GapMind for Amino acid biosynthesis

 

L-asparagine biosynthesis

Analysis of pathway asn in 276 genomes

Genome Best path
Acidovorax caeni R-24608 aspS2, gatA, gatB, gatC
Actinokineospora bangkokensis 44EHW aspS2, gatA, gatB, gatC
Actinomyces timonensis 7400942 aspS2, gatA, gatB, gatC
Algiphilus aromaticivorans DG1253 aspS2, gatA, gatB, gatC
Algoriphagus aquaeductus T4 aspS2, gatA, gatB, gatC
Algoriphagus machipongonensis PR1 aspS2, gatA, gatB, gatC
Alicyclobacillus ferrooxydans TC-34 asnB
Alishewanella agri BL06 asnB
Alistipes indistinctus YIT 12060 asnB
Alistipes shahii WAL 8301 asnA
Alkalitalea saponilacus SC/BZ-SP2 asnA
Amantichitinum ursilacus IGB-41 aspS2, gatA, gatB, gatC
Amphibacillus jilinensis Y1 aspS2, gatA, gatB, gatC
Amphritea japonica JAMM 1866 aspS2, gatA, gatB, gatC
Amycolatopsis halophila YIM 93223 aspS2, gatA, gatB, gatC
Amycolatopsis xylanica CPCC 202699 asnB
Aquimarina agarilytica ZC1 aspS2, gatA, gatB, gatC
Aquimarina longa SW024 asnB
Aquimarina macrocephali JAMB N27 asnB
Archaeoglobus sulfaticallidus PM70-1 aspS2, gatA, gatB, gatC
Arcticibacter svalbardensis MN12-7 asnB
Ardenticatena maritima 110S aspS2, gatA, gatB, gatC
Arenimonas metalli CF5-1 asnB
Arenitalea lutea P7-3-5 asnB
Azospirillum humicireducens SgZ-5 aspS2, gatA, gatB, gatC
Azospirillum thiophilum BV-S aspS2, gatA, gatB, gatC
Bacillus altitudinis 41KF2b aspS2, gatA, gatB, gatC
Bacillus coahuilensis m4-4 aspS2, gatA, gatB, gatC
Bacillus cytotoxicus NVH 391-98 aspS2, gatA, gatB, gatC
Bacillus horneckiae 1P01SC aspS2, gatA, gatB, gatC
Bacillus okhensis Kh10-101 aspS2, gatA, gatB, gatC
Bacillus safensis FO-36b aspS2, gatA, gatB, gatC
Bacillus velezensis CBMB205 aspS2, gatA, gatB, gatC
Bacteroides clarus YIT 12056 asnB
Bacteroides faecis MAJ27 asnB
Bacteroides fluxus YIT 12057 asnA
Bacteroides oleiciplenus YIT 12058 asnB
Barnesiella intestinihominis YIT 11860 asnA
Belnapia rosea CPCC 100156 aspS2, gatA, gatB, gatC
Bizionia argentinensis JUB59 asnB
Bradyrhizobium diazoefficiens USDA110 aspS2, gatA, gatB, gatC
Brevibacterium jeotgali SJ5-8 aspS2, gatA, gatB, gatC
Brucella inopinata BO1 aspS2, gatA, gatB, gatC
Brucella microti CCM 4915 aspS2, gatA, gatB, gatC
Bryobacter aggregatus MPL3 asnB
Caldicellulosiruptor hydrothermalis 108 aspS2, gatA, gatB, gatC
Caldicellulosiruptor kronotskyensis 2002 aspS2, gatA, gatB, gatC
Carboxydothermus pertinax Ug1 aspS2, gatA, gatB, gatC
Catellicoccus marimammalium M35/04/3 aspS2, gatA, gatB, gatC
Chromobacterium vaccinii MWU205 aspS2, gatA, gatB, gatC
Chryseobacterium angstadtii KM asnB
Chryseobacterium arthrosphaerae CC-VM-7 asnB
Chryseobacterium viscerum 687B-08 asnB
Cloacibacillus porcorum CL-84 aspS2, gatA, gatB, gatC
Cobetia crustatorum JO1 aspS2, gatA, gatB, gatC
Collimonas arenae Ter10 aspS2, gatA, gatB, gatC
Collimonas pratensis Ter91 aspS2, gatA, gatB, gatC
Collinsella tanakaei YIT 12063 aspS2, gatA, gatB, gatC
Coprobacter fastidiosus NSB1 asnB
Corynebacterium deserti GIMN1.010 aspS2, gatA, gatB, gatC
Corynebacterium frankenforstense ST18 asnB
Corynebacterium lactis RW2-5 aspS2, gatA, gatB, gatC
Croceitalea dokdonensis DOKDO 023 asnB
Cronobacter condimenti 1330 asnB
Cronobacter muytjensii ATCC 51329 asnB
Cronobacter universalis NCTC 9529 asnB
Desulfatitalea tepidiphila S28bF aspS2, gatA, gatB, gatC
Desulfotomaculum hydrothermale Lam5 aspS2, gatA, gatB, gatC
Dethiosulfovibrio salsuginis USBA 82 aspS2, gatA, gatB, gatC
Devosia chinhatensis IPL18 aspS2, gatA, gatB, gatC
Devriesea agamarum IMP2 asnB
Dialister succinatiphilus YIT 11850 aspS2, gatA, gatB, gatC
Dietzia timorensis ID05-A0528 aspS2, gatA, gatB, gatC
Dokdonella koreensis DS-123 aspS2, gatA, gatB, gatC
Domibacillus robiginosus WS 4628 aspS2, gatA, gatB, gatC
Duganella sacchari Sac-22 aspS2, gatA, gatB, gatC
Dyadobacter tibetensis Y620-1 aspS2, gatA, gatB, gatC
Dyella jiangningensis SBZ3-12 asnB
Endozoicomonas montiporae CL-33 aspS2, gatA, gatB, gatC
Enterococcus termitis LMG 8895 aspS2, gatA, gatB, gatC
Enterorhabdus caecimuris B7 aspS2, gatA, gatB, gatC
Epibacterium ulvae U95 aspS2, gatA, gatB, gatC
Erythrobacter gangjinensis K7-2 aspS2, gatA, gatB, gatC
Erythrobacter marinus HWDM-33 aspS2, gatA, gatB, gatC
Ethanoligenens harbinense YUAN-3 aspS2, gatA, gatB, gatC
Fervidicella metallireducens AeB aspS2, gatA, gatB, gatC
Fibrella aestuarina BUZ 2 asnB
Flammeovirga pacifica WPAGA1 aspS2, gatA, gatB, gatC
Flaviramulus ichthyoenteri Th78 asnB
Flavobacterium beibuense F44-8 asnB
Flavobacterium glycines Gm-149 aspS2, gatA, gatB, gatC
Flavobacterium sp. LM5 asnB
Flavobacterium ummariense DS-12 asnB
Frischella perrara PEB0191 asnB
Galbibacter marinus ck-I2-15 asnB
Gallaecimonas xiamenensis 3-C-1 asnB
Geobacter daltonii FRC-32 aspS2, gatA, gatB, gatC
Gillisia marina CBA3202 asnB
Gracilibacillus halophilus YIM-C55.5 asnB
Granulicella mallensis MP5ACTX8 aspS2, gatA, gatB, gatC
Granulicella tundricola MP5ACTX9 aspS2, gatA, gatB, gatC
Hafnia paralvei ATCC 29927 asnB
Haladaptatus cibarius D43 aspS2, gatA, gatB, gatC
Halioglobus japonicus S1-36 aspS2, gatA, gatB, gatC
Halobacillus alkaliphilus FP5 aspS2, gatA, gatB, gatC
Halococcus hamelinensis 100A6 aspS2, gatA, gatB, gatC
Halomonas salina B6 aspS2, gatA, gatB, gatC
Halomonas smyrnensis AAD6 aspS2, gatA, gatB, gatC
Halomonas stevensii S18214 aspS2, gatA, gatB, gatC
Halomonas titanicae BH1 aspS2, gatA, gatB, gatC
Halomonas xinjiangensis TRM 0175 aspS2, gatA, gatB, gatC
Halopiger salifodinae KCY07-B2 aspS2, gatA, gatB, gatC
Halostagnicola larsenii XH-48 aspS2, gatA, gatB, gatC
Haloterrigena daqingensis JX313 aspS2, gatA, gatB, gatC
Herbaspirillum aquaticum IEH 4430 aspS2, gatA, gatB, gatC
Hippea alviniae EP5-r aspS2, gatA, gatB, gatC
Hippea jasoniae Mar08-272r aspS2, gatA, gatB, gatC
Hoeflea phototrophica DFL-43 aspS2, gatA, gatB, gatC
Hyphomicrobium nitrativorans NL23 aspS2, gatA, gatB, gatC
Imtechella halotolerans K1 asnB
Indibacter alkaliphilus LW1 aspS2, gatA, gatB, gatC
Jannaschia aquimarina GSW-M26 aspS2, gatA, gatB, gatC
Jeotgalibacillus soli P9 aspS2, gatA, gatB, gatC
Kangiella geojedonensis YCS-5 asnB
Knoellia flava TL1 asnB
Kocuria flava HO-9041 aspS2, gatA, gatB, gatC
Kocuria turfanensis HO-9042 asnB
Laceyella sediminis RHA1 aspS2, gatA, gatB, gatC
Lacinutrix algicola AKS293 asnB
Lacinutrix himadriensis E4-9a asnB
Lacinutrix mariniflava AKS432 asnB
Lactobacillus curieae CCTCC M 2011381 aspS2, gatA, gatB, gatC
Lactobacillus delbrueckii ZN7a-9 aspS2, gatA, gatB, gatC
Lactobacillus hokkaidonensis LOOC260 aspS2, gatA, gatB, gatC
Lactobacillus oryzae SG293 aspS2, gatA, gatB, gatC
Lactobacillus pobuzihii E100301 aspS2, gatA, gatB, gatC
Lactobacillus shenzhenensis LY-73 aspS2, gatA, gatB, gatC
Lactobacillus silagei IWT126 aspS2, gatA, gatB, gatC
Leeuwenhoekiella blandensis MED217 asnB
Lentibacillus jeotgali Grbi aspS2, gatA, gatB, gatC
Limnohabitans curvus MWH-C5 aspS2, gatA, gatB, gatC
Limnohabitans parvus II-B4 aspS2, gatA, gatB, gatC
Listeria fleischmannii LU2006-1 aspS2, gatA, gatB, gatC
Luteimonas huabeiensis HB2 asnB
Luteipulveratus mongoliensis MN07-A0370 aspS2, gatA, gatB, gatC
Lutibaculum baratangense AMV1 aspS2, gatA, gatB, gatC
Lysobacter daejeonensis GH1-9 asnB
Magnetovibrio blakemorei MV-1 aspS2, gatA, gatB, gatC
Marinicella litoralis KMM 3900 aspS2, gatA, gatB, gatC
Mariniradius saccharolyticus AK6 aspS2, gatA, gatB, gatC
Marinobacter algicola DG893 aspS2, gatA, gatB, gatC
Marinobacter guineae M3B aspS2, gatA, gatB, gatC
Marinobacter psychrophilus 20041 aspS2, gatA, gatB, gatC
Marinomonas arctica 328 aspS2, gatA, gatB, gatC
Marivita geojedonensis DPG-138 aspS2, gatA, gatB, gatC
Martelella endophytica YC6887 aspS2, gatA, gatB, gatC
Megamonas funiformis YIT 11815 aspS2, gatA, gatB, gatC
Mesorhizobium ciceri WSM1271 asnB
Methanobacterium arcticum M2 asnB
Methanobacterium veterum MK4 asnB
Methanocella arvoryzae MRE50 aspS2, gatA, gatB, gatC
Methanococcus aeolicus Nankai-3 aspS2, gatA, gatB, gatC
Methanoculleus horonobensis T10 aspS2, gatA, gatB, gatC
Methanolinea tarda NOBI-1 aspS2, gatA, gatB, gatC
Methanosarcina soligelidi SMA-21 aspS2, gatA, gatB, gatC
Methanospirillum lacunae Ki8-1 aspS2, gatA, gatB, gatC
Methanospirillum stamsii Pt1 aspS2, gatA, gatB, gatC
Methylibium petroleiphilum PM1 aspS2, gatA, gatB, gatC
Methylobacterium gossipiicola Gh-105 aspS2, gatA, gatB, gatC
Methylocapsa aurea KYG aspS2, gatA, gatB, gatC
Methylotenera versatilis 301 aspS2, gatA, gatB, gatC
Microbacterium profundi Shh49 aspS2, gatA, gatB, gatC
Microvirga lotononidis WSM3557 aspS2, gatA, gatB, gatC
Moritella dasanensis ArB 0140 asnB
Mucilaginibacter gossypii Gh-67 aspS2, gatA, gatB, gatC
Mucilaginibacter gossypiicola Gh-48 aspS2, gatA, gatB, gatC
Mucilaginibacter mallensis MP1X4 aspS2, gatA, gatB, gatC
Nafulsella turpanensis ZLM-10 aspS2, gatA, gatB, gatC
Natronomonas moolapensis 8.8.11 aspS2, gatA, gatB, gatC
Nautilia profundicola AmH aspS2, gatA, gatB, gatC
Neiella marina J221 asnB
Neptunomonas antarctica S3-22 aspS2, gatA, gatB, gatC
Nocardioides daejeonensis MJ31 aspS2, gatA, gatB, gatC
Nocardioides dokdonensis FR1436 asnB
Nocardiopsis baichengensis YIM 90130 aspS2, gatA, gatB, gatC
Nocardiopsis gilva YIM 90087 aspS2, gatA, gatB, gatC
Novosphingobium barchaimii LL02 aspS2, gatA, gatB, gatC
Novosphingobium fuchskuhlense FNE08-7 aspS2, gatA, gatB, gatC
Novosphingobium lindaniclasticum LE124 aspS2, gatA, gatB, gatC
Oceanisphaera arctica V1-41 asnB
Ochrobactrum rhizosphaerae PR17 aspS2, gatA, gatB, gatC
Ochrobactrum thiophenivorans DSM 7216 aspS2, gatA, gatB, gatC
Oscillibacter ruminantium GH1 asnB
Paenisporosarcina indica PN2 aspS2, gatA, gatB, gatC
Palaeococcus pacificus DY20341 asnA
Paludibacter propionicigenes WB4 asnB
Pandoraea thiooxydans ATSB16 aspS2, gatA, gatB, gatC
Pantoea rwandensis LMG 26275 asnB
Pedobacter arcticus A12 aspS2, gatA, gatB, gatC
Photobacterium gaetbulicola Gung47 asnB
Photobacterium jeanii R-40508 asnB
Phyllobacterium brassicacearum STM 196 aspS2, gatA, gatB, gatC
Phyllobacterium endophyticum PEPV15 aspS2, gatA, gatB, gatC
Phyllobacterium leguminum ORS 1419 aspS2, gatA, gatB, gatC
Planktomarina temperata RCA23 aspS2, gatA, gatB, gatC
Planococcus halocryophilus Or1 aspS2, gatA, gatB, gatC
Pleomorphomonas diazotrophica R5-392 aspS2, gatA, gatB, gatC
Polaribacter dokdonensis DSW-5 asnB
Pontibacillus litoralis JSM 072002 aspS2, gatA, gatB, gatC
Pontibacter lucknowensis DM9 aspS2, gatA, gatB, gatC
Pontibacter ramchanderi LP43 aspS2, gatA, gatB, gatC
Pontimonas salivibrio CL-TW6 aspS2, gatA, gatB, gatC
Porphyrobacter dokdonensis DSW-74 aspS2, gatA, gatB, gatC
Pseudoalteromonas arctica A 37-1-2 asnB
Pseudomonas baetica a390 aspS2, gatA, gatB, gatC
Pseudomonas litoralis 2SM5 aspS2, gatA, gatB, gatC
Pseudomonas taeanensis MS-3 aspS2, gatA, gatB, gatC
Pseudovibrio axinellae Ad2 aspS2, gatA, gatB, gatC
Psychrobacter arcticus 273-4 aspS2, gatA, gatB, gatC
Psychrobacter cryohalolentis K5 aspS2, gatA, gatB, gatC
Psychromonas ingrahamii 37 asnB
Psychromonas ossibalaenae JAMM 0738 asnB
Rhizobium freirei PRF 81 aspS2, gatA, gatB, gatC
Rhizobium grahamii CCGE 502 aspS2, gatA, gatB, gatC
Rhizobium subbaraonis JC85 aspS2, gatA, gatB, gatC
Rhodanobacter denitrificans 2APBS1 asnB
Rhodobacter johrii JA192 aspS2, gatA, gatB, gatC
Rhodobacter maris JA276 aspS2, gatA, gatB, gatC
Rhodobacter ovatus JA234 aspS2, gatA, gatB, gatC
Rhodobacter viridis JA737 aspS2, gatA, gatB, gatC
Rhodococcus qingshengii djl-6-2 asnB
Rhodopseudomonas pseudopalustris DSM 123 aspS2, gatA, gatB, gatC
Roseateles aquatilis CCUG 48205 aspS2, gatA, gatB, gatC
Roseivirga spongicola UST030701-084 aspS2, gatA, gatB, gatC
Rubrivirga marina SAORIC-28 asnB
Ruegeria conchae TW15 aspS2, gatA, gatB, gatC
Saccharomonospora marina XMU15 asnB
Salinicoccus carnicancri Crm aspS2, gatA, gatB, gatC
Serinicoccus profundi MCCC 1A05965 aspS2, gatA, gatB, gatC
Shewanella halifaxensis HAW-EB4 asnB
Skermanella stibiiresistens SB22 aspS2, gatA, gatB, gatC
Snodgrassella alvi wkB2 aspS2, gatA, gatB, gatC
Sphaerochaeta globosa Buddy asnB
Sphaerochaeta pleomorpha Grapes asnB
Sphingobium baderi LL03 aspS2, gatA, gatB, gatC
Sphingobium czechense LL01 aspS2, gatA, gatB, gatC
Sphingobium quisquiliarum P25 aspS2, gatA, gatB, gatC
Sphingomonas histidinilytica UM2 aspS2, gatA, gatB, gatC
Sphingomonas indica Dd16 aspS2, gatA, gatB, gatC
Sphingomonas laterariae LNB2 aspS2, gatA, gatB, gatC
Sphingopyxis indica DS15 aspS2, gatA, gatB, gatC
Sphingopyxis terrae UI2 aspS2, gatA, gatB, gatC
Sporolactobacillus vineae SL153 aspS2, gatA, gatB, gatC
Streptacidiphilus oryzae TH49 aspS2, gatA, gatB, gatC
Streptococcus anginosus CCUG 39159 aspS2, gatA, gatB, gatC
Streptococcus massiliensis 4401825 aspS2, gatA, gatB, gatC
Streptococcus oralis 7747 aspS2, gatA, gatB, gatC
Streptococcus oralis AZ_3a aspS2, gatA, gatB, gatC
Streptomyces kebangsaanensis SUK12 aspS2, gatA, gatB, gatC
Succinatimonas hippei YIT 12066 asnB
Sulfurimonas gotlandica GD1 aspS2, gatA, gatB, gatC
Tatumella morbirosei LMG 23360 asnB
Thauera humireducens SgZ-1 aspS2, gatA, gatB, gatC
Thermoactinomyces daqus H-18 aspS2, gatA, gatB, gatC
Thermobifida halotolerans YIM 90462 aspS2, gatA, gatB, gatC
Thermodesulfovibrio aggregans TGE-P1 aspS2, gatA, gatB, gatC
Thermophagus xiamenensis HS1 asnB
Thermovenabulum gondwanense R270 aspS2, gatA, gatB, gatC
Thioclava dalianensis DLFJ1-1 aspS2, gatA, gatB, gatC
Thiohalospira halophila HL 3 aspS2, gatA, gatB, gatC
Tistlia consotensis USBA 355 aspS2, gatA, gatB, gatC
Vagococcus penaei CD276 aspS2, gatA, gatB, gatC
Verminephrobacter eiseniae EF01-2 aspS2, gatA, gatB, gatC
Weissella oryzae SG25 aspS2, gatA, gatB, gatC
Williamsia sterculiae CPCC 203464 aspS2, gatA, gatB, gatC
Yersinia intermedia Y228 asnB

Confidence: high confidence medium confidence low confidence
? – known gap: despite the lack of a good candidate for this step, this organism (or a related organism) performs the pathway

This GapMind analysis is from Jul 26 2024. The underlying query database was built on Jul 25 2024.

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About GapMind

Each pathway is defined by a set of rules based on individual steps or genes. Candidates for each step are identified by using ublast (a fast alternative to protein BLAST) against a database of manually-curated proteins (most of which are experimentally characterized) or by using HMMer with enzyme models (usually from TIGRFam). Ublast hits may be split across two different proteins.

A candidate for a step is "high confidence" if either:

where "other" refers to the best ublast hit to a sequence that is not annotated as performing this step (and is not "ignored").

Otherwise, a candidate is "medium confidence" if either:

Other blast hits with at least 50% coverage are "low confidence."

Steps with no high- or medium-confidence candidates may be considered "gaps." For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, there is a complete high-confidence catabolic pathway (including a transporter) just 38% of the time, and there is a complete medium-confidence pathway 63% of the time. Gaps may be due to:

GapMind relies on the predicted proteins in the genome and does not search the six-frame translation. In most cases, you can search the six-frame translation by clicking on links to Curated BLAST for each step definition (in the per-step page).

For more information, see:

If you notice any errors or omissions in the step descriptions, or any questionable results, please let us know

by Morgan Price, Arkin group, Lawrence Berkeley National Laboratory