Family Search for PF03649 (UPF0014)

PF03649 hits 21 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

YbbM / b0491 putative iron ABC exporter membrane subunit FetB from Escherichia coli K-12 substr. MG1655 (see 4 papers)
FETB_ECOLI / P77307 Probable iron export permease protein FetB from Escherichia coli (strain K12) (see paper)
Aligns to 8:245 / 259 (91.9%), covers 99.2% of PF03649, 273.9 bits

• function: Part of the ABC transporter complex FetAB, which is probably involved in iron export and enhances resistance to H(2)O(2)-mediated oxidative stress. Probably responsible for the translocation of the substrate across the membrane.
  subunit: The complex is composed of two ATP-binding proteins (FetA) and two transmembrane proteins (FetB).
  disruption phenotype: Mutant exhibits increased sensitivity to H(2)O(2) stress.

STAR2_ORYSJ / Q5W7C1 UPF0014 membrane protein STAR2; Protein SENSITIVE TO ALUMINUM RHIZOTOXICITY 2 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Aligns to 34:271 / 285 (83.5%), covers 98.3% of PF03649, 230.8 bits

• function: Associates with STAR2 to form a functional transmembrane ABC transporter required for detoxification of aluminum (Al) in roots. Can specifically transport UDP-glucose.
  subunit: Interacts with STAR2.
  disruption phenotype: No visible phenotype under normal growth condition, but strong inhibition of root elongation when grown in the presence of Al.

ALS3_ARATH / Q9ZUT3 Protein ALUMINUM SENSITIVE 3; ABC transporter I family member 16; ABC transporter ABCI.16; AtABCI16; ybbM homolog protein from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Aligns to 22:259 / 273 (87.2%), covers 98.3% of PF03649, 225.4 bits

• function: Required for aluminum (Al) resistance/tolerance, probably by translocating Al from sensitive tissues such as growing roots to tissues less sensisitive to the toxic effects of Al.

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