Family Search for PF06237 (SLC52_ribofla_tr)

PF06237 hits 18 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

S52A3_MOUSE / Q9D6X5 Solute carrier family 52, riboflavin transporter, member 3; Riboflavin transporter 2; RFT2 from Mus musculus (Mouse) (see paper)
Aligns to 1:450 / 460 (97.8%), covers 100.0% of PF06237, 587.9 bits

• function: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)

S52A3_RAT / Q4FZU9 Solute carrier family 52, riboflavin transporter, member 3; Riboflavin transporter 2; rRFT2 from Rattus norvegicus (Rat) (see paper)
Aligns to 1:453 / 463 (97.8%), covers 100.0% of PF06237, 586.5 bits

• function: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)

S52A3_HUMAN / Q9NQ40 Solute carrier family 52, riboflavin transporter, member 3; Riboflavin transporter 2; hRFT2 from Homo sapiens (Human) (see 12 papers)
Aligns to 1:459 / 469 (97.9%), covers 100.0% of PF06237, 574.4 bits

• function: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism (PubMed:20463145, PubMed:22273710, PubMed:24264046, PubMed:27702554). Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption (PubMed:20463145).
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)

S52A2_RAT / B5MEV3 Solute carrier family 52, riboflavin transporter, member 2; Porcine endogenous retrovirus A receptor 2; Protein GPR172B; Riboflavin transporter 1; rRFT1 from Rattus norvegicus (Rat) (see 2 papers)
Aligns to 8:440 / 450 (96.2%), covers 99.5% of PF06237, 512.8 bits

• function: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. May also act as a receptor for 4- hydroxybutyrate.
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)

S52A2_HUMAN / Q9HAB3 Solute carrier family 52, riboflavin transporter, member 2; Porcine endogenous retrovirus A receptor 1; PERV-A receptor 1; Protein GPR172A; Riboflavin transporter 3; hRFT3 from Homo sapiens (Human) (see 9 papers)
Aligns to 8:435 / 445 (96.2%), covers 99.5% of PF06237, 500.9 bits

• function: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism (PubMed:20463145, PubMed:22864630, PubMed:23243084, PubMed:24253200, PubMed:27702554). Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption (PubMed:20463145). May also act as a receptor for 4- hydroxybutyrate (Probable).
  function: (Microbial infection) In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)

S52A1_HUMAN / Q9NWF4 Solute carrier family 52, riboflavin transporter, member 1; Porcine endogenous retrovirus A receptor 2; PERV-A receptor 2; huPAR-2; Protein GPR172B; Riboflavin transporter 1; hRFT1 from Homo sapiens (Human) (see 4 papers)
Aligns to 8:438 / 448 (96.2%), covers 99.5% of PF06237, 498.0 bits

• function: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism (PubMed:18632736, PubMed:20463145). Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption (PubMed:20463145).
  function: (Microbial infection) May function as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)

S52A2_PIG / Q863Y7 Solute carrier family 52, riboflavin transporter, member 2; Endogenous retrovirus A receptor; Protein GPR172B; Riboflavin transporter 1 from Sus scrofa (Pig) (see paper)
Aligns to 8:436 / 446 (96.2%), covers 99.5% of PF06237, 497.9 bits

• function: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. May also act as a receptor for 4- hydroxybutyrate.
  function: (Microbial infection) In case of infection by porcine endogenous retrovirus (PERV-A), acts as a cell receptor to retroviral envelopes.
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)

S52A2_PAPHA / Q863Y8 Solute carrier family 52, riboflavin transporter, member 2; Porcine endogenous retrovirus A receptor 2; PERV-A receptor 2; Protein GPR172B; Riboflavin transporter 1; RFT1 from Papio hamadryas (Hamadryas baboon) (see paper)
Aligns to 8:438 / 448 (96.2%), covers 99.5% of PF06237, 494.9 bits

• function: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. May also act as a receptor for 4- hydroxybutyrate.
  function: (Microbial infection) In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)

S52AA_CAEEL / Q3LFN0 Riboflavin transporter rft-1; Solute carrier family 52, riboflavin transporter rft-1 from Caenorhabditis elegans (see paper)
Aligns to 3:422 / 427 (98.4%), covers 99.5% of PF06237, 458.1 bits

• function: Riboflavin transporter. Riboflavin transport is Na(+)- independent but pH-sensitive.
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)
  disruption phenotype: RNAi-mediated knockdown causes a severe reduction in the number of laid eggs; the few laid eggs fail to hatch.

S52AB_CAEEL / G4SDH4 Riboflavin transporter rft-2; Solute carrier family 52, riboflavin transporter rft-2 from Caenorhabditis elegans (see 2 papers)
Aligns to 3:468 / 476 (97.9%), covers 99.8% of PF06237, 440.7 bits

• function: Riboflavin transporter.
  catalytic activity: riboflavin(in) = riboflavin(out) (RHEA:35015)
  disruption phenotype: RNAi-mediated knockdown causes a severe reduction in the number of laid eggs.

Or search for genetic data about PF06237 in the Fitness Browser