                        + ril+lDGamGt++q ++L+e+++rg+ +ad+++++kGnndlL+lt+Pe+i+ ihr+y+ aGaDi+etntFn+t
  lcl|FitnessBrowser__SB2B:6936570   26 STRILILDGAMGTMIQGHKLEEEHYRGSrFADWHCDVKGNNDLLVLTQPEIIKGIHREYLLAGADIIETNTFNAT 100 
                                        78************************************************************************* PP

                         TIGR02082   76 eialadYdledkayelnkkaaklarevadeftltpekkRfvaGslGPtnklatlspdverpefrnvtydelvdaY 150 
                                        ++a+adYd++++++e+n  +a++arevade++ ++  +R+vaG+lGPtn++ ++spdv++p++rn+++d+lv aY
  lcl|FitnessBrowser__SB2B:6936570  101 TVAMADYDMQSLSAEINLVGARIAREVADEVEAQTGIPRYVAGVLGPTNRTCSISPDVNDPGYRNIHFDDLVTAY 175 
                                        *************************************************************************** PP

                         TIGR02082  151 keqvkglldGGvDllLietvfDtlnakaalfaveevfeekgrelPilisgvivdksGrtLsGqtleaflasleha 225 
                                        +e++ +l++GG+D++++et+fDtlnakaalfa+e++f+e g +lP++isg+i+d+sGrtL+Gqt+eaf++sl+h 
  lcl|FitnessBrowser__SB2B:6936570  176 RESTAALIEGGADIIMVETIFDTLNAKAALFAIESIFDEVGLRLPVMISGTITDASGRTLTGQTTEAFYNSLRHI 250 
                                        *************************************************************************** PP

                         TIGR02082  226 eililGLnCalGadelrefvkelsetaealvsviPnaGLPnalgeYdltpeelakalkefaeegllnivGGCCGt 300 
                                        + +++GLnCalG++elr++v+els+++e++vs++PnaGLPn++g Yd+tp+e+a ++ ++a eg+lnivGGCCGt
  lcl|FitnessBrowser__SB2B:6936570  251 KPISMGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPKEMADIIVQWAIEGMLNIVGGCCGT 325 
                                        *************************************************************************** PP

                         TIGR02082  301 tPehiraiaeavkdikprkrqeleeksvlsglealkiaqessfvniGeRtnvaGskkfrklikaedyeealkiak 375 
                                        tP+hir i eav++ +prk +el+ +++l+gle+l+i+ +s fvn+GeRtnv+Gs+kf klik+++ye al++a+
  lcl|FitnessBrowser__SB2B:6936570  326 TPDHIRVIREAVEKHAPRKLPELPVACRLAGLEPLTISADSLFVNVGERTNVTGSAKFLKLIKEGQYETALDVAR 400 
                                        *************************************************************************** PP

                         TIGR02082  376 qqveeGaqilDinvDevllDgeadmkkllsllasepdiakvPlmlDssefevleaGLkviqGkaivnsislkdGe 450 
                                        +qve+Gaqi+Din+De++lDge+ m+++l+l+asep+i+kvP+m+Dss++ev+eaGLk++qGk+ivnsislk+Ge
  lcl|FitnessBrowser__SB2B:6936570  401 DQVENGAQIIDINMDEGMLDGEEVMTTFLNLVASEPEISKVPIMIDSSKWEVIEAGLKCVQGKCIVNSISLKEGE 475 
                                        *************************************************************************** PP

                         TIGR02082  451 erFlekaklikeyGaavvvmafDeeGqartadkkieiakRayklltekvgfppediifDpniltiatGieehdry 525 
                                        ++F+e+a l+k+yGaa+++mafDe Gqa+t+++kiei++Ray++l++kvgfppediifDpni+++atGieehd+y
  lcl|FitnessBrowser__SB2B:6936570  476 AKFIEQATLVKRYGAAAIIMAFDETGQADTRARKIEICTRAYRILVDKVGFPPEDIIFDPNIFAVATGIEEHDNY 550 
                                        *************************************************************************** PP

                         TIGR02082  526 aidfieaireikeelPdakisgGvsnvsFslrgndavRealhsvFLyeaikaGlDmgivnagklavyddidkelr 600 
                                        a+dfiea+r+ik +lP+a isgGvsnvsFs+rgn++vRea+h+vFLy+aik G+Dmgivnag+la+yddi++el+
  lcl|FitnessBrowser__SB2B:6936570  551 AVDFIEAVRDIKATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIKEGMDMGIVNAGQLAIYDDIPAELK 625 
                                        *************************************************************************** PP

                         TIGR02082  601 evvedlildrr.....reatekLlelaelykgtkeksskeaqeaewrnlpveeRLeralvkGeregieedleear 670 
                                        e ve ++l+       + +te+Lle+ae+y+g   + + +++  +wr+lpv++RLe+alvkG++e+i++d+eear
  lcl|FitnessBrowser__SB2B:6936570  626 ERVEAVVLNLPcpvedSTNTEQLLEIAEKYRGGGGSGAGKKEDLQWRSLPVNKRLEHALVKGITEFIDADTEEAR 700 
                                        *********7666665999***************9999999999******************************* PP

                         TIGR02082  671 kklkapleiiegpLldGmkvvGdLFGsGkmfLPqvvksarvmkkavayLePylekekeedkskGkivlatvkGDv 745 
                                        +++++pl++iegpL+dGm+vvGdLFG+GkmfLPqvvksarvmkkavayL+P++e+ek + +s+Gk+++ tvkGDv
  lcl|FitnessBrowser__SB2B:6936570  701 QQATRPLDVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLNPFIEAEKVAGQSNGKVLMVTVKGDV 775 
                                        *************************************************************************** PP

                         TIGR02082  746 hDiGknivdvvLscngyevvdlGvkvPvekileaakkkkaDviglsGLivksldemvevaeemerrgvkiPlllG 820 
                                        hDiGkniv+vvL+cngyev+dlGv+vPveki+e+akk++ D+ig+sGLi++sldemv++++ +er+g+++P ++G
  lcl|FitnessBrowser__SB2B:6936570  776 HDIGKNIVGVVLACNGYEVIDLGVMVPVEKIVEVAKKEQVDIIGMSGLITPSLDEMVHNVKTFEREGLTLPAIIG 850 
                                        *************************************************************************** PP

                         TIGR02082  821 GaalskahvavkiaekYkgevvyvkdaseavkvvdkllsekkkaeelekikeeyeeirekfgekkeklialseka 895 
                                        Ga+ sk h+avkia++Y    +y  das+av +v+kl++e+++a+ ++++ +ey+ +rek  ++ ++++ +s++a
  lcl|FitnessBrowser__SB2B:6936570  851 GATCSKIHTAVKIAPHYPHGAIYIPDASRAVPMVSKLINEETRAATIKATYDEYDVMREKRLSQAKRKEIISIEA 925 
                                        *************************************************************************** PP

                         TIGR02082  896 arkevfaldrsedlevpapkflGtkvleas.ieellkyiDwkalFvqWelrgkypkilkdeleglearklfkdak 969 
                                        ar+++ +ld+  ++++ +p++lG++v+e++ +++l++ iDw+++F +Wel+g++p+il+de++g+earklf+dak
  lcl|FitnessBrowser__SB2B:6936570  926 ARENRCQLDWA-NYQPKVPNKLGIQVFEDYpLDDLVDRIDWTPFFRAWELHGHFPRILEDEVVGEEARKLFADAK 999 
                                        ***********.9************************************************************** PP

                         TIGR02082  970 elldklsaekllrargvvGlfPaqsv.gddieiytdetvsqetkpiatvrekleqlrqqsdrylclaDfiaskes 1043
                                        ++l++++ ek l+a+gv+GlfPa++v +ddie+ytde++sq      t+++ + q+++  + + cl+Df+a+k+s
  lcl|FitnessBrowser__SB2B:6936570 1000 AMLQTIIDEKWLTAKGVIGLFPANTVnHDDIELYTDESRSQVL---MTTHHLRMQIERVGNDNFCLSDFVAPKDS 1071
                                        ************************762699********95544...44444455666666669************ PP

                         TIGR02082 1044 GikDylgallvtaglgaeelakkleakeddydsilvkaladrlaealaellhervRkelwgyaeeenldkedllk 1118
                                        G +Dy g ++v ag g++e   ++ea++ddy++i++k ladrlaea+ae +hervRke+wgya++enld+e l++
  lcl|FitnessBrowser__SB2B:6936570 1072 GVVDYTGGFAVCAGHGIDEHLARFEANHDDYNAIMLKVLADRLAEAFAERMHERVRKEFWGYASDENLDNEALIR 1146
                                        *************************************************************************** PP

                         TIGR02082 1119 erYrGirpafGYpacPdhtekatlleLleaer.iGlklteslalaPeasvsglyfahpeakYfav 1182
                                        e+YrGirpa+GYpacPdhtek  l++Ll++++ i l++tes+a++P+a+vsg+yfahpea+Yf v
  lcl|FitnessBrowser__SB2B:6936570 1147 EKYRGIRPAPGYPACPDHTEKGLLWDLLKPNEcIDLNITESFAMYPTAAVSGWYFAHPEARYFGV 1211
                                        ******************************999******************************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                            1  (1182 nodes)
Target sequences:                          1  (1246 residues searched)
Passed MSV filter:                         1  (1); expected 0.0 (0.02)
Passed bias filter:                        1  (1); expected 0.0 (0.02)
Passed Vit filter:                         1  (1); expected 0.0 (0.001)
Passed Fwd filter:                         1  (1); expected 0.0 (1e-05)
Initial search space (Z):                  1  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.08u 0.03s 00:00:00.11 Elapsed: 00:00:00.10
# Mc/sec: 13.68
//
[ok]

This GapMind analysis is from Apr 09 2024. The underlying query database was built on Apr 09 2024.

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About GapMind

Each pathway is defined by a set of rules based on individual steps or genes. Candidates for each step are identified by using ublast (a fast alternative to protein BLAST) against a database of manually-curated proteins (most of which are experimentally characterized) or by using HMMer with enzyme models (usually from TIGRFam). Ublast hits may be split across two different proteins.

A candidate for a step is "high confidence" if either:

ublast finds a hit to a characterized protein at above 40% identity and 80% coverage, and bits >= other bits+10.
- (Hits to curated proteins without experimental data as to their function are never considered high confidence.)
HMMer finds a hit with 80% coverage of the model, and either other identity < 40 or other coverage < 0.75.

where "other" refers to the best ublast hit to a sequence that is not annotated as performing this step (and is not "ignored").

Otherwise, a candidate is "medium confidence" if either:

ublast finds a hit at above 40% identity and 70% coverage (ignoring otherBits).
ublast finds a hit at above 30% identity and 80% coverage, and bits >= other bits.
HMMer finds a hit (regardless of coverage or other bits).

Other blast hits with at least 50% coverage are "low confidence."

Steps with no high- or medium-confidence candidates may be considered "gaps." For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, there is a complete high-confidence catabolic pathway (including a transporter) just 38% of the time, and there is a complete medium-confidence pathway 63% of the time. Gaps may be due to:

our ignorance of proteins' functions,
omissions in the gene models,
frame-shift errors in the genome sequence, or
the organism lacks the pathway.

GapMind relies on the predicted proteins in the genome and does not search the six-frame translation. In most cases, you can search the six-frame translation by clicking on links to Curated BLAST for each step definition (in the per-step page).

For more information, see:

the paper from 2019 on GapMind for amino acid biosynthesis
the paper from 2022 on GapMind for carbon sources
the source code
instructions for running GapMind on your computer
changes to Amino acid biosynthesis since the publication.

If you notice any errors or omissions in the step descriptions, or any questionable results, please let us know

by Morgan Price, Arkin group, Lawrence Berkeley National Laboratory

GapMind for Amino acid biosynthesis