Family Search for PF00697 (PRAI)

PF00697 hits 99 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

TrpC / b1262 fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (EC 4.1.1.48; EC 5.3.1.24) from Escherichia coli K-12 substr. MG1655 (see 17 papers)
trpC / P00909 fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (EC 4.1.1.48; EC 5.3.1.24) from Escherichia coli (strain K12) (see 16 papers)
P00909 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Escherichia coli (see 2 papers)
Aligns to 258:449 / 453 (42.4%), covers 99.5% of PF00697, 223.3 bits

TRPF_YEAST / P00912 N-(5'-phosphoribosyl)anthranilate isomerase; PRAI; EC 5.3.1.24 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
Aligns to 24:221 / 224 (88.4%), covers 99.5% of PF00697, 216.3 bits

• catalytic activity: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2- carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate (RHEA:21540)

A0A0H4BJU5 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Saccharomycopsis fibuligera (see paper)
Aligns to 68:246 / 252 (71.0%), covers 85.0% of PF00697, 160.2 bits

trpF / Q56320 phosphoribosylanthranilate isomerase subunit (EC 5.3.1.24) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Aligns to 4:201 / 205 (96.6%), covers 100.0% of PF00697, 157.2 bits

P24920 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Phytophthora parasitica (see paper)
Aligns to 330:513 / 531 (34.7%), covers 80.3% of PF00697, 143.3 bits

PAI2_ARATH / Q42527 N-(5'-phosphoribosyl)anthranilate isomerase 2, chloroplastic; EC 5.3.1.24 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Aligns to 68:269 / 275 (73.5%), covers 99.5% of PF00697, 132.0 bits

• catalytic activity: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2- carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate (RHEA:21540)

PAI1_ARATH / Q42440 N-(5'-phosphoribosyl)anthranilate isomerase 1, chloroplastic; EC 5.3.1.24 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Aligns to 68:269 / 275 (73.5%), covers 99.5% of PF00697, 131.4 bits

• function: Catalyzes the conversion of 5-phosphoribosylanthranilate to l-(O-carboxyphenylamino)-l-deoxyribulose-5-phosphate, which is the third step of the tryptophan biosynthetic pathway.
  catalytic activity: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2- carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate (RHEA:21540)
  disruption phenotype: Bushy morphology, reduced fertility, blue fluorescence under UV light and resistance to the anthranilate analog 6-methylanthranilate.

BT0528 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Bacteroides thetaiotaomicron VPI-5482
Aligns to 7:204 / 207 (95.7%), covers 99.0% of PF00697, 116.4 bits

• mutant phenotype: Important for fitness in most defined media and strongly cofit with anthranilate phosphoribosyltransferase (BT0530). 37% identical to phosphoribosylanthranilate isomerase from Thermotoga maritima (Q56320)

trpF / B0B7P4 phosphoribosylanthranilate isomerase (EC 5.3.1.24; EC 4.2.1.160) from Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) (see paper)
B0B7P4 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase (EC 4.2.1.160); phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Chlamydia trachomatis (see paper)
Aligns to 3:199 / 208 (94.7%), covers 99.0% of PF00697, 113.7 bits

Q8U092 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Pyrococcus furiosus (see paper)
Aligns to 3:202 / 208 (96.2%), covers 99.5% of PF00697, 107.1 bits

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